Document 6bnd1LXJQg4bEymD63dY50xK4
URL 15127
Liver Angioaarcoina Caeca
Cire illation
Ur A Hoes Admaa, Air Products Hr P N Andoraon, Wilton Ur W C Barnes Jr, Monsanto USA Ur John Barr, Air Products Ur Peter Banter, EhAS Dr Brian Bennstt, Hillhouee (20 copies - 1CIA, ALCI, Duperlal) Ur pie ire Bertarzi, Milan University Dr Bescha, Dynasit Nobel, Troiodorf Dr W best, Everberg Ur C Bishop, BUS Ur E Bouges, AtCl Ltd, Plastics Div'n, PO Box 1122,
Johannesburg 2000, South Africa Dr David Bryson, AQ Division Mr David Burgess, 1CI Americas Ur David Byren, Kemanord Dr J I Carter, BP Mr C Celia, Montepollaeri Mr M Chance, VCN Technical Manager, Mond Mr P Q Cleue, APK Hr Harold Clayton, Norsk Hydro Dr Contassot, Chios Chimie, St Fons Dr E W Dscey - NXOSH, Cincinstti Hr J G Device, Everberg Sir Hichard Doll, Worden, Oreen College, Oxford Hr Q Dupont, ACME Mr II Eaninger, VKE Dr W Ernst, Berufsgenossenschaft der cheaischen
Industrie, Nurnberg Dr Henry Falk, CDC Atlanta Dr D M Ferguson, IC1 Americas Dr H P Friedel, Beru/sganossenecheft der chemiachen
Industrie, Heidelberg Prof L Golberg, Duke University Medical Center, Box 291**
Durhaa, North Caroline 27710, USA Dr B E Gosztonyi Jr, Teaneco Chemical*, Saddle Brook (HJ) Dr Welter D Harris, Uniroyal Inc Dr Donald W Hillaan, Diamond Shamrock Dr Bobert K lllnderer, Bf Goodrich (Cleveland) Mr J Hodgson, EMAS Dr W A Hogg - Imperial Oil Ltd, Canada Dr J K Howard, Wellington Clinical School of Medicine,
Univeraity of Otago, Wellington Hospital, Wellington, New Zealand Dr N f Huaphry, ICI Australia Operations Pty Ltd, PO Box `Oil
Melbourne, Victoria 3001, Australia Hr J Jauvert, Chloe Chisie, Paris Mr II 8 Jervis, Hillbank Dr M N Johnson, BF Goodrich Dr Bruce Karrh - Dupont Dr B A Krueger, BF Goodrich Dr J P Laloine, Solvay
Hr J Lawrence, SPI Ur F 1 Lee, Victoria Hospital, Blackpool Prof V K Laibach - University of Bonn Dr D A Levison - St BortholotMW'u Hospital, London Sr P Lewie, CIA Mr Lolivier, Solvay Prof 8 N M MacSween - Western Infirsary, Glasgow Dr J M Maillard, Mediainiscbe Abteilung, Suva,
Poetfacb 6002, Luzern, Switzerland Prof C Maltoni, Bologna Dr Kenzo Mattiussl, Montedison Mr Mokkn, Naate Oy Dr B Honteeano, larc, Lyons Dr A A Kotti, Duperiel SAlC, Buenos Aires Dr A Munn, Monsanto, Brussels Mr M Munoz Mouton - Bio Rodano Mr. S Nakaaura, Japanese PVC Association Dr John J O'Sullivan Mond Dr B Owen - TUC Dr 0 M Paddle Dr S Paglialunga - Montedison Dr Hans Popper, Mount Sinai Medical Centre Dr J Possberg, Wacker Dr Jiutea Purdlias - Canadian Centra for OHS Mr P Bangnee, Norsk Hydro Dr B Saracci, larc, Lyons Dr David Seronne, Diamond Shamrock Dr Paul M Smith, Llandough Hospital Dr B Splrtae - MCI/HlII Betbesde Dr Carol Stack, CMA Washington Dr J Stafford Hr Stahnecker, BASF Prof C U Taaburro - University of tauisville Dr Gary Ter Hear, Ethyl Corporation Dr B Terwiesch, CWH Dr Gillas Theriault - McGill University Prof Or Thiess, BASF Or E Thiis - Evenaen, Norsk Hydro Dr W Tordolr, Shell Dr T H Torkeleoo, Dow Mr J B Wallace, Esso Cheaical, Surnia, Caneds Mr S 0 Wajdling, Keaanord Mr k N Wheeler, UCC Dr J Whiston, Uillhouse Mr K H White, Duperiel SAIC, Buenos Aires Dr I W Williams, Norsk Hydro Jr 0 H J Willluma, BP Barry Dr K S Williamson Dr Peter Wright, P & P Wilton Mr John Tork, Everberg
RECEIVED
FEB 15 1984
MEDICAL DEPARTMENT
t
17 Jan 8A
82 is nun
PREFACE ACKNOWLEDGEMENTS, SIGNIFICANT CHANGES AND COMMENTS
1) Since John Stafford's retirement from ICI, I am pleased to say that he has been elected an
Honorary Fellow of the Faculty of Occupational Medicine at the Royal College of Physicians,
London.
(
2) I would like to thank Dr Paglialunga for all his patience and hard work in helping me to acquire the necessary facts which enabled me to place the recent Pansac ASL in the Register.
2) I would like to thank Dr Laundrie, General Tire and Rubber Company, Akron, Ohio, and Dr Dacey, Robert A Taft Laboratories, Cincinnati, for informing me of recent ASL cases.
j
A) I am grateful to Dr Contassot for sending me information about three new ASL cases which have occurred at the St Fons* Factory in Lyons, and also for the full account which he gave.
5) I should be very grateful if I could be kept up to date with the five ASL cases which I have placed in the Register, who are all still alive at this present time.
6) I would like to express my appreciation for all the help I have been given in carrying on the work of John Stafford by everybody who has sent me their helpful comments and communications.
7) On taking over the Register, I discussed with Dr John Stafford his present format. We both felt this would be the appropriate time to consider any worthwhile comments about its presentation, and also suggestions for any way it could be improved, in order to benefit future analysis.
B BENNETT 17 Jan 84
63 is nan
Table Sequence
Belgium
Canada
Czechoslovakia
France
Germany
Italy
Japan
Norway
Sweden
UK
USA
Yugoslavia
Incidence of Cases pa (Table 1)
Distribution of Cases
by Country
(Table 2)
Pattern of Cases by
Factory
(Table 3)
Latency Periods (Table 4A)
Distribution of Latency Periods (Table 4B-4H)
Annual Geographical Incidence (Table 5)
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER ANGIOSARCOMA CASES (REVIEW DATE - 1 JANUARY 1984)
1 2-3 4 5-8 9-13 14 15 16 17 18-20 21-26 27 28
29
30
31 32-8
39
ASL Case Numbers by year of Death (Table 6)
ASL Case Numbers by year of first exposure (Table 7)
Western Europe PVC Producers - Start-up Dates vs ASL Cases (Table 8)
USA PVC Producers - Start-up Dates vs ASL Cases (Table 9)
Canadian PVC Producers - Start-up Dates vs ASL Cases (Table 10)
East European PVC Producers - Start-up Dates vs ASL Cases (Table 11)
Japanese PVC Producers - Start-up Dates vs ASL Cases (Table 12)
South & Central American PVC Producers - Start-Up Dates (Table 13)
oeist wi
40 41 42 43-44 45 46 47 48
IMPERIAL CIIEH1CAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER Angloearcuua Cases - (Review Date; 1 January (984)
Purs 1
11
t d* I COUNTRY AND | REFERENCE | NO
2
NAME OK INITIALS
1
DATE OF BIRTH
4 COMPANY
1 BELGIUM 1 01
12.01.n Solvsy
5 FACTORY
Jenepps
6 FIRST VC EXPOSURE
00.07.58
7 DATE OP DIAGNOSIS
00.05.76
a ACE AT DIAGNOSIS
63
9
YEARS OF EXPOSURE TO
MAGNOSIS
18
10 11
YEARS OP DATE OF
EXPOSURE
DEATH
17 29.06.76
12 IIISTOLOCICAL CONFIRMATION
Yes
1
13 (
14 |
15
1 (
ESTIMATED I
OTHER
OTHER
EXPOSURE I OCCUPATION 1
CAREER
COMMENTS
LEVEL . |
HIGHLIGHTS
1
t
1I
High (AuCocleaner | Driller In
I lllepaclc casta
(14 yra 1958-1968 |
| foundry (2 yr>
(In Oct 1974 (were norea).
exposed to|Poiyuorker | Pa rue r
200 ppn (3 yra
| (11 yra)
(Retired |Feb 1975
for 8 hra |
| Work In glass (Hospitalised
per day |
lnd. k cheel- (May 1976
and
|
certainly I
| cel Industry I I Couplets
under 500 ppe
1 |
|Clinical and (career detalla
In,6 to 9m3
| l
|are given In a (paper by
autoclaveel
(llublet et el
(968-1972 l
|ln Arch. Belg.
exposed co| 50-200 pp*| 8 bra per |
(Mud. Soc., (Ilyg. Med. 1'1'rav. Had.
day In 25n3
| (
|L*=g. 11977 pages
autoclaveel 1972-1974 | exposed to| 50-200 ppe| In auto- | clave rooa| 1974-100 |
(601-622
I l I i \ I
PP
1
1975- 50 |
1 I
PP"
I
RETIRED |
1 Feb 19751
I l I
1I
1I
1I
1I
1I
(I
1I
s(
1I
l..................................... J_ _
lets nan
IMPERIAL CHEM CAL INDUSTRIES PLC PETROCHEMICALS NO PLASTICS DIVISION
LIVER Angtoaarcoua Caned - Review Date: 1 Jan I9B4)
* All dstea use UK lyitea
Canada
DAY - MONTH - YEAH ** Data published In Journal of
Sheet 1
Occ Med 1978 paged 338-340
*** Many of dataa altered to fit KlOSli 31/3/77 Hat
Page 2
10
12 13 14
15
lb
COUNTRY AND REFERENCE NO
NAME OR INITIALS
DATE OF BIRTH
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
ACE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
OTHER COMMENTS
CANADA 11 l 1 01 il
1* 1 02
; !|
|l 03
h
i
i 04 i i
ii
05 1
i i i Ob i i i \ i 07 i i
i 08
i i i i 09 i
ii
1 1 1 1 1 1 1 1
1 1 1 1 1 1 I 1 1 1 I 1 1 1 1 | I l 1 1
\ 1 1 1 1
| 1 l 1 | 1 1 1 1 |
SHAM1HICAN
11 |I5.12.13 |
11
1
1
1
1 11
1
1 1944 i 1955 1 41 I n
1 11 102.09.55 1
Yea
11
11 11 106.03.14 |
11
1
1
1
1 11
II
1
1
1
1 11
11
1
1
i
1 11
1
1 1943 1 1957 1 43 1 14
1 14 121.12.57 |
Yes
11
11
1
1
1
1 11
1(
11
1
1
1
1 11
11
1i (26.08.19 I
11
l
1
1
1 11
t1
1
1
1
1 11
1
1 1941 I 1962 1 42 I 21
1 20 123.03.62 1
Yea
11
I1
1
1
1
1 11
11
11
1
1
1
1 11
1\
11 (05.04.19 |
11
1 _1
1
1 I1
11
1
1
1
1 11
1
1 1945 1 1967 1 48 1 22
1 22 121.01.68 |
Yes
11
11
1
l
1
1 11
11
11
1
1
l
1 11
____ __1 1
11
1
1
1
11
< ______ L_
1
1
1 1I 1 11
11
11
1
1
1
1 I1
107.05.11 1
1
i 1944 1 1968 1 57 1 24
1 05 105.07.68 |
Yea
i1
li
1
1
1
1 1I
11
1I 115.12.19 |
1t
1
1
i
1 11
1i
1
1
1
> i1
11
1
1
I
1 11
l
1 1947 1 1971 1 51 1 24
1 23 110.04.71 |
Yea
11
1I
1
l
1
1 11
11
11 1t 109.11.19 |
_1 I
1
1
1
1l
i
1
I
1 11 1 11
11
1
1
1
1 11
1
l 194b i 1972 l 53 I 26
1 25 124.12.72 |
Yes
11
11
i
1
1
1 11
11
11 1I 113.05.20 1
1l
i
1
1
1 11
1l
1
1
1
1 11
1l
i
1
i
1 11
1
I 1961 i 1973 1 53 1 12
1 05 (12.06.73 |
Yea
1
1 1 119.07.21
1
1 1 I
1I 1 ______ L.
-i1--
1 !
