Document 7OE88b5R5p1jBmbkN2r1D5vaa
T7iS
Liver Angiosarcoma Cages
received
r\ i
Circulation
JAN 2 58S
Dr A Rosa Adams, Air Produces Dr P N Anderson, Wilton Dr I M M Bagshaw, Norsk Hydro Dr W C Barnes Jr, Monsanto, USA Dr John T Barr, Air Products Dr G 3arrat, A.E-C.R.P* Dr Peter 3axter, EMAS Dr M 3enech Naphtachimie Dr B Bennett, ICI EiUkouse Dr P Bertazzi, Milan University Dr Eesche, Dynaoiit Nobel, Troisdorf
Dr C Bishop, EMAS Dr D Bryson, Agricultural Div'n, ICI Mr David Burgess, ICI Americas Dr David Syren, Kemanord Dr J T Carter, EMA3 Mr C Celia, Eaiohem Polimeri Mr H Chance, VCM Technical Manager, Mond
R. W. FR^SE Prof C Maltoni, Bologna Prof Lo Martire, Medil-Anic-S, Milan Dr R Mattiussi, Montedison Mr D Middleton, Norsk Hydro ,Mr Mokka, Neste Oy Dr R Hontesano, larc, Lyons Dr A A Motti, Duperial SAIC, Buenoa Aires Dr A Munn, Monsanto, Brussels Mr M Munoz Mouton, Rio Rodano Mr S Nakamura, Japanese PVC Association Mr H G Olson, Louisiana Dr J J O'Sullivan, ICI Mond Dr R Owen, TUC Dr G M Paddle, Central Medical Group, ICI Dr S Pegiialunga, Montedison Dr Hans Popper, Mount Sinai Medical Centre Dr J Possberg, Vacker Dr A M Puech, Atochem
Mr P G Claus, AFHE
Dr J Purdham, Canadian Centre for CHS
Mr H Clayton, Norsk Hydro Dr J C Contaa30t, Chloe Chimie, St Fons Mr J G Davies, Everberg (2) Dr De Sloover, Solvay Sir Richard Doll, Warden, Green College, Oxford
Mr G Dupont, APME Mr H Emminger, VO Dr V Ernst, Nurnberg Dr H Falk, CDC Atlanta Dr D M Ferguson, ICI Americas Dr H P Friedal, Heidelberg Prof L Golberg, Durham, North Carolina, USA Dr R S Gosztonyi Jr, Tenneco Chemicals, Saddle Brook <NJ)
Dr J Rambaud, RP Recherches Mr P Rangnes, Norsk Hydro Dr P Richard, Rhone Poulenc Dr J Ruty, Atochem Dr J Salg, Niosh, Cincinnati Dr R Saracci, larc, Lyons Dr M L Scheffers, DSM/CVMD, Holland Dr David Seronne, Diamond Shamrock Dr J Sigrist, Shell Chimie Dr Paul M Smith, Llandough Hospital Dr S Spirtas, NCI/NIH Bethesda Dr Carol Stack, CMA Washington Dr J Stafford, UK
Dr Valter D Harris, Uniroyal Inc Dr Donald W Hillman, Diamond Shamrock Dr Robert K Hinderer, BF Goodrich, Cleveland Mr J Hodgson, EMAS Dr W A Hogg, Imperial Oil Ltd, Canada
Mr Stahnecker, BASF Prof C H Tamburro, University of Louisville Dr Gary Ter Haar, Ethyl Corporation Dr B Terwiesch, CWH Dr Gilles Theriault, McGill University
Dr J K Howard, Wellington, New Zealand Dr N F Humphry, Melbourne, Australia
Prof Dr Thiess, BASF Dr E Thiis Svensen, Norsk Hydro
Mr J Jauvert, Chloe Chimie, Paris
Dr W Tordoir, Shell
Mr K R Jervis, Hillbank Dr M N Johnson, BF Goodrich
Dr T R Torkelson, Dow Dr H J Van der Merve, Sasolburg, South Africa
Dr 3ruce Karrh, Dupont
Dr R A Krueger, BF Goodrich
Dr J P Laloine, Solvay
^)r R W Laundrie, Akron, Ohio
Mr J Lawrence, SPI Dr F I Lee, Victoria Hospital, Blackpool
Mr J R Wallace, Esso Chemical, Sarnia, Canada Mr H Waltemate, BF Goodrich, Cleveland Mr S 0 Weidling, Kemanord Dr D J `Wheeler, ICI Hillhouse Mr R N 'Wheeler, UCC Dr J Vtistan, ICI Hillhouse
Prof W K Lelbach, University of Bonn
Mr K H 'White, Duperial SAIC, Buenos Aires
Dr G Leveque, CDF Chimie, AZF
Dr D M J Williams, 3P Barry
Dr D Levison, St. Bartholomew's Hospital, London
Dr K S Williamson, Central Medical Group, ICI
Dr P Lewis, CIA
Prof R Wilson, Harvard University
Mr Lolivier, Solvay Dr J Lussato, Atochem
Dr A P Wright, P & P Division, Wilton Mr John York, Everberg
Prof R N M MacSween, Western Infirmary, Glasgow
Dr J M Maillard, Luzern, Switzerland
BE
(From : Dr B Bennett, Meuical Department, Imperial Chemical Industries ?LC, Hillhouse Site, PO Box k, Thcmton-Cleveleys. Blackpool FY? 4QD, United Kingdom )
14 Jan 1935
T or T')1
sr;;/-' .
" 1 ' ',1'" ' \
1 i
I)lire
(l-l.
____________
\JC "Pr<-<vitiH "VastuS
/ ~ -3SZ -
___________________
Vi | "\
GENC 007928
PREFACE
ACKNOWLEDGEMENTS, SIGNIFICANT CHANGES AND COMMENTS
1. The new cases in the Register are the following
Belgium UK USA USA
02 10
37 38
2. It should be noted that there are corrections from the previous Register against the following cases :
France UK USA
16 07 14, 15,
35
3* I would like to thank John Barr for the Plant corrections that are in that Section.
4. I would like to thank Dr. De Sloover, Dr. D. M, J. Williams and Dr. M. N. Johnson, together with Mr. John Barr?
for informing me of new cases.
^
5- For the case corrections, I would like to thank Dr. J. C. Contassot, Dr. D. M. J. Williams and Dr. M. N. Johnson
6. I would especially like to thank Dr. Joyce A Salg for the great deal of effort which she put into clarifying USA 14 and 15, which had previously been documented as dubious fabrication cases.
7. I should be very grateful if all the recipients of the Register could continue to keep me totally informed of any new cases or, if they should hear of other Companies who have acquired a case of ASL, it would be much appreciated if I could be informed by the appropriate person.
8. With reference to the Register format, I will be continually trying to improve it.
J r.-
B BENNETT 14 Jan 1985
Gene
'&
Index
Table Sequence
Belgium
Canada
Czechoslovakia
Trance
Germany
Italy
Japan
Norway
Sweden
UK
USA
Yugoslavia
Incidence of Cases pa (Table 1)
Distribution of Cases
by Country
(Table 2)
Pattern of Cases by
Factory
(Table 3)
Latency Periods (Table 4A)
Distribution of Latency Periods (Table 4B-4M)
Annual Geographical Incidence (Table 5)
PETROCHEMICALS AND PLASTICS DIVISION LIVER ANGIOSARCOMA CASES (REVIEW DATE - 1 JANUARY 1965)
1
2-3
5-8 9-13 14 15 16 17 18-20 21-27' 28 29
30
31
32 33-39
40
ASL Case Numbers by year of Death (Table 6)
ASL Case Numbers by year of first exposure (Table 7)
Western Europe PVC Producers - Start-up Dates vs ASL Cases (Table 8)
USA PVC Producers - Start-up Dates vs ASL Cases (Table 9)
Canadian PVC Producers - Start-up Dates vs ASL Cases (Table 10)
East European PVC Producers - Start-up Dates vs ASL Cases (Table 11)
Japanese PVC Producers - Start-up Dates vs ASL Cases (Table 12)
South 6 Central American PVC Producers - Start-Up Dates (Table 13)
41 42 43 44-45 46 47 48 49
OENC 00??30
iMibuiAj. oiKHir/u. iNiuiaruiKS nr: l`KTN('CHEMICALS AND Pf.A.S fi rJ:S DIVISION
LIVKH Ang loud rcuuui
ftatei l Jumiury 19HS)
Pagt* l
CUCNfKY AND RKb'EMENCK
NAHK OH INITIALS
DATE OP BIRTH
Sol way
29.U9.4U SuJvay
__L
| fIKS? VC j DATE OP FACTOR? | EXPOSURE j DIAGNOSIS
l\
ACE AT
niACNosrs
YEARS OK EXPOSURE TO
DIAGNOSIS
YEARS OK EXPOSURE
DATE OK DEATH
HISTOLOGICAL | ESTIMATED CONFIRMATION j EXPOSURE
| LEVEJ
OTHER
CAREER
HIGHLIGHTS
] j
OTHER COHMEHTS
Jt II Jeaeppd | 00.07.SS | 00.05.76
29 .06.76
I
\ lilfcii Autocleaner I U yre
| 195ft-196A
[ eapoaml to Polyworker
| 200 ppM 3 yra
j far B Sru | per day
| and
| cariuhiLy | under
| SOU pp*
| 111 6 to J 9**
| autoclave*
J J 968--19 72 J expouuJ to
I 50-200 ppa
| B lire per \ Jay In j 25a1
| autoclavee | 1972-197T*
J uxpoaed to j 50-200 pi**
| In auto-
[ clave rooa
| l?74M00
J HP* J 1475- 50
I PI* | RETIRED | 1 Keb 1975
Driller In foundry (2 yra) Karaur <15 yre) Work In gta**
Irnl. A clieuI -
cel Industry
i I [Hepatic teatd |ln Oct 1974 [were noraal (Re t i red [Keb 1975 lltodpltal lied |Kay 1976
I |Complete |Clln1cal end |cereer Jetallt |ere given In i j paper by
|Hulilet ec al | In Aruli. Belg
|Ked. Sue.,
|ILyg. Med. |Trav. Hed. |LeK. |1977 page* 1601-622 J
I
Jtaeppe \ 20.08.62 | 00.10.79
23.|G S3
Yu*
A_____
j 0&,6d t <0.63
. oi.6? .
) w.10.71 200 | & Li./dey
j U4.6J i i2.a I ^ 2I.IG ppu
i
I
Antucteener Flraaen ulnre | let ujgn July
5 yre 5 alba 10,71 .
j 791 Thoracic
Operator
|pain 07. 79.
3 yie 9ia(liu.
|Hepatic Leuta [altered 10.79
[PoultIve
| echography
111.79. Hepj-
J tec tnay 02,60
[ ['.lieuotWmpy.
| Jnfurumitun
| g l veil 111
llettet 12 Nuv jI9H4 froa
GENC 007931
|Dr SI
Jfll'l-'KIAJ. ClIKEIICAI. INIHIH'I kiks Vl.C PhtRUttlhHlCAI,:! AN LI PlASTJCd DIVISION
LIVtR AikgtoKAfcoua Caaes - (Review Outei L Jin 1995)
Canada Sheet l
higa 2
GEtdC 007932
cuurffKr AMD
HEPSHENCE NO
NAME OR INITIALS
HATE or BIRTJI
iHi'Klf I Al- CMPM I GAL JNPUM'HJKS PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER Angloaarcnaa Caees - (Review flute* l Jan I$fi5)
N1
FIRST VC EXPOSURE
DATE Or
DIAGNOSIS
AGE AT HI AGNOSIS
YEARS Of
EXPOSURE TO niACNosrs
YEARS Or EXPOSURE
DATE OP j| HISTOLOGICAL OR ATI! | CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
Sheet 2
Canada
1
OTHER CAREER HIGHLIGHTS
OTHER COMMENTS r
1976
Reactor cleaner
Furnace op.
aloteoanco,
packaging
GENC 007933
uimiMi. oikhi Gai.
pi.c
** k: r k< i cm km r ca i .s ana plash cs division
LJVEK Any I osa reouta Cases - (Review DjC: 1 Jan 198*5)
Page 4
U
COUNTRY ANO
MJifiCHIsNOE
HU
NAH UK INITIALS
HATH UP blKTH
COMPANY
PINST vc EXPOSURE
JJATK iif DIAGNOSIS
AG I! AT DIAGNOSIS
YEARS OP EXPOSURE TO
DIAGNOSIS
YEARS OP EXPOSURE
DATE OP DEATH
UISrOLDC ICAl. CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAttEER HIGHLIGHTS
OTItER COMMENTS
Novaky
Novaky
27.IL.64
16 16 24.12,71 26.11.64
Autoclave Cleaner
TARC letter of 1-4-S2 Riving detal La froia Prof A David of Centre Ind Hygiene and Occ diseases.
Autoclave Cleaner
IAHC letter oJ 1-4-A2 gave soaewha C a leered da tee for elite case. I have
accepted Che changes since the dates cone froia Prof A David of die Centre of Industrial
Hygiene and
Occupational Diseases. Hy
dates coue orlgIHa 11y f run HI OS II
6ENC 00 ?34
coiphtrv Am
KEFkKEMCH NCI
NAME (Hi INITIALS
IMTK OF HUTH
FRANCE 01
5.04.24
lnmtiAi njinio,L innustaos tN.c
jjKTi>ctip>rrcAi.s and plastics division
LIVER Angiosarcoma Cases - (Review Date: l Jan 19115)
Fra tied Sheet
Pago 5
Rouss illon
FIRST VC EXPOSURE.
DATE OF lUAOHHSIS
AOK AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF
EXPOSURE
DATE OF MATH
His*rnjrnciCAi.
