Document 6wG3e1MagxMK5jmRyB7aZdMJE
FILE NAME Talc TALC DATE 1972 Aug 3
DOC TALC150
DOCUMENT DESCRIPTION Report for FDA - Analysis of Products Containing Talc with Cover Letter
August 3 1972
Dr. Alfred Weissler Acting DirectorDivision of Colors and Cosmetics Technology
c
Office of Product Technology
Food and Drug Administration Department of Health Education Washington D. C. 20204
and
Welfare
Dear Dr. Weissler
,
final analytical results on the
Enclosed please foifnd10m2y examples of standard commercial
you
mineral compositions
containing talc
These include all the specimens
products from Washington
except for a few
principally the
sent me
will report on separately as
pharmaceutical specimens which I in New York and in Boston
well as a number that I purchased
show that 59 of the products have no
The analyses
of the asbestiform minerals by the
detectable amounts of any
by weight of 1-2 or less could
technique employed proportions but definite percentages of
escape detection 20 had small
of chrysotile 9 had small
tremolite 7 had small percentages
and 7 had sub-
percentages
of
both
tremolite
and
chrysotile
asbestiform minerals
stantial percentages of one or both of these
I shall retain and preserve the original specimens ray diffractograms until you advise me otherwise
and
the
With very best personal regards
Sincerely yours
1.3.2
1.3.2 .
1.3.2
SeymouZr. Lewin
Professor of Chemistry
CPC2-00000011
TABULATION OF RAY DIFFRACTION ANALYSES OF COMMERCIAL PRODUCTS CONTAINING TALC
A. Products having no detectable amounts of asbestiform minerals
limit of detectability 1 to % for each mineral
Product Talc
Mineral Composition
Chlorite
Phlogopite Quartz
Dolomite Other
HN
100
n.d.
n.d.
MIKO
100 n.d.
n.d.
MIKO
95
%
%
MIKO
80
%
Hm52MNNN
86 NAEMNA N80-22020
N80-22020
95
NAEMNA
Hm52MNNN Hm52MNNN
N80-22020
89
78
Hm52MNNN
N800-2222020
93
NAEMNA
Hm52MNNN
N800-2222020
90 NAEMNA
%
N800-2222020
100 n.d.
n.d.
N800-2222020
31
50
%
n.d.
n.d. n.d. A.d.
n.d.
"/ " "/ " "
n.d.
10
n.d.
n.d. n.d. n.d.
%
n.d. n.d. n.d.
%
n.d.
%
Znud
N800-2222020
60
30
18
90 %
" IJN21272N372
n.d.
ANAMAM
% %
20
35
60
21
679
25
22
"/ " 3" 5
23
"/ " 50
IJN21272N372 IJN21272N372 "/ " "/ "
ANAMAM %-
n.d.
ANAMAM
n.d.
3 %
%
2.5
95
%
"
n.d.
n.d.
26
955
1
IJN21272N372
n.d.
n.d.
27
88
n.d.
"/ "
n.d.
19
29
94
2%
"/ "
n.d.
%
Ci:
CPC2-00000012
Talo
Chlorite
47
50
80 " " "
55
40
78
!
78
2252ona
79
2252ona
38
50
87
94
""
66
"
81
89
89
%
96
n.d.
n.d.
nid
65 48 100 88 100 .95 100
30 40
n.d.
%
n.d.
%
n.d.
90
90 78 86
% % 15 %
96
n.d.
Mineral Composition
Phlogopite Quartz
3232
3232 3232 3232 3232
" S% ae
n.d.
" te bebe "" "
% %
n.d.
naa
10 15
n.d.
made % her her
n.d.
% _
n.d.
n.d.
%
n.d.
n.d.
%
n.d.
n.d.
2
%
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
" " " " "fi %
n.d.
%
n.d.
% %
4E
Dolomite
% % 3 89 % 7a.d. % %
n.d.
5 By %
n.d.
n.d. 4 %
n.d.
%
D.d. n.d.
n.d.
% ANJAN
n.d.
%
n.d.
Other
ZnO K
CPC2-00000013
B.
Products having small amounts of Tremolit~emore
but not more than % by weight
than
%
Product
Mineral Composition
Talc
Chlorite
Phlogopite Phlogopite
Quartz
= 60
61
30
61
35
40
n.d.
25
62
89
#HUHQHHHUNUNN
18
63
87
#HUHQH HUNUN
720AMA
n.d.
