Document 6wajmVqgEBV1xZVLrv8dEzob9

# AR226-2872 Copies to: E. I. du Pont de Nemours and Company Haskell Laboratory for Toxicology and Industrial Medicine HASKELL LABORATORY REPORT NO. 521-78 Material Tested Haskell No. 12,401 Other Codes Sample Ready for Testing 7/6/78 Material Submitted .by Chemicals, Dyes and Pigments Department, ackson Laboratory * ACUTE ORAL TEST PrQC^ u^-: ^ material, as received or as a spsp$ialon in coin oil, as administered by intragastric intubation to young adult male ChR-CD fats in single doses, one anlial':jpf;vdose level'. Survivors were sacrificed 14 days later. faults: ' '----------- - ' .. : ------ ----------------------- -- Dose Suspension ___ (> Mortality* Clinical Siens Lethal^-Dper,;i 25*d00 & 11,000 I 7,500 m 5,000 3,400 *S a3 2,250 670 As.Received As Received 35 35 35 15 15 S - 14 d. s - i4 a. s - 14 d. s - 14 d. S - 14 d. S - 14 d. S - 14 d. S - 14 d. f^..il|S^iRB*4h6!F*^B'tit&-vite.*l'^a|M?/ar dosing at 250C ias after dosing at 670 mg/kg and above. >25,000 mg/kg. N aO. Mk v }has ver/y low t wo*x,i* 'c,i* *t7y wWhMe* n11 aamdMmiAini AisPtbecriecud voriaoluljyp, iAnll dsainugKAlce udoDsbecsd, to young adult male ChR- a c d rats, its Lethal nose is greater tH hl fal lni O2<5k ,0n 0n 0n MmMg// Lkgm *oCf Lbo. Jd.y. weight, the maximum feasible dosea l ___ _________ J _______ J ? __________ 1 . 1 . j\_______ o WCD 3 * S - ( ) d. Sacrificed ( ) days after dosing OSO 3ooP JEHrecg Report No. 521-78 k 0> I'M os1 * Dite Issued: S e n t a m W 22, 1978 ...... , ...... .. cCi i.'.w'kvivii-i'.Vr.Vv-i-.rUi.1;-.' ijiC o I .... 4 ..... .......- .-J.: (r r, >*'' j ') or,'.. w , , ____ , . Chief, Acute investigations Section