Document 6bmM0G8Rg5YgYrnkGyx4oBBXm

FILE NAME: Oil Industry and American Petroleum Institute (API) DATE: 1951 Nov 3 DOC#: API016 DOCUMENT DESCRIPTION: Meeting Minutes & Attendee List - API Medical Advisory Committee f For Information Only - Not For Publication AMERICAN PETROLEUM INSTITUTE MEDICAL ADVISORY COMMITTEE FOURTEENTH MEETING Minutes of Meeting November 3> 1951 The Conrad Hilton Chicago, Illinois MEMBERS PRESENT OR REPRESENTED B. B. Reeve - Chairman E. K. Linder - Vice Chairman Marshall Clinton - Secretary V. 0. Armstrong V. C. Baird (Rep. by Vincent T. Former) F. F. Boys J. Vm. Crookshank L. E. Curtis Kieffer Davie Robert E. Eckardt D. M. English Kenneth R. Fourcher T. M. Frank T. J. Kelly James V. Long E. P. Luongo M. N. Nevqulst James W. Osborn John C. Ruddock George M. Saunders Leo J. Vade E. Richmond Ware ASSOCIATES PRESENT L. C. R. D. J. S. R. C. T. E. Allan L. M. Beard, Jr. Bent Boylan Cole Devllliers E. Dooley Benderson E. D. Wilde R. M. Landon K. G. Mackenzie R. C. Mithoff C. A. Nellson ~ ` F. J. Sanders R. M. Shepardaon F. M. Watkins GUESTS Clyde M. Berry R. C. Carrell Philip Drinker W. N. Fenney N. V. Eendrlcks A. V. Eorton Robert A. Behoe John J. Phalr B. N. Shoemaker Robert E. Stevart D. v. Stroop . sso Standard Oil Co. - Lago Oil & Transport Co. - Harvard University - The Texas Co. . standard Oil Development Co. - University of Cincinnati - University of Cincinnati - university of Cincinnati - Standard Oil Co. (Indiana) American Petroleum Institute - American Petroleum Institute Total in Attendance - U8 A PI 07093 MEMBERS ABSENT Theodore E. Allen C. H. Hlne Warren F. Kahle ASSOCIATES ABSENT E. W. Adams W. R. Argyle C. L. Brown C. R. Brown L. 0. Crockett J. B. DeLaune R. S. Driver R. C . Page R. B. Roaper W. R. Leris Robert Bell Lynn Clark R. Miller R. W. Faulk Nelson J. Gothard James E. Hill E. W. Isom D. W. Larmer C R McKay W. H. Price I INTRODUCTION OF MEMBERS AMD GUESTS The chairman welcomed and Introduced members and guests who had not attended previous meetings of the committee. ACTION n MINIH'KS QF TSnVTttK'fflR MEETING The committee voted to approve the minutes of the Thirteenth Meeting as circularized. ~ ' HI REPORT OF SUBCOMMITTEE ON ATMOSPHERIC POLLUTANTS - DR. E. P. IPONOO. CHAIRMAN Doctor Luongo reported that his subcommittee had deferred consideration of its assignment because of a suggestion made by W. L. Stewart, Jr., API Vice President for Refining, that the Institute should appoint a national comnlttee to find answers to all petroleum air-pollution problems. In the understanding that the General Committee, Division of Refining, planned to discuss Mr. Stewart's proposal on November 6 , the only action taken by the Subconaittee on Atmospheric Pollutants was to record, for transmittal to the General Committee, Division of Refining, a consensus that the extent of health hazards which might result from petroleum pollutants in the atmosphere is indeterminate from data now available. ACTION The report was accepted and amended to provide that the Medical Advisory Cosmittee tenders its services to the General Committee, Division of Refining, in any possible manner upon request. A P I 07094 y - 3- Note by secretary: By request^ three votes are recorded, against acceptance of the report on the basis that it failed to take cognizance of the charge given by the Medical Advisory Committee at Its Thirteenth Meeting. Appended Is a copy of Doctor Reeves letter to V. L. Stewart) Jr., under date of November 5, 1951. IV STATEMENT OF COMMITTEE OBJECTIVES. FUNCTIONS AND PROCEDURES As a newly-appointed member of the Medical Advisory Committee Doctor Kenneth R. Fourcher expressed his need for a statement outlining the committee's objectives) functions and procedures. ACTION The committee requested that D. V. Stroop, with the advice and counsel of past chairmen, prepare the' desired statement and circularize copies to all members well in advance of the Fifteenth Meeting. V REPORT OF SUBCOMMITTEE ON CARCINOGENICITY - DR. M. N. NEWQUIST. CHAIRMAN On behalf of the subconalttee, Doctor Newqulst submitted eleven recommendations for adoption as follows: 1. That the progress report from Kettering Laboratory, dated September 25, 1951, bo received aftd filed. 2. That a Research Project Advisory Comnlttee be appointed by the chairman of the subconalttee to counsel, to review the various phases of the research work, and to obtain all samples to bo tosted. 3. That no now samples be incorporated Into the program except: a. One sample of coal tar; b. One sample of vacuum distillate, 650-800F, from each of the following pipe line samples of crude oil: California, Mid-Continent, Gulf Coastal, Middle East; and c. Such samples as are required to explore further analytical techniques after the anomalies on the present samples are resolved. U. That the subject of co-carcinogens bo clarified Insofar as is feasible. API 07095 -k- 5 . That synthesis of any carcinogens and solvents which may he required he aade hy arrangements with API Project k 2 . 6 . That a limited number of animal tests of high-potency oils he made hy stopping the application of the oils when papillomas first appear on each mouse. 