% ",, ",,
HNMI020 84
#HUHQH HUNUN
65
79
15
66
85
#HUHQH HUNUN
67
75
#HUHQHHHUNUNN
68
78
#HUHQHHHUNUNN
69
96
#HUHQHHHUNUNN
70
26
60
71
84
10
72
86 %
73
-79
10
74
92
n.d.
75
75
%
720AMA
c
n.d.
720AMA , 720AMA
n.d.
SAA
n.d.
n.d.
KHE FOHEN
FOHEN d
" " "
n.d. n.d. n.d. n.d. n.d.
INT INT
"" " 3
n.d. n.d.
77
915
n.d.
78
85
DR
79
86
"/ " " NIHI ",, " "
2% %
n.d.
Dolomite Tremolite
% 18 n.d.
n.d.
JEUUNEWS JEUUNEWS JEUUNEWS JEUUNEWS %
n.d.
JEUUNEWS
n.d. n.d.
% % 15
"/ " " " "/ "
2255ma
" "/ "
int2223
"/ " int2223 int2223 int2223 " " "
ammymum
ammymum "/
n.d.
FMN FMN
ammymum
"/ "
D.
3
CPC2-00000014
of Chrysttile -- more than 1 .
C. Products having t shman all amounts
but not more than 512 by weight
Product
Talc
80
48
81
80
82
76
83
81
84
87
85
83
86
82
Mineral Composition
;
Chlorite
Phlogopite
Quartz
4.0
n.d.
78
Fbers
12
Fbers
balde
Fbers
OT
SL
AL
8
IS
9
5%
62
45
n.d.
n.d. n.d.
%
Dolomite Chrysotile
n.d.
, , , Mot Mot Mot
4234527 4234527
4234527 4234527
"/ "fi 4234527 4234527
CPC2-00000015
oD.
Products having small amounts of both Tremolite and Chrysotile ==
more than % but not more than 2 of each by weight
Product
Mineral Composition
Talc
Chlorite
Phlogopite Quartz Dolomite Tremolite Chrysotile
87
28
50
88
61
n.d.
89
68
13
90
5215 %
n.d.
91
23
%
92
61
n.d.
93
55
be
94
43
%
95
879
n.d.
n.d. n.d.
% ",, "/
" " ", " " "/ "
n.d.
39dKIL
12
39dKIL
25
39dKIL
10
39dKIL
2505BROininite
60
2505BROininite
261665
20
261665
25
261665 ses
2505B25R05BOROiininniteinite
"
"/ " "/ " " "/ "fi "/ " " "/ " " "/ 77557NNIN " " "
"/ "fi
fnnnnUn
"/ " fnnnnUn fnnnnUn
"/ " fnnnnUn un un
CPC2-00000016
amounts of Chrysotile and
E. TRPermoodluicttse h-a~vimnogre sutbhsan tan5 ti1al2 by weight
Product
Talc
96
97
98 99
100 101 102
66 31
39
37 78 53 659
Mineral Composition
Chlorite Phlogopite
n.d.
%
n.d.
" % %
n.d.
"/ " "/ "fi "/ "fi " " ",, "fi " 3"
n.d.
Quartz
% % 40 40
n.d.
% %
Dolomite
" 35 ",, "
" " "fl "/ " 15
Tremolite Tremolite
% 12 % % % 25 10
Chrysotile
10 15 10 % %
n.d.
7
*
pen
9
we r
perulimntabes
sun
aey
wr
t
*
CPC2-00000017
NOTES TO THE TABULADTAETD A
1
All products tested were standard and commercial brands
purchased in drug stores or the drug departments of department
stores or markets in the cities of Washington D. C. New
York and Boston
-
i
2
All data are based upon continuous scan ray powder
precision diffraction patterns
tion is of the order
The
of magnitude
in terms of average devia-
of % absolute for each of
the mineral species reported The data are given in units of per-
'
centage composition by weight
detectability 3
The limits of
2 by of the order of magnitude of 1 to
mineral species cited..
by the method employed
weight for each of
are
the
asbestiform 4 A.