I 1
1I
i
1
1
1 I 1946 I 1974 1 S3 1 28
1 11
1 11 1 11 1 26 104.09.74 |
Yes
11
1i
i
1
i
1 11
11 11
1i 1I
-1 1
l _!
l 1
1 11 1 1________ ___ L
1 |
1 1 1 |
1 1 1 1 |
1 1
1 1 1
1 1 1 1 1 1
1 1 1 1 |
1 1 1 1 |
1 1 1 1 |
1
1 1 |
1 1
L
1 |Reactor
(cleaner
1 |Operator
1 (Smoker
|polymerlaation|
1 1 IMalatenonce (millwright. Iplpeflccer
1 1 (Operator, | foreman
( 1
1 I Reactor | cleaner
1 1 |Operator
1 1 1 1 1 1 1 1 1 (Operator, |foreman,
1 1 |Worked (overtime |Smoker
1 1 |Worked (overtime | Non-uiaoker
1
1 (Worked lovertime
1 (water cooling I Smoker
1
(unit
1
11
1
1 | Reactor
(cleaner
11 (Water cooling (Worked
(unit
(overtime
JJ 11
(Smoker 1
1 | Reactor
1( (Maintenance, (Worked
*
Icleaner
1 1
(millwright
1 1
(overt isie I Smoker 1
1 |Reactor Icleaner
1
1 IHachlne ehop loperator and
Ipoly unit
1 (Worked
(overt tme |Smoker
1 1 |Reactor Icleaner
1 1 |Maintenance
leadline ehop
1
( I In pi ant (25 yral Smoker
11
11 (Furnace op. 1 (pipefitter 1 (maintenance 1
1 1 (Worked (overtime |Smoker
J1
1
!. Paper by Dr F DELORME In Annalea d An at oiale pathologlque Parl9, 1978 Vol 23 No 2 pplOS- 114 clalmu this caae had both a hepatoma and ASL aleultaoeoualy,
ZBSUbH
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER Angloaarcuna Caaea - (Review Date: 1 Jan 198A)
DAY - HDNTH - YEAR
Sheet 2
All dates uae UK ayatea
Canada
** Data published In journal of
Occ Med 1978 pages 338-340
*** Many of dates altered Co fit NIOSH 31/3/77 list
Page 3
1k 1 l I COUNTRY AND | REFERENCE | NO
1 k 1 CANADA 1| | 10
1 1
I l
2 131
1! kl NAME OK | DATE OF 1 INITIALS t BIRTH 1 1i
11 11 1t 1I 116.05.IS i
1I
1l
4 COMPANY
1 51 6
11 \k 1 1 first vc | FACTORY | EXPOSURE
11 LL 11 I1 ik t 1 1953 i1 11
DATE OF DIAGNOSIS
1976
8 ACE AT 01ACN0SIS
61
9 10 I u
YEARS OF
>.... 1 YEARS OF | DATE OF
EXPOSURE TO EXPOSURE I DEATH
DIACNOSIS
I
JL 1
1
1
k 23 14 100.04.77
1
12 HiSTOLOCICAL CONFIRMATION
Yes
13 1 14 1
15
l1
J1
ESTIMATED k
I
EXPOSURE ) OCCUPATION I
OTHER CAREER
LEVEL t
I 1I1CHLICHTS
11 k1
Il
k |Reactor
1 (Furnace op.
{cleeoer
(Maintenance,
I (packaging
1 16 k 1 1 OTHER 1 COMMENTS
1 1 J k
1 | Ex -smoker
1 1
EC LSI ibn
at COUNTRY AND
REFERENCE
NO
NAHE OR INITIALS
DATE Of ttlftTH
C2ECIWSI.0-
01 28.06.28
06.07.27
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AMD PLASTICS DIVISION
LIVER Angiosarcoma Cases - (Review Date: I Jan 1984)
page a
10
12 1) 14
IS
16
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
ACE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF HISTOLOGICAL
DEATH
CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
OTHER COMMENTS
Novaky
01.07.S2 24.12.73
45
16
24.12.73
Autoclave Cl eaner
1ARC letter of 1-4-82 diving detail# fro* Prof A David of Centre Ind Hygiene and Occ diseases.
Novaky
01.11.SO 27.11.64
37
14
26.11.64
Autoclave Cleaner
IARC letter of 1-4-82 gave euaewliat altered dates for Llile ceae. 1 have accepted the changes since the datea coaie fro* Prof A David uf the Centre of luduetrlal Hygiene and Occupational Dteuaeea. Hy dates cum originally fron NIOSH.
whs nun
IHPEKIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER Aiigloaarcaiaa Cases - (Review Date: 1 Jan 1984)
France Sheet!
Page 5
COUNTRY AND REFERENCE NO
NAME OK INITIALS
DATE OF BIRTH
FRANCE 01
IS,04.24
02 03.06.11
03 NAV
06.01.20
04 27.01.27
05 29.01.38
COMPANY PCLIE
FACTORY Kouaa-
lllon
Brlgnoud
St Fona
Brlgnoud
Brlgnoud
FIRST VC
exposure
00.01.46 06.07.S9
00.00.46
19.10.49
18.01.65
DATE OF DIAGNOSIS 18.02.b7 1S.01.7S
15.01.75
16.01.76
13.05.76
ACE AT DIAGNOSIS
63 55 49 38
YEARS OF EXPOSURE TO
DIAGNOSIS
10 1 11 _L
12
YEARS OF | DATE OF EXPOSURE | DEATH
HISTOLOGICAL CONFIRMATION
19 119.02.67
Yea
124.01.75
Ye# (NIQSU no
coaaent)
29
29 129.06.75
Yea
26
26 104.01.76
Yea
113.05.76
Yea
sets nan
11
1|
13 1 14 1 is 1 16 l
1I
I1
ESTIMATED 1
1
EXPOSURE | OCCUPATION I
OTHER CAREER
i1
1 I OTHER
1 |
) COMMENTS (
LEVEL 1
| HIGHLIGHTS 1
1
11 1
11 1 I
1I
1
1
11 l 1
High (Autoclave 1
|Kef. Ravler ell
(worker and 1
(cleaner
1
(el Arch. Hal. | (Prof. 1 30 n4 l
1(9 yra 1
1 1
|3 Mov 75 |p 171-177
) |
11 1 1
High
1 |2 yra un
1 (Italian
1 (Ref.
1 1
(monomer
(origin
|G Bonneton et |
110 yra un Ipolymer((gallon
1
( 1 l 1
|al "Nouvelle |presae (medicate" IS Nov 1977
| J ( |
11
IP 735
1
11 1 I
High
1 I Polyworker 110 yra aa
11
(VCM production)Kef. Kety et |
(16 yre
lal Arch. Hal. |
|autoclave (Italian POU IProf. 1 37 n* |
leleaner
(Shepherd,
|6 June 7T
|
1 Compounding (Sawyer, Mason |p 551-55S
|
13 yra
1
1
1
1 1
11
11 1I
High |Monomer
1
1I
(production I 1 l
|worker
1
1
1
18 yra
1
1
I
|PVC
l
l
1
(filtration 1 1 I
116 yra
1
1(
High
1
1 (Polyworker
l 11 11 1
|1)Thoracotomy |Ref. P Coudcrel
111 yra
|9ih Feb 1976 (et al "Seaalne)
I
| coatal
Idea hospltauK |
l (angiosarcoma (10 Septembre |
1
(2)Sclntigraphy|1976
|
I
| found ASL
(Previously liodl
1
)3)Haumorrhaga (buna
|
i
(from ASL
(angAoaarcoaia** |
1
|4)Rlght
|AUo
|
1 (Hepatectomy (Pllicliowski et|
1( 11 l1 lJ
|al "La Nuuveile
(Presae Hedlcale
17th July 1979 I
IPaice 2485
1
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER Augiosarcoaa Cased - (Review Datei 1 Jan 1984)
France Sheet 2
Page 6
4
COUNTRY AND
REFERENCE
NO
NAME OR INITIALS
DATE OP BIRTH
FRANCE 06
14.04.34 PCUX
07 C1R
26.04.27
08 01.04.34 Solvay
09 08.10.14
FACTORY
PIRST VC EXPOSURE
Br Igooud 01.03.58
St Aubsn 01.07.50 23.05.57
St Fane
10.01.48
DATE OF DIACN0S1S
12.08.76
After death NIOSH Bays 00.07.76 03.12.75
26.04.76
ACE AT DIACNOSIS
42
49 42 63
10
14 IS
16
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OP EXPOSURE
DATE OP DEATH
HiSTOLOCICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
1
| t
|
OTHER COMMENTS
18 13 2b 22 19 19 28 28
9^nan
11.09.76 (NIOSH says 12.09.76)
02.07.76
Yea (HIOSH no
coaiaent)
30.01.77
Yea
25.12.77
Yea
HlRh
Moderate
Very High 1948-1966 Leaser Exposure 1966-1976
(1958-1960) 2 yrs filtration 10-11 yrs polyworker and works lab!
Plant foreBan In polymer isation
1972-6 adaln aectlon In St Auban
6 yra packer 6 autoclave clnr 14 yra autoclave worker
Polyaer-
10 yrB In
leatloo
aulphurlc
operator,
acid factory,
autocleauer, storekeeper 6
autoclave
general
aalntenence service*
1 I I
I Tills Mao had
|A0L prior to (AS. Ann. da |Mal. Prof.
(July *77 |p 64S 6 6.
IAOI, waa found lln 1971 five
lyrs before
| ASL
I l
|Died of
Isepticaeala
|Snail liver |lesion found (after autopsy
I I
(Had been (tunnel workur
(previously
I I I I i
(Operated 4.76 (fur reaoval of
(tuaour froa (liver and Idled after (second
leurglcal
(operation for Iblllo
(bronchial (fistula I Paper by
IDi Rety et al |In Archives de IHelades (Professlonals
(Vol 40 No 6 11979 pages
741-3.
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER Anglosarcoaa Canes - (Review Date; 1 Jen 1984)
France Sheet 3
Page 7
1 1i
1 1
1J
11 |COUNTRY AND I
| REFERENCE I
| NO
1 1
1 1 France
I 1
1 21
J 1
NAME OR 1 INITIALS I
I 1 1
1
3
DATE OF BIRTH
1 |
1
t1
4 |5
6
1
COMPANY
1
1 | FACTORY
FIRST VC EXPOSURE
1
J 1
1
10 )VP
11
i1 1
1) 1
1
i 1.
11
|L
1 11
i1 1
l1 11
11
11 11 11 11
1
1
11 1
'! I
1
J
I 12 1
11
1 1I
l1 1 li 1
l1
l1 t1
1
1
1
1
l1
1
1J
11 14 | HJ
1
1
1
'( 1 ||
!. 1
124.05.19 RP
1 1
1
1 1X 115.02.12 RP
l 1
l
1 1
1 1
1
1 1 1
1
1 1
1 1
1X
116.08.14 PCUK
1 1 1
1 JI9.01.31
Solvay
1
1 1
l
1 1
1
1
1
1 105-04-24
Ctiioe
1 Chlale
1 ( Formerly
1 RP) 1 l
JX
|St Pone
1 1 1 1
1 |St Fons
1 1 1 1 1 1 1 1
i
l
1 1 1 1 1 l
(Brlgnoud
1 1 1
1 (Tavaux
1 t 1 l 1 1
00.12.56 00.01.41
09.02.49 23.09.63
1
1
1
|St Fone
1
1 1 1
1X
1943
7
DATE OF DIAGNOSIS
1 11
81
9
10 1 1
1 1 ACE AT | DIAGNOSIS |
I l 1
YEARS OF EXPOSURE TO
DIAGNOSIS
1 1 YEARS OF |
EXPOSURE I
DATE OF DEATH
1 1 1
11
11
i
12 1 13 1 14 1
1I
(
11
HISTOI.OCICAL 1 ESTIMATED 1
I
CONFIRMATION EXPOSURE | OCCUPATION 1
LEVEL 1
1
11
11
1l
16
OTHER CAREER HIGHLIGHTS
1 1 1
I | 1 1 1 1
16
OTHER COMMENTS
10.01.78
58 1 21
l
I
1
l
12.08.78
1 1 66 1 37
14
1
1
1
1
1
1
1
1
1
11
1
1
1
1
1
00.05.79 1
65
1
30
1
1
1
X
26.06.79
40
1 1
16
1
1 11
1
1
1 11
1
1
X1
00.07.81 1
57
38
1
1
1
1
_
X Hi Si lan
21 110,01.78 1 i i i i
i 31 111.11.78
1 1 i
i i I t l
i
1
l i l
i
l i 27 123.06.79
1 1 1
ii TTEoOT
i i i I 1 i
i i
I i 36 129.07.81
1
1
1 1 I
Yen Yea
Yei Yaa Yea
1 High |Autoclave 110 yra in
IDied of
(cleaner
I uectianlcal
Ipulaonary
1 (engineering (eubollaa 5
1
llnduatry
Idayu after
1
11946-1956
leurgery
11
1
High
11941-1946 IpolyaerMention
1 1 1
1 i
(general
1
1
Ipurpoae (worker
l 1
1 1
11946-1972 "1
1
IVCH Iayntheele
1 1
1 l
|(I1C1 6
1
1
iAcetylene) 1
1
IForeaan
1
1
I (agent
1
1
|de aaltriae)!
1
11972
1
1
I retired
)
1 1
l 1
11
1
1 High (Monoaer
1
1
(production 1
1
(and polymer- 1
llaatton
1
1 operator
1
1 1 1
IAutocleaner |2 yra aa cyclelCigarette
12 yra.
|aachanlc
laaoker until
(Auto-
110 yra aa
11974. Ill all
(operator
(enaaeller in |of 1977 due to
19 yra.
taanitary war. |Oceophugeal
ICopolyaera |aanufectura (varlcea.
|4 yra
(
I Surgical
11 11
(Intervention I2S.05.79
11
1 (right
11
Ihepatuctoav)
Very High 11943-1975 11975-1979
1
1943-1975 (All typee of(maintenance I
i and
Ijoba on
I work
1
Incerotlcc | manufacture 1
1
eitcly
|6 maintenance
1
J_________1975-1979 11n VCH Poly | 1 Process
;
wi
COUNTRY AND REFERENCE NO
NAME OK INITIALS
DATE OF RUTH
IMPERIAL CHEMICAL INDUSTRIES HI.C PETROCHEMICALS AND PLASTICS l> VISION
LIVER Angluearcoaa Case* - (Review Da e: 1 Jan 1984)
Gernany Sheet I
Page 9
12 13 14
15
FACTORY
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
AGE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
OTHER COMMENTS
01
00.00.30 Dyoaalt
Troledorf 01.10.56 19.09.68
12 12 25.01.69 Yea (NIOSli)
Polyworker
02
00.00.31 Dynaailt
Troladorf 14.10.57 25.09.70
39
13
14.12.71 Yea (NIOSli)
Polyworker
00.00.30 Dynes!t
Rhelnfel- 09.06.52 deo
00.03.73
43
21
16 10.10.73 Yea (NIOSH)
Filling pesticide
1
|Reported under
|non polyiter-
aerosol cans
| laatlon
with VC
(workers in
1NIOSH list of
131.3.77.