7. That it he ascertained whether or not groups of twenty mice are statistically adequate for biological testing in this project. 8 . That potency figures be expressed separately for papillomas and malignancies. 9. That detailed data sheets on all completed experiments he included as a part of all progress reports from Kettering Laboratory. 10. That the Interim report, dated September 2 5 , 1951 > he not transmitted to the Institute of Petroleum, London, until after collaboration of the Besearch Project Advisory Committee with Doctor Xehoe, in order to allow for inclusion in the text more recent findings and conclusions in connection with current studies. 11. That the epidemiological survey work he continued on its present basis for the time being. Following an extended and detailed discussion of the report, the committee voted to amend the report hy striking out recoianendationa numbered 3 to 10 inclusive, to accept the amended report, and to direct the Research Project Advisory Conzn.lttee to meet with project directors within 30 days to work out the 1952-53 program. . VI REPORT OF SUBCOMMITTEE OB FIRST AID - DR. T. M. FRANK. CHAIRMAN Doctor Frank reported that the suhconznittee had reviewed the first edition of the API First-Aid and Safety-Training Guide and had noted several suggestions for Improvement and correction for inclusion if, as, and when the second edition is printed. Particular attention was given to the methods of artificial respiration illustrated and described in the guide and to the suhconznittee 'a recosmendations of April 1951 -Tor the distribution of artificial respiration illustrations published in the Ivy report. The subcommittee voted to rescind its previous action and to recommend no change in the artificial respiration section of the guide at this time. Each member of the Medical Advisory Committee is requested to make a critical review of the first-aid guide and to transmit hie A PI 07096 - 5- criticisms and suggested changes to the subcommittee chairman, with carbon copy to D. V. Stroop. ACTION The report vas adopted by the Medical Advisory Committee. vn REPORT OF SUBCOMMITTEE ON TOXICOLOGICAL REVIEWS - DR. MARSHALL CLINTON. CHRMN Doctor Clinton referred to action taken at the Thirteenth Meeting when the subcommittee vas authorized to formulate plans for five-year periodic revision of each toxicological review. He reported results of his work on this matter by Introducing Professor Drinker, vho stated the Impracticability of estimating the cost of revising the reviews. It vas his proposal that a fund of $6,000 should be established as a maximum amount which could be expended during the first year In which the revisions are to be made, but that charges against the fund should be restricted to actual cost plus 20 per cent for overhead as required by Harvard University. ACTION The committee recommended the acceptance of Professor Drinker's proposal with the understanding that, prior to revision, each toxicological review would be studied to ascertain the need for and desirability of revision. vni REPORT OF CONSULTANT - PROFESSOR PHILIP DRINKER The committee received an informative and timely report on several subjects of interest. H . REPORT OF SUBCOMMITTEE OH FLUORIDES - DR. GEORGE M. SAUNDERS. CHAIRMAN Doctor Saunders read the minutes of the subeonmittee meeting held November 2, 1951, as follows: "The chairman read a sumnary of an extensive report distributed to members earlier. Reference vas made to E. J. Largent's letter of October 9 1951, requesting consents on attached manuscript of a proposed paper which will be circulated to subcamnlrcee members for their comments. "Doctor Kehoe told the subconnlttee that the work now permits setting limits deflnii^ safe concentrations for long-time exposure. He said the number of contributors remains the same; the budget of the order of $20,000/yoar; and that interest and practical Importance of this work Is expected to Increase. A meeting of sponsor representatives is planned for about the first of the year, and those concerned will be advised relative to the date. A PI 07097 i "A notion vas passed to contnue participation In the fluoride work at Kettering for another year, In the amount of $2 ,500." ACTION The Medical Advisory Coanlttee adopted the subcommittee recommendation for the contribution of $2,500 to the University of Cincinnati as the oil Industry share of expense for work during the year ending June 30, 1953. X REPORT OF SUBCOMMITTEE ON ECONOMIC POISONS - DR. T. J. KELLY. CHAIRMAN Doctor Kelly said there had been no need to hold a meeting, but he recommended the reappointment of the subcommittee for 1952. ACTION The committee accepted the chairman's recommendation. XI REPORT OF SUBCOMMITTEE ON CUTTING FLUIDS DR. F. T . B0I5, CHAIRMAN Doctor Boys stated he had no report to make but requested that the subcommittee be continued In 1952. ACTION The committee agreed to continue the subcommittee. XII REPORT OF SUBCOMMITTEE ON EXE HAZARDS - DR. KIEFFER DAVIS, CHAIRMAN Doctor Davis reported an apparent lack of necessity for activity by the subcommittee during 1951, but recommended the continuation of the subcommittee on a status quo basis, to be reactivated if and vhen