Where an asbestiform
mineral was indicated by the ray
pattern as being present to a definitely detectable extent its
presence was verified by the use of optical microscopy to dis-
close the presence of significant numbers of fiber particles
B.
pattern
Where the asbestiform mineral was indicated the ray as being present at the just barely detectable level *.
this was verified or rejected by employing the step tech-
nique over the regions of the questionable diffraction peaks
5
The following minerals were estimated by comparing the
sum of the integrated intensities at the diffraction angles
listed below with the corresponding summed integrated intensi-
ties at the same angles of standards composed of the pure mineral
Mineral
;
Theta Values Summed
Dolomite Quartz Chlorite Phlogopite
31.0 - 31.2 44.8-45.0 20.4 - 20.6 39.3-39.71
6.3-6.5 12.4-12.8 19.0-19.2 19.0-19.2 25.0-25.4 8.6-9.0 25.9-26.1 28.1-28.3 25.0-25.4
6
Only two of the asbestiform minerals were detected in
the products tested Each of these was estimatedby comparison with standards made up by mixing the pure mineral with pure talc
invarious proportions by weight For both unknowns and standards
the parameter measured was the ratio of the integrated intensity
of a diffraction peak relative to that of an internal standard
The internal standard employed was % by weight of Zn
The integrated intensities were summed at the following following diffraction
angles
;
ve
Asbestiform Mineral
. Theta Values Summed
Me
Chrysotile
Tremolite
:
3
12.0 - 12.4
10.4 - 10.5
24.3-24.8
27.4-27.6 27.4-27.6
30.6-30.91 33.2-33.4
a
ae
-
29.4-29.7 29.4-29.7 29.4-29.7
tS
.
.
r 4 \
,
Page 7
,
a
&
CPC2-00000018
7
Talc was determined by difference
80
The following abbreviations are employed
n.d. n.d. n.d.
n.d.
not detectable
= zinc oxide
= zinc undecylenate
K
Kaolin
=
Caco Caco Caco =
Caco
=
starch
calcite phase not identified identified
unimportantunimportant
because
deemed
9
In several instances the same brand of product was pur-
chased in different places at different times to
on the
mixture cConshideerabcle k constancy composition of the mineral
Considerable
of
variations
were found
See product numbers 14 and
22 22
*
wereother precision and 23 ,
other instances constancywithin the
of
e.g. the analytical methodwas observed
in the case of prod-
uct No. 7
Page 8
CPC2-00000019
-
Product Number
Haim Haim
Haim
Ihonon Ihonon Ihonon Ihonon Ihonon
Ihonon
10
11
12 13
14 15 16 17
18 19 20 21
22
23 24
25 26 NNGONG NNGONG 29 39
31 32 33
35 36 37
39
40
~
KEY TOPRODUCT NAMES
Product Name
Further Identification
AMMENS POWDER MEDICATED AMOLIN DEODORANT POWDER AQUAMARINE COOLING SPRAY BATH
POWDER
BAGATELLE AMBER DUSTING POWDER
BOURJOIS BATH POWDER
CALDESENE MEDICATED POWDER CASHMERE BOUQUET BODY POWDER
CHANEL NO 5 BATH POWDER COUNTESS ROCHEAU CAKE DUSTING
. POWDER CREPE DE CHINE DUSTING POWDER
MILLOT
CREPE DE MILLOT
CUTICURA
_
CHINE POUDRE MIST
, .
TALCUM POWDER
DESENEX DESITIN BABY POWDER
DESITIN BABY POWDER
DIAPARENE BABY POWDER . DOROTHY GRAY SECRET OF THE SEA
:
i
DUSTING POWDER
EMERAUDE TALCUM POWDER
ENGLISH LEATHER FABERGE BIC DUSTING POWDER
FRIENDSHIP GARDEN DUSTING POWDER
,
FRIENDSHIP GARDEN DUSTING POWDER
'
PRIENDSHIP GARDEN DUSTING POWDER HEAVEN SENT AEROSOL BATH POWDER
MIST
HEAVEN SENT BATH POWDER
HELEN PRESSL LITTLE LADY
: IMPORTA SPAIN MENS TALC
POWDER : ISIS FLORAL TALC POU WDM ER
, JOHNSON'S BABY POWDER JOHNSON AND JOHNSON MEDICATED
i
POWDER
i KOSCOT BEAUTY DUST OF MINK
/ LANVIN ARPEGE DUSTING POWDER i LANVIN ARPEGE POWDERED MIST
} LANVIN ARPEGE TALC
+ LEWIS BABY POWDER
, LOVES FRESH LEMON GLOSSY POWDER ; MACY'S SCENTED BORATED TALCUM
i MACY'S TALCUM APPLE
, MARCELLE DUSTING POWDER HYPO-
:;
ALLERGENIC
MARY CHESS PERFUMED DUSTING
POWDER
Bristol No. IF25
Norwich
Revlon 143 Corand DCH
Pennwalt 5274
Palmolive
Jergens House of Fragrance
'
L1132
House of Fragrance
Purez 07170 Pharmacraft Pfizer 11392 3/29/72 Pfizer 115A 5/10/72
Breon E1080
Coty 355-4010|
Mem
2891 Shulton 3/27/72 Shulton 5/9/72 Shulton 7/13/72
Rubinstein
Rubinstein
028Q 3612
1288
Manley & James
2K4 .