(This of course
11 a strictly
| correct.
(However I
(wonder
(whether this
|uan had high
lexpusure tu
IVCH In hie
|cau filling
04
00.00.30
Burg-
16.04.57 26.11.74
44
17
hausen
25.11.74 Yea (NIOSH)
200-500 ppa Polyworker 4 1950 waa
but high
temporary
autocleansr
(operation?
I I
(Clinical
(detalla In
during 1 yr utocleaner for 1 yr
(paper by
autocleaner
ICokel et al
(Virchows Arch
(A Path 1976
(372 p 195-203
l ( 1 k I I 1
seisnan
U:.
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER Angloearcoaa Caeee - (Review Date; I Jan 1984)
Ceraany Sheet 2
Page 10
1 t1 1 1 i |COUNTRY AND | REFERENCE 1 MO 1
(GERMANY
2
NAME OR INITIALS
a
DATE OP BIRTH
l 05
00.00.36
|(NIOSH gives ; |aa Case 06)
1 t 1 1 1
1
l
t 1 |
i|
1
| 06 I I(MIOSH gives |as Case 06) 1 1 1 07 1 1 l 1 1
00.00.32 00.00.26
1 1 } 1 1 | 08
) 1 1 1
I I
00.00.17
6 COMPANY
l1 1 516
11 \l 1 | FIRST VC 1 FACTORY | EXPOSURE
11
11 11 11
lloechftt
Lunze Uscksr Dynaalt
| Frankfurt) 02*04*60
1 i1 il
i1 i1
i1
i1
i i1
i1
i1
i1
i1 i1 il i1 i1
\-
i
i (Ualdehut | 16.12.62
11 l1
1t 11
1 (Burg-
i | 16.04.54
lhausen 1
11 11 11
11 11 11
11 1l 11 1) (Troladorfl
19.07.54
1l
i1 11
l1
7 DATE OF DIAGNOSIS 10.12.73
00.00.75 12.11.75
06.04.75
8 9 10 1 It 12
ACE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF I DATE OF EXPOSURE | DEATH
HISTOLOGICAL CONFIRMATION
38 13 05 116.12.74 Yes (HIOSH)
43
11
12 (09.01.75
Ye*
49
21
21 I13.I1.7S
Yea
(MIOSH
aaya 12)
58
20
20 125.12.75
Ye*
K tS l ltfil
11 13 1 14 |
11
11
ESTIMATED 1
(
EXPOSURE | OCCUPATION (
LEVEL
1 1
1 1
11
11
15
OTHER CAREER HIGHLIGHTS *
I 1 16
1 i I OTHER I COMMENTS
1 1 1 iConflraed
( |
I 1 1 I
1 1 I |
|HC Chant* |
|eaya
|
("chealecry |
(laboratorlan)
tin die (Techno-
( |
(logical
|
(Reeearch
|
(Deparfaent- |
((NIOSII eaya | lasalatanc |
(factory
(
(cAeafat
|
(which aay be|
(wrong
|
(translation)|
1I 1I 11
I|
|PVC - Menu- l
(facture
|
(Shift Leader|
1)
11
1(
(PVC Menu- |
| facture and |
(ell work
|
(loci auto- |
(cleaning
}
112 yre
|
1(1954-66) | fForeaan Tech) (Dev 8 yre 1
1(1967-1975) 1
11
(> 1 lPolywurker |
11
11 1) k1
7
) Reported under)
laon-yolywet- |
lleaclou
|
(uorkeru in
|
(NIOSH List of | 131.3.77 and |
11.78. 1 don't{
(think this ia |
la correct
|
Iclaualflent Ion)
(by NlUSH. The| Ivan Bay have )
(been involved (
tin VCM
|
1polyaeriaaclon]
iin pilot pi ant|
lor In aaln
|
Iplant.
|
11
11 1I 1t
1I 1I 1I 1( 11 1( 1I 1( 11 11 >1
11 1I
1I )l 11 11 11 11 11
COUNTRY AND REFERENCE NO
NAME OR INITIALS
DATE OF BIRTH
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AMI) PLASTICS DIVISION
LIVER Angiosarcoma Cases - (Review Date: I Jan 1984)
Cerasny Sheet I
Page 11
12 13
15
FACTORY
FIRST VC EXPOSURE
DATE OP DIAGNOSIS
AGE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
OTHER COMMENTS
09
11 1 10 | | (NIOSli given! | as Case 11) | 11 !1 11 11 Ii 11 11 1 11 \
(NIOSH give as Cave 10)
00.00.34
Marl
20.02.61 16.06.76
41
15
13 24.03.78
Hlgli peaks
12 yre polywocker loci I7Z auto clave cleaning
Control roots 1 yr
1 100.00.36
1 1 1 1 1 1 1
1 1 100.00.29
CUII Wacker
1 IMarl
1 1 1 1 1 1 1 1 1 I Burg-
hausen
1 1 01.01.61 1 1 1 1 1 1 1 \ 1 1 10.10.55
00.01.77
1 1 1 I 1 1 1 1 1
1 28.06.77 l
40 16
____
47 21
00.00.38 Dynastt
Trolsdorf 00.00.61 OQ.IO.77
39
16
I 1I 1 10 107.03.77 1 1 11
1 11
1 11 11 1 11
1 11 1 11 1 11 1 11 1 22 128.06.77 1
Yea Yea
07.10.77
1I
1
(High peaks 110 yrs poly-]
1 (worker Incl 1 1 |17S sutu- |
1
(clave
|
1
Icleanlng
|
1I
>
11
1
11
1
11
i
1 1 High
11 |3 yrs auto- |
clave
cleaner
19 yra
filter
operecor
PVC Manu facture Autoclave worker for 6 yre
10/78 Con f 1 riaed
Average exposure flrei 9 yre ISO ppa occ 1000 pp<a, Next 3 yre av
75 p|xa. Last yr av 35 ppm
1 (Average
1 1
(exposure first!
|9 yrs 150 ppal
(occ 1000 ppa.l
(Luut yr av
(
17 5 ppa. CWH |
I letter of (21.04.78
| |
1(
11
11
oks nan
1
COUNTRY AND REFERENCE NO If
NAME OR INITIALS
DATE OF BIRTH
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS ANl> PLASTICS D VISION
LIVER Angiosarcoma Cases - (Review Da e: 1 Jan 1984)
8 10
FIRST VC EXPOSURE
DATE OP DIAGNOSIS
ACE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF HISTOLOGICAL
DEATH
CONFIRMATION
13
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
Ceruany Sheet 4
15 OTHER CAREER HIGHLIGHTS
Page 12
16 OTHER COMMENTS
00.00.14
Waldshut 00.00.60 OB .04.78
63
19.05.78
14
15 (NIOSN gives this as Case 13)
16
00.00.29 Uacker
Burghausen 19.10.53 09.10.78
Not an Anglosarcoaa la his letter of 21 12 81. Hr Frledel
aald thia was a 'Platteneplthelkaralnoa Der Spelserohre" (a carclnoaa of the oesophagus) not attribut able to VCH 4 not recognlaed aa an Indust rial disease
25
25 23.10.78
Yes
Autoclave cleaner and worker. Drier operator. Later shift leader
00.00.23 Dynaalt
Troiadorf 10.01.55 07.08.78
55
23
20 07.08.78
Yce
High
Autoclave
(Lelbacb
ASL and
worker till
suapected
llepatocel lular
1964.
ASL at
Carclnoaa
Leader and
Feb 1975
waster
laparotoay)
ins nan
F W Beat letter of 30th June 1980 enclosing data t rua Mr H P Frledcl of BG Cheale F U Best letter of 30cIt June 19BO enclosing data f row II P Frledcl of BG Cheale withdrawing thia case
Angiosarcoma coufiraed 09/79. Some detail of this 6 also esses 9. 13. 15, 16 6 17 given In NEW Report for 1978 Rngloearcoaa confIraed, full details of Illness since March 1973 given In NKU Med Insp Rep for 1978. Different details given tu "VC Associated Disease" by l.elbach and Hiirstcller (198 1) yl 1.
IMPERIAL CHEMICAL INDUSTKJES n.C PETROCHEMICALS AN/) PLASTICS DIVISION
LIVER Anglosarcoasa Cases - (Review Date: 1 Jan 1984)
Cernaity Sheet 5
Page 1)
10 II 12 13 14
15
16
COUNTRY AND REFERENCE NO
NAME OR INITIALS
DATE OP BIRTH
FACTORY
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
ACE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
OTHER COMMENTS
CERHANY 17
(NIOSH gives as Case 15)
18 19 20 21 22
00.00.37 Dynanlt
Troledorf 01.11.61 14.08.78
16 28.08.78
00.00.13 Hoechet
Cendorf
00.00.55 25.12.79
66
24
25.12.79
High
Autoclave worker
Autoclave Worker
No Anglosarcons confirmed. Annual report of Cite North Rhine Westphalia Medical Inspectorate fur 1978 pages 347-377 gives full details. Vinyl chloride dlaease diagnosed 02-02-73. Oesophageal varices. Radlolugically confirmed acru osteolysis.
00.00.25 Dynanlt
Troledorf ia.io.54 00.08.79
54
25
18 22.02.80
Yes
High
Autoclave
Mscastaslng
Worker
ASL
Dr Reache letter of 13-04-82 to Dr W C F Adams
00.00.15 Dynanlt
Troledorf 14.02.61 00.04.80
65
19
13 19.10.80
Yes
High
Autoclave
Haenanglo
Worker
Cndothellona
of liver with
Hecaataeee
Dr Besche letter of 13-04-82 to Dr W G F Adana
00.00.11 Dynanlt
Troledorf
01.01.62
00.09.79 pronounced clinical 1 Iver ystoaa)
66
13 19.06.80
Yes
Haeeanglo
Endotheltona
of liver with
Hetastesee
High
Autoclave Worker and worked in drying shop
Dr Besche letter of 13-04-82 to Ur W C K Adana
00.00.21 Dynanlt
Troledorf 15.10.61 17-09-80
59
18
06.12.81
Yes Hetastaelng ASL
High
Aotoclave Worker
Chargehand, subsequently Fotenau
Dr BeBche letter of 13-04-82 to Dr W C F Adams
ms nan
I
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS ANU PLASTICS DIVISION
LIVER Angiosarcoma Cases - (Review Date; i dan 1984)
* Should title case be removed from the list? NIOSH have It uu their supplementary list relating tu non-polymerleaClon workers expose<
to VCW.
Page 14
JS 1/8/77
j'
1 12
1 13
1 k----- 51--------------- 1
1 1
1COUNTRY ANU | NAME OK | DATE OF
t REFERENCE t INITIALS I BIRTH
I NO
1
1
1 ITALY
1 I
1 1
4 COMPANY
1 |5
1 1 1 ! FACTORY
I 1 1
111
6|7
al
9
1 10 1 11
J1
l1
1
FIRST VC 1 DATE OF 1 ACE AT l YEARS OF
YEARS OF | DATE OF
EXPOSURE I DIACNUSIS 1 DIAGNOSIS I EXPOSURE TO l EXPOSURE I DEATH
1
1 DIAGNOSIS
1
\1 1 1
11
1 1
11i 12 | 13 1 14 |
11 1
11
1
HISTOLOGICAL | ESTIMATED 1
1
CONFIRMATION ( EXPOSURE 1 OCCUPATION I
| LEVEL 1
1
1
11
15
OTHER CAREER HIGHLIGHTS
1 i 1
| I 1 1 1
16
OTHER COMMENTS
1 oi |(On N10SH | supple| nentary 1 list)
I 02
| 03
| 04
| LG
i
i i
i
i
i
i
i |SK
1
1
1 |VC
1
1
1 1
1 1 |fu
1 l 1 l 1 l 1 1 1 1
115.06.34 PANSAC
1
00.00.65 I 19.04.71
36 1 06
i 11
1
i 11
1
i 11
1
i 11
1
i 1i
1
i 11
1
i 1I
1
i 11
1
113.11.29 Montedison)Porto
00.00.57 1 13.12.72
43 1 15
1
(Marghera
1
1
1 t1
1
1 114.03.20
Solway
1 1Fetrara
l 00.01.53 I 10.07.75
1
55 1 22
1 11
1
1 11
1
1 11
1
1 l1
1
1
1
120.07.37 ANIC
1 1 1 1 1 1 1 1 1 11
11
1
I1
1
|Ravenna
00.04.59 I 00.01.81
43 1 21
11
1
11
1
11
1
11
1
11
1
1 111
11
1
11
1
1
1
11
1
1 111
03 116.04.71
? Yee
1
1
1
l
1
1
1
1 06 127.12.72
Yes
1
1 21 110.07.75
Yss
1
1
1
1
1
1
21 130.03.81
1 1 1 1 1 1 1 1 1 k 11
Yss
|
JPVC 08*
1
|Primary turnoutl
i
(extruder
|
(may have been
i1
1
(pericardium.
i1 i1
1 1
(Not homo(geneous with
i1 l1
1 1
(other cases.
| ft* AAA
iI
1
1
i1
1
| |Polyworker |
11
1
1 [A*
| ** A
11
1
i
11
1
1
| High
1 1
lAutocleanet | |6 yrs (1953-) |6I) Autoclave
1972-5 did 1
a variety of|
Jobs
|
AAA
1
(operator
| Including 1
1 112 yrs (1961- PVC packing 1
1
172)
1
11
l
1
| 12 yrs - 11 yr -
< Very High (Monomer
1 1 5 yrs ) Medium
(operator
I J20 yre -
|Never cleaned 1
(autoclave*. |See paper by
1|
AAA
ICHIAPPINO et |Non-snaker.
|al Med Lavoro (Consumed
1 1 4 yrs -
I Lou
1 1 1
(Autoclave |Vol 6 (19112)
(operator 4 |pp 555-563
(other ducieal
(In euepene- |
(ion polymer-!