CONFIRMATION
ESTIMATED j
EXPOSURE | OCCUPATION LEVEL j
_______ !_______
Higli
1 I
(Autoclave | worker and
leleaner
J19 yra
I
OTHER CAREER
HIGHLIGHTS
| j
j
OTHER COMMENTS
\
I
|Ref. Ravier et jal Arch. Hal.
fProf. I 30 n'
| 3 Huy 75 |p 171-177
ttrlgnoud
15.01.75
Yea (NIOSN no
conusant)
High
|2 yre on laonouer 110 yrs on Ipolyaer| laatlon
i
Italian
origin
|Hef. |C Bonneton et
|a 1 "Nouvulle |presse |neJlcala"
|5 Hov 1977 |p 735
Hrignoud 19.10.49 L6.01.76
04 .01.76
High
|Polyworker 110 yrst aa lautoclave Jclaaner | Coapo uniting |) yes
VCH productlon|Ref. Recy et 16 yrj a l Arch. Hal.
Italian POW |Prof. 1 37 n'
Shepherd,
|6 June 7?
Sawyer, Hu eon Jp 551-555
i
High jNonooer
(production
(worker |fl yr
IPVC
|f1ltratlon |ia yr.
ttrlguoud
13.05.76
High
SENq 80?p?t
| Polyworker
III yrs
1)Thoracoto*y (Ref. P Coudere
9tlr Feb 1976 (at al "Setsalnu
costal
(dee hoepltaux
angloeurcoua |10 Septeabre
2)Sclntlgraphy|1976
found ASL
(Previously hail
3)7laeMo r rhage J bone
fro* AST.
| angiosarcoma*
4 )Rlglit
|Aluo
llcpatecinhiy JPfHchowHkf el
|ill "La Honvulle
fPrcuue Hctllc* le
fill y 1979 |
4fl5____ | J
iHrKKlAI DHvMICAI. INhllSTUiES l*|.c
FETROCI IKK 1 CALS AND PLASTICS DIVISION
I.IVKIt Angloaarcoaa Caaea - (Review tUte: 1 Jan I9fl5)
fra nee Sheet 2
Page 6
COUNTRY AND
REfEKttHCK
NO
NAME OK INITIALS
PATE Of BIRTH
FIRST VC
EXPOSURE
PATE Of IHACNDSIS
AGE AT diagnosis
YKAJiS OF
EXPOSURE TO
DIAGNOSIS
YEARS DP EXPOSURE
PATE Of
DEATH
histological CONFIRMATION
ESTIMATED
EXPOSURE
LEVEL
OTHER CAREER
HICHLfCHTS
| j
j
OTHER COHHENTS
flrlgnoud
11.09*76
( NfOSlI
aayu 12.09.76)
Moderate
(1958-1960)
2 jrs
filtration 10-11 yre
polyworker end worka lahT
t
\ |7tile aan had |AOL prior to |AS* Ann. de (Hal. Prof. |July '77 |p 645 I. 6. | ADI. wae found
|in 1971 five |yr liefore j ASL
CL.04.14 Solvey
After
ileath
N [OSH a aya 00.07.76
03.12.75
Yee (NfOSlI no
couneil t)
30.01.77
High
Plant forean In polyeertaatlon
1972-6 a.hatn uecclon la St Aubun
jDled of leeptlceeele jSaaII liver
jleeloa found jafter autopay
Moderate
6 yra packer 6 autoclave clnr 14 yra autoclave worker
fliad been [tunnel worker Iprevloualy
I
18*10.14
St foo*
10.01.48 26.04.76
J_______ L
Very High 1948-1966 Leaner Expoaure 1966-1976
Polyeerlaatlon operator, autocleener autoclave Maintenance
10 yra In sulphuric acid factory, etorekeeper I general eervlcee
[Operated 4.76 [for ruaoval o| Ituaour froa Jllver and Idled after [aecond Jeurgtcel [operation for jblllo
[branchial jfistula
j Paper by
|Hr Kety t at |In Aruhlvea de |Ha ladea JProfeadJonala |Vol 40 No 6 j1979 pugaa
GENC 007936
IMP Ell ME. ClN.HfCAt, INWJ STRIPS tl.C PLfJUirHErtlCAJ.S AND PLAN rids DIVISION
LIVKH Angloujreoma C.iaeu - (Review Hate: l Jan 1985)
Fra nets Slice C 3
Page 7
CIJUN'J'KY AHU REFERENCE
NANS UK INITIALS
DATE OP b I KTK
FIRST VC
EXPOSURE
DATE OF DIAGNOSIS
AGE AT DIAGNOSIS
YEARS OF EXPOSUKE TO
DIAGNOSIS
YEARS OP EXPOSURE
DATK OP \ HISrOLOGICAI. DEATH | CONFIRMATION
----------------- 1-------------------- [----- 1--------------
P.ST1HATK0 |
|
EXPOSURE j OCCUPATION j
OTIIKK CAREER
LEVEL j
| HKTIl LIGHTS
16
OTHER COMMENTS
*4.05.19
15.02.12
66
Brlgnoud 09.02.49
~TT
T9.oi.3i Solvuy
21.09.6T 26,06.79
Chloe Hi i it I a ( Fu riuu r I y
*[')
1943
oo.oTaT
"5cT
l I
10.01.7fl [ J
1 I
~T} 23*06.79 | Yea"" I I
22.08*79
GEMC 007937
nigh
lAutoclave (cleaner
t
I I
JIO yra In
Jaechanlcal
(engineering
(Induetry
{1946-1956
Died of
puliaonery enboll&a 5
days after
Margery
High
|l94)-)946
| polyaer-
(leutlon
|general
| purpode
| worker
11946-1972
IVCM
layntlieale
|(HCl 6
|Acetylene)
| Foresail
J(agent
jde ad Itrlae
(1972
jretired
i
j
High ry ltl(h
I
|Monoer
[~
(production |
land polyner-l
Jlsatlon
J
operator
jAutocleaner |2 yra aa cycle Cigarette
|2 yra,
tMechanic.
eMoker until
fAuto-
(10 yra aa
1974. Ill all
(operator
lenaneller In of 1977 due to
J9 yra, (Copolyaera \A yra
I
Jaaiiltary ware
(Manufacture t
Oeuophageal varlcea. Surgical InterventIon
25.05.79
|mj-]97s [HJS-1979
[rljlit
iejjfl Ccc toay )
1943-1975 [Alt typea of(aalnteuancu
and
Ijoba on
(work
Intera[ct-|uidiiufacturM (
ently
|4 Maintenance
1975-1979 jin VPM Poly |
jProceuu
(
at
JMHlH. j Kil-'S
PLASTICS DIVISION
I.TVKK AmkI^Karct>jiJ Gas, erf - (Heview Date; I Tan 1985)
franco
Shoo C 4
Page fl
i 1 (2
i1
GODN'JKY AND j NAME OR RtHiKtriCK J INITIALS
NU i
i 1
France
i
1
DATE OK HIKTIi
45
_______J_
1
1
7 L
COMPANY | FACTORY
FIRST VC exposure
HATE OF DIAGNOSIS
4_ 1
IS |t>ep
i i
j \ 1 i 1 16 |OTH
1 i 1 1 1 |
i i l 1 17 | UAH
1 1 l
01.01.17
Chloe
t St Fona
Chlale
(formerly
RP)
07 .07.55 28.09.82
11.07.22
CL loo
Chtmte (Porucrly
RH)
i Sl FonB
*7.10.41 05.01.81
J-J________
22.02.21
CUoe
1st Fons
Tkiinle
(Fo rwer ly
HP)
17.06.48 03.04.81
i
l l i i 1 i i l l i l 1 i i i i i _____l
6 ACE AT DIACNOSIS
45
61
60
V YEARS OF EXPOSHKE in DIAGNOSIS
27
41
34
10 ..
VtAKS OF EXPOSURE
U
DATE OF DEATH
..
12
IIIST0U1CJCAL CONFIRMATION
n1 I 1 14 1
I i1
ESTIMATED I
|
EXPOSURE | OCCUPATION J
LEVEL i
|
11 iJ
13 [ i1
OTHER CAREER HIGHLIGHTS
I j
16
OTHER comments
| 1i
I 1
27 Alive
Yea
1____ IK 03.06.811.
Yea
ii
1 Hlgli-2Q jrr (Autoclave
1 f
(J G Contaseot I
Moderete 7 yrs
{cleaner 11955-1962
i i
|Letter of JS 10 1981
j |
| autoclave
| operator j1962-1982
i i i
i 1i-------------------------- i1
ii
lljgh-31 yrs|PolyerIeat
I Ret(red
j
Moderate'* [Ion Process
Low - 5 yrs |Hati
i | Maintenance jllorker
i t i i i
| Jan 1979.
|
|J C Coiitassot |
|Lettera of
j
|5 10 1983 end (
125 7 84.
\
i
28 03.04.81
Ye*
|Health &
i
{Safety Agent|
--1--------------------- 1--------------------------
High 23 yrs
|Autoclave jcieaner
|Other sectors |Retired
jof St Foue
101.01.79
| j
11948-1971
i i
(Factory 1971- |J C Contaeaot (
j 1978
(Letter of
|
t
(5 10 1963
|
ii
ii
ii
ii
ii
ii
ii
ii ii
tt
ti
)i
ii
ii
ii
i
ii
ii
Jj
G%
0?93,
lMJ'KktAI. CllKHICiU, mOHSl'KlES Ki.C EKTKOClHvHlOAl.S AND PLASTICS DIVISION
LIVER Angtoedrcona Curies - (Review Date: l Jan lOf!5)
Ceritany Sheet l
Pafl* 9
11
2
!1 J1 | COUNTRY AMI)
NAME OH
| REFERENCE j NO
INITIALS
1 1 ICEHHANY
1 1
1 01 1 i I 02 1
(!] i
1 1
i I o4
1
1 t 1
DATE OF BIRTH
j. 1
i 4 |5
! ............... 1
t COMPANY |
i J
1
FACTORY
6
PI It ST VC EXPOSURE
i
7
a 1 9 t 10
11
__ ___ ,
______1_____________
DATE OF DIAGNOSIS
ACK AT
j YEARS OF
| YEARS OP
DIAGNOSIS | EXPOSURE TO | EXPOSURE j D1ACNOSIS i
DATE OP DEATH
1_____________
12
UtSTOLOOTCAL CONFIRMATION
i nt
1 1
i U|
1 i
ESTIMATE!! (
|
EXPOSURE ) OCCUPATION j
LEVEL 1
1
1i
r IS 1
i
OTHER CAREER
HIOULICflTS
| j
i | 1
16
OTHER COMMENTS
i
00.00.30 Dynuulc 1
00.00.31 Dynuiat L 00.00.30 Dynamic
00.00.30 Hacker
|Troladorf 01,10.56 j
19.09.66
1 [Troladorf 14.10.57
j ______________ 1 1
25.09.70
iRheJnfelJden i i i i i i I i
1 |
i \ 1 1 1 i i |Hurn| hausen 1 1 1 1 i t i i i t i i i i i i
09.06.52 16.04.57
00.01.73 26.11.74
1
1
ii
i
36 I 12
I 12
25.01.69 Yea (NlOStl)
tI |Polyworker )
i i
J 1
_____________
!1 ii
l 1
19 i
J 1
43 1 1
>1 21
1n
14.12.71 Ye. (NIOSIJ)
___________________
1 16 1
10.10.71 Yea (HIOSII)
fPolyworker [ 11 1t
'
JFilling
|
IpeetUide |
i
1i jAepurted tinderl |non polyaer-
1
(aeroaut canal
|Jaatfon
1
(with VC
j
|workers In
1
ii
iNtOSIt list of
1
ii
1)1.3.77.
1
ii
|Thls of couraej
1
ii
(Is atrJcL Ly
1
ii
[correct.
ti
|However I
1
ii
|wonder
1
ii
|whether thla
ii
(uau had high
I
.I
|
lexpoeitra to
ii
IVCH In 111.
ti
Jean fllllng
I
ii
(operationT
|ii
1
H
J
|--------------------------- i----------------------------
44 1 n
17
25.11.74 Yea (HIOSII)
206-500 ppui| Polyworker 4)1958 wee
ICllnlcai
Jbut hlfl.li
(teuporary Jautocleaner
jdetallu In
(during 1 yrjriutocleaner |for 1 yr
J paper by
autocleanerj
[
jCokel et a]
ii
(Virchow* Arch
ti
|A Path 1976
ii
(372 p 195-203
i
(i
1
ii
1
ii
1
i i i i i
i
_________ ______________
ii ti ii ii ii it ii i JI
1 1 1 1
1 1 1
J__________
GENC 00793?
