Document 716d2ez77045p2Z4aB1Mqzd9e

August E* 1937 Dr* Carl M* H lllenbrand Plant Physician Harrison Radiator D ivision General Motors Corporation Lockport* Hew York Dear Doctor Hillenbrand* tI a a 3 e n d in ^ y oovu^hieerew ith reports on and The resu lt on^ B | i a within n o r m l^ fS x t^ ^ n fx o that on ^ ^ f l ^ f f o b a b l y not s i g n i f i c a n t l y h igh from cllrm ja3^ > oln t o f view but i s in d ic a t iv e o f some s lig h t lead exposure* or i t is at le a s t suggestive of such exposure* I am a ls o send in g you th com plete s e t of r e s u lt s on the blood samples and th e spot samples of u rin e which I obtained w hile at the plant* These are fo r your information aid for the sake of seeing the range o f valu es which i t is p o s s ib le to obtain in a group o f men who show no c lin ic a l evidences of In toxication * I have checked w ith a lead p en cil those re su lts which are s u ffic ie n tly h ig h to r a is e some q u estio n in one*s mind as to t h e ir s ig n ific a n c e * i f c l i n i c a l symptoms o f any kind were to d e v e^ i^ ^ a o w ey er , there i s only one* namely th at which is a sso cia ted with such sympTomB and p h y sic a l fin d in g s as might be in te r p r e te d as t o x ic symptoms due to lead* ' As I have in d ic a te d in a l e t t e r which I wrote Mr* Jen k ins a few days ago* I th in k a l l o f th e se symptoms and p h y sic a l s ig n s are b est explained otherwise* but the coincidence of such find in gs with a urinary value of 0*1? is suggestive* I would not take th e se too s e r io u s ly u n t i l we have obtained the r e s u lt s on S co tt* s la r g e samples sin ce * in our experience* r e la t iv e ly high flu c tu a tio n s can occur in spot samples* Moreoter there is always the p o s s ib ility of s lig h t contamination* In transm itting these resu lts to you* i t i s perhaps w e ll to in d ica te that in a group o f men whom we have been fo llo w in g fo r years* we se e o c c a sio n a l r e s u lts * even in la rg e samples* a3 h igh as two ten th s o f a m illigram per l i t e r in th e u rin e in men who are* so fa r a s tjo oan d etera in e* w ithout symptoms or 2 ** c lin ic a l evidences of in to x ic a tio n . However, such persons have a tendency from time to time to report at l e a s t vague s u b je c tiv e symptoms su g g e stiv e at ' d e f in it e e f f e c t s from lead # X am p e r so n a lly con vin or ce le d ss th c at on In sis t a e group n t ly In of e men xcess wohfo30e . r15e.smu litllsigarraemms opreer lit e r * bona f id e cases of lea d l u t o x lca tio n w ith vagao and, pertiaps, w ith nervous system involvement w ill be found* As X have In d ica ted to Mr. J en k in s, my rep o rt on a l l the d ata assem bled thus fa r w ill be sent along w ithin the next few days* Thanks fo r your b e s t w ishes fo r my h o lid a y which I hop to be a b le to s t a r t in ten days or two weeks. Cordially yours. RAK : I s R o e r F T 7 ^ 'eHoe7*TM73`. K B Gi) I 3 47