(Isaclon.
|
(little
(alcohol.
| AOL. 1 ) (
No
1
I **
l1
11
1
1
1
11
11
1
I1
1 1i1
11
11
1
11
1 111
05
|C Danesln 119.03.37 Pansac
I Hits
00.00.67 | 07.03.83
46 1 16
11
(Venice 1
1
1
1
11
11
1
11
1 111
11
11
1
J J _L
1 J.
1
f J_
1 1 1
1 1 a 106.04.83
1 1
1
1 1X
see Haltonl Med ill Lavaca 65 p445, 1974. Further details In lettef from Ur Montesano of 1AHC on April lac 1962.
Yes
1 1 1
1 1
1 Medium-?
(Are* Foretank
(In same Depcl (since (975. |
11
11 (Bag extruderl
Illlgh
1 1 1
(1967-1975 | Commercial (Dept 197611983
|
| |
|
!______________J___1 _______________
\
I 1 1 1
IS Psglla-
(lunge telex of|
(2 Aug 1981
1 1
J
*** Aleo aee Maltonl and Rondlnella in Acta Oncologies Vol 1 1980 pages 35 - 49. (IC1 has made a translation of this paper Into English and copies of the translation can be made available on request).
eHS nan
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER Anglosarcona Cases - (Review Date: 1 Jen 1984)
'15
{1
> 4>`
12
i31
11
11
{COUNTRY AND | NAME OR { DATE OP 1
| REFERENCE I INITIALS I ttIRTH |
4 COMPANY
1 |5
1 1 1 | FACTORY
6
FIRST VC EXPOSURE
1 NO
11
1
{JAPAN 1 oi
{Toeoji IHorl
1 \ _|
11
1
i1
1
11 101.08.22 |Mitsui
1 {Nagoya
1
ITostau
1
1 |(no coaaent|
i |by Jap PVC 1
i
\Aaboc)
1
00.04.53
i1
1
i(
1
i1 it
1 {
i1
1
iI i1
1 1
l 02
ISO
i{ 102.08.39
l 1 00.11.58
11 i1
1 1
1I
1
t1
1
1J
_!
78
DATE OF DIAGNOSIS
ACE AT DIAGNOSIS
24.10.75
* 53
10.08.7b
37
9 YEARS OF EXPOSURE TO DIAGNOSIS
* 22
17
10 11
YEARS OF EXPOSURE
OATE OF DEATH
13 24.10.75
13 10.08.7b
11 12 1 13 ) >4
11
11 HISTOLOGICAL I ESTIMATED I CONFIRMATION I EXPOSURE | OCCUPATION
1 LEVEL 1 11 11
11
{|
Yea {PVC Assoc 113 yre auto-
Isays not {clave
{known.
{cleaner
I* Japan 1 Tinea
11964 {assigned to
{indicated {different
|on 25.l0.75|work since
lesposures {tied 111 {often st {health
{3000 ppa uPi
Ito 1974
1
11
1{ Yea {Not known (In polyner-
1 {leatlon work 1 |Including
1 lautoclava 1 {cleaning
J____________ Jl
15
OTHER CAREER HIGHLIGHTS
1 1 16 1 l { OTHER | COMMENTS
1 1 1 1 | IJapun Tines 125.10.75 6 {Japanese PVC {Assoc letter |uf 31.03.78
1 1 1 1 1 1 1 1 IJapanese PVC {Association {letter of 131.03.78
l 1
In his le ter of 1st April 1982 Dr Honteeano of IARC says Japanese Ministry of Labour give
bate of diagnosis Age of disgnoais Years of exposure
21-08-74 52 22
msi nan
COUNTRY AND REFERENCE NO
NAME OR INITIALS
DATE OF RUTH
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER Angioaarcoma Caaee - (Review Dates 1 Jan 19^4)
Page 16
10 II
13 14
16
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
AGE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER
CAREER HICHL1CHTS
16
OTUEK COMMENTS
01 AH
23,12.16 Norsk
lleroya
00.03.60 21.12.71
56
22
21 04.01.72
Hydro
High
Foreman 4 Au toclave eupervlaar
Confirmed by Dr Tillin' Evansen of Nil.
At APHE Htg of 9 June 197U Mr H Rungnea etaced dial All Dad been a
member of a atart-up team. VCH i PVC were made In aame building. 11le VCH waa made from acetylene
shsi ian
IHPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS I) VISION
LIVER Angloaarcoaa Cased - (Review Da
l Jan 1984)
Page 17
l 2 3 4 56
COUNTRY AND REFERENCE HO
NAME OR INITIALS
DATE OP BIRTIl
COMPANY
FACTORY
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
ACE AT DIAGNOSIS
SWEDEN 01
I 02
NU
) IBL 1
23.06.27 Keaenord Sundsval1 14.08.51 20.10.70
l1 127.11 11 ) Rewanard
11
11
i *\
|Sundavall{ 00.01.4S | OO.Oti.72 (
11
1
1
43 61
i
1
9
YEARS OF EXPOSURE TO
DIACNUSIS
19 '
10 11
YEARS OF EXPOSURE
DATE OF DEATH
IB 20.10.70
12 HISTOLOGICAL CONFIRMATION
Yes
13
ESTIMATED EXPOSURE
LEVEL
14 | OCCUPATION |
15
OTHER CAREER HIGHLIGHTS
1
I 1 1 1 l 1 1 1
1 Polyworker |
1
16
OTHER COMMENTS
1
1
11
1
27
1 27 116 08.72
Yea
1 High
1VCH
1
11
1 (product Inn 1
1 |Hr SJoelln'n (letter of
28 March 1978 conflraa EL was a aouower worker who was heavily eK|K>ee J, probably even wore so Chun a iionaal reactor cleaner
03 (ME
1 1 04 | AL
1 1 1 1 1 1
(10.06.10
( J 116.11.14
( l l 1 1 (
Keaanord Keasnord
ISundavalK 00.05.47
1I t1 |Sundavall) 00.00.46
11 l1 11 (1 11 11
18.03.76 12.05.77
(
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1 | 1 ( 1 1 1 (
65 62
29
21 119.03.76 (
Yes
t High
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! t1
11
1
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31 112.05.77 (
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(1946-1958 1
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11
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1 (1977 foreasnl
l Ii
1
1(19 yre)
1
1
1 I | In first 12 lyre of leaployaent (been hesvll leapouod. 1 (1974. liver |abuoraalIty
and necrosis diagnosed. Data confirmed In Dr D Hyreii letter 18.8.77 Co CERIC
05
12.03.19 Kewanord Sundavall) 1 .05.64 22.11.80
61
6
16 22.11.80
Yaa
High -
1964-1970
6 Years
centrifuge
Low -
operator
10 Yeara 1970-198U
drier
9Hsnan
letter of 2nd Nov 1981 f row
Dr David Byren
* In hie letter of 1st April 1982. Dr Monteaano of IAKC says In Sweden's National Board of OS Health gives 20-02-70 as date of diagnosis for Case 01 and 15-05-72 for Case 02
IMPERIAL CHEMICAL INDUSTRIES PLO PETROCHEMICALS AND PLASTICS DIVISION
LIVER Anglosarcoaa Cases - (Review Dacei 1 Jan 1984)
UK Sheet I
Page lft
1 12
1 13
11
l1 COUNTRY AND | NAME OR ( DATE OF
REFERENCE | INITIALS | BIRTH
NO 1
1
11
11
UR 1
1
01 |UJ
1 1 i l 1 1
1 1 1 02 1 1 1 1 03 | HJU
1 1 1 1 04 | JSK
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i i i
i i i i i i i i
i i 102.0ft.37
1 1 1 |23.Oft.20
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11 1 51
6
11
11 FIRST VC
| FACTORY | EXPOSURE
!' i
OATE OF DIAGNOSIS
ft
ACC AT DIAGNOSIS
ii ii
ICI
BP ICI
|HIXIhouse|
ii ii ii ii ii it ii ii
04.04.44
03.12.72
(Fox ft Collier paper aaya| 23.12.72)
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ii
ii
ii
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l |Barry
l 1 00.02.6b
00.12.74
11
11
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11
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11 1I
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11 11 11
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11 11
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11
11
11 11
11
11
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71
37 59
9
YEARS OF EXPOSURE TO
DIAGNOSIS
1 10 1 11
1 1 YEARS OF | DATE OF EXPOSURE ) DEATH
1 1 1
1
12
HISTOLOGICAL CONFIRMATION
I1 13 1 14 1
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11
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1
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LEVEL 1
I
11
1J
11
>5
OTHER CAREER lltCHLICHTS
l 1
1 1 | (
k
1 1 1
lb
OTHER COMMENTS
2tt 22 09 3.5 25 IS
^ is nan
103.12.72 I ( For ft (Collier Ipaper |uaya 123.12.72))
1J 1 1 1 1 1
1 1 124.12.74
1 1 \ l 112.10.79
1 1 1 1 1 1 1 1 l 1 1 1 1 1 1 l 1
1 1 1 1 1 1
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Yes Yes
\ 500 ppa 11944-7 VCN 1 11947-8 Drier!
|l^e anJ Harry ]Lancet
1194ft-ftl |Autoclave
k k
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(operator 11961-66
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j
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i
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COUNTRY AND REFERENCE
NAME OR INITIALS
DATE OP BIRTH
OS 30.03.14
06 CEP
1931
07 26.04.20 BP
08 08.05.24
Barry
Barry Barry Barry
PIRST VC EXPOSURE OS.01.SI
1962 1963 19.09.SO
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
UK Sheet 2
Page 19
LIVER Anglokaicoaa Caae^ - (Review Date: I Jan 1984)
DATE OF DIAGNOSIS 00.10.79
09.01.BO 00.00.BO 27.11.81
ACE AT DIAGNOSIS
48/9 60 57
10 1 11 1
11
YEARS OP
YEARS OP | DATS OP |
EXPOSURE TO EXPOSURE I DEATH 1
DIAGNOSIS
11
11
2 a 21 (19.11.79 1
11
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1
11
11
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11
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| 13
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1
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I HIGHLIGHTS 1
i1
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1
11951-52
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1 1 I 1 1 1 1
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11960-64
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11964-70
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1
11963-5
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11968-1974 1200 ppa
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11957-1974
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1 ( 1 1 1 1 ( 1 ( 1 l 1 1 1 l 1 1 1 J
11
1
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16
OTHER COMMENTS
t a ^'is
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IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER Anglusarcoaa Cases - (Review Date; 1 Jan 1984)
*UK aystea of dates DAY - MONTH - YEAR
USA Sheet 1
Page 21
1 1i
1 12
1 13
1 11
l 1t
I COUNTRY AND | NAME OR | DATE OF
l REFERENCE | INITIALS | BIRTH
1 NO
1
1
1 1>
11
(USA
1
1
11
1 01 (Earl
117.10.23
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|
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1 11 i t1
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|
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11 11
i 11
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1 villa
1 1 1 1
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I villa
I
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1
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| vllle
BFG UCC
1 1 I Louis-
I villa
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1
1 1
J
6 FIRST VC EXPOSURE
09.12.48
I5.1I.SS
28.11.45 06.07.S2 19.06.44 17.01.62
27.08.44 07.10.46
11
1 11
7 | a 1 9 1 10 1 U 1 12
11
I 11
11
1 11
DATE OF | AGE AT 1 YEARS OF 1 YEARS OF | DATE OF | UISTOMXjICAL
DIAGNOSIS | DIAGNOSIS | EXPOSURE TO | EXPOSURE | DEATH | CONFIRMATION
i
1 D1ACNOSIS 1
11
1 _1_ 11
1 11 1 11
11
1 11
11
03.03.73 |
49
1
24
1 1t 1 21 103.03.73 |
Yes
11
1 11
11
l 11
11
1 11
11
1 11
11
1 11
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00.05.70 |
37
1
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1 11 1 13 I27.U9.7I |
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11
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|
11
1 128.09.71)1
1 1 _!_ t 1
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19.12.73 i
58
1
28
i 1I i 28 119.12.73 |
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11
t 11
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43
1
15
i 11 i 15 107.01.68 |
Yes
1
11
i 11
11
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1
11
1 11
09.04.64 |
52
1
20
1 20 109.04.64 |
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45
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1
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11 11
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1
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11
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I 11
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1
00.08.61
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|
41
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1
15
i 11 l 11
i 15 129.08.61 |
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11
l 11
11
t 11
11
I 11
1 J_
11
1 13 |
1 1 ESTIMATED I
1 14 t
IS
1 1 | OTHER
1 1 16 1
1 | OTHER
EXPOSURE LEVEL
| OCCUPATION |
CAREER
| COMMENTS
1 | HIOHLICHTS 1
11
1
11
1
1 IHlsLory given IKolllng Stone
1 1 In Anoxia NY lArc
|Pot Cleaner |ACAD SCIENCES |Kef 1 NY Acad
((Block Jama |Vol 329 (1979) |of Sc Syap
I 1974) p 53 Ipage 190 in 11974
1
1 Paper by
(Also Block
1- |B It Gottlne of|Juna 1.7.74
1
IGSIU
Ip 53
11 11 IPot Cleaner | |<Cf Block) |
11 11 11 11 |Pot Cleaner ILoulavllle
|(Cf Block) (Courier 1 iJournal 1 102-09-80
1 1 IKef 1
|Also Block iJama 1.7.74
ip 53 1 1 | Kef 1 |Also Block
1
11 |Pot Cleaner 1
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|(Cf Block) 1
1
1 |Kef 1 (Also Block
11
11 |US Air Force)
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1 1 Kef 1
11 |Pot Cleaner |
|(Cf Block) |
I Louisville IT1MS 23.7.75 |RetireJ April
1l 11
1 1974 |Also Block
11
11 1|
1
1 IKef 1
1I 11 11 11
11 11 !1
1 1 1 IKef 1
1 1
1 1
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Si COUNTRY AND
REFERENCE NO
NAME OR INITIALS
DATE OF BIRTH
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS U VISION
LIVER Angloaarcoaa Cases - (Review Da e; I Jan 1984)
*UK ayatea of dates DAY - MONTH - YEAR
USA SheeC 2
Page 22
10 12
14
FACTORY
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
ACE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER ''career
HIClILlCHTS
16
OTHER COMMENTS
09
Raynond
0b.ii.3i
RFC
Gettle-
Finger?