9
I
IMPERIAL CHEMICAL INDUSTltrKS PLC PHrMOClIFMICALS AMO PUSTJCS limSION
LIVER Anglos arcaiea Cnuea - (Review Hate: 1 Jen 19115)
Ceram ny Sheet 2
Page IQ
COUNTRY AND &EFEKKNCE
HO
J9AH
IHlTiA
HATH OP
BIRTH
(NIOSil given an Cduc 06)
00.00.36
(NJOSM gIvee js Cuee 05)
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FIRST VC
DATE OF l AGE AT t YEARS OF | TEAKS or | OATH OF 1 HISTOLOGICAL. ESTIMATED |
1
EXPOSURE DIAGNOSIS i DIAGNOSIS i EXPOSHHE TO i EXKOSMUs | DEATH | CONFIRMATION EXPOSURE | OCCUPATION J
i|
OTHER CARE.EH
| OTHER | OOHHBNTS
i
i
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ti
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1 HIGHLIGHTS J
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ii1 ii 1
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49
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| |
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11.7ft. 1 don111| [think elite la j
(a correct
|
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|an uy have J
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| In VCH
i
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for In *aln
|
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|
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GENC 007940
IMPERIAL CHEMICAL INDUSTRIES PLC I*ETKuCltKMICALS ANN ELASTICS LI[VISION LIVER Angloearcona Canes - (Review Date: 1 Jan 1985)
Ceruany Sheet 3
Page n
I___________ I
J COUNTRY AMU j REFERENCE
| NO
I_______
\ |CfKHANY
J OS
NAME OR initials
DATE <]y iiiRru
I
I 10
|(N10SM given | an Caao 10
I I
[ II
l(NIOSH glvua | an Case 10)
I I
bucg6auaen
Oyiimnl t
EJ HST VC
EXPOSURE
DAVE OF DIAGNOSIS
ACE AT diagnosis
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
I
ESTIMATED | EXPOSURE | OCCUPATION
LEVEL j
OTHER CAREER HICHLICHTS
OTHER COMMENTS
i i
16.06.76
47
07.03.77 2fl.06.77
I I
tgli pe&ke |12 yra poly|worker loci |17X auto|clave (cleaning (Control room
n /r I I
High peak a |]0 yra polyjuorker Incl j]71 auto-
Iclave (cleaning J
t
High
|3 yra auto* Iclave (cleaner (19 yra (filter (operator
tn/7B
|[
ConMraed
j'
Average
tposure flrt yra 160 ppu
:c LOGO ppa
Next 1 yra ai
75 ppa. Laat
yr av 35 ppa
I
Average
]
exposure ftratj
9 yra l 50 p|M, (
occ 1000 ppu.j
Laat yr av
(
76 pp<a. CUM 1
letter of
|
2l.04.7fl
|
07.10,77
(PVC Menujfacture
| Autoclave
|worker for
J6 jra I I
I....... ...................._.!__
GEHC 007941
IMPERIAL CHEMICAL 1NIHJSTK [ KS Pl.C PETROCHEMICALS A Nil PLASTICS DIVISION
Germany SI met 4
Page 12
LIVKR Angiosarcoma Cases - (Review Date:
Jan 1985}
1l
i1
I31
l |COUNTRY AND T NAME OR | DATS OF |
| REFERENCE j NO
INITIALS | BIRTH J ii
A COMPANY
1 ii T I1
[GERMANY 1 1J I 14
| 15
ii
JJ |00.00.14 | Loiizj
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KNUtSII glveul |thls as |Case H)
1 I*
i i
ii
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ii ii
ti
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_____ _4
_J
100.00.21 f Dymualt
ii ii
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t3 | 6 | 7
8i
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1
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ACK AT I YEARS OF
j FACTORY | EXPOSURE | DIAGNOSIS orACNOS IS i EXPOSURE. TO
ii
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11 i
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1 12 110 | U
13 | 14 i 15 1 15
1 J__________ L_____________ |______________
4
YEARS OF l DATE OF | IS ISTO LOCI CAL | ESTIMATED |
OTHER
| OTHER
I t [
EXPOSURE |
i
| t
OPATM
| crwFiswA'rinN I
Ji1 1
EXPOSURE LEVEL
[ OCCUPATION [
CAREER HIGHLIGHTS
| 4_ 1i
J
i i 1
COMMENTS
|
i i
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l* U9.05.7A 1
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i (of 21 12 fllt t
i
|Hr Frtedel
|
t |aald this was | i [a "Plflttenepl-j
i [thelkarxinom l
i t*t
|
t ISpelaerohre* [
i |(a carcinoma [
i
|of the
|
i [oesophagus) [
i [not attrllmt- l i [able Co VCM t |
i [not recognised|
i [as an Indust- [
i [rial disease |
25
j j23.10.7B
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7
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i i i t i i i i i i i i t i i i i
[Autoclave
4_ l
1 T
ii i|
j7 U Beet
|
jletter of
f
jJOtl. Juno I960,
[enclosing data}
j f roe
|
j Hr H F KrUdelt
[of B0 Cheiale 1
|F H Beat
i
[letter of
[
|30th June 193n[
[enclosing data}
jfroe
j
[h V Frt.del of[
[BC Cheiale [withdrawing
| [
] Chi a case
[
ii
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1 | Angiosarcoma |
tt i1 it
1 [cleaner and 1 [worker. 1 [Drier
[confirmed
|
109/79. Sosa j
[detail of tills]
i1 i1
i1 i1 !1 20 |o7.oa.?a 1
T.a
1 [operator. t [Later shift 1 [leader 1t 11
T1 High [Autoclave
|i also cases | [9> 11, 15, 16 j
|& 17 given In ( [NRH Report for|
197H |Angiosarcoma J
i
JASL and
|
i [Uepatecellularj
i
[Card now*
J
Jworker till [tm. [Leader and
IcunfLreed, [full details
|of tllneaa
) f
|
it ii ii ii ii
i Juaater
[since March [
ii ii
11973 given In | j NECU Hcd Imp j
ii ii
1 [Rep for I97fl, [
[Different
j
ii
ii
ii
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[details given J
jIn "VC
j
[Associated [Disease* by [Lelbach and [Marstellcr
| | ] f
Kn n/i. i
IMPERIAL CVlKMICAL JNIlIJiSTK TKS PLC PKrjtiiCUfitfUJALS A Nil ELASTICS DIVISION
LIVER Anglogarcoma Caaee - (Review Date: l Jan 19H5)
Curuny Sheet 5
Page 11
16
COUNTRY AND REFERENCE NO
NAME Ott
INITIALS
GERMANY
l? (HIOSH glvea an Cunt: IS)
DATE Itf BlitTil
Dyudialt
| | FIRST VC | FACTORY | EXPOSURE
II J_____________I "I-------------------- !------------------
I(
II
iTroLadurfl Ol.ll.61
DATE OF OJAGNOSIS
14.OH.78
00.00.13
Hocchat
I
IfJeiidorf j 00-00,55 (I
25,12.29
00.00.25 00.00-15
00.00.21
Dynault(TroladorfJ
li
Jt
JI
Dynamic
l [TrolsdorfJ
18.10-54 14.02.61
Dynuult
IJ IJ II fI
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01.01-62
Dyijjmlt
II
fI II I!
I JlToladur f T IS.IO.fTT
(I
II
_______ l______ J______
00.08779
00.09.79
pronounced
clinical liver
ayintoiM) TJrn'Tfl0
ACE AT DIAGNOSIS
"fTT
YEARS OF f YEARS OF KXEUSUKE TO j EXPOSURE
DIAGNOSIS |
! I--------------------
DATE OF DEATH
HISTOLOGICAL | CONFIRMATION j
(
ESTIMATED|
[
EXPOSUREj OCCUPATION j
LEVEL|
j
OTHER CAREER HIGHLIGHTS
| | |
OTHER COMMENTS
28.OR.78
High |Autoclave
I | Artglosarcona
|worker
Jconflreed
(Annual report
fof the Nortli
t Rh C no
|Weatplia] la
iMedlcal
| Inspectorate
|for 1978
|page* 147-377
Iglvee full
IdetaLle. Vinyl
Ichlortrie
Idlaeeae
|dJugnused
102-02-71.
|0eei>phagea1
Ivarlcea.
|8adlologlc*11]
(confirmed aero
24 25-12.79
|Autoclave
Joateolyalg.
I
(Worker
1
25
22.02.60
Yea f High IAutoclave\
I Dr ftesche
Metaetaelng j
(Worker
|
jlrter of
ASL
j
i
i
1)3-04-82 [
ii
i
|Dr W C K jUima
Yea
f
(aeeaiiglo
|
Endothelioma J
of liver with j
Metaataaeg
(
Ugh
jAutoclave (Worker
I(
(Dr Stische jletter of
113-04-82 to (Dr W C F Adaaa i
U 19.06-80
Yea T IJIgli(Autoclave f
laeaangEo
J
| Worker ami |
[ndn the I loaa f of liver with j
Jworked In J (drying aliop [
etaetaaea
J
I
I
|Or Besche (letter of 113-04-82 to I Dr W C F Adame /
oTTOi
Yea
etMutaatng SI,
(
| j
1
QNC 007943
Ugh
(Autoclave (Worker
[Cliargehand, f mibwe^uunt I y lEorcman
J_________
[Or Betiche | Let lor of jn-04-82 to | Dr W V, 9 Adumu
O
IMPERIAL CHEMICAL IHIUISTH IKS PI C PKTtttWllPMICALS AND PLASTICS DIVISION
LIVER Angiosarcoma Canes - (Review Date: l Jan 1985)
* Should thle case be reeved from the llat? NlOSH have It on their aupplementary list relating to non-polymerlsatlon workers exposed to VCH.
JS l/fl/77
Page 14
COUNTRY AND
MEFEKKNCK
HD
NAME OR INITIALS
DATE OP MHTH
ITALY
01
(On N10SII supple ment ary
lUc)
13
FIRST VC EXPOSURE
DATE Of DIAGNOSIS
ACE AT DIAGNOSIS
YEARS OP
EXPOSURE TO
01ACHOSTS
YEARS OP RKPI1 SURE
DATE OP DEATJI
16.04.71
HISTOLOGICAL CONFIRMATION
ESTTHATED (
|
EXPOSURE J OCCUPATION J
LEVEL j
|
.!_________ L
I I
|PVC Bag
jextruder
OTHER
CAREER HIGHLIGHTS
OTHER COMMENTS
Primary tumour may Lave been pericardium. Not hornogeneoua with other ca sea.
*a **
3.11.29 Solvey
Porto Ma rghera
20.07.57
00.04.59
43
27.12.72 10.07.75
Hire Venice
See Heltunl Med dJ Uvoro 65 p445. 1974. Further details in letter from Dr Nontenant* of IARC on Apr let I9A7. Alao su Haltoni und RoiuMneJlu (n Acta Onrologlca Vh>l J 19110 pagaa 35 - 49. (ICI haw mudo tracts atlon of this paper Into English jiiJ copied of Ihe trunalat Ion can he taadu available on request).
| Polyworker |
ii
High
(Autocteaner \
U yra (1953-j
(61) Autoclave
| opera tor
|
|12 yra (1961-
JUl______ L
1972-5 did
a variety of
Jobs
including PVC packing.
12 yra Very High
5 yea Medium
4 yra Lou
U r -
|Never cleaned
(Monomer
Jeutoclavea.
(operator
(See paper by
i ICHUmNO *t
120 yre -
[el Hed Lavoro
jAutoclave [Vol 6 (1961)
(operator & Ipp 555-561
(other dutlea )
|ln atiapena- 1 jion polymer- 1
(laotlon.
I
| ** lHon-eaok.tr. J Consumed jl Ittle
(alcohol. Ho (AOl..
Ned Iurn-?
|Area Rorujaai
jin eoae Deptf
I.lnc. 1975. 1
1 11
|SaR extruderf
|Commarcla] j l)ef>C 1976-
11993
1 1 1
*
i1
fs Paglla(Lungs (die* of j 7 Aug 19U)
GENC 007944
impukiai. chemical rNrmHTKrns hi,c
pKTRociiKMicAids and hlast res division
MVKK Aiigtoflarconid fayed " {Review Date; 1 Jan 1965)
Haye 15
I
COUNTRY AND t NAME or KEKEHENCE j INITIALS MO J
DATE OH
ti l KTM
| TuunJ J1
| Hurl
Ml Caul
Toucan
{no by Jap PVC Ad son)
Nagoya
KST VC POSIJKK
_L
t
DATE OH | AGE AT
DIAGNOSIS 1 DIAGNOSIS
I I -----------------T I *I
24.10.75 |
f *
----------- r
10.08.76 |
I I
TEARS OH EXPOSURE TO
DIAGNOSIS
YEARS OH EXPOSURE
DATE OH DEATH
n
HISTOLOGICAL J ESTIMATED | CONH1KHATION j EXPOSURE 1 OCCUPATION
j LEVEL |
i i
]PVC Assoc
I i
(13 yrs auto-
teaya not Iclave
fknown.
| cleaner
j4 Japan
11964 -
|Tlnee
laastgnad to
| Indicated |dlfferenc
|on 25.10.75}work since
(exposures |had 111 |ofCen at jbealcb
| 3000 ppa tip|
| Co 1974
j
[Not known Jin polyaer-
i llaatlon work i JIncluding
lautoclave
(cleaulng
J__________
15
OTHER CAREER HIONLIGHTS
16
OTHER COMMENTS
Japan Tinea 25.10.75 & Japanese PVC Assoc letter of 31.03.76
Japaneae PVC Association letter of 31.03.76
* In his letter of lat April 1962, Dr Hontesano of IAKC says Japaneae Ministry of Labour give
Date of diagnosis Age of diagnosis Years of exposure
21-00-74 52 22
007945
JKPKHlAL CHKHtCAL INDUSTRIES Pl.C PlifROOl EMI CALK AND RUSTICS DIVISION
LIVER An&tosarcoma Cases - (Review Date* l Jan I9fl5)
Page 16
11
ii
i
i(
iJ
|CuUNT(fY AND |
KtKHHEHCt
i tw
J
]i
\ \NORWAY
1 |
2 j3
11 1T NAME OK f OATH OK INITIALS f UlKTIf
i i i i
A COMPANY
| 01
| AJI
ii ti ii
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ii ii
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ii ii ii it
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5 FACTORY
6
1 r
FIRST VC EXPOSURE
fii
7)
l i
9
1r \i DATE OF | ACK AT i YEARS- Of DIAGNOSIS J DIAGNOSIS i EXPOSURE TO
i i DIAGNOSIS
)i ti
ii
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00.03.50 21.12.71 j
56
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IJ
1I
4_ 1
J
i
YEARS Of | DATE Of 1 HISTOLOGICAL EXPOSURE j DEATH r CONFIRMATION
ESTIMATED 1
i
EXPOSURE | OCCUPATION i
OTHER CAREER
| j
ii
LEVEL t
i HIGHLIGHTS i
J| 1I
iJ
J_
J
1i
1
1
other COMMENTS
ii
ii i
i
21 {04.01,72
Yea
ii
ii
!!
11 11
11
I1
t1
11
11
1 1 #t
1t
11
1 _L
J.
