Document 6bk8qy2GkeRvxgdMz7eo0xnEm

AH&&.6- $6(K A preliminary list of published references being considered in the update to the science Prepared following the completion of the environmental and human health risk assessments of the 4 notified polymers. February 3, 2006 New Substances Division Environment Canada New Chemical Substances Health Canada 000104 P-2 Table of Contents Environmental References......................................................................3 Peer reviewed journal articles........................................................................................... 3 Perfluorinated Surfactants - General...........................................................................3 Analytical Methods..........................................................................................................3 Physical Properties......................................................................................................... 4 Abiotic Degradation.........................................................................................................5 Biological Transformation...............................................................................................6 Atmospheric Chemistry of Precursors..........................................................................6 Environmental Monitoring...............................................................................................7 Biological Monitoring...................................................................................................... 8 Eco-Toxicology................................................................................................................ 9 Human Health References.....................................................................10 Peer Reviewed Journal Articles......................................................................................10 Human Exposure & Monitoring....................................................................................10 Hazard & Toxicology.................................................................................................... 12 Risk Assessment........................................................................................................... 13 Conference Presentations................................................................................................ 15 SETAC North America 2004 - Portland, O R .............................................................15 SETAC North America 2005 - Baltimore, M D ...........................................................17 SETAC Europe 2005 - Lille, France........................................................................... 17 Dioxin 2004 - Berlin, Germ any....................................................................................19 Dioxin 2005 - Toronto, Canada.................................................................................. 21 Fluoros: International Symposium on Fluorinated Alkyl Organics in the Environment - August 18-21,2005. Toronto, Canada...........................................24 000105 p.3 Environmental References Peer reviewed journal articles Perfluorinated Surfactants - General 1. Lehmler, H.J. Synthesis of environmentally relevant fluorinated surfactants - a review. Chemosphere 2005, 58, 1471-1496. 2. Prevedouros, K.; Cousins, I.T.; Buck, R.C.; Korzeniowski, S.H. Sources, fate and transport of perfluorocarboxylates. Environ. Sci. Techno!. 2006, 40, 32-44. 3. Renner, R. Piecing together the perfluorinated puzzle. Anal. Chem. 2005, 77, 15-16A. 4. Renner, R. The long and the short of perfluorinated replacements. Environ. Sci. Technol. 2006, 40, 12-13. 5. Renner, R. Arctic chemistry may explain perfluorinated mystery. Environ. Sci. Technol. 2004, 38, 215-216A. Analytical Methods 6. Alzaga, R. and Bayona, J.M. Determination of perfluorocarboxylic acids in aqueous matrices by ion-pair solid-phase microextraction-in-port derivatization-gas chromatography-negative ion chemical ionization mass spectrometry. J. Chromatogr. A 2004, 1042, 155-162. 