Loulavllle
26.05.45 01.03.74
43
10
tt.oa.13 Coodyear Niagara
12.06.51 00.05.68
27.05.09 Goodyear Niagara
1 A.10.46 00.03.70
12 Francis A 17,11.18 Bachaan
Potcatown 13.07.49 Pa
02.05.69
61 50
I)
Richard
01.12.21
UCC
Edward
Clendenin
S Charle ston
11.12.42
00.05.74
52
29 24 11.01.75
2000 ppn
Ref I has wrong figuret re first exposure. Louisville Tines 29.10.74, 12.3.75, 10.3.76
10.05.68
Kef 1
23
23 16.03.70
Yea
Ref 1
19 02.05.69
Yea
High 10 yrs 10 yre as
Utility &
reactor op. Service up.
(not cleaner Bagger
- separata Dryer op.
crew cleaned Stripping op.
autoclaves) 3 yre prior
service in
tyre plant
Ref 1 + letter of 26 April 1978 frua Russell A Park to .1 T Seawel 1 of MCA
32
07.04.74
2000 ppa
Charleston Daily Mall 21.7.75
Dubious fabrication case
Dubious fabrication case
t
t/jitii- nan
COUNTRY AND REFERENCE NO
NAME OR INITIALS
DATE OF BIRTH
IMPERIAL CHEHICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS l> VISION
LIVER Angtoearcoue Canes - (Review Da e; 1 Jan 1984)
UK Syatea of daces DAY - MONTH - YEAR
USA Sheet J
Page 2)
10 11
15
FACTORY
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
ACE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER
1
1 1 j
HIGHLIGHTS |
OTHER COMMENTS
Janes Howard
04.11.27
Pearenbooi 06.05.31
Charlie Arthur
22.04.28
Louis ville
OB .05.50 00.00.b9
41
Louis ville
23.06.55 11.10.74
43
15.09.54 00.00.75
46
Virgil
00.00.15
Christian
S Charle 00.00.43 ston
19.06.75
60
31.08.17 Coudyear Niagara
00.00.55 30.01.76
Cltester Hinkle
02.09.09 UCC
S Charle 00.12.46 ston
Early 77
58
19 27.03.69
1951-4 VCM Frou 1954
|Table 4 in
polyner-
onwards In lWagoner
isat ion
Amy and other|Testinony to
servlcs.
|US Senate
46-50 Amy
IConflrned In
|H N Johnson
lltr 07.08.7S
Yee 19 19 16.10.80 on 11.10.74
I
I |Ur H N Johnson
but no
|letter of
poat-aorten
124.2.81 con-
16.10.60
|fired death
|6 years after
Idlagnoala
.21
13 02.11.75
Yes
13 yre
Navy
I IConflrned in
autocleauer 8 yra on
|H N Johnson lltr 07.08.78
Sacol
Tyre Store
| Also Rolling
plasticiser
(Stone nag.
6 Carboeet
115.01.76
operation
I
I
32
06.04.76
2000 pp
I IWllllaasport
|Sun Gsautte
12 I June 1975
|Charleston
I Daily Mall
121.7.75
21 18 30.01.76 30 22 02.01.77
I INIOSH letter lot 25.10.79
I 1 12B yra with |UCC at SC |Retired (News release
123.2.77 I
ssisnan
IMFEKIAL CHEMICAL INDUSTRIES PLC
USA
Page 24
PETROCHEMICALS ANO PLASTICS U VISION
Sheet 4
t *UK system of daces
LIVES Angiosarcoma Cases - < Review Da e; 1 Jan 1904)
DAY - MONTH - YEAR
11
1
12
13
1 J___
11 |COUNTRY ANO | NAME OR | DATE OF
REFERENCE | INITIALS | BIRTH
NO 1 1
1
J
(USA
1
1
11
11
1 11
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1
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1
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11 11
1 Ji 1
1 11
1
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1 FIRST VC
DATE OF | ACE AT 1 YEARS OF
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|
COMPANY, I FACTORY | EXPOSURE 11
DIAGNOSIS | DIAGNOSIS | EXPOSURE TO 1 EXPOSURE k DEATH I CONFIRMATION | EXPOSURE I OCCUPATION (
1 1 DIAGNOSIS
11
j LEVEL J
|
1(
L1
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1
1
1*
11
11
1l
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15
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1 (
| 1 1 ( 1
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| i 1 i l
22 | 1
102.10.23 1
BFG
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| 11.07.47 |
00.01.76 | 1
92
11
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|
1
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24
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117.03.17 UCC
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27.05.77 |
60
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1 1 1 1 1 1 1 1 1 k 1 1 1 1 1 1 1 1 1 i
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1 28 J04.12.76 | ii ii ii ii ii ii ii ii AI
il 1I Ii i 1i Il ll Ii I> li
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106.04.73 |
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11 11 11 |27 .OS.77 ICliotanglo| jHircuiA I |(R Kaminski
1 1
t
1 1 1 1 1 1 1
1 1 1 1 1 i i i i I i t l I Med1 urn to (high for |24 yrs
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11 11 11 11
11
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11 11
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|
||
11
II941-65 non- 11937-39 was
(solvent
|off and on
(vinyl reain 1 labourer
1 |Loulsvllla
l |
(Times 26.1.76 |
(said he was |
I the IOcIi AS I
(victim at
|
|Bells Lane of |
|whom 0 had
|
(died by
|
(26.1.76
k
|In his letter |
(of 16.09.81 t |Dr M N Johnson|
(confirms tikis |
|1b the
|
lease described)
| by Oannuher |
ITsmburro 6 Yam)
|in Feb 1900 |
(Am J Medicine | 1Vol 70 n2HO 1
||
|
1 |N H Wheeler lletter of 118.0.77 to
|
1 | | (
11 I1
ti
1
11 11 1I
1l 1l 1i 1I
|
I 26/2/79)
1
11
l
11
1
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(unit and
11939-41 may
(dispersion (have been
(vinyl realnaleaposed as
lunlt first (reactor
(J Stafford
|
laIves decalls 1
(Rose Kaminski |
lletter of
|
(25)
1 1 1 1 1 1 1 I l 1 1 1 1 1 1 1 1
1 11
11
1 11 1 11
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1 11
11
1 11
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1 11
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1 11
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1 11 J 11
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126/2/79
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|ft Kaminski
|
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(utility men 11946 became
(suggests that 1
1
(shift utility i NIOSli will
|
k
I4ifk
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|
I
(26.04.65
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1
|terminated
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i1 Is
l1
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1R N Wheeler |
| letter of
|
l1 Il
120/2/79 aiwl | (Rose Kaminski |
mmi____________________
1 * 1
IHHtlUAI. aiKHICAL INDUSTRIES VLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER Anglosarcoua Cases - (Review Date: I Jan 1904)
*UK system of daces DAY - MONTH - YEAR
USA Sheet 5
ease 25
1 11
t (COUNTRY AND (
REFERENCE (
NO 1
(USA el
)
1 2|
t NAME OR |
INITIALS t
I 1
3
DATE OF BIRTH
26 IJoliu Berrytt)7G7*2)
ii
ii ti
ii
ii
ii
ii
(i tt
ti
ii ii
ti
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27 ITT
i
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| Forrest |
20 29 30 WVN
11.04.17 12.10.07 22.07.22
31 08.11.23
4 COMPANY
11 151
6
11 1 1 FIRST VC ( FACTORY | EXPOSURE
11
i1
DATE OF DIAGNOSIS
BFG UCC
ILoula- | 03.10.47
(villa
|
11 11
I1
11
11 11
1k
(1
11
1I k1
11
1-1
j S Charl-| Cl.07.41
) StOD |
00.00.77 (up to 2 yearn after deat h)
l
30.11.78
S Charle 00.00.44 ston
03.II.78
S Charle 00.OS.42 ston
00.03.00
Tenneco Chemical*
Flealngton 11.06.64
30.12.00
S Charle ston
12.05.46
01.00.81
1
61
ACE AT
1 |
DIAGNOSIS |
1
1
9
YEARS OF EXPOSURE TO
DIAGNOSIS
52 (death)
(.2
l |
1 1 1
1 ( 1
1 1 1
1 1
l 1
| 1
28 (death)
37
61 34 72 30 58 17
35
1 10 1 11
1 YEARS OF | DATE OF
11
12
1 13
1
11 HISTOLOGICAL I ESTIMATED 1
1
14 |
|5
i 1 OTHER
1
1 16 1 | OTHER
|
EXPOSURE | DEATH 1 CONFIRMATION ( EXPOSURE | OCCUPATION |
CAREER
| COMMENTS
\
1 LEVEL 1
1 HIGHLIGHTS (
1
11
I
1
- 18
(11.02.75
1 1 1
YeB
11 lEvpoaed In IVarlous Jobs!
(some degreelln PVC
1
|co 22
(plants from |
(chemicals (cold roue to)
| |K Kauliiflkl (letter of
(26/2/79 and 1 Prof. Taaburru)
1
(but stain (paste
1
|letter of
1
(exposure (recovery to (
(9/1/79
1
(was to VCM (PVC charglngl
1
1
Iprobably {operator Co |
1
1
(high
(paste
|
1
1
1 (charging. (
l
1
1 (111 August |
1
1
1
1>965.
1
1
1
1 (Terminated |
1
1
1 (employment |
1
1
1
(Jan 1966
1
1
20 l25.ll.7f
Yes
I
digh
(Operator to (Exposure In
|R N Uheelcr
( NlOSti
1
1
110.(0.76 (bulk end
(let of 4 Jan
says 27
dispersion PVC 1971 and
and C
manufacture
Charleston
Dally Hall
Dally Hall
2 5) 30.11.70 and
k Kaalnskl
33 03.11.70
26/2/79 K Kaalnskl
letter of
01.03.00
6/4/79 ft Kualnskl
Letters of
19th Joe 1900
30.12.80
(6 - Unknown Maintenance
A 5ch Now 1980
|9 - Klnlaal Mechanic
I 6 yra I Elaewhere
I) yrs
Boiler house
Operator
02.04.82
I High (But
9 yrs Chealcal
Proa 1959 to Dr Dacey
(not as high Operator in 1976 Aliphatic letter
|as reactor charge
Cliealcal a
(6.10.01 and
(cleaner
reactor
operatur and K N Wliecler
(would
from July 1976 letter of
(experience) |Worked ss I labourer (f roa
ro date Foreman Aliphatic chealcal
9.II.81. Also Dr Decay letter of U7.03.U3 re
(June 1941 (to Hay 1946
Operation
dace of death.
(and aay
(have
itjn
| cleaned (reactors In
(that llee
IMPERIAL CHEMICAL INDUSfKrES LIMITED PLASTICS DIVISION
LIVER Angiosarcoma Cades - (Review Dace; 1 Jan I9B4)
USA Sheet 6
*UK system of date DAY - MONTH - YEAR
Page 26
COUNTRY AMD REFERENCE NO
HANK OR INITIALS
DATE OF BIRTH
US 32
C H Giroux 22-02-08
US 33
S Fergueun 08-10-27 Jnr
|51 6
11
11 1 1 FIRST VC | FACTORY I EXPOSURE
11 1i
11
Springfield 15-10-51
| Haaa
|
i1 11 11
I1
11 11
11
(f
t1 11
11 11
1I
11 |1
1t 11 11 (Louisville
0
1C 1
V**
DATE OP DIAGNOSIS 00-07-79
1 1-05-82
8 AGE AT DIAGNOSIS
71
54
US 34 US 3S US 36
Mr Uyrum
|(29-01-34
UPC
(Louiavllle
11
1
11
l1
\ Ji .... |t t
(09-03-12 (ICC
1|
1 1
1 |S Chari e -1 leton
11
1
11
( J
1
-
1t
1
127-08-32 (Tire GeneraliAshtab
1 (Tire end |Ula 1 (Rubber Co |
11
1
(1
1
14
1
1(
1
1l
1
1955 23-07-44 1-06-56
| 03-11-82 ( (
1
1 I 18-U7-83
1
1
1
1
121-08-83
1 1 ( 4 1
4
1
1
1
1
1
f
1
1
1
1
1
! (
l
4 l 4
I
1 1 4
48 61 50
9 10
YEARS OP EXPOSURE It)
DIAGNOSIS
YEARS OF EXPOSURE
28 14 (in FVC autoclave area)
p
26 28
27 4 10
1
4
1
1
1 39 14
1
1
1
!