(Foreman 6 |Autoclave laupervlaor
i t i i i i t i i i i i J
i i t i i i i i i i i i i i i
|Confirmed by jr>r Thlla-
lEvansen of NK. |At APHE Mtg of 19 June 1976 {Mr P Ruiignua (stated that All |ha-t been a |iMiuber of a (start-up tea*. |VCrf A PVC ware (*ade Jn aaae (building. The JVCM wae aade (fro* acetylene
J
GENC 007946
'rj
imperial niKmOAi. iniwstnips' pi.c PETRIICIIEHJCAI.S ANII PLASTICS DIVISION
LIVER AnRLoe.rcoMU Caa.il - (Revliiv Hate; l Jan 1985}
Page u
CUUNTRY ANII AEKEUENCE NO
NAME UK INITIALS
HATE OK
utimi
1 I
finst ve | hath ok EXPOSURE j DIAGNOSIS
1
i
I
I
t*
U.0E.5) 1 20.10.70
--------------- I1
00.0l.A1 | 00.08.72
I I I I I I I I I I
\
I
1
j
ACE AT ) YEARS OK j YEANS OK | DATE Of I1IACNOSIS | EXPOSURE TO | EXPOSURE j DEATH
| DIACNOSIS 1
I
i II
12 [ 11 i U |
----------------------I1------------------- Ij----------------- Ip
M [ STOLOCTCAl. |ESTIMATED ]
|
CONKIKMATION |EXPOSURE| OCCUPATION |
| LEVEL
l
|
I
120.10.70
116.08.72
t
I
*1-------I Hi Eli
I I
II II
iPolywotfcer |
Ji_--_-_-_--_-_-_-_--_-_-Lr
1VCH | Jproduction |
It
II
1 1"i -------------- -------------------
"i r
J (HE
1 l
110.06.10 | Kemanord ISundavsll| 00.0i.A7
ri ;1
Ti Ir
04 Ml t s i t i i i i i i i 1 I i
116.11. L4 | Kenanord jSundava]1| 00.00,46
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| 12.01.19 f Kenumord |Sundavail| 11.05.64
1 ii
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1 ii
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1 ii
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1 ii
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1 ii
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I
i 18.01.76 i
i1
L2.05.77
t i i
22.1L .60
i
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61
i ---------------------------r~
( 29
|
1 1 | 31 1 1 |
1 1
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112.05,77 1 t1
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172.11.60 1
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11
11946-1956
i
|
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t
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i (1977 foreiaauj
i
!(19 yr,>
j
it
1
it
1
i1
1
i1
1
i1
1
i 11
Ij 1^
I I
1 KlRti -
11964-1970 |
J 6 Yeura 1 Low t 10 Ye.ru
Iceiitrlfuge |
| operator | j 1970-1960
1
|drJer
J
1
[operator
J
1i
i
I
OTHER CAHEER
HICHLICIITS
| j
|
OTHER COMMENTS
I 1----------------------
|rtr SjoelLn'e Jletter of he March 1976
Icouflnea BL
|was a woiicuter Jworker who was Iheavlly | exposed, Jprobably even
Jaoru so Chao la nuraal [reactor
[cleaner
I
i----------------------------i
1l
tin first 12 |yrs of [employment hadt Jbeen heavily Jexpossd. In |1974, liver 1 abnormalIcy |aud necrosis Jdfagnosed. (Data confirmed! (In Dr D Byren | letter 18.8.77| | to CF.HC
1 1
|Letter of
j J.i.l Nov 1981
J fro*
,
|, iPr II.vM flyrm
1
1r
1 i.
In Ills lullor of lui April 19(12, Hr Honioihmo of iahe: suya In Hwuiluii*a National Hoard oLjJS llual tli gJ vsd 20-02-70 us data of rllagiutal a for Case 0| uiiJ 15-05-77 fur Cuss 07,
GENC 007947
IMrttUAI. CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS PIVIStUN
LIVER Aiigloaarcuma Cutsea - (Review Hate: l Jan 1985)
Vt Sheer l
Page 18
COUNTRY AND
KEhiKENCK
N(J
NAME l!H f H1 PIAI.S
DATE Of BIRTH
COMPANY
PlHST VC EXPOSURE
DATE OF DIAGNOSIS
AGE AT DIAGNOSIS
YEARS OP EXPOSURE TO
DIAGNOSIS
YEARS OP EXPOSURE
DATK OP DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CARKKR HIGHLIGHTS
OTHER COMMENTS
01.J 2.72 (fox 6 Collier paper ways 21.12.72)
Barry
OU.C2.66
00.06.79
03.12.72 (Pox A Coll ler
paper
aaya 23.12.72)
1,5 24.12.74
12.10.79
SCO ppta
1944-7 VCM 1947-8 Drle 1946-61 Autoclave operator 1961-66 Drier
Lee and Harry Lancet 29-06074 pagea 1316-8
Dubioua fabrication caae
HlSh
Autoclave cleaner
Erposure llelteJ to 2.66 - 9.69
Medlu M*h
|54-5 lagging (Plant 155-6 (Drier Plant. 156-58 |Autoclave |worker 158-61 jClia rgeliand |J3rler IPlant 161-72
jForuaan \c 2/3 Plant
jPre-war ft ah
1 packer 1)919-45 .my
(vehicle |alotenance
11945-54
] f C dli packer
i i i i i i i i
i
i !
1 I
1 1
1 1
1
1 1
1
1 1
GENC 007948
1 Ml TRIAL CHEMICAL INDIFSTKIKS PLC PETKOCHKMICALS AND PLASTICS DIVISION
UK Sheet 2
LIVER AngJoearcona Cases - (Review Date: 1 Jan 19B5)
4 5l 1 2 t~t--r
1 i & i ? | a | 9 ) 10 f n
12
Jn
1
1 35
ti COUNMY AND | NAME OR | DATE OP (
reference i [NIT r AiS | BIRTH |
1 1
company | FACTORY
fiRsr vc EXPOSURE
i i ______ L
_L
1I
1
DATE OP | AGE AT
( years OP
I1 YEARS OP j DATE OP I HISTOLOGICAL | ESTIMATE!!
|
DIAGNOSIS j DIAGNOSIS | EXPOSURE TO | EXPOSURE j DEATH
CONFIRMATION j EXPOSURE | OCCUPATION |
OTHER CAREBK
NO UK
05
1 1
| JK
i| |JO.03.14 1 bp
t
1 |Barry
OS >01<51
00.10.79
I 1 1
65
i DIAGNOSIS 1
ir
I 28
|
21
1
1
119.11.79
1 LEVEL 1
1I
11951-52
| HIGHLIGHTS
11
i
ii
i
(Polycleaner
11 i1 11
11 11 11
11 11 11
11
t1
i i i i i t i i i i i
ii ii ti ii
if ii ii
ii ii
ii ii
i i i t
) ( i
i i i i
(1952-55 j Latex
11955-60 j Polyfloor
(1960-66
1 Poly |ChargeHan<I 11964-70 jCharging
(operator 11970-72
ii
t
ii
i
(Drier
i
06 (CEP
i
i 1 1931
t
I l BP
i
i (Barry
ii 1i
1962 09.01.BO t 48/9 1 18
i
12 t|1 (09.01.80
(operator
|. t
i
13 Iff a
!
|
07 |RCfl
11 11 11 11 11
[26. scan BP
i ii
t ii
t ii
i 1!
I 4.
1f
| Barry,, - 1 1963
00.00.SO 1
60
1
n
1
1
1
1
i 1
8.2 llLi..06.B0
(Poly floor
(Operator
is yfa
ICreaeer on jpoly floor
|Polycleaner
ii ii
i i
ii ii
i i
11963-5 (Recovery
OS |WM
ii ii
4l0-8.05.2C-11- BP
11 f1 1i
i ii
i ii
4.4 (Barry
t
1 19.09.50 27.ll.nt 1
57
i 1
31
i it i it
i ii
i
i
iI
1j 24 (25.12.81
1 1
1
t | mo-1958 | 500 pjtti
j1968-1974
|200 ppa
11965-1971
1
1 11950--51
(Autoclave
(operator
11951-1957
11939-1948
|Motor Mechanic 11948-1950 (Operator on
11 11 11
i i i
ii ii ii
1 1 1
IChargejidn lautoclave | bu EIJJng
|Acetylene
IfroOuctIon
|Plant
11 11 i1
i
)
i
ii ti it
1
)
f
(1957-1974 (Shift fsupervisor
11
i
ii
1
lautoclave
11 11
i
i
ii ii
1 1
JbutUIng -
|Never
11
i
ii
1
|c]eaned
tJ
i
11 11 11 11
i
i i i
11
i
11
i
11
i
1L_________________ L____i ___1L____________ _l
ii
1
ii
1
ii
1
ii
1
it
1
ii
1
ii
1
ii
1
1_________________ A _L
(autoclaves
[bat *(supervisor a | (job uncalled!
'
|onmring
fautoclave*
|ro loapuct
| tho
i J_________ 4
GENC 007949
Page 19
OTHER COMMENTS
i i
i i
i
t i
i
i i
i )
i
i
i i i
i
i i i
i
i
i i
t
i
i t
i
i
i
i i
i
i
t
i
i i
i
i
i
i
i
i
i
i
j
i
i i ti
i j
lMPKHMI fUEHJCAI. JNUUS fKJKS PLC PPHUM'IIKMICALS AND PLASTICS MV1S10N
UK Sheet 3
Page 20
I.IVER An^Lotidrcoioa Caaea - ( Review Hate: 1 Jan 1935)
1
t2
t--5--r
4
|5
COUNTRY AND j NAHE OR
HLKEKENCK | INITIALS
NU UK
_L I
09 Uicp
i DATE OK J
81 KM |
L I
COMPANY
j FACTORY J
I
07.05.25 f BP
| Barry
j
1 1
1
1
i 1 1
1 1 4L i1
10 |CJT
04.04.47 | BP
(Harry
t
1
1
1
i
i
f
i
L
1i FlkST VC EXPOSURE 15.02.50
27.04.66
7
________ DATE OK DIAGNOSIS 02.03.33
01.05.34
3 ACH AT DIAGNOSIS
S3
37
9 1 10 t ii
YEARS OK EXPOSURE TO
DIAGNOSES
YEARS OK EXPOSURE
DATE OF
DEATH
..
12 1 n i t4
HISTOLOGICAL
1 ESTIMATED I
CONFIRMATION
EXPOSURE | OCCUPATION LEVEL i 1
is r it
OTHER
i
J OTH&Jt
CAREER
J COMMENTS
-----H--I-G---H--L--I-G---H--T--S--------I ---------------------------
33
29 24.02.83
Yea
Medlua l Polyworker 2 years on
J
Acrylonitrile j
Reeln Plant. ( Alao prior to | 1950. 4 yea raj
RAF \
maintenance. |
3 yeura motor |
car paJnceliop. |
2 years la
t
Graving Dock. J
1 iI
i I
Ifl 4.2 J6.05.84 Yea Ittgli - tl [Potycleanec Heavy goods (Information
ontha (50011966-67 .
veJilcle dr 1ver(glyen In
ppia). Low--JSprny - drier ant 11 final (letter
13 laontha |bagger 1967- lllnea
(18.06.84 froa
(50 ppj. |68.
|tr H H J
Medlua -
blow down
21 aontha IstrLpper
j VI11J ana i
(iOO pp) (operator j1968-70.
i i
------------------------------ 1----------------------------
GB"'JC 007950
IMPERIAL CHEMICAL [WPJ-LTSTHIKS Pl.C PETROCHEMICALS AND PLASTICS 11 [VISION
LIVER AngLnuarcooa Caeea - (Review Daces l Jan 1985)
*UK ayatea of dates DAY - MONTH - YEAR
ITS A Sheet l
Page 21
COUNTRY ANJJ
REFERENCE
NAI1K UR INITIALS
DATE Or' BIKTII
Earl Parka
Edwci I'd Dinwiddle
Loulavllle
Loulavllle
Louis ville
lx>utsvlUe
FIRST VC EXPOSURE
DATE HE DIAGNOSIS
19.12.73 19.0(1.67
AGE AT DIAGNOSIS
I
YEARS HE l YEARS OP EXPOSURE TO | EXPOSURE
DIAGNOSIS t
UATE UP | HISTOLOGICAL DEATH | CONFIRMATION
I
t 03.03.71 J
I
27.09.71 \ (NIOSM j
uaya
I
2fl.09.71)|
_-_-_-_-_-__-_-_-_rI
19.12.73 f
I
07.01.48 | J
14
ESTIMATED J EXPOSURE \ OCCUPATION
LEVEL t
I 1------------------
i i
|Pot Cleaner |(Block Jena I 1974) p 53 ) J
13 16 I
----------------1----------------- 1
OTHER
CAREER[ HIGHLIGHTS
| OTHER
COMMENTS' j
I
|
I
History given {Rolling Stone In Annals NY |Art ACAD SCIENCES fSef l NY Acad Vol 329 (1979)|of Sc Symy
page 190 In |1974
Paper By
|A1bo Block
U A Cot tine of jjaiaa 1.7.74
OS ISA
|p 53
_______________ I______________
j Pot Cleaner
Kef Block)
l Ref 1 jAlau Block J JAMA 1.7.74 jp 53
| Pot Cleaner
Uct Block)
Louisville
|Ref 1
Courier
|Alao Block
Journal
\
02-09-80_______ j______________
jfot Cleaner |(Cf Block)
|Ref l jAlao Block
25.01.12
Ray AJBtIn
Jones?