the need arises. ACTION The committee accepted the report. xin REPORT OF SUBCOMMITTEE ON MEDICAL POLICIES k PRACTICES - DR. L. E. CURTIS.CHRMN Doctor Curtis stated the subcommittee had considered a proposal far a questionnaire survey of members to determine vhat each company Is doing In the field of Industrial medicine, but that no action had been taken. ACTION The progress report vas accepted. A PI 07098 y - 7- XIV REPORT OF SUBCOMMITTEE ON PHYSIOLOGY OF THE SKIM - DR. ROBERT E, ECKARDT,.CHRMN On behalf of the subcommittee, Doctor Eckardt reported two recommendations for adoption and submittal to the Safety Committee of the Board, as follove: 1. That $2,500 of Medical Research Funds nov on deposit should bo contributed to the University of Cincinnati for the support of Kettering Laboratory's research on basic physiology of human skin for the six-month period ending June 30, 1952. 2. That $5,000 should be included in the 1952-53 budget for the continued support of this project for the year ending June 30, 1953. ACTION The committee voted to adopt and to submit both recommendations to the Safety Committee of the Board. XV AROMATIC HYDROCARBONS The committee reviewed this subject as outlined in Doctor Eckardt's letter of August 10, 1951 (which was circularized to members and associates on August 23) and other communications from members and t associatee. ACTION Without objection, the chairman ruled that the subject should be tabled for further consideration at the next meeting. XVI HEW BUSINESS (No item of new business was presented.) ACTION 1I -- XVII TIME AND PLACE OF FIFTEENTH MEETING The committee voted unanimously to hold its Fifteenth Meeting in Cincinnati. Ohio, on Friday and Saturday, April 18 and 19, 1952. XVIII CONCLUSION OF GENERAL SESSION Upon the completion of general business, the general session was ------------------------------------- A P I 07099 -8- EXECUTIVE SESSION BUDGETS FOR 1951-1952 AM? 1952-1953 The committee reviewed the status of the Medical Research Fund, the present and proposed obligations for expenditures, and the preliminary staff estimate on amount to be solicited In 1952, as follows: Balance on deposit at API (10-1-51) prospective expenditures prior to June 1. Carcinogenicity 2. Retainer for Professor Drinker 3. Physiology of the Skin 30, 1952: $ 31,692.1*2 2,500.00 2,500.00 Apparent balance June 30, 1952 proposed solicitation of contributions 1952 Total available for fiscal year 1952-1953 $ 83,U31.81* 36.692.U2 6,739.1*2 1 0 0 ,000.00 11*6,739-1*2 Estimated maximum budget for 1952-1953: 1. Carcinogenicity $ 2. Fluorides 3. Physiology of the Skin 1*. Retainer for Professor Drinker 5. Toxicological Reviews 100,000.00 2 ,500.00 5 ,000.00 2 ,500.00 6 ,000.00 Apparent balance June 30, 1953 116,000.00 $ 30,739.1*2 ACTION The comnlttee voted to reconnend the estimated maximum budget and the proposed solicitation of $100,000 in special contributions from interested oil companies for the support of the projects for the year ending June 30, 1953* ********** IN APPRECIATION In appreciation for his conscientious and efficient service as chairman during 1951, the committee tendered a vote of thanks to Doctor B. B. Reeve. The Fourteenth Meeting was adjourned. Approved: B. B. Reeve, M.D. Chairman 12-U-51 Marshall Clinton, M.D. Secretary API 07100 COPY November 5, 1951 Mr. W. L. Stewart, Jr. Chairman, General Committee Division of Refining American Petroleum Institute 50 West 50th Street Row York 20, New York Dear Sir: Being informed of your suggestion for tho formation of an Institute committee to study air-pollution problems, I believe you may i bo interested in reviewing briefly the extent to which these problems i have been considered by the Institute's Medical Advisory Committee. Several years ago, soon after the Donora Incident, the Medical l Advisory Committee discussed possible toxlcities of petroleum industry pollutants in atmosphere and concluded that the potontlal problems of the Industry in atmospheric pollution might develop in the field of public nuisance rather than in the field of public health; therefore, the comnlttee dropped the subject from Its agenda except to establish contact with the work of the Committee on Disposal of Refinery Wastes through the agency of a member who served on both comnlttees. In April 1951 the Medical Advisory Committee voted to appoint a Subcommittee on Atmospheric Pollutants to study ways and scans of gathering information on the physiological effects of atmospheric pollutants and to report its recommendations to the next meeting. . When informed of your suggestion for tho formation of an Institute committee to study air-pollution problems the subcommittee i!t deferred action on its assignment and simply reported as a matter of i i record that the extent of health hazards which slight result from I potroleum industry pollutants in the atmosphere is indeterminate from 'E data now available. i The Medical Advisory Cosmittee tenders its services to the Goneral Committee, Division of Refining, on medical phases of any problems arising in the work of the division. i Very truly yours, /s/ B. B. Reeve M.D. , * Chairman, API Medical Advisory Conslttee 11 A PI 07101