1
27 1 27
4 4 4 4 4 1 4
l j I-
|
11 1
12
13 ( 14
I 15 I 16
1 1 DATE OF | HISTOLOGICAL DEATH | CONFIRMATION
1
1 ESTIMATED ( EXPOSURE | OCCUPATION
OTHER CAREER
J______________________ I I OTHER | COMMENTS
1
J
1 17-05-80 | An autopay
| waa done and
LEVEL
I 1
The death 11940-1951 Certlflcate|Varloue Jobs
HIGHLIGHTS
I
J_____________
I I Information
(given in
| Immediate
gave
(la polymer
llettur of 24
| cauue of
Hr ClrouR* (manufacture
(February 1982
| death given usual
IUUTVAK
1 **
occupation ILUSTKKX
I"Angiosarcoma" aa "Lett 1*11951-1964
(from Dr (Ualter C (Barnea of
1 operator* IVarloue Jobe 1 In (In and 1 "chemicals latound PVC 1 lnduatry*. (autuclavee
1 11964-1973 1 (Variouu 1 (clerical 1 | )oba in PVC
|Hunaantu |Springfield to |Dr A Munn of |Muneanto I Europe
I I i
Alive
1
4
t
J4
] Yea
|polymer leatIon (facility/ 1 Retired 101-03-73. 1 multiple
I 4 l
J_______________
I Prof Taaburro
Jobs
(letter of
Including Foty
|I2 Aug 1982 + |Ur H N Johnson
Operator
lletcer of
Polycleaner.
|28 Feb 1983.
I Alive
1
4
1
1
4
(18-07-83
1
1
4
4
1
(Alive
1 4 1 1 1 4
1
(Tea +
1
(Poly
(1965 eft UFG
(l.elomyuearcomal
(Operator + |to become a
1 1 (Autoclave (Clergyman.
|1 1 (Cleaner
1 J (1955-65.
1
1
41
1
1 Yea
(High from 1
1
1
14944 to
1
1
1
1
1 1 ] Yea
4 1 4 1 1 1
41955.
1
| Medium from)
1 (
I 1955-1958 1 44
1 4
|Moderate
1 1 1 1 1 1
(1956-56 (labourer
|
(
11956-57
|
Iprod helper (
(1957-70
(
(operator (1970-75
( (
1 jelectrlclan |
I
J Dr M N Jotmeou
(letter of
(3 Nov 1982
(aitd
(28 Feb >983.
i
(Ur Dacey
(letter at
(5 Sept 1983.
4 1
1 IK U l.aundrle
|let ter of
112 Sept 1983
lapotted at (medical
1 May 1983.
|Testing
|commenced
1975-present o ratiir
(May 1983
l
J_________
I
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS U VISION
LIVER AnglOBarcoaa Caaea - (Uevlew Da a: 1 Jan 1964)
Rage 27
a
OOUNTRY AND REFERENCE NO
NAME OR INITIALS
DATE OF BIRTH
COMEANT
10 II 12 11 14
FACTOR*
FIRST VC EXPOSURE
UATE OF DIAGNOSIS
AGE AT DIAGNOSIS
TEAKS OF EXPOSURE TO
DIAGNOSIS
TEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
15
OTHER CAREER HIGHLIGHTS
OTHER COMMENTS
YUGOSLAVIA 01
05.04.14
Jugo Vlnll
Split
00.00.53 08.04.73
59
20
08.04.73
02
15.11.31 Jugo
Spilt
00.00.50 12.07.73
42
23
IB 12.07.73
Yea*
Vlnll
03
21.12.31 Jugo
Split
04.06.54 11.01.76
45
22
22 11.01.76
Yea*
Vlnll
04
11.06.30 Jugo
Split
15.12.58 03.09.78
Vlnll
20
IB 03.09.78
Yea
VCN Production
VCH Production
SAK1C et al paper Env Health Perspective Vol 17, pp 189-192 1976
Mn hie letter of 1 Oct 1978, Or Splrtaa of NIOSII changed ilia atatuu of Cane 02 to VCN production eaployee. Ur Splrtaa also notified a new Case 03 alao a VCM production worker
Koae Kaalnaki Letter of 19th June 1980 and IARC letter of 1 April 1982
gsmian
Incidence of ASL Cases Per Annum
By date of death
TABLE 1
(Review Date - 1 Jan 1984)
Page
1955 6 7 8 9
1960 1 2 3 4 5 6 7 8 9
1970 1 2 3 4 5 6 7 8 9
1980 1
2
3
Total
1 0 1 0 0 0 1 1 0 2 0 0 1 5 3 2 3 5 7 6 li 11 9 10 5 10 4
1
4
103
N.B.
1 Does not include Italian 01 but does include German 03. 2 The 1977 total includes US case 24 which Is a Cholanglosarcoroa. 3 The 1982 total does not include US 33 and 34 who are alive and F 15 who is alive. 4 The 1983 total does not include US 36 and F 16, who are alive
fsvsnan
Distribution of ASL Cases by Country
USA W Germany France Canada UK Sweden Yugoslavia Italy Czechoslovakia Japan Belgium Norway
33 *** 21 ** 17 *** 10
8 J **** 4 ***** 4* 2 2 1 1
TABLE 2
(Review Date - 1 Jan 1984)
Page 29
Total
108
* Omit ItOl - atypical case of PVC bag extruder. ** Includes GE03 aerosol can filler. *** includes case US 24 which was diagnosed as Cholangiosarcoma & US 33, 34 and 36; and F 15 and 16 who are alive **** includes one monomer worker. ***** includes two monomer workers.
i.e Western Europe North America Rest of World
57 43
8
Total 108
bsisiiyn
Pattern of ASL Cases by Factory
TABLE 3
(Review Date - 1 Jan 1984)
(a) W Europe
Of the 57 cases in W Europe, 46 have occurred in clusters at 10 factories. Of the 21 German cases, 18 have occurred In clusters at 4 factories.
ASL Cases
Kemanord, Sundsvall PCUK, Brignoud Dynainit, Troisdorf Chloe Chimle (Formerly RP), St Fons Wacker, Burghausen CWH, Marl ICI, Hillhouse BP, Barry Solvay, Tavaux Lonza, Waldshut
5 5 10 8 4 2 2 6 j2 2
46
Page 30
NB: There are 31 pre 1962 PVC plants in W Europe; 18 of these have had ASL cases (Ref Table 8)
(b) N America
Of the 43 cases in N America, 37 have occurred at four factories out of a total of 49 factories - in N America 39 plants have not had ASL cases.
ASL Cases
BFG, Shawinigan BFG, Louisville UCC, S Charleston Goodyear, Niagara
10 13 10
4
3~7
NB: There are 29 pre 1962 PVC plants in N America; 10 of these have had ASL cases (Ref Tables 9 & 10)
(c) Rest of World The 8 ASL cases are believed to be in 1 cluster of 4 and 2 clusters of 2 cases.
esisnan
TABLE 4A
(Review Date - 1 Jan 1984)
page 31
Latency Periods (Years from first Exposure to Diagnosis)
W Europe
No of Cases
Total Years
Average
Belgium
1 18 18
France Germany
17 438 25.76 * 21 385 18.3 *
Italy
4 74 18.5
Norway
1 22 22
Sweden
5 122 24.5
N America Rest of World
UK
US Canada
8 189 23.62
57
1248
21.89
33 835 25.30
10 204 20.4 *
43
1039
24.16
Summary
Czechoslovakia Japan Yugoslavia
2
2
4 8
30 15.0
39 19.5
85 21.2 154 19,2
W Europe N America
57 43
1248 1039
21.89 24.16
Rest of World
8 108
154 2441
19.2 22.60
os is i nan
* Of the countries with^lO cases, France and USA have average latency period above world average and Germany well below.
DISTRIBUTION OF LATENCY PERIODS
TABLE 4B
(Review Date - 1 Jan 1984)
Page 32
1
1 | 0-9 yrs
Belgium
1 1 1 1 i
Canada
1
I Czechoslovakia 1
France
1
Germany Italy
1 1
Japan Norway
1 i 1
Sweden
1
UK i i
USA
1
Yugoslavia TOTAL
i i 1 ii
i
i 1 1 i i li II
i I I i | li ii Average 10-14 yrs j 15-19 yrs | 20-24 yrs j 25-29 yrs | 30-34 yrs j 35+ yrs j| Total ii Latency
1 1 1 i 1 ii ii Period
1 1 I 1 i li li
i I t
3t
1 1i
l
1
1 l
5j
1 1
21
i It ii
I
l >i
18
11 i 1
i II 10 ii 20.4
1 I 1 i i 11 11
L{
1|
1
1 i II 2 li 15.0
1t
4I
2i
1 5i
1 2|
11 I i
3 li
17 i i 25,76
4!
9i
6* J
1 2I
i i1 i1 | II 21 i i 18.3
1 2i 2{ i1
1 Li 1| l1t
1 1 1|
1 l I i 11
1
1
II
4 i1
18.5
I ii
1 i II 2 ii 19.5
11 11
1 i II l 1 i 22
1 1 1 i 2I
2|
2I i
7|
1 I 1
7|
I 21
1 31
1 8i
1 1i
1 2i
I 4i
1i ii ii .5 ii 24.5
ii ii ii 8 ii 23.62 1 1 11 5 li 33 ii 25.30
1 1 11 11
1 1 4 I i 1 ii 4 ii 21.2
1 1 1 i 1 H ii
1 Ht
1 29 |
I 28 |
1 22 i
i 91
ii n 8 11 108 ii 22.60
i 1 1 i f ii li
* Includes G 03 aerosol can filler
IQlSi Ibfi
(Review date 1 January 1984)
Page 33
TABLE 4C
LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE
MAX POSSIBLE i
YEAR OF
LATENCY PERIOD
| ARITHMETIC MEAN
LATENCY PERIOD 1 FIRST EXPOSURE
1 OF LATENCY PERIODS
11
44 1 1939 43 1 1940 42 I 1
38* 37,21,37, kl **
1 1 244 - 34.86 |7
41 1 2
32,38
I
40 1 3 14
38,14,32
|
28,11,24,20,24,34 , 391
718 - 26.59
15
27,22,28,29
I 27
16
21,29,31,26,28,15,23,I
1
30,35***
1
36 1 7
29,24,29,28
1
35 1 8 19
28,24,34 30,26,20
| 1 458 = 24.11
l 1950
26,22,31,19,23,14,33 1
19
|1
19,28,17,28
1
31 1 2
21**,15
I
30 1 3
25,22,23,22,20
1
i4 1 15
21,21,25,25,21,28***,! 22 1 22,23,24,14,19,21,27 V
592 28
_ 21.14
1
27***
}
16
26 I
7
21,12,27*** 19,17,15,13.16
| 1
25 I 8
18,18,15.17,20
1
1 9 1 16,21
1 328 = 16.4
1 1960
13,18
1 20
II
15,16,16,16,19,18,12 1
21 ! 2
13,18,17,12
1
20 | 3 1 16,17
14
16,17
I 5 1 11
1 1 102 = 14.57
17
16
9
1
16 | 7
16
1
15 1 3
1
19
1
1 1970
l
|1 1
1
11 t 2
1
10 1 3
1
1 1 TOTAL 1
4
108
1 1 2442 a 22.61
I 108
* Cholangiosarcoma ** Aerosol can filler *** US33, 34 and 36; and F15 and 16 still alive.