I.Oul Bvll le
19.06.44 09.04.64
Louis ville
45
09.04.64 J
i
24.07.75 j I
JPot Cleaner |(Cf Block)
[US Air Force \ |Pot Cleaner |(Cf Block)
[Bef 1 |Alao Block
jRef l + )Loutavllie jTlmue 23.7.75 (Retired April ) 1974 }Alao Block
Char lea
r SuiurL
U3.05.22
S Otiarle- 27.08.44 uton
Goodyear Niagara
21.03.68 | t
----------- r
73.Oli.6I |
1
I He f I
I
"i-----------iKef 1
)
GENC 007951
int'KkrAi. t'm:nrcAi. fnoustk ips plc PETROCHEMICALS AND PLASTICS DIVISION
LTVKR Angiosarcoma Case a - (Review r>nte: l Jan 1985)
*IIK eyetea of date* DAY - MONTH - YEAR
USA Sheet 2
Page 22
COUNTRY AND
REFERENCE
NO
* -------------- 1-------------
NAME OR | DATE OF INITIALS J BIRTH
I
piHsr vc EXPOSURE
DATE OP DIAGNOSIS
ACE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OP EXPOSURE
OATE OP DEATH
UISTOLOCICAL | ESTIMATED J
|
CONFIRNATION j EXPOSURE | OCCUPATION [
j LEVEL l
j
OTHER CAREER
HIGHLIGHTS
( j
j
OTHER COMMENTS
Raynond
CettleFlngerT
I
|08.U.3t
I I
Louis ville
1------------116.08.13 Goodyear Nlugura
I I ] 2000 ppa
)
I I I
I I
|Ref 1 had |wrung figures |re flret
| exposure.
jLoutavl He
iTluca (29.10.74, 112.3.75,
|JO.3.76
|Ref l
J27.05.09 Goodyear Niagara
16.01.70
J Ref L
Pcaitcld a in.
KitcliUitn I
t
I
I
I I
I
I 1-------------
tficlidrd Edward
JOl.J2.2L
I
CJ ended 11
Pottetown 11.07.49 Pa
S Charle ston
07.04.74
|Htgh |f> yraJlO jrra aa jtttillty &
|ReE t 4- letter
j (reactor op. |Service op. (of 26 April
J
((not cleaner(Bagger
[1978 I roe
]
j- separate jDryur op.
(Rueeel) A Park
] (crew cleaned[Stripping op. |to J T Seawe11
| [autoclaved) J3 yre prior |uf HCA
(f
Jeervice in
]
([
(tyre plant
|
J________ l_________ !__________ l_________
12000 ppa
i i
l
i i
[Charleston (Daily Hall 121.7.75
|Never dlagJnoved aa anglioaarcoaa of |llver. In form ation given Jn |latter 22 Hay |J984 frue JJ A Slg.
____ L________I___
GENc 007952
|AccounLantj |ASI. - No ev idence of VCH luxpnetiru. j Information
rFam'J TAVEitlg", aa above.
IHPCUlAL iMIl'Ki l'AL JNDHSIKfKS I'LC PKTNnCNFrtTCALS AND PLASTICS III VISION
LIVER AngIoaarcoaa Case* - (Review Date: l Jan 1985)
* UK Syetea at dates PAY - MONTH - YEAR
USA Sheet 3
Pa^e 21
1 i1
i 12
t t3
( 11 1 Ii jcourjiKY AND | NAKh OK | PATH Of
j REKEKENCK | INITIALS | B 1H I'JI
| NO
i
i
i "I--
i 1--
| USA
i
i
|i i
4 15
6
)1 11
t 1 EIHST VC S'OMI'ANY 1 FACTOKY | EX I'USUKE
11
11 n------------------ r
1t
|i i
i ii
7 a i 9 i 10 i ii t 12 i n 1 14
1i 1i
Jt 11
DATE Of | ACK AT i YEARS OP DIAGNOSIS j DIAGNOSIS i EXPOSURE TO
YEARS OK | DATE OP EXPOSURE | DEATH
|HrSTOLOGtrAi | ESTIMATED
CONFIRMATION EXPOSURE | OCCUPATION
i i diagnosis
i
t LEVEL
|i 1i
i1 li
1 1
ii
i
15
OTHER CAREER HIGHLIGHTS
t i
[1
| | 1 1 1
1
it
OTIIKB COMMENTS
1 16 | ,)jhhj n 104.11.27 B EC
ll.oula- | 0B.fl5.50 00.00.69 1
41
i
19
llloward
|
i i
|vllie i
( i
ti ti
ii
ii
ii
ii
ii
ii
ii
ii
ii
ii
ii
ii
( 11
TT
ii [Loeta- |
iI ii
1 l? | PeereulHioik |06.05.11 &f11
jvllle
| 23.06.55 11.10.74 j
41
t
19
i| t
i i i
ii
ii
ii
ii
ii
i
t
i
ti
ii
ii
ti 11
1i 1i
ii 1i
1 18 |Chari le |22.04.2a EEC
lArLhur
1
(Avon .Lake| 15.09.54 00.00.75 \
46
i
2
)"
i
ii
i1
ii
ii
i1
ii
ii
i1 i1
i i sii
it
it
it
ii
ii
x1
1i
J
19
(VlrtiU
(00.00,IS ucn
jcilf l 9 11 dll 1
t1
_jj. 1i
iI
ri
|S Charle-| 00.00.43 19.06.75 1
60
i
32
| aton J
ii
ii
ii
11
ii
ii
11
ii
ii
11
ii
ii
1 1
| 20 1
L tj
ii
1r
ii
1!
til.OB.J7 Goodyear |H!agara J 00.00.65 30.01.76 |
58
i
21
ii
1L
11
j 21 | |Chester
02.09.09 UCC
|ltt iik le
i
ii
ii
ii
L Ii i
[I I|S Charle-j 00.l2.4t Burly 77
67 i 30
|j ston
ii
1i
1i 1(
L
i i
i
.J___
i t
t
L
i
i
i
__L
t
i
i
I
04 127.03.69
Yen
i
i
i
i
i
i
II 1 1 Yea
L9 116,10.00 ota 11.10.74
i but lid i poat-oorieu i 16.10.60
i
I1 11
| J951-4 17CH Ipolynerliaatlon
i 1
1 1
Fro* 1954
(Table 4 In
onward* In
(Wagoner
Amy aaad other (Test Jtaony to
service.
(US Senate
46-50 Amy
(Conflrued In
|H N Jo la ii a on ilec 07.08.78
I 1
[Dr H N Johnsonj [letter of (24.2.01 conjfirmed death
|6 year* after IdJaKnoata 1
n (02.U.75
i
i i i i
i
i1 1i
32 106.04.76
i i
i
i
j
T
18
i i 1 110.01.76
i
1 11
1 11
22 102.01.77
i
i
i
i
j
Yea
Yea Yea Yea
113 yra
|Navy
Inutocleaner]
|8 yra on
lEatol
jTyre Store
IpEaatlclaer(
|6 Carboaet
(operation
1 i
(2000 ppa
!
1 | 1
(Con f trued 1n (M N Johnson |Ur 07.na.78 (Mao Rolling JStone oag 115.01.76
i 1 i
|U11llaaeport |Sun Gazette 121 June 1975 (Chartuecon 1)1.11/ Mall (21.7.75 Ii
|N[OSH letter jof 25.10.79
1 i
[28 yra wl tli
lute .t SC
j Ret 1 red
|Nuwa reteawu
123.2.77
J
l J 1
GENC 007953
JMl'lCK | A I, CHEMICAL INDUSTR IKS I'l.C pei'HOCtlKMICAl.S AND ELASTICS DIVISION
LIVKTt Aug luuarcomj C.iues - (Review flatei 1 Jan 19H5)
*INC ayateu of datea DAY - MONTH - YEA*
USA Sheet 4
Page 24
13
COUNTRY AND REFERENCE NO
NAME OH INITIALS
HATE OX BIRTH
USA
COMPANY
FIRST VC EXPOSURE
OATH OP DIAGNOSIS
ACE AT DIAGNOSIS
YEARS OP EXPOSURE TO
DIAGNOSIS
YEARS OP (EXPOSURE
DATE OF DEATH
ursmncrcAL | estimated CONPIKHATION ( EXPOSURE
1 1 LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
OTHER COMMENTS
02.10.21
Loil ( d* ville
OO.fU.76
"11"
rrki u rl ea EJwuiJ Moure
00.00.21 1lTT..( onr
Great American Cheialcnl Company__ UCC
Fitchburg Hues
S Charleaton
a. 09.50 T9HT
rrM'.rr
"Sir
(25)
R XniaJnaH let er of 5 Novt aiber 19H0
U 06.04.71
Yea
l.outavl lie Tines 26 . L.76 said he waa the 10th AS vlctLa at Bella l.ane of whoa 0 haj died by 26.1.76 In lila letter of 16.09.ft) Dr H N Jo 11 ue oi couflrare th(u la the caae Jeacrlbei by Dunn a her Teaburro 4 Yea In Feh I960 Aa J Medicine VqI 70 n2SO
2Tf (NIOSEl eeya 26)
irasr?r
Chaiungloaarcoaa (t Kanlnakl
26/2/79)
|HedInn to
jhigli for |24 jra
i i i i i i i i
i j t i i I i
i t i i i j
11941*65 non -|l9l)- v.t (N M Wheeler
|aolvent
(off and on
lletcer of
Jvinyl reeln (labourer
I18.E.77 to
|unlt and
11919-4! any (J Stafford
[dJaparalon |1ave been
llflvee detalle
Jvinyl reeJnafexpoeed ae
|Roae Kualnakl
(unit flret Ireactor |aa fitter | cleaner
Jletter of
\unm
(helper, Chen(1942 becaae |R Kaatnakl
Jelil ft
(ahlft fitter |(5 Nov 19fl0)
|utl11ty *an 11946 bdCdae Jsuggest* Diet
i lehlft utility )N10Sfl will
i
|*a si
|retaln on
t
| 26.G4.65
(register wince
i |eaployuent wa i|thle neoplaea
i
| tonal nut ed
|nay be aueort-
11
i p.----------
(ated wltli ASL. |r N Utieeler
t | letter of
i (2Q/2/79 and
i1 4
|Roeu KanJouRL | let Lera of (26/2/79 end
C n n -j^
IVll/dii
im-KKiAi. crut-mCAE, [ndifstiues ijt.c.
purunnjt-Ni^At.s and plastics division
LIVER Angloaarcoeia Cases - (Review Date: 1 Jan 19J3-5)
*LTK eystea of dates i>Air - month - year
MSA Sheet 5
Page 25
ii
I
I
i
| COUNTRY ' N | m'KHDNCF
j HAUK
| KAHK OH j INITJAI.S
DATE Of ( ' BIRTK | COMPAHf ( FACTOR T
first vc|Sate of EXPOSURE | DIAGNOSIS
I | USA
i
'il_____ |
l |JoltLt I
1_______ ------------------- 1----------
I flurry 07.07.23 J BFG
I
I ________
|Louiej vllie
1
T""........
I 03.10.47 j 00.00.77
| fki|i to 2
| years
I after
I death)
I
I I
I
I I
I
t
i
Ifm rest
ii.05.Tt i occ
|s I uton
01.07.61 | 10.11.78 t
I I(
t
t t
I
ii,nt.i7 | ucc
( (S Charle- 00.08.66 | 03.11.78
I
I 12.10.07 fllCC
I atoo
rI
(S Charle- 00.05.62 | 00.03.a0
( | scon (
I I
22.07.22 ] Tenneco
I iFlemlngton 11.06.66 | 10.12.80
| Chemical a l I I
I I t
I(
II II
oa.n .23Tucc
I l3 Charle- L2.I)57TT1 01 .08.81
t ( stun
I
iI
iI
iI
iI
iI
iI
iI
iI
iI
iI
iI iI iI
i
ACR AT I) [ACNOS IK
!m
n11 f 12 I
I J4 I 15 I
YEARS OF f YEARS OF EXPOSURE TO j EXPOSURE
DIAGNOSIS
DATR (if [ JIISTOLOCICAI. [ ESTIMATED \
\
IJRATII j CONFIRMATION | EXPOSURE j OCCUPATION j
OTHER[
CAREER
|
____________ I___________________ j t.F.VEL j
j HTfillLICItTS j
CITHER COMMENTS
52 (death)
28 (death)
37
I | ]B |
I i ) i t i i i i i i i
i 11.02.75 [
I 1
I
I 20 ((NKI.SII jaaya 27 land C I Dally Kail |25)
I
oi.ii.7B rI______________
I I
oTToOfTT
I I
57 j JT t I
d2.06.82
t 60*C
I
II
I
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jaoaa 8egrea(ln FVC
|
I
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fto 22
jplanta fro* j
(cheialcala |cald roau tr>|
(but main (paat*
|
(aapoaute Jrenovary to |
|uaa to VCH.|PVC charglngl
Iprnbahly (operator to J
ll.lgl.
|pad te
I fcbnrgl ng.
(ILL Augnat
(1965.
126/2/79 and (Prof. Tambnrro llattnr of (9/1/79
I I
High
(Tonal nated
leeployuent Ian 1966
I
(Operator tonErpoaure In JR N Wheeler
(10,10.76
|bulk and
11Cr of 4 Jan
| Idlaperelon PVCJ1979 and
|
loanufactnra
]Charleston
II I1 II
(Dally Hall J30.il.78 and jW KaaI nek [
126/2/79
Kaalnskl
JletLer of
J6/4/79 (R Kanlnnkl
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i (6 yr*
(Lottery of 119th .Inna 1980 |t Stl. Han 1980
|
(Elsewhere
I
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|Boller IwsueeJ
| Operator j9yra.
]
(
|lJl|(h (But JChmiJcal
"1 Proa 1959 "to [Dr flecey
|not aa lit ghfOperator In (1976 Allphattc|letter
]ee reactor (charge
IChealcala
Il6.l0.fll end
(cleaner
|reactor
Joperator and JR N Uheoler
|would
J
jfrou .July 1976Jlet(er of
(experience)|
|toJute
|9.JIaflla
| forked as (
jEorctuan
|Al*u Ur Uauey
| labourer Ifrots
( |
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| June 1941 |
|0pumtJon
|date of Jedtli.