7. Alzaga, R.; Petinal-Salgado, C.; Jover, E. and Bayona, J.M. Development of a procedure for the determination of perfluorocarboxylic acids in sediments by pressurized fluid extraction, headspace solid-phase microextraction followed by gas chromatographic-mass spectrometric determination. J. Chromatrogr. A 2005 1083: 1-6. 8. Flaherty, J.M.; Connolly, P.D.; Decker, E.R.; Kennedy, S.M.; Ellefson, M.E.; Reagen, W.K. and Szostek, B. Quantitative determination of perfluorooctanoic acid in serum and plasma by liquid chromatography tandem mass spectrometry. J. Chromatogr. B 2005 819: 329-338. 9. Holm, A.; Wilson, S.R.; Molander, P.; Lundanes, E.; Grelbrokk, T. Determination of perfluorooctane sulfonate and perfluorooctanoic acid in human plasma by large volume injection capillary column switching liquid chromatography coupled to electrospray ionization mass spectrometry. J. Sep. Sci. 2004, 24, 1071-1079. 10. Hori, H.; Hayakawa, E.; Yamashita, N.; Taniyasu, S.; Nakata, F. and Kobayashi, Y. High performance liquid chromatography with conductimetric detection of perfluorocarboxylic acids and perfluorosulfonates. Chemosphere 2004, 57, 273-282. 000106 P-4 11. Kaiser, M.A.; Larsen, B.S.; Dawson, B.J.; Kurtz, K.; Lieckfield Jr, R.; Miller, J.R.; Flaherty, J. Method for the determination of perfluorooctanoic acid in air samples using liquid chromatography with mass spectrometry. J. Occupat. & Environ. Hygiene 2005, 2, 307-313. 12. Karrman, A.; van Bavel, B.; Jarnberg, U.; Hardell, L. and Lindstrom, G. Development of a solid-phase extraction-HPLC/single quadrupole MS method for quantification of perfluorochemicals in whole blood. 2005 Anal. Chem. 77: 864-870. 13. Larsen, B.S.; Kaiser, M.A.; Botelho, M.; Wooler, G.R. and Buxton, L.W. Comparison of pressurized solvent and reflux extraction methods for the determination of perfluorooctanoic acid in polytetrafluoroethylene polymers using LC-MS-MS. 2005 Analyst 130: 59-62. 14. Martin, J.; Kannan, K.; Berger, U.; de Voogt, P . ; Field, J . ; Franklin, J . ; Giesy, J .P .; Harner, T . ; Muir, D.C.G.; Scott, B.; Kaiser, M.; Jarnberg, U.; Jones, K.C.; Mabury, S.A.; Schroeder, H.; Simcik, M.; Sottani, C.; Van Bavel, B.; Karrman, A.; Lindstrom, G.; Van Leeuwen, S. Analytical challenges hamper perfluoroalkyl research. Environ. Sci. Technol. 2004, 38, 250A-255A. 15. Powley, C.R.; George, S.W.; Ryan, T.W.; Buck, R.C. Matrix effect-free analytical methods for determination of perfluorinated carboxylic acids in environmental matrixes. Anal. Chem. 2005, 77, 6353-6358. 16. Richardson, S.D. Environmental mass spectrometry: Emerging contaminants and current issues. Anal. Chem. 2004, 76, 3337-3364. (Review) 17. Richardson, S.D. and Ternes, T.A. Water analysis: Emerging contaminants and current issues. Anal. Chem. 2005, 77, 3807-3838. (Review). 18. Risha, K.; Flaherty, J.; Wille, R.; Buck, W.; Morandi, R. and Isemura, T. Method for trace level analysis of C8, C9, C10, C 11 and C13 perfluorocarbon carboxylic acids in water. Anal. Chem. 2005, 77, 1503-1508. 19. Szostek, B.; Prickett, K.B. Determination of 8:2 fluorotelomer alcohol in animal plasma and tissues by gas chromatography-mass spectrometry. J Chrom. B 2004, 813, 313-321. 20. Taniyasu, S.; Kanna, K.; So, M.K.; Gulkowska, A.; Sinclair, E.; Okazawa, T.; Yamashita, N. Analysis of fluorotelomer alcohols, fluorotelomer acids, and short- and long-chain perfluorinated acids in water and biota. J. Chrom A 2005, 1093, 89-97. 21. Wojcik, L.; Szostek, B.; Maruszak, W.; Trokanowick, M. Separation of perfluorocarboxylic acids using capillary electrophoresis with UV detection. Electrophoresis 2005, 26, 1080-1088. Physical Properties 22. Buchanan, G.W.; Munteanu, E.; Dawson, B.A. and Hodgson, D. Concerning the origin of 19F19F NMR COSY and NOESY connections in the spectra of perfluorooctanoic acid, RF-palmitic acid-F13 and diethyl perfluorosuberate. Magn. Reson. Chem. 2005, 43, 528-534. 