i 1 1 1 1 1 1 1 1 1 1 i 1 1 1 1 1 1 1
VI CO
:
VIOLA
1
MALTONI 1 GOODRICH |
PJST80061400,11/WPX7-2
URL 1516
(Review date 1 January 1984)
Page 54
TABLE 4D
LATENCY PERIODS OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND GEOGRAPHICAL LOCATION
MAX POSSIBLE LATENCY PERIOD
YEAR OF
l
FIRST EXPOSURE 1
LATENCY PERIODS IN
WESTERN EUROPE 1
NORTH AMERICA
ROW
1l
44
1939
1
43
1940
1
1 38* 1
42
1 | 37,41***
1 21,37
41 2 1
1 32,38
40
3 1 38
1 14,32
1
4 1 28
1 11,24,20,24,34,39
5 1 27
1 22,28,29
6 I 21,29,31,33
1 26,28,15,23,30,35***
36
7 1 29
! 24,29,28
35
8 1 28,34
1 24
9 1950
1 30,26 1 26,22,31
1 20 1 19
23,14
1 1 19,28
1 17,28
31
2 1 21**
1 15
30
3 1 25,22
1 23
22,20
4 I 21,21,25,25 5 1 22,23,24,27*** 6 1 21,12
1 21,28*** ! 14,19,21,27*** 1 27***
22 1
26
7 1 19,17,15,13
1
25
8 1 18,18
i 15
16 17,20
9 1 16,21
1
1960
1 13,18
1
1 I 15,16,16,16,19,18 ! 12
1
21
2 I 13,18,17
1 12
1
20
3 1 16,17
1
4 1 16
1 17
1 1
5 1 11
1
1
6 19
1
1
16
7 1 16
1
1
15 8 1 91
1 1
1 1
VIOLA 1970
1
1
1
1 21
1
1
I | MALTONI 31
TOTAL
1 57
1 1 43
1! 81
* Cholangiosarcoma ** Aerosol can filler *** US33, 34 and 36; and F15 and 16 still alive
PJST80061400,12/WPX7-2
(Review date 1 January 1984)
TABLE 4E
Page 5i
PLANT
START UP DATE
LATENCY PERIODS OF ASL CASES
NO OF CASES
AVERAGE LATENCY PERIOD
LOUISVILLE SHAWINIGAN S CHARLESTON TROISDORF
|1 l1 1 1
1940? 1941? 1939? 1954
1
12,14,15,19,19,20,24,27,28,28,28,29,29 1
I1 11,12,14,21,22,23,24,24,26,28
1 1 1
I1 24,30,32,32,34,35,37,38,38,39
1 1 1
1 1
12,13,16,16,17,18,19,21,23,25
f 1 t
1
13 10 10 10
I 1 i 1 i 1 1 1 1
22.46 20.5 33.9 18
JD r~ V7
$
PJST80061400,13/WPX7-2
(Review date 1 January 1984)
TABLE 4F
Page 30
LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT
YEAR OF FIRST I
EXPOSURE
| S CHARLESTON
1939
I 38
1940 1
I 1 37
2 1 32,38
3 I 32 4 1 24,34,39
51 6 1 30,35 71
81
9 1950
1
1 1 1
21
31 41
^
51 61 71 81
91
1960
1
11 21
1
00
CN
O'C'J
LOUISVILLE
20 28,29,27 24 19 15 28 14,19
12
SHAWINIGAN 21 14 11 ,24 22 26,28 24
23
12
TROISDORF
21,25 23 12 13 16,16,19,18, 17
PJST80061400,14/WPX7-2
(Review date 1 January 1984)
TABLE 4G
Page 37
PLANT
SUNDSVALL BRIGNOUD ST FONS
START-UP DATE I LATENCY PERIOD OF ASL CASES NO OF AVERAGE PERIOD
CASES
l I 1945
1 I 16,19,27,29,31
11 \ 5 1 24.4 years
1 1 1950
1 1 11,16,18,26,30
1 5 i 20.2
1 | 1939
i 1 21,28,29,37,38,27,41,34-
1 8 i 31.88
BARRY
|
i BURGHAUSEN |
NIAGARA
1 1
1
SPLIT
1 |
1
1948 1933 1947
1941
1 9,17,18,28,31,33
\
I 17,21,22,25
1 1 15,17,21,23 1 1 1 20,20,22,23 1
1 6 | 22.66 1
1 4 | 21.25
1 4 1 19 11 11 1 4 1 21.25 11
U R L 15166
PJST80061400,15/WPX7-2
(Review date 1 January 1984)
Page
TABLE 4H
LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT
YEAR OF
FIRST EXPOSURE 1939 1940 1 2 3 4 5 6 7 8 9 1950 1 2 3 4 5 6 7 8 9 1960 1 2 3 4 5 6
| | 1 1
1 l 1 1 1 1 l 1 1 1 1 1 1 1 1 1 1 1
I 1 1 1 1 I
SUNDSVALL
27* 31 29
1
19
1 1 t 1 1 ! 16 1 1
BRIGNOUD
26,30
1 1 18 1 16 1
1 11
1 ST FONS BARRY
1
37 , 4i
38
29 28,34
31,33 28
1
27 21 1
1 1
11
11
18 17 1
1 1
91
1 BURGHAUSEN |
1 ! 1 1 1
1 1 1
1 1 1 I 1 1 25 1 21 1 22 1
1 17 1
1
1 1 I
1 1 1 1 1
NIAGARA
15,23
17
1 21
1 ! 1 1 1 i 1
SPLIT |
-|
23*
20 22*
I
t i 1
20 '
i3--D
s\
c--nj
* Monomer workers
JS/JH/DSO 16 25 January 1984 PJST80061400,16/WPX7-2
TABLE 5
(Review Date - 1 Jan 1984)
Page 39
Annual Incidence of ASL Cases (Date of Death) by Geographical Area
1955 7
1961 2 4 7 8 9
1970 1 2 3 4 5 6 7 8 9
1980 1 2
1983 TOTAL
1
11
1
j Western Europe i North America ] Rest of World | Annual Total
1
11
\
1
|1
i
i1
1
i1
t
11
1
|1
1
i1
\
i1
1
i1
1 i1 1 1i2
j1
I
1
I1
1
|5
i
i5
i1
t2
I
i3
i1
i1
1
I2
i1
|2
i
13
14
{1
i
i5
|1
i4
i 318
t3
>2
I
~1 5
1 6 1 4 1 1 f 11
i6
13
1
2 j 11
|6
i3
1
i9
|7
i2
i
1 1 10
|5
|
1 -[5
| 6 1 4 1 - J 10
j4
1o
1 ~i4
io
|1
} nil to date |
1
13
11
i nil to date |
3
|
55 ** |
40**
1
8 | 103
* Includes G03 aerosol can filler but omits It 01 bag extruder
** Does not include US33, 34 and 36; and F 15 and 16. All still alive.
{ Cumulative {
| Total
I Key Events
1 {11 i2 \ j 31
1 1 1 i
i4 1
1
161
1
17 1
I
t 12 1
1
i 15 1
1
1 17 i 20
1 25 i 33 1 38 f 49 | 60
1 I 1 1 1
\
1
i Viola 1 1 I Maltoni | Goodrich
1 1
i 69 I
1
1 79 1
I
1 84 I 94 | 98 1 99 (103
1 1 1 1 1
1 1 1 1 t
1
ay is nan
(Review date 1 January 1984)
TABLE 6
Page 40
ASL CASE NUMBERS BY YEAR OF DEATH AND GEOGRAPHICAL LOCATIONS (EXCLUDING IT01)
1 KEY 1 i EVENTS
1
\
1 1955 6
17 8 9
1960
1 2
1 Viola
1 1 1
IMaltoni 1 Goodrich
3 4 5 6 7 3 9 1970 1 2 3 4 5 6 7
1a
19 1980
I1 12
3 Total
f
1 WESTERN EUROPE
1 I NORTH AMERICA
1 1 REST OF WORLD
11
1 1 Cl
1 1
I 1 C2
1 1
11
11
i1
1 US8 j C3 t 1 US5
1 1 1 1 Cz2
11
FI
G1 Swl G2 Nl,Sw2,UKl,It2 G3**
1 1 l C4,C5,US4,US7,US10 1 US12.US16 ! US11 I C6,US2 1 C7 1 C8.US1.US3.US23
1
I 1 1 f 1 I 1 Yl.Y2,Czl
G4,G5.UK3 F2,F3,G6,G7,G8,It3
1 C9.US13 * 1 US6,US9,US18,US26
1 1 Japl
Bl,F4,F5,F6,F7,Sw3
1 US 19,US20,US22,
1 Jap2,Y3
F8,F9,G10,Gll,G12,Sw4 F10,Fll,G9,G13tG15
1 C10.US21,US24* 1 US27.US28
1 1 Y4
G16.G17
1
1
F12,F13,UK4,UK5,G18
1
1
UK6, UK7,G19,Sw5,G20,G21 1 US17, US29, US30, US32
It4,F14,UK8,G22
UK09, It5, F17 55 ***
1 1 US 31
1 US35 1 40***
f 1 1 18
11
* Cholangiosarcoma ** Aerosol can filler *** Does not include US33, 34 and 36; and F15 and 16.
All still alive.
m i si in n
PJST80061400,1/WPX7-2
URL 151 70
(Review dace 1 January 1984)
Page 41
TABLE 7
ASL CASE NUMBERS BY YEAR OF FIRST EXPOSURE AND GEOGRAPHICAL LOCATION ("excluding ITQ1)
KEY EVENTS
WESTERN EUROPE
NORTH AMERICA
REST OF WORLD
Viola Maltoni
1939 1
40 1
1 iFrl1,Frl6***
2l
3 1 Frl4
4 IUK1
5 | Sv2
6 |Frl,Fr3,Sw4
7 |Sw3
8 IFr9, Frl7
9 1Frl2,Fr4
1
50 |Fr7,Nl,UK8,UK9
1 |Swl,UK5
1
2 |G3**
3 |G15,It3
4 |G7,G8,UK4,G19
5 |G11,G16,G18, Frl5*** 1
6 1 FRIO ,G1 . 7 |Fr8,G4,It2,G2
i
8 IFr6,B1
9 |Fr2,It4
1
60 |G5,G13
1 |G9,G10,G12,G17,G20,G22|
2 |G6,UK6,G21 3 1Frl3, UK7
1
4 1 Sw5
5 I Fr5
1
6 IUK3
7 1 It5 8i
1
9
70 I
1
1| 1 2I i
31 1
1 Total!57
1 I
11
US24*
1
1
C3,US27
1
US13, US29
1
C2,US19
1
Cl,C5,US5,US7,US28,US35 1
C4,US3,US9
1
C7 ,C9,US8,US11,US21,US31 1
C6,US22,US26
1
US1 1
US 12
1
US16
IY2, Cz2
US10, US32
1
US4 1
CIO i Japl >Y1
US18,US33***
|Y3
US2,US17,US20,US34*** 1
US36***
1 ICzl
US23
1 Jap2 i Y4
1
1
C8 1
US6 1
1
US30
1
1
1
1
1
1 1 1 1 1 43 IS 1
* Cholangiosarcoraa ** Aerosol can filler *** US33, 34 and 36; and Fr 15 and 16 are still alive.
t
PJST80061400,2/WPX7-2
(Review date 1 January 1984)
Page 42
TABLE 8
WESTERN EUROPE FVC PRODUCERS - START-UP DAIES vs ASL GASES (OUTTING G03)
URL 15171
I START-UP | COUNTRY NAtE I COMPANY mE 1
IOCATICN
j ASL CASE NUMBER 1
YEAR OF
YEAR 1
1
1
1 1 1st Exposure
1931 (West Germany (BASF 1933 |West Germany JWacker
I Udwigshafen (Burghausen
1 104,07,11,15
1 (57,54,55,53
1938 1 Italy 1939 (France
IMontecatini (Acna 1 Rhone Pculenc 1 St Fons
\l [03,09,10,11,14, (46,48,56,41,43,
11
1
115,16,17
155,41,48
1940 (United Kingdom|ICI
(Runcorn
1
1
1940 I United Kingdom| ICI
(Hlllhouse
101,04
144,54
1945 1 Sweden
t Kemanord
I SundsvaUC Stockvik) (01,02,03,04,05 (51,45,47,46,64
(Switzerland (Lonza
ISins
1
1
1946 1 France
(Rhone-Etoulenc (Rousillon
101
(46
1947 [ Italy
I Montedison
(Porto Marghera
(02
157
1948 1 United KingdanlBP Chan
(Barry
(03,05.06,07,08,09(66,51.62.63,50,50
(West Germany IRils
IMarl
109,10
161,61
1949 (Belgium
1 Solvic
IJeneppe
101
158
1950 |France
|Puk
IBrigncud
(02,04.05,06,12 (59,49,65,58,49
(France
1 Fhone-Poulenc I St Auban
707------------------- 750-- --------------
(Bollard (Norway
I Shell (Norsk
literals |Heroya
1 (01
1 150
1951 1952 1953
(Italy (Italy (Austria (France
(Montedison (Montedison (Halvic (Solvic
(Brindisi ITemi 'lHallein (Tavaux
1 1 1 (08,13
t 1 1 (57,63
1 Italy
1Solvic
1 Ferrara
(03
153
1 Spain
(Rio Rodano
! Hemani
1
1
(United Kingdom]BIP
(Aydiffe
1
(West Germany | Hoechst
IGendorf
118
155
1954 (West Germany (Dynamit 11
(Troisdorf 1
101,02,08,12,16, (56,57,54,61,55,61 t t
117,19,20,21,22 (54,61,62,61
1
1955 1 Spain 1956 (Spain
(Monsanto Iberia (Monzon
ICaiqsa
1Sabinanigo
1 1
1 1
1
(Hispavic
(Torrelavega
1
1
1958 I West Germany ISolvay
1960 1 Italy
IS C Ravenna
IRheinberg (Ravenna
1 104
1 (59
1960 (West Germany (lonza
(Waldshut
(06,13
[62,60
1962 1 Portugal
(Cires
(Oporto
1
1
1965 (France
1Rhone-Poulenc (Montlucon
1
1
|Italy
IPozzi
IFerrandina
I
1
(West Germany 1 Wacker
(Cologne
1
1
1966 IWest Germany (Hoechst
I KnapsackC Frankfurt! 105*
160
1967 (France
(AID Chinde
IBalan
1
1
(Spain
IRio Rodano
(Miranda de Ebro 1
1
(Greece
(Esso Pappas (Diavata Salonika 1
1
1968 1 Belgian
IBadiphil
(Antwerp
1
I
1969 I United Kingdanl Vinatex
IStaveley
1
1
1 Italy
(Rumianca
I Cagliari Sardina 1
1
1970 1 Italy
(SIR
| ftorto Torres Sar 1
1
(United KingdomI ICI
IRuncom
1
1971 |Italy
IS C Ravenna (Ravenna
1
1
(Spain
I Hispavic
IMartorell
I
1
(Sweden
| Kemanord
ISterungsund
1
1
1 United KingdanlBP Chen
I Raglan Bay
1
1
1972 |Finland
IFekema
1Svartback
1
1
| HoHard
I DS-i
I Beek Limburg
1
1
1976 (France
t Soc Art D'vinyl1Mazlngarbe
1
1
1977 1 Spain
IMonsanto IberiaI Tarragona
1
1
* Laboratory worker in Research Department
**Pansac,Mira Venice, case not included. (It 05) due not knowing start up date of the Plant.
PJST80061400,3/WPX7-2
(Review date 1 January 1984)
Page 43
TABLE 9
USA PVC PRODUCERS - START-UP DATES vs ASL CASES
START-UP 1 COMPANY NAME
| LOCATION
I ASL CASE 1 YEAR OF
1
YEAR 1939?
