Document 6w81Vp2pYwXBYdwQ27X7aYwO3

Benzene Health Research Consortium Technical Committee Draft Minutes EA Conference Call - 10 Dec 2004 Participants Michael Bird (ExxonMobil) Steve Bowes (ExxonMobil) Don Burnett (BP) Stuart Cagen (Shell Chemical) Patsy Clegg (OC; Shell Chemical) Brian Doll (OC; ExxonMobil) Jennifer Galvin (ConocoPhillips) Steve Lerman (ExxonMobil) Shan Tsai (Shell Chemical) Tom Armstrong (EMBSI) Rob Schnatter (EMBSI) Yimei Zhou (EMBSI) Mark Fitzsimmons (Steptoe & Johnson) Bruce Jarnot (API) Lorraine Twerdok (API) Administrative Items Conference Call conducted in accordance with API antitrust guidelines Agenda -- discuss and review Exposure Assessment (EA) component of the Shanghai Health Studies (SHS) o Develop update for Oversight Committee meeting on 12/16/04 o Discussion based on "Review of SHS Exposure Assessment' presentation, prepared by Tom Armstrong, Rob Schnatter & Yimei Zhou Review of SHS Exposure Assessment Presentation & discussion led by EMBSI participants EMBSI subcontracted through Univ. Colorado to provide Exposure Assessment (EA) support to CC, DP and ME studies EA metrics summarized o Same population evaluated for CC & DP studies o Benzene poisoning (BP) cases evaluated separately Draft, pending revision & approval Page 1of2 SH ELL-MCCLU RG-057058 Benzene Health Research Consortium Technical Committee Draft Minutes EA Conference Call - 10 Dec 2004 o Incidence of observed benzene exposure (5%) is lower than predicted o "Others" refers to "other" non-benzene chemical exposures o ME studies recruit from active worker populations o ME study includes area & personal monitoring, plus biological monitoring (exhaled breath, urine) EMBSI timeline reviewed o Delayed start reflected by low initial rate of expenditure (9/11, SARS) o SRP recommendations changed initial scope o Jan '03: IPHS role change, limited to regulatory oversight IPHS database access limited Factory access limited Exposure sample analyses conducted by JCML Pis may reconsider method to recruit ME 2b workers o Chinese have a different cultural relationship with clinicians o Consent form might be revised to better reflect that relationship Draft, pending revision & approval Page 2 of2 SH ELL-MCCLU RG-057059