23. Ellis, D.A.; Denkenberger, K.A.; Burrow, T.E. and Mabury, S.A. The use of 19F NMR to interpret the structural properties of perfluorocarboxylate acids: A possible correlation with their environmental disposition. J. Phys. Chem. A 2004, 108, 10099-10106. 000107 P-5 24. Kaiser, M.A.; Cobranchi, D.P.; Chai Kao, C.-P.; Krusic, P.J.; Marchione, A.A. and Buck, R.C. Physicochemical properties of 8-2 fluorinated telomer B alcohol. J. Chem. Eng. Data 2004, 49, 912-916. 25. Kaiser, M.A.; Larsen, B.S.; Kao, C.-P.C.; Buck, R.C. Vapour pressures of perfluorooctanoic, nonanoic, -decanoic, -undecanoic, and -dodecanoic acids. J. Chem. Eng. Data 2005, 50, 1841-1843. 26. Krusic, P.J., Roe, D.C. Gas-phase NMR technique for studying the thermolysis of materials: thermal decomposition of ammonium perfluorooctanoate. Anal. Chem. 2004, 76, 3800-3803. 27. Krusic, P.J.; Marchione, A.A.; Davidson, F.; Kaiser, M.A.; Kao, C.C.; Richardson, R.E.; Botelho, M.; Waterland, R.L. and Buck, R.C. Vapor pressure and intramolecular hydrogen bonding in fluorotelomer alcohols. J. Phys. Chem. A 2005, 109, 6232-6241. 28. Lei, Y.D.; Wania, F.; Mathers, D. and Mabury, S.A. Determination of vapor pressures, octanolair and water-air partition coefficients for polyfluorinated sulfonamide, sulfonamidoethanols and telomer alcohols. J. Chem. Eng. Data 2004, 49, 1013-1022. 29. Liu, L. and Lee, L.S. Solubility and sorption by soils of 8:2 fluorotelomer alcohol in water and cosolvent systems. Environ. Sci. Technol. 2005, 39, 7535-7540. Abiotic Degradation 30. Gauthier, S.A.; Mabury, S.A. Aqueous photolysis of 8:2 fluorotelomer alcohol. Environ. Toxicol. Chem. 2005, 24, 1837-1846. 31. Hori, H.; Hayakawa, E.; Einaga, H.; Kutsuna, S.; Koike, K.; Ibusuki, T.; Kiatagawa, H.; Arakawa, R. Decomposition of environmentally persistent perfluorooctanoic acid in water by photochemical approaches. Environ. Sci. Technol. 2004, 38, 6118-6124. 32. Hori, H.; Yamamoto, A.; Hayakawa, E.; Taniyasu, S.; Yamashita, N.; Kutsuna, S.; Kiatagawa, H. and Arakawa, R. Efficient decomposition of environmentally persistent perfluorocarboyxlic acids by use of persulfate as a photochemical oxidant. Environ. Sci. Technol. 2005, 39, 2383 2388. 33. Hori, H.; Yamamoto, A. and Katsuna, S. Efficient photochemical decomposition of long-chain perfluorocarboxylic acids by means of an aqueous/liquid C 0 2 biphasic system. Environ. Sci. Technol. 2005, 39, 7692-7697. 34. Moriwaki, H.; Takagi, Y.; Tanaka, M.; Tsuruho, K.; Okitsu, K. and Maeda, Y. Sonochemical decomposition of periluorooctane sulfonate and perfluorooctanoic acid. Environ. Sci. Technol. 2005, 39, 3388-3392. 35. Yamada, T.; Taylor, P.H.; Buck, R.C.; Kaiser, M.A.; Giraud, R.J. Thermal degradation of fluorotelomer treated articles and related materials. Chemosphere 2005, 61, 974-984. 000108 P-6 Biological Transformation 36. Dinglasan, Ye, Y.; Edwards, E.A.; Mabury, S.A. Fluorotelomer alcohol biodegradation yields poly- and perfluorinated acids. Environ. Sci. Techno!. 2004, 38, 2857-2864. 37. Wang, N.; Szostek, B.; Folsom, P.W.; Sulecki, L.M.; Capka, V.; Buck, R.C.; Berti, W.R.; Gannon, J.T. Aerobic Biotransformation of 14C-labeled 8-2 telomer B alcohol by activated sludge from a domestic sewage treatment plant. Environ. Sci. Technol. 2005, 39, 531-538. 38. Wang, N.; Szostek, B.; Buck, R.C.; Folsom, P.W.; Sulecki, L.M.; Capka, V.; Berti, W.R.; Gannon, J.T. Fluorotelomer alcohol biodegradation - direct evidence that perfluorinated carbon chains breakdown. Environ. Sci. Technol. 2005, 39, 7516-7528. Atmospheric Chemistry of Precursors 39. Dinglasan-Panlilio, M.J.A.; Mabury, S.A. Significant residual fluorinated alcohols present in various fluorinated materials. Environ. Sci. Technol. ASAP. 40. Ellis, D.A.; Martin, J.W.; De Silva, A.O.; Mabury, S.A.; Hurley, M.D.; Sulbaek Andersen, M.P. and Wallington, T.J. Degradation of fluorotelomer alcohols: A likely source of perfluorinated carboxylic acids. Environ. Sci. Technol. 2004, 38, 3316-3321. 41. Hurley, M.D.; Wallington, T.J.; Sulbaek Andersen, M.P.; Ellis, D.A.; Martin, J.W. and Mabury, S.A. Atmospheric chemistry of fluorinated alcohols: Reaction with Cl atoms and OH radicals and atmospheric lifetimes. J. Phys. Chem. A 2004, 108, 1973-1979. 