1940?
1946? 1947
J |*UCC
1 I *BFG
1 1 I *UCC 1 Goodyear
1 I S Charleston
1 | Louisville
1 1 ! Texas City 1 Niagara Falls
I NUMBER
| 1st EXPOSURE
107,13,19,21,24 ,144,42,43,46,39,
t27,28,29,31.35 141,44,42,46,44
101,02,03,04,05 ,148,55,45,52,44, 106,09,16,17,22 ,162,45,50,55,47,
126,33,34
147,54,55
I [08,10,11,20
1 146,51,46,55
[ 1
1
1948 | Firestone
1 Pottstovn
I 12
149
1
1950
I Uniroyal
1 1 Monsanto
! Painesville | (closed 1975) I Springfield
1 1 [ 32
1 1 151
1 1
1952
1953 1954
1 Dow 1 BFG I Diamond 1 General Tire
1 Midland 1 Avon Lake I Deer Park 1 Ashtabula
1 1 18 1 ! 36
[ 154
1 1 56
1
1 1
1956 I Air Products
j Pensacola
1 Atlantic Refining 1 Brooklyn
1 1
! 1
1 1
I Borden
| Leominster
1
1
I Conoco
1 Hebronville
1
1 BFG
I Niagara
1
I Great American
1 Fitchburg
123
J I Plastics
1
1
| Hooker
1 Hicksville
1
1 Pantasote
1 Passaic
1
1 <" 1^ 158
1^
1^
1957 1 Atlantic Tubing | Tenneco
1 Cranston I Flemington NJ
1 1 30
1 159
1958 | Keysor Century
| Saugus, Cal
1
1
1960 1 BFG
1 Watson, Cal
1
1
| Air Products
| Calvert City
1
1
1
1 (closed March 1982)
1
1 Borden
1 Illiopolis
[
1
1962 1 Tenneco
1 Burlington NJ
1
1
1963 1 Conoco I Stauffer
1 Aberdeen, Miss 1 Long Beach, Cal
1 1
1 1
1965 1 Conoco
1 Assonet, Mass
1
1
| Ethyl 1966 I Diamond
| Baton Rouge I Delaware City
1
1
1 1
1 General Tire/Pantasl Mt Pleasant W Va 1
1
1 BFG
| Henry, 111
i
1
| Stauffer
1 Delaware City
1
1
1967 1 Allied
I Painesville, 0
1
l
1 1 Hooker
1 (sold to Robintech)
| Burlington NJ
1
1 1
1968 | Firestone
1 Perryville
t
1
1969 1971
1 BFG I Goodyear
} Pedrickton NJ I Plaquemine
1 Olin
| Assonet, Mass
1 (Formerly Conoco)!
| Conoco
1 Oklahoma City
1 1 1 1 1
1 1 1 j
1
PJST80061400,4/WPX7-2
TABLE 9 (Continued)
Page 44
USA PVC PRODUCERS - START-UP DATES vs ASL CASES
I START-UP| I YEAR | I 1972 |
1 1973 I
11 i1 11 11 11 1 1974 !
1i 1 1975 I
11 11 1 1979 |
COMPANY NAME
Nat Starch Borden Robintech
Atlantic Tubing Shintech Certain-teed Georgia Pacific Tenneco Firestone
| LOCATION
1 | Meredosia, 111 I Springfield | Painesville, 0 | (sold to Georgia 1 Pacific who | converted to I polystyrene) I Cranston RI \ Freeport, Tex 1 Lake Charles I Plaquemine, La 1 Pasadena, Tex | Plaquemine
i 1
ASL CASE NUMBER
1 YEAR OF
I
1 1st EXPOSURE |
f
1
1
I
1
1
1
1
1
1
1 1|
1
* My databank has no information on UCC before 1946 or BFG before 1950
NB Some of the plants in this list were closed down, some have changed ownership over the years
URL 15173
PJST80061400,5/WPX7-2
(Review date 1 January 1984)
Page JR
TABLE 10
CANADIAN PVC PRODUCERS - START-UP DATES vs ASL CASES
iSTART-UPl
COMPANY NAME
| LOCATION
1 ASL CASE 1 YEAR OF
1 YEAR I
1
1 NUMBER
1 1st EXPOSURE
1!
1 11
1 1943 I Goodrich
! Shawinigan
101,02,03,04,05 144 ,43,41,45,44,
1(1941?) |
1 106,07,08,09,10 147 ,46,61,46,53
11
1 11
11
1 11
1 1951 1 Monsanto*
1 La Salle
1
1
11
1 11
I1
1 1!
1 1957 | Goodrich
| Welland
1
1
11
1 11
11
1 11
1 1966 | Esso
11 11
1 Sarnia 1 1
1 1 1
1 1 1
j
! 1979 | Diamond Shamrock Alb l Fort Saskatchewan 1
1
11
1 11
* Terminated 1975
Xi
-ti.
PJST80061400,6/WPX7-2
(Review date 1 January 1984)
Page 46
TABLE U
EASTERN BLOC PVC FACTORIES - START-UP DATES vs ASL CASES
START-UP l COUNTRY NAME I COMPANY NAME
YEAR 1
}
Pre 1939 lEast Germany I State Company
1941 1 Russia
1 State Comps
1950 I Yugoslavia
IJugo Vinil
1951 t Czechoslovakia I State Comps 1955 [East Germany I State Comps
1956 S Rumania
|State Comps
1957 I Poland
1 State Comps
|Rumania
|State Comps
1 1958 1 Rumania
1 !State Comps
1959 |Hungary
I State Comps
1961 |Rumania
|State Comps
1963 1 Yugoslavia
!0his
1965 1 Bulgaria 1967 1 Poland
!State Comps !State Comps
1969 I Russia
iState Comps
1970 1 Rumania
I State Comps
1 Russia
I State Comps
1972 1 Yugoslavia
1Vinilplastika
1975 |Czechoslovakia!State Comps
1 Russia
I State Comps
1976 1 Yugoslavia
1 Hip
1977 1 Rumania
1 State Comps
| LOCATION
1 |Schopau (Vladimir et al 1 Split 1Novaky 1Bitterfeldt |Icechim lOsweicim (Dwory) 1Tirnaveni 1Turda |Risnov ]Berente Borsod (Borzesti 1Skopie I Varna 1Tarnow j Dieriinsk IRimnicu Vilcea iVolgograd
I Zadar !Neratovice IKalush Area }Pancevo IRimnicu Vilcea
1 ASL CASE | NUMBER
\ 1 101,02,03,04
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
oo'
,
"J
CM
O #>
o4.
YEAR OF
1
1st Exposure i
153 t50 157 t50
1
1 I 1
1 1 l
1 1 ! 1 1
PJST80061400,7/WPX7-2
(Review date 1 January 1984)
Page 4?
TABLE 12
JAPANESE PVC PRODUCERS - START-UP DATES vs ASL CASES
START-UP YEAR 1950
1951 1952 1951
1955 1956 1957 1960 1964 1966 1967 1968 1970
1971 1973 1974
COMPANY NAME
Chisso Corp Kanegafuchi Rag Tekkosha__________ Mitsui Toatsu Mitsubishi Mon Sumitomo Kag Denki Kagaku Nippon Zeon Toa Gosei________ Ryo-Nichi________ Nippon Zeon Nisshin Kagaku Kureha Kasei Shinetsu Kag Denki Kagaku
Kanegafuchi Kag
Chisso Corp______ Tokuyama Seksui San Arrow Kagak Sumitomo Kag Ryo-Nichi Shinetsu Kag Chisso Corp Denki Kagaku Kanegafuchi Kag Kawasaki Yuki Mitsui Toatsu Nissan Kagaku Shinetsu Kag Tekkosha__________ Asahi Glass______ Toyo Soda
1975 1977
Central Kagaku Toyo Soda Unknown
LOCATION
Minamata Osaka Sakata______ Nagoya______ Yokkaichi Kikumoto Shibukawa Kambara Tckushima Uozu_________ Takoaka Takeo________ Nishiki Naoetsu Ohroi
Takasago
Chiba________ Tokuyama Tokuyama Chiba________ Mizushima Tokuyama Mizushima Goi (Chiba) Kashima Kawasaki Sakai Chiba Kashima_____ Yokkaichi Hayatsuki Sakata Yokkaishl Kawasaki Yokkaichi Kashima
ASL CASE NUMBER
YEAR OF Is t EXPOSURE
01 . 02
53, 58
URL 15176
PJ ST80061400,8/WPX7-2
(Review date 1 January 1984)
Page 43
TABLE 13 SOUTH AND CENTRAL AMERICAN PVC PRODUCERS
START-UP I YEAR 1953 1954 1955 1956 1960
1961 1965
1966 1967 1968 1970
1971 1975 1976 1977 1978
1979
COMPANY NAME
Monsanto Mexica Policyd Geon Do Brazil Elchlor Electrochlor Viplastic Indupa SOC Paramanga PET Columbiana Carburo De Col Plasticos Omega Primex Policasa Petro Dow Poliraeros Mex Rico Chemicals Petroplas Indust Resistoc Huls Brasil Polychem Policyd PET Camacari
1 LOCATION
1
1i
| Lecheria (Mexico)
1
| Mexico City (Mexico)
1
1 Sao Paulo (Brazil)
1
| Sao Caetano (Brazil)
1
ICapitan Bermudez(Argentina)I
I Mendoz (Argentina)
I
| Cinco Saltos (Argentina) 1
I Paramonga (Peru)
1
1 Cartagena (Colombia)
!
1 Medellin (Colombia)
1
I Mexico
1
I Puebla (Mexico)
1
| Managua (Nicaragua)
1
| Conception (Chile)
1
1 St Martin Puebla (Mexico) 1
1 Guyanilla (Puerto Rico) 1
1 EL Tahlazo (Venezuela)
1
1 Tlazcala (Mexico)
1
I Cubato (Brazil)
1
1 El Salvador
1
I Coatzacoalcos (Mexico)
1
1 Camacari Bahia (Brazil)
1
ASL CASE NUMBER
1 YEAR OF
|
1 1st EXPOSURE 1
1
1
I 1
1
1
1
1
1
1
t
1
1
1 1
1
t 1
i
1
1 rn 1 r~
cn
--a -wj
'61400,9/WPX7-2
HI >15
IMPERIAL CHEMICAL INDUSTRIES PLASTICS DIVISION
LIVER Angloearcona Caaes - (Review Da e: I Jan 1984)
Prance Sheet t.
Page 8
1 1i
l 12
i1 1
I COUNTRY AMD 1 | REFERENCE J
NAME OK INITIALS
| NO
1
11
1 1 | Prance
1 l
[! IS IPKP
i 1
k
i
;i k it 1
k
1 16 |GIM
i1 i1
k
ik
ik
3 DATE OP
BIRTH
03.01.37
13.07.22
1l i\ -i 1
17 22.02.23
4 COMPANY
l 15
J____ 1 k | FACTORY
1 1 l 1
Chloe
ISc Pons
Chlale
>
(formerly i
RP) i
i
i
i
Chloe
i |SC Puna
Chlale
J
(Foraerly k
ftP) 1
1
1
k J 1
Chloe Chieie (Fornerly
RF)
6J
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
07.07.55 28.09.82
27.10.4J 05.01.83
I7.0&.4R 03.04.83
8 AGE AT DIAGNOSIS
45
61
60
9 YEARS OF EXPOSURE TO 0IAUN0S1S
27
41
34
10 U
YEARS OF EXPOSURE
DATE OF DEATH
27 Alive
38 Alive
28 03.04.83
12
HISTOLOCICAL CONFIRMATION
t1 13 1 14 |
11
1i
ESTIMATED 1
i
EXPOSURE | OCCUPATION |
LEVEL i
k
11 11
11
15
OTHER CAREER HIGHLIGHTS
1 t k
J ( 1 \ l k
16
OTHER COMMENTS
Yea tea
HIgh-20 yr Moderate 7 yr*
|Autoclave (cleaner (1955-1962 |autoclave (operator 11962-1982
| l ( | | i
11
11
High-33 yra|Polyerleat-|
Moderate- (ion Proceaa |
Low - 5 yralHan
1
1k
I Maintenance (
(Worker
|
C Concatitiot I Letter of 15 10 1983
I 1 1 1 1 |Retired (Jan 1979. |J C Cuutaasot (Letter of 15 10 1983
1
(Health 1
|
| Safety Agent|
JL
1 I k
High 23 yre
Autoclave Cleaner 1948-1971
Ollier uectoru of Sc Pone Factory 19711978
Retired 01.01.79 J C Contuaaot letter of 5 10 1983
easnari