CPC2-00000020
emnts,
Product Name
ne
MENNEN BABY MAGIC POWDER
HENNEN QUINSANA FOOT POWDER
MERCK
MEXSANA6460 ; NO
PRODUCT NO 6460 LOT
6460
2387 MEDICATED POWDER
OLD SPICE BODY TALCUM
PERSIAN LILAC DELUXE DUSTING
POWDER
PERSIAN LILAC SPRAY BATH POWDER
POND'S PERFUMED TALC BODY
B112 H202
8039301
Plough
Shulton
7
<
April Showers LFN April Showers B200B
DEODORANT DREAM FLOWER
_
PRINCE MATCHABELLI BELOVED SPRAY
115B
: ,
: POWDER
QUEST DEODORANT POWDER
REPLIQUE SPRAY BATH POWDER
RIVIANA FOODS - ITALIAN STEARIN
SEPTEMBER MORN BY POND'S SEVEN WINDS AFTER BATH TALC
US P TALC
Parfums Raphael 004
TALC- For Rice
19B
DuBarry
021085
VASELINE INTENSIVE CARE
IVES SAINT LAURENT RIVE ZBT ZBT BABY POWDER
ZEASORB SUPER ABSORBENT
BABY POWDER GAUCHE SPRAY TALC
MEDICATED POWDER
I 209
.
1021
Stiefel
1 , L
AMBUSH DUSTING POWDER
APRIL SHOWERS
9884
AVON UNFORGETTABLE PERFUMED TALC
BELOVED PERFUMED DUSTING
COTI FACE POWDER RACHEL
DESERT FLOWER SPRAY BATH
POWDER POWDER
PRINCE MATCHABELLI
Shulton F 1 BKI
EMERAUDE DUSTING POWDER
Coty
EMERAUDE SPRAY DUSTING POWDER
FABERGE FLAMBEAU DEODORANT SPRAY POWDER
Coty
1 AEY 37 WBF
DUSTING EATH JEAN NATE SPRAY
JERIS TALC FLESH
JOLIE MADAME DUSTING
POWDER POWDER
BALMAIN
LADY ESTHER FACE POWDERPOWDER RACHELRACHELE
MAX FACTORFACTOR FACE POWDER RACHELLE MEDICATED COMFORT POWDER
1 *
;
Davis
247
; 7
OH de LONDON
LONDON TO KNOW ME
GLOW TOUCH AND
TALC
Yardley
TO LOVE ME - TINKERBELL
Tom
FACE POWDER CREAMY PEACH
498 Fields
Revlon
Ltd.
TOUJOURS ZOI BATH POWDER
Corday
HARDLEY APRIL VIOLETS
;
4908
CHANTILLY DUSTING POWDER
CASHMERE BOUQUET
JEAN NATE TALC
MENNEN
SHAVE SHOWER TO BABY PURE
DREAM > ROND'S
TALC
;
SHOWER BODY BODY POWDER SHOWERPOWDEPR OWDER DART DRUG
PPERFUMED ERFUMED
FLOWER +
,
*
;
. Houbigant Houbigant
_
E
a
'
Johnson &
4
TALC
.
-
381
Johnson 5507BG
K. 110
013D 013D
.
:
.
;
Page 10
yo
CPC2-00000021
Product Number 87
Product Name
Further Identification
ALMAY ALLERGENIC FACE POWDER CONSTANCE CARROLL BOUQUET TALC
DJER TALCUM FLAMINGO DUSTING POWDER TUSSY
_
LANDER LILACS AND ROSES TALC
.
MAVIS TALCON
MAVIS BODY POWDER
TANGEE
ZBT BABY POWDER
Kerkoff
L1047
Vivaudou Vivaudou
Luft Tangee B0048
BLANCHARD'S DUSTING POWDER
BORN WILD DUSTING POWDER LANDER GARDENIA AND SWEET PEA TALC LANDER LILACS AND ROSES DEODORANT BODY
MISS DIOR DUSTING POWDER
TAI WINDS SPRAY TALC
Del Labs
TALC
Avon DCC 1272 2-14-72 2-14-72
TOSCA DUSTING POWDER
Pane Pane 11
CPC2-00000022