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J
i
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|
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|
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| J
Mirui.il. <:in:hh:ii. industries limited plastics division
LIVER Auk I odd r coma Cases (Review Ddte: l Jan I9R5)
USA Sheet 6
*UK system of date DAY - MONTH - YEAR
Puge 26
ii ii[i
i! 1 1
auiNiKr Atm | NAHE OR | DATE OR reference j INITIALS | BIRTH
4 .
COMPANY
i |s
6
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NO US 32
ii ii 1i |C W Cl rouxj 22-02-00
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7 NATE OF DIAGNOSIS 00-07-79
l L--05--13 2 03-11-02 16-07-03 21-Ofl-fll
8 ACE AT DIAGNOSIS
7t
54 48 71 50
9 1 io
YEARS OF | YEARS OF exposure ro j EXPOSURE
DIAGNOSIS 28 j 14 Win PVC | autoclave |a rea)
2H [ 20
27 | 10
39 1 14
27 { 27
il DATE OF
DEATH
17-05-80
U
HTSTOLOCICAL CONFIRMATION
An aotopay was done and
Ii
i
n i i4 i 15 1 14
1 1
ESTIMATE l> |
]EXPOSURE |LEVEL
OCCUPATION
1 i
i
i
i
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1
~1--------------I 0TIILH
CAREER
j COMMENTS
HIGHLIGHTS i
The death
1 1
|1940-1951
1 W
i
l 1 | Information
cert 1 fleece|Various jobe|
(given In
Immediate cause of death given
Rave
Mr Giroux* usual
|n polymer
(manufacture jailTVAR
i i i
(letter of 24 jFebruary 1962
|frum Dr
aa
occupation |LUSTKEX
i
(Walter C
"AnRioadrcoma" aa "kettle|1951-1964 i
JBarnes of
operator" {Various Jobaf
|Monsanto
In
|ln and
i
ISprlngf(eld co|
"chemicals |around PVC i
|0r A Hunn of
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jNonaanto
|1964-1973 i
(Europe.
JVarious
i
i
(clerical
i
jjoba In PVC i
i i
(polymerisation
i
[facility/ i
t
|Retired
i
i
----------------------- [I0-1----H---3-----7--3--.----- 1 IT
1
1
A1 Ive
Yea
(Multiple
j Job.
1 1
(Prof Tuaburro (letter of
|(ncludIng 1
U2 A.is 1982 +
(Poly
1
(Dr M N Juhneonf
(Operator + 1
llecter of
iPolycleanor. |
----------------------- 1
T~
128 Feb 196j.
1
O4.OS.03 Yea
IPoiy
J1965 left BFG | Dr 11 N Johnson |
(Operator + |to become a Jletter of
/Autoclave jClergyaan.
13 Nuv 1982,
(Cleaner
i
138 feb 1983
11955-65.
i
land 9 Aug
16-07-63 Yea
A1 ive
Yea
ii
11
IIIr)i from f
1944 to
|
1
i
1955.
|
i
Medium from|
i
1955--1956
i
I------------- '1
(loderata
L 956-56
i
(labourer
11984.
r
|Dr Decay
(letter of is Sept 1981.
1
t T
(R H Laumlrle
| letter of
11956-57
j
i(prod helper
(1957-70
i
|opc rator
i
(1970-75
i
112 Sept 1983 /spotted at Imedlcal |H.y 1983,
jTuatliiK
(elect rlctaii i
}J1975-present
(operator
i
/commenced jMuy 1983
t
GENC 0079 =u
I 1_-------------------------
1
MPl'H/AI. tilth HI GAL INDUSTRIES LIHITPI) PLASTICS DIVISION
LIVER Ann losdi'oojnj Ciaes - (Review Hate: l Ian 1985)
USA Sheet 7
L]K uyateei of dace HAY - MONTH - YSAR
Paye 27
COUNTRY AND KEPEUENCE NO
NAME UK INITIALS
HATH OP JilflTH
Hr J PayLoo
i 5I6
7
| F1KST VC l'ACTOAr i EXPOSUKd
I
_____________I_____________
!
Louie- J 1051
(Ilia
|
I
I
I
I
I
I
--------- I----------
OATH DP DIAGNOSIS
06.08.84
8 ACE AT DIAGNOSIS
54
9
YEARS OP EXPOSURE TO
DIAGNOSIS
31
i 10 t
1
nrycabs
1 |
ornsiHtti j
1
n
DATE OP DEATH
i^
12 13 1 14 1
____________________ 1 *
I 1
1 1
HISTOLOGICAL ESTIMATED 1
1
CONP7II NATION EXPOSURE | OCCllHATinN |
1LEVEL
i
22 *06.08.84
Yea
i i
High
{Worked |regularly In IPVC area. {In die early {da ye waa a |reaccor |cleaner 1)053-75.
I 15 I 16
OTHER CAREER RICIJ LIGHTS
| OTHKH j COHHKNTS
I I 'I -----------------------
[Inforadtlon |glv#n In lletter J09.08.84 fro* jDr H N Johnson f I I
Hi )B
I-IUB
llB.ua. It |Alr
I I |Pr<nliirta
I II til
I II
I II I II
I II
I I1 III
I II
III III III
III
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II
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10
I 10 I2H.L0.83
|| tI II II II II l| II lj II |) II || t| II II II I) l| II II II II II II II II II l| ||
I
I I
High 1963-1982
iNon.al proIgreaalon |Fro*e helper |co eonlor
loperatur.
{cleaned
{reactor..
I .tripping
land recovery lareae a. I well aa
Icharglug
loperator.
I
I
[
I
I
I
I
I I
I
I
I
I l I I I
I I I I _______________
|Th roNtuj Icytopenle and 11 euVopcii 1 a jalnca 1978.
[Cold treatment Jfor arthrlile Jim. UnJur jDr*a care |about 6 aonths J before death*, |had paaJ |a LandsrJ JphydJcdt ejeun(Inadon 2 laontha |eurlter. JJ barr letter jof 22.10.84.
i i i i i i i i i i i i i iL it
L (-
IHri KfAL fTJII'H f TAf. INNUSTKIKS Pl.C I'liiKOUIKH 1 CALS AN PLASTICS HIVISION
LIVER Anglnaarcoua Cases - (Review [Vate; 1 Jan 1964)
Page 2B
COUNTRY ANO
RfiFKKfiNGl'
MCI
NAHE OK C MXT TALS
J>ATE Of fllRTIf
YUGOSIAVlA
Jugo Vtull
Jugo Vinll
Jugo Vinll
Jugo Viol L
Spite Spit t Split
Split
FIRST VC EX POSEIRtt
HAT* 0/
DIAGNOSIS
ACM AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF
EXPOSURE
OATS OF OK ATI I
HISTOLOGIC At. CONFIRMATION
KSTIHATRll EXPOSURE
LEVEL
23 t).01.76
01.09.76
03.09.76
VCH Product Ion
VCH Project Ion
OTHER CAREER
HIGHLIGHTS
| j
|
OTHER COMMENTS
1 I
(SARIC eC el {paper |Rnv Health |Perspective |Vol 17, |pp 169-192 |1976
|*Jii hla letter jof 3 Oct 1976,
{Dr Spirtus of INIOSII changed [the status of jcaae U2 to VCM
JpruJuctlon feiapl oyee. jllr Splrtas
(also notified {a new Case 01 lalso a VCM
(production
(worker
|Roc Kanlnskl jLetter of
|I9th June I960 jend IARC
(letter of jl April 1962
I I
GENC 0Ci??5g
TABLE 1
(Review Date - 1 Jan 1985)
Incidence of ASL Cases Per Annum
By date of death
1955 6 7 8 9
1960
1
2 3
4
5 6 7 8 9 1970
1
2 3 4 5 6 7 8 9 1980
1
2 3 4
N.B.
1Does not
Total
1
0
1
0
0
0
1
1
0 2 0 1 1 5 3 2 3 5 7 6 ' 11 11 9 10 5
10
4
1
7 __ 3 109
include Italian 01 but does include German 03.
vc 00?
2 The 1977 total includes US case 24which is a Cholanglosarcoma.
3 The 1982 total does not include US 33 who is ^^Ure and F 15 who is alive. 4 The 1983 total does not include US 36 who is aljRe.
Distribution of ASL Cases by Country
USA W Germany France Canada UK Sweden Yugoslavia Italy Czechoslovakia Japan Belgium Norway
35 *** 21 ** 17 *** 10
9 5 **** 4 ***** 4* 2 2 2 1
TABLE 2
(Review Hate - 1 Jan 1985)
Page 30
Total
112
* Omit ItOl - atypical case of PVC bag extruder. ** Includes GE03 aerosol can filler.
*** Includes case US 24 which was diagnosed as Cholangiosarcoma;& US 33, and 36; and F 15, who are alive. **** Includes one monomer worker. ***** Includes two monomer workers.
i.e Western Europe North America Rest of World
59 45
8
--
Total 112
SENC 0q?960
Pattern of ASL Cases by Factory (a) W Europe
TABLE 3
(Review Date - 1 Jan 1985)
Of the 59 cases in W Europe, 49 have occurred in clusters at 11 factories. Of the 21 German cases, 18 have occurred in clusters at 4 factories.
ASL Cases
Dynamit, Troisdorf Chloe Chimle (Formerly RP), St Fons BP, Barry Kemanord, Sundsvall PCUK, Brignoud Wacker, Burghausen CWH, Marl ICI, Hillhouse Solvay, Tavaux Lonza, Haldshut Solvay, Jemeppe
10 8 7 5 5 4 2 2 2 2 2
49
Page 31
NB: There are 31 pre 1962 PVC plants in W Europe; 18 of these have had ASL cases (Ref. Table 8) (b) N America
Of the 45 cases in N America, 38 have occurred at four factories out of a total of 49 factories - in M America 38 plants have not had ASL cases.
BFG, Shawinigan BFG, Louisville UCC, S Charleston Coodyear, Niagara
ASL Cases
10 14 10
4
38
GENC 007961
NB: There are 29 pre 1962 PVC plants in N America; 11 of these have had ASL cases (Ref Tables 9 & 10) (c) Rest of World
The 8 ASL cases are believed to be In 1 cluster of
rd 2 clusters of 2 cases.
TABLE 4A Latency Periods (Years from first Exposure to Diagnosis)
(Review Date - 1 Jan 1985)
Page 32
Country
No of Cases
Total Years
Average
W Europe
Belgium
2 35 17.5
France
17 438 25.76
Germany
21 385 18.3
Italy Norway
4 74 18.5 1 22 22
Sweden
5 122 24.5
N America
UK
9 207 23.0 59 1283 21.75
US 35 885 25.29
Rest of World
Canada
10 45 '
204 1089
20.4 24.2
Czechoslovakia Japan
2 2
30 15.0 39 19.5
Summary
Yugoslavia
4 8
85 21.2 154 19.2
W Europe N America Rest of World
59
45
8 112
1283
1089
154 2526
21.75
24.2
19.2 22.55
SENC 0079^2
* Of the countries with 10 cases, France and USA have average latency period above world average and Germany well below
DISTRIBUTION OF LATENCY PERIODS TABLE 4B
(Review Dace - 1 Jan 1985)
Page 33
1I 1 i 1 1 I1
11 1 i 1 1 11 1 o- 9 yrs | 10--14 yrs | 15-19 yrs ! 20-24 yrs | 25-29 yrs [ 30-34 yrs | 35+ yrs |
11 ! 1 1 1 11
11 1 1 1 1 11
11 1 1 1 1 11
Belgium
|
1
1 21
1
1
11
1 iJ 11 j I t | 1
Canada
| i1
1 31 11 l[
1 5t 2 1 ([ 11 1
1t 1f
Czechoslovakia |
1 1| 1[
i
1
11
tf j 11 11 i1 j1 ] 1 11
France
)
1
1|
4I
21
51
2|
31
j 1| i1 I 1 l[ i 1 11
Germany
| 11
t 4 1 9 1 6* | 2 i I\ 1i ii fi 11
ii ii 1l
Italy
t1
i 2I 21
1
fi
[1 [ | 1 1 fi
Japan Norway Sweden
UK
USA Yugoslavia
TOTAL
|1 11 11
1 ii
1 \ r" i
1 1I
l
|1 if 11
i i
[11 f1 11
i ii
| 1 21
iJ I1
I
]1
i
it
i
i]
i
|11
ii i
11
i
1| 1
1 11 21 l1 31 11 81 l
E i
i
i
32 !
1
1| J1
1| 1
i
1 r1
i i1 7] i
r
41
1
1 28 [
1
i ij i i1 2l ii 31 i1 81
i i
i
i
22 1
1
f ii i ii
il
ii 2|
|1 3|
1 i
i
i
10 I
1
1 \l
i
11
i
i1
i
f1 5|
i
i
i
i
8I
1
1
Total j
1 1 1 2I |
10 1 11
21 t1
17 | i
21 1 ii
4I |
21 11
1| 11
5|
1 91
11 35 |
i
41
1 1 112 |
1
Average Latency Period
17.5 20.4 15.0 25.76 18.3 18.5 19.5 22 24.5 23 25.29 21.2
22.55
* Includes C 03 aerosol can filler
GENIC 007963
(Review date 1 January 1985)
Page 34
TABLE 4C
LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE
MAX POSSIBLE |
YEAR OF
1
LATENCY PERIOD 1 FIRST EXPOSURE 1
LATENCY PERIOD
| ARITHMETIC MEAN
1
1 OF LATENCY PERIODS 1
1 11
44
| 1939
1 38*
43
1 1940
1
I1
1
244 =. 34.86
1
42 1 1 1 37,21,37,41
|7
1
41 1 2 1 32,38
|
1
40 1 3 1 38,14,32
|
I
1
4
1 28,11,24,20,24,34,39 |
718 = 26.59 1
i 5 1 27,22,28,29
) 27
1
1 6 1 21,29,31,26,28,15,23,1
1
1
1 30,35***
|
1
36 1 7 1 29,24,29,28
|
1
35 1 8 1 28,24,34
|
1
1 9 1 30,26,20
| 458 = 24.11 1
1 1950
1 26,22,31,19,23,14,33 I
19
1
| 1 1 19,28,17,28
|
1
31 1 2 1 21**,15
1
1
30
1
3
1 25,22,23,22,20,31
|
1
1 4 1 21,21,25,25,21,28***,I
1
1 1 22
| 623
21.48 1
1
5
1 22,23,24,14,19,21,27 I
29
1
1 I 27*** I
]
1 6 1 21,12,27***
|
1
25 | 7 1 19,17,15,13,16 |
1
25 1 8 1 18,18,15,17,20 I
1
1 9 1 16,21
| 345 = 16.43 1
| 1960
1 13,18
| 21
1
1 1 1 15,16,16,16,19,18,12 1
1
21 1 2 1 13,18,17,12,17 |
1
20 1 3 I 16,17,19
|
1
1 4 1 16,17
| 139 = 15.44 1
| 5 1 11
19
1
1 6 1 9,18
|
1
16 1 7 1 16
1
1
15 1 8 1
1
19 1 1970
1 1
1 11 11 1 2 1
10 1 3 1
1 41
1 TOTAL
1 112
11
11
1 1 VIOLA
11
1
1 1 MALTONI
1 1 GOODRICH
I 2527 = 22.56 1
1 112
1
* Cholangiosarcoma ** Aerosol can filler *** US33 and 36; and F15 still alive.
PJST80061400,11/WPX7-2
(Review dace 1 January 1985)
Page 35
TABLE 4d
LATENCY PERIODS OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND GEOGRAPHICAL LOCATION
MAX POSSIBLE . T
YEAR OF
I
LATENCY PERIOD 1 FIRST EXPOSURE | 11
44 1 43 1
1939 1940
1 1
42 1
11
41 1
21
40 1
3I
1 4I
1 5I 1 6I
36 1
7I
35 1
81
1 9|
1
1950
1
1 1I
31 1
21
30 1
3I
1 4| 1 5I
1 61
26 1
7|
25 1
81
1 91
1
1960
I
1 21 1
1I 2I
20 1
31
1 4l
1 51
1 61
16 1 15 1
71 81
19
1 VIOLA 1970 11 1
11
1 21
1 MALTONI 1 TOTAL
3
I
LATENCY PERIODS IN
WESTERN EUROPE |
NORTH AMERICA
1 38*
37,41
38 28 27 21,29,31,33 29 28,34 30,26 26,22,31 19,28 21** 25,22 21,21,25,25 22,23,24,27*** 21,12 19,17,15,13 18,18 16,21 13,18 15,16,16,16,19,18 13,18,17,17 16,17 16 11 9,18 16
1 21,37 I 32,38 1 14,32 1 11,24,20,24,34 ;39 1 22,28,29 1 26,28,15,23,30,35*** I 24,29,28 1 24 I 20 1 19 1 17,28 1 15 1 23,31 | 21,28*** | 14,19,21,27 | 27***
1 15
1 12 1 12 1 19 I 17
59 * 1 45
1
1 ROW I
11
11
II
11
11
11
11
1I
11
11
11
11 1 23,14 1
11
11
1 22,20 1
1 22
1
11
1i
1 16
1
1 17,20 1
11
I1 | 11
1
1
1
1
1
1
1
1
1 11
1
1
18
* Cholangiosarcoma ** Aerosol can filler *** US33 and 36; and F15 still alive
PJST80061400,12/WPX7-2
GENC 007965
(Review date 1 January 1985)
TABLE 4E
PLANT LOUISVILLE
11 1 START 1
LATENCY PERIODS OF ASL CASES
I UP
1
1 DATE 1
I1
11 | 1940? 1 12,14,15,19,19,20,24,27,28,28,28,29,29
1 1 31 |
SHAWINIGAN
| 1941? 1 11,12,14,21,22,23,24,24,26,28 |
S CHARLESTON 1 1939? 1 24,30,32,32,34,35,37,38,38,39 |1
TROISDORF
1 1954 1 12,13,16,16,17,18,19,21,23,25
11
Page 36
1
NO OF |
AVERAGE
CASES | LATENCY PERIOD
1
1
1 14 |
23.07
1
10 |
20.5
10 |
1 10 |
1
33.9 18
PJST80061400, 13/WFX7-2
(Review date 1 January 1985)
Page 37
TABLE 4F
LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT
YEAR OF FIRST | "I 1 1
EXPOSURE
I S CHARLESTON | LOUISVILLE I SHAWTNIGAN I TROISDORF
1939
| 38
1
1
1
1940
1
11 1
1 1 37
1
1 21
1
2 I 32,38
1
1
1
3 ! 32
1
I 14
1
4
1 24,34,39
I 20
1 11,24
1
5!
1 28,29 ;27 | 22
1
6 1 30,35
1
1 26,28
1
71
I 29,28
1 24
1
81
1 24
1
1
91
11 1
1950
1
1 19
1
1
11
11
1
21
1 15
1
I
31
1 31
| 23
1
4I
1 28
1
1 21,25
51
1 14,19
1
! 23
61
I1
1 12
71
11
1 13
81
11 1
9 11 t
1960
1
11 1
11
1
1 12
1 16,16,19,18,
21
| 12
1
1 17
PJST80061400.14/WPX7-2
(Review date 1 January 1985)
Page 38
TABLE 4G
PLANT
i START-UP DATE 1 LATENCY-PERIOD OF ASL CASES | NO OF I AVERAGE PERIOD
11
1 CASES 1
11
1
SUNDSVALL | |
1945
I 16,19,27,29,31 1
1 5 | 24.4 years |1 1
BRIGNOUD ST FONS BARRY
| I1
| 1i
| 1
1950 1939 1948
I 11,16,18,26,30 i1 I 21,28,29,37,38,27,41,35
( I 9,17,18,28*31,33,18 i1
| 5 1 20.2 11 i 1 8 1 31.88 11 I 7 | 22
I1
BURGHAUSEN |
il
NIAGARA
I
1933 1947
I 17,21,22,25 11 1 15,17,21,23
1 4 1 21.25
11 1 4 I 19
SPLIT
1941
20,20,22,23
21.25
PJST80061400,15/WPX7-2
GENC 007968
(Review dace 1 January 1985)
Page 39
TABLE 4H
LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT
JS/JH/DSO 16 2 January 1985 PJST80061400,16/WPX7-2
GEHC 007**''
TABI.E 5
(Review Date - 1 Jan 1985)
Page 40
Annual Incidence of ASL Cases (Date of Death) by Geographical Area
1955 7
1961 2 4 7 8 9
1970 1 2 3 4 5 6 7 8 9
1980 1 2
1983 1984 TOTAL
1 1 11 | Western Europe | North America | Rest of World | Annual Total
1 i 1 1 1 t |1
1 |1 |1 I1 14
1 il tl il il 1l
i i5 12
!1 12 11
11 1 11 I 11 1 11 1 11 1 7i2 1 11 1 15 1 13 1 12 j1 f1- 3
5
| 1 14 1 3|8
1 3 12 1 -|5
1 6 I 4 1 1 1 11
i 6 1 3 ! 2 | 11
f ,6
13
f
t9
| 7 1 2 1 1 1 10
I5
- 1 "1 5
1 8 1 4 1 ~ 1 10 i 4 i0 i -| 4
1o
11
I nil to date j
1
14
t3
| nil to date |
7
12
11
1 nil to date |
3
j
58* **
1
43**
1
8
1 109
Cumulative |
|
Total
1 Key Events |
1 11 21 31 41 61
71 12 i 15 1
17 | Viola
1 1 1 1 1 1
1 1 1 |
20 1
1
25 1
1
33
| Haltoni
t
38
| Goodrich
|
49 -------------1------------------------------- 1
60 1 69 1 79 1 84
1 1 1
94 1 98 1 99 1
106 I 109
I ! 1 I
* Includes G03 aerosol can filler but omits It 01 bag extruder
** Does not include US33, and 36; and F 15.
All still alive
(Review date 1 January 1985)
Page 41
TABLE 6
ASL CASE NUMBERS BY YEAR OF DEATH AND GEOGRAPHICAL LOCATIONS (EXCLUDING 1T01)
1 KEY 1
1i
I EVENTS 1 1
1 WESTERN EUROPE
| NORTH AMERICA
1
i REST OF WORLD i
1
11
1955 A
1 111 Cl
ii i
17 18
1 C2 i 1i
19
1i
1 1960
1i
11 12
I US8
I C3
i i
13
1i
14
I US5
i Cz2
15
1i
16
i
1 7 1 FI 18
1
1 C4,C5,US4,US7,US10
i i
1 9 1 G1
1 US12.US16
i
I Viola
1 1970 11 12
I Swl I G2 1 N1,Sw2,UK1,It2
i US11 "1 C6.US2
1 C7
i i i
IMaltoni 1
3 I G3**
1 C8.US1.US3.US23
i Yl,Y2,Czl
I Goodrich 1
4 I G4.G5.UK3
1 C9.US13
i
1 5 1 F2,F3,G6,G7.G8,It3
I US6.US9.US18.US26
i Japl
1 6 1 Bl,F4,F5,F6,F7,Sw3
I US19.US20.US22,
i Jap2,Y3
1 7 1 F8,F9,G10,G11,G12,Sw4 I C10.US21.US24*
1 8 1 F10.F11,G9,G13,G15
1 US27.US28
i i Y4
1 I G16.G17
1
i
1 9 1 FI2,FI3,UK4,UK5,G18
1
i
I 1980 - 1 UK6, UK7.G19.Sw5.G20.G21 I US17, US29, US30, US32
1 1 1 It4,F14,UK8,G22 !2
1
I US31
1 1
1 3 1 UK09, It5, FI 7, B2
1 US35, US34, US38
1
1 4 1 UK10, F16 1 Total r~58 ***
11
I US37
] 43*** 1
1 18 1
* Cholangiosarcoma ** Aerosol can filler *** Does not include US33, and 36; and F15.
All still alive.
HEPD PJST80061400.1/WPX7-2
6ENC 007971
(Review data 1 January 1985)
Page 42
TABLE 7
ASL CASE NUMBERS BY YEAR OF FIRST EXPOSURE AND GEOGRAPHICAL LOCATION (EXCLUDING IT01)
KEY |
1-------------------------------------- -------(-------------------------------------------------- 1------------------
EVENTS |
I WESTERN EUROPE
I NORTH AMERICA
I REST OF WORLD|
11
1
1
11
1
1
1 1939
| US24*
1
1 40 I 1 1 |Frll,Frl6 1 21
3 I Frl4
1 I C3.US27
| US13, US29 I C2.US19
1 1 1 1
1 4 IUK1 1 5 I Sw2 1 6 |Frl,Fr3,Sw4 1 7 I Sw3
I C1,C5,US5,US7#US28,US35 1
I C4,US3,US9
1
I C7,C9,US8,US11,US21,US31 1
1 C6,US22,US26
1
1 8 |Fr9, Frl7
I US1
1
1 9 IFrl2,Fr4
I US12
1
1 50 |Fr7,N1,UK8,UK9
I US16
IY2, Cz2
1 1 ISwl,UK5
I US10, US32
1
1 2 |G3**
1 US4
1
1 3 |G15,It3
I CIO, US37
iJapl.Yl
1 4 |G7,G8,UK4,G19
I US18.US33***
|Y3
I 5 IG11.G16,G18, Frl5
1 US2,US17,US20,US34
1
1 6 |FR10,G1 1 7 |Fr8,G4,It2,G2
I US36*** 1
1 I Czl
1 8 |Fr6,Bl
I US23
I Jap2,Y4
1 9 |Fr2,It4
1
1
1 60 |G5,G13
1
1
1 1 |G9,G10,G12,G17,G20 ,G22| C8
1
1 2 |G6,UK6,G21,B2
1 US6
1
1 3 IFrl3, UK7 1 4 I Sw5 1 5 1 Fr5 1 6 |UK3, UK10 1 7 I It5
1 US38 I US30 1 1
1 1 1 1 I
Viola Maltoni
1 1 |
1 1 |
81 91 70 I 11 21 3 "!"
1 1 1 |
1
1 1 1 1 1 i
1I 1 Total 159
1 ! 45
1----------------18
11
1
1
* Cholangiosarcoma ** Aerosol can filler *** US33 and 36; and Fr 15 are still alive.
PJST80061400,2/WPX7-2
(Review date 1 January 1985)
Page 43
TABLE 8
WESTERN EUROPE PVC PRODUCERS - START-UP DATES vs ASL CASES (CLOTTING G03)
ISTAKT-OPl COUNTRY NATE | COMPANY NA1E I
LOCATION
I ASL CASE NUMBER 1
YEAR CF
YEAR 1
!
1931 IWest Germany Tbasf
1933 IWest Germany IWacker
1 iLudwLgshafen
iBurghausen
1 1
104,07,11,15
1 1st Exposure 1 157,54,55,53
1938 I Italy 1939 |France
iMbntecatini |Acna iRhone Poulenc ISt Fons
1 103,09,10,11,14, 146,48,56,41,43,
11
1
|l5,16,17
155,41,48
1940 1United Kingdcm|ICI
|Runcorn
1
1
1940 1United Kingdom|ICI
iHUlhouse
101,04
|44,54
1945 | Sweden
IKemanord
| SundsvaH(Stockvik) 101,02,03,04,05 151,45,47,46,64
I Switzerland llonza
ISins
1946 I France
iHhcne-Poulenc iRousillon
1 101
1 146
1947 1Italy
iMontedison
I Porto Margjiera
102
157
1948 lUhlted Kingdan|EP Chem
iBarry
103,05,06,07,08,09166,51,62,63,50,50
11 IWest Germany |Huls
1 |Marl
110 |09,10
p6161,61
1949 IBelgium
ISolvic
iJansppe
101,02
158,62
1950 iFrance
iPuk
iBrignoud
102,04,05,06,12 159,49,65,58,49
iFrance
iRhone-Poulenc |St Auban
107
150
IHolland
ISbell
iPemis
1
1
| Norway
I Norsk
iHeroya
101
150
1951 |Italy
| Montedison
(Btindisi
1
1-----------------------------
1952 IItaly 1953 IAustria
| Montedison iHalvic
|Temi lHallein
1 1
1 1
IFrance
ISolvic
iTavaux
108,13
157,63
IItaly
ISolvic
1 Ferrara
|03
153
| Spain
iRio Rodano
iHernani
1
I
|United Kingdom |BIP
lAycliffe
1
|
IWest Germany iHoechst
iGendorf
|18
155
1954 IWest Germany iDynamit 11
iTroisdorf 1
101,02,08,12,16, 156,57,54,61,55,61 > 1 117,19,20,21,22 154,61,62,61
1955 1 Spain
iMonsanto Tberia|Monzon
1
1
1956 ISpain 1
ICaiqsa IHispavic
ISabinanigo iTorrelavega
1 1
1 1
1958 |Wast Germany ISolvay
1960 IItaly
|S C Ravenna
iRheinberg |Ravenna
1 104
1 159
1960 IWest Germany iLonza
lUaldshut
106,13
162,60
1962 IPortugal 1965 IFrance
ICires
| Oporto
IRhone-Poulenc iMontlucon
1
1 1-----------------------------
IItaly
|Pozzi
iFerrandina
1
1
IWest Germany IWacker
I Cologne
1
1
1966 IWest Germany IHoechst
|Knapsack(Frankfurt)|05*
160
1967 IFrance
|AI0 Qdme
|Balan
v1
1
ISpain (Greece 1968 (Belgium
|Rio Rodano |Esso Pappas iBadiphil
| Miranda de Ebro iDiavata Salonika IAntwerp
1 1 1
1 1 1
1969 lUnited Kingdcm|Vinatex
IItaly
iRnnrianca
IStaveley
1
jCagliari Sardina 1
i 1--------------------------
1970 IItaly
ISIR
1Porto Torres Sar 1
i
lUnited Kngdcm|ICI
1971 1Italy
|S C Ravenna
ISpain
IHispavic
iRuncom IRavenna iMartorell
1
1 ! ""
i i i
ISweden
IKemanord
IStenungsund
1
i
lUnited KingdcmlBP Chan
iBaglan Bay
1972 iFinland
iPekema
ISvartback
IHolland
1DSM
lBeek Limburg
1976 IFrance
|Soc Art D'vinyl li^zingarbe
1977 ISpain
IMonsanto Iberia|Tarragona
Laboratory worker in Research Department
l
1 1 1 1
i i i I i
** Pinsec, Mira Venice, case not included. (It 05) due not knowing start up date of
PJST80061400.3/KPX7-2
GEM OO??'
(Review date 1 January 1985)
Page 44
TABLE 9
USA PVC PRODUCERS - START-UP PATES vs ASL CASES
I START-UP 1 COMPANY NAME
| LOCATION
I ASL CASE 1 YEAR" OF
YEAR 1
1
1 NUMBER
I 1st EXPOSURE
1939? |*ucc
| S Charleston
107,13,19,21,24, 144,42,43,46,39,
1 1 127,28,29,31,35 141,44,42,46,44
19 "40? |*BFG
| Louisville
101,02,03,04,05, 148,55,45,52,44,
! 1 106,09,16,17,22, 162,45,50,55,47,
11
126,33,34,37
147,54,55,53
1946? |*ucc
| Texas City
1
1947 I Goodyear
| Niagara Falls
108,10,11,20
146,51,46,55
1948 1 Firestone
| Pottstown
112
149
1 Uniroyal 1
| Painesville j (closed 1975)
1 1
1950 1 Monsanto
| Springfield
132
151
1952 I Dow
| Midland
I BFG
| Avon Lake
118
154
1953 1 Diamond
| Deer Park
1
1954 I General Tire
| Ashtabula
136
156
1956 1 Air Products
| Pensacola
1
| Atlantic Refining | Brooklyn
1
I Borden
| Leominster
1
1 Conoco
| Hebronville (Closed 1975)
1
I BFG
| Niagara
1
I Great American
| Fitchburg
123
158
| Plastics
| (Closed 1983)
1
- I Hooker
| Hicksville
i
1 Pantasote
| Passaic
1
1957 1 Atlantic Tubing | Cranston
1
1 Tenneco
| Flemington NJ
130
159
1958" | Keysor Century
I Saugus, Cal
1
1960 1 BFG
| Watson, Cal
1
1 Air Products
| Calvert City
138
1
1 | (closed March 1982 Re-opened October 1983)
1 Borden 1962 I Tenneco
| Illiopolis j Burlington NJ
1 i
1963 | Conoco | Stauffer
| Aberdeen, Miss | Long Beach, Cal
1'
1 1
1965 1 Conoco
| Assonet, Mass
1
1 Ethyl
| Baton Rouge
1
1966 I Diamond
| Delaware City
1
iGeneral Tire/Pantasl Mt Pleasant W Va 1 (Closed 1983) 1
1 BFG
| Henry, 111
1
| Stauffer
| Delaware City
1
1967 1 Allied
| Painesville, 0 **
1
1 I Hooker
| (sold to Robintech) | Burlington NJ
1 1
1968 1 Firestone
| Perryville
1
1969 I BFG
| Pedrickton NJ
1
I Goodyear
| Plaquemine
1
1 Olin
| Assonet, Mass (Closed 1975)
1
I (Formerly Conoco)|
1971 I Conoco
| Oklahoma City
1 1--------------------------------
PJST80061400.4/WPX7-2
GEMC 007974
TABLE 9 (Continued)
Page 45
USA PVC PRODUCERS - START-UP PATES vs ASL CASES
|START-UP | | YEAR 1 1972 | 1 1973 1
|
COMPANY NAME
Nat Starch Borden Robintech **
! 1974 I Atlantic Tubing 1 Shintech
1 1975 1 Certain-teed | Georgia Pacific I Tenneco
| 1979 I Firestone
I LOCATION
1 I Meredosia, 111 1 Springfield I Painesville, 0 ! (sold to Georgia I Pacific who 1 converted to 1 polystyrene) 1 Cranston RI I Freeport, Tex t Lake Charles 1 Plaquemine, La 1 Pasadena, Tex 1 Plaquemine
I 1
1
ASL CASE NUMBER
1 YEAR OF 1 1st EXPOSURE 1 1 1
1 1 1 1 1 1 1 1 1
1
* My databank has no information on UCC before 1946 or BFG before 1950
** Refer to same plant at Painesville. Allied plant never operated again for PVC after it was sold to Robintech.
NE Some of the plants in this list were closed down, some have changed ownership over the years
PJST80061400.5/UPX7-2
(Review dace 1 January 1985)
TABLE 10
Page 46
CANADIAN PVC PRODUCERS - START-UP DATES vs ASL CASES
|START-UP 1 YEAR | 1943 1(1941?)
I 1951
| 1957
1 1966
I 1979
COMPANY NAME
I LOCATION
I ASL CASE
1 1 NUMBER
Goodrich
1 I Shawinigan
I 101,02,03,04,05
1 106,07,08,09,10
11
Monsanto*
1 | La Salle
1 1
11
Goodrich
1 | Welland
1 1
11
Esso
1 | Sarnia
1 1
1I
11 Diamond Shamrock Alb I Fort Saskatchewan
!1
YE^R OF
|
1st EXPOSURE I
44,43,41,45,44, | 47,46,61,46,53 |
* Terminated 1975
PJST80061400.6/MPX7-2
.Review date 1 January 1985)
Page 47
TABLE 11
EASTERN BLOC PVC FACTORIES - START-UP DATES vs ASL CASES
I START-UP| COUNTRY NAME I COMPANY NAME
I YEAR 1
1
|Pre 19391 East Germany I State Company
| 1941 |Russia
|State Comps
I 1950 (Yugoslavia
Uugo Vinil
I 1951 (Czechoslovakia!State Comps
I 1955 |East Germany |State Comps
1 1956 |Rumania
|State Comps
1 1957 IPoland
(State Comps
I Rumania
I State Comps
1 I 1958 |Rumania
1 1 State Comps
1 1959 |Hungary
|State Comps
I 1961 I Rumania
I State Comps
I 1963 (Yugoslavia
(Ohis
I 1965 I Bulgaria
|State Comps
I 1967 IPoland
|State Comps
I 1969 I Russia
I State Comps
I 1970 (Rumania
I State Comps
I Russia
I State Comps
I 1972 (Yugoslavia
IVinilplastika
| 1975 |Czechoslovakia!State Comps
|Russia
I State Comps
| 1976 (Yugoslavia I 1977 |Rumania
1 Hip | State Comps
| LOCATION
1 | Schopau |Vladimir et al | Split |Novaky | Bitterfeldt llcechim (Oswelclm (Dwory) | Timaveni ITurda iRisnov |Berente Borsod I Borzesti | Skopje I Varna | Tarnow | Djerjinsk iRimnicu Vilcea |Volgograd I Zadar INeratovice iKalush Area | Pancevo IRimnicu Vilcea
I ASL CASE I NUMBER
1 1 101,02,03,04 101,02
1 1 1 1 1 1 1 1 1 1 1 1 1 I' ' 1 1 1 I 1
1 - YEAR OF 1 1st Exposure 1 1 153,50,54,48 157,50
1 1
I 1 1 1 1 1 1 1 1 1 1 1 1 1 1_
PJST80061400,7/WPX7-2
GO???"
genc
(Review dace 1 January 1985)
Page 48
TABLE 12
JAPANESE PVC PRODUCERS - START-UP DATES vs ASL CASES
1 START-UP 1
COMPANY NAME
YEAR
1950 I Chisso Corp
I Kanegafuchl Kag
I Tekkosha
1951 1 Mlcsul Toatsu
1952 1 Mitsubishi Mon
i Sumitomo Kag
1951 1 Denki Kagaku
-I Nippon Zeon
! Toa Gosei
1955 1 Ryo-Nichi
1956 1 Nippon Zeon
1 Nisshin Kagaku
1957 1 Kureha Kasei
1 Shinetsu Kag
1960 I Denki Kagaku-
I Kanegafuchl Kag
1964 I Chisso Corp
1966 1 Tokuyama Seksui 1967 1 San Arrow Kagak
1 Sumitomo Kag
1968 1 Ryo-Nichi
I Shinetsu Kag
1970 1 Chisso Corp
1 Denki Kagaku
1 Kanegafuchl Kag
I Kawasaki Yuki
I Mitsui Toatsu
1 Nissan Kagaku
1 Shinetsu Kag 1971 I Tekkosha
1973 1 Asahi Glass
1974 1 Toyo Soda
1975 1977
I Central Kagaku 1 Toyo Soda I Unknown
| LOCATION
1 | Minamata | Osaka | Sakata I Nagoya 1 Yokkaichi | Kikumoto | Shibukawa | Kambara | Tckushima I Uozu 1 Takoaka ! Takeo | Nishiki | Naoetsu 1 Ohmi I Takasago I Chiba | Tokuyama 1 Tokuyama | Chiba 1 Mizushima 1 Tokuyama | Mizushima 1 Goi (Chiba) | Kashima 1 Kawasaki 1 Sakai I Chiba 1 Kashima 1 Yokkaichi 1 Hayatsuki I Sakata | Yokkaishi 1 Kawasaki 1 Yokkaichi I Kashima
I ASL CASE 1 NUMBER
1 1 1 | 01, 02
i 1 1 1 1 1 1 I 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 ! 1 1 1 1 1
1 YEAR OF 1 1st EXPOSURE 1 1 1 1 53, 58 l 1 1 1 1 1 1 I ! 1
1 1
I 1
1 1 1 1
1 1 1 1 1 i 1
1
1 1 1 1
t r
PJST80061400.8/WPX7-2
.Review date 1 January 1985)
Page 49
TABLE 13
SOUTH AND CENTRAL AMERICAN PVC PRODUCERS
1 START-UP|
COMPANY NAME
1 YEAR |
1953 | Monsanto Mexica 1954 | Policyd
1955 1956 1960
1 Geon Do Brazil | Elchlor | Electrochlor
1961 1965
1 Viplastic | Indupa | PET Columbiana
1966
1967
1967
1 Carburo De Col 1 r SOC Paramanga , Plasticos Omega
1968 | Primex
1970 | Policasa
1 Petro Dow 1971 | Polimeros Hex
1975 | Rico Chemicals 1976 r Fetroplas
1977
' 1978
1979
| Indust Resistoc
r Huls Brasil
1 Polychera I Policyd
| PET Camacari
1 LOCATION
~r
1 I Lecheria (Mexico)
1 1
I Mexico City (Mexico)
1
1 Sao Paulo (Brazil)
1
| Sao Caetano (Brazil)
1
iCapitan Berraudez(Argentina)|
I Mendoz (Argentina)
I
1 Cinco Saltos (Argentina) 1
1 Cartagena (Colombia)
1
Medellin (Colombia) I
1 1
1 Pararaonga (Peru)
1
I Mexico
1
I Puebla (Mexico)
1
| Managua (Nicaragua)
1
I Conception (Chile)
1
1 St Martin Puebla (Mexico) 1
I Guyanilla (Puerto Rico) 1
I EL Tablazo (Venezuela)
1
| Tlazcala (Mexico)
1
| Cubato (Brazil)
1
I El Salvador
1
1 Coatzacoalcos (Mexico)
i
j Camacari Bahia (Brazil) 1
ASL CASE NUMBER
| YEAR OF
j 1st EXPOSURE
1 1 1 1 1 1 1 i------------
1 1 1 I
1 1 1 1 1 1 1
| I
1 1 1
PJST80061400,9/WPX7-2