42. Hurley, M.D.; Ball, J.C.; Wallington, T.J.; Sulbaek Andersen, M.P.; Ellis, D.A.; Martin, J.W. and Mabury, S.A. Atmospheric chemistry of 4:2 fluorotelomer alcohol (CF3 (CF2)3 CH2 CH2OH): Products and mechanism of Cl atom initiated oxidation. J. Phys. Chem. A 2004, 108, 5635 5642. 43. Hurley, M.D.; Misner, J.A.; Ball, J.C.; Wallington, T.J.; Ellis, D.A.; Martin, J.W.; Mabury, S.A. and Sulbaek Andersen, M.P. Atmospheric chemistry of CF3CH2CH2OH: Kinetics, mechanisms and products of Cl atom and OH radical initiated oxidation in the presence and absence of NOx. J. Phys. Chem. A 2005, 109, 9816-9826. 44. Martin, J.W.; Ellis, D.A.; Mabury, S.A.; Hurley, M.D.; Wallington, T.J. Atmospheric chemistry of perfluoroalkanesulfonates: kinetics and product studies of the OH radical and Cl atom initiated oxidation of N-ethyl perfluorobutanesulfonamide. Environ. Sci. Technol. 2005, ASAP. 45. Sulbaek Andersen, M.P.; Nielsen, O.J.; Hurley, M.D.; Ball, J.C.; Wallington, T.J.; Stevens, J.E.; Martin, J.W.; Ellis, D.A. and Mabury, S.A. Atmospheric chemistry of n-CxF2x+1CHO (x=1,3,4): Reaction with Cl atoms, OH radicals and IR spectra of CxF2x+1C ( 0 ) 0 2N 0 2. J. Phys. Chem. A 2004, 108, 5189-5196. 46. Sulbaek Andersen, M.P.; Stenby, C.; Nielsen, O.J.; Hurley, M.D.; Ball, J.C.; Wallington, T.J.; Martin, J.W.; Ellis, D.A. and Mabury, S.A. Atmospheric chemistry of n-CxF2x+1CHO (x= 1,3,4): Mechanism of the CxF2x+1C ( 0 ) 0 2 + H 0 2 reaction. J. Phys. Chem. A 2004, 108, 6325-6330. 000109 P-7 47. Sulbaek Andersen, M.P.; Nielsen, O.J.; Hurley, M.D.; Ball, J.C.; Wallington, T.J.; Ellis, D.A.; Martin, J.W.; Mabury, S.A. Atmospheric chemistry of 4:2 fluorotelomer alcohol (nC4F9CH2CH2OH): Products and mechanism of Cl atom initiated oxidation in the presence of NOx. J. Phys. Chem. A 2005, 109, 1849-1856. 48. Sulbaek Andersen, M.P.; Nielsen, O.J.; Toft, A.; Nakayama, T.; Matsumi, Y.; Waterland, R.L.; Buck, R.C.; Hurley, M.D. and Wallington, T.J. Atmospheric chemistry of CxF2x+i CH =C H 2 (x=1,2,3,6 and 8): Kinetics of gas-phase reactions with Cl atoms, OH radicals and 0 3. J. Photochem. Photobiol. A 2005, 176, 124-128. 49. Wallington, T.J.; Hurley, M.D.; Xia, J.; Wuebbles, D.J.; Sillman, S.; Ito, A.; Penner, J.E.; Ellis, D.A.; Martin, J.; Mabury, S.A.; Nielsen, O.J. and Sulbaek Andersen, M.P. Formation of C7F 15COOH (PFOA) and other perfluorocarboxylic acids during the atmospheric oxidation of 8:2 fluorotelomer alcohol. Environ. Sci. Technol. 2006, 40, 924-930 50. Waterland, R.L.; Hurley, M.D.; Misner, J.A.; Wallington, T.J.; Melo, S.M.L.; Strong, K.; Dumoulin, R.; Castera, L.; Stock, N.L. and Mabury, S.A. Gas phase UV and IR absorption spectra of CF3CH2CH2OH and FiCFzCFzkCHzCHzOH (x=2,3,4) J. Fluor. Chem. 2005, 126, 1288-1296. Environmental Monitoring 51. Boulanger, B.; Vargo, J.; Schnoor, J.L. and Hornbuckle, K.C. Detection of perfluorooctane surfactants in Great Lakes water. Environ. Sci. Technol. 2004, 38, 4064-4070. 52. Boulanger, B.; Peck, A.M.; Schnoor, J.L. and Hornbuckle, K.C. Mass budget of perfluorooctane surfactants in Lake Ontario. Environ. Sci. Technol. 2005, 39, 74-79. 53. Boulanger, B.; Vargo, J.D.; Schnoor, J.L. and Hornbuckle, K.C. Evaluation of perfluorooctane surfactants in a wastewater treatment system and in a commercial surface protection product. Environ. Sci. Technol. 2005, 39, 5524-5530. 54. Harada, K.; Nakanishi, S.; Saito, N.; Tsutsui, T. and Koizumi, A. Airborne perfluorooctanoate may be a substantial source contamination in Kyoto area, Japan. Bull. Environ. Contam. Toxicol. 2005, 74, 64-69. 55. Higgins, C.P.; Field, J.A.; Criddle, C.S.; Luthy, R.G. Quantitative determination of perfluorochemicals in sediments and domestic sludge. Environ. Sci. Technol. 2005, 39, 3946 3956. 56. Loewen, M.; Halldorson, T.; Wang, F. and Tomy, G. Fluorotelomer carboxylic acids and PFOS in rainwater from an urban centre in Canada. Environ. Sci. Technol. 2005, 39, 2944-2951. 57. Scott, B.F.; Macdonald, R.W.; Kannan, K.; Fisk, A.; Witter, A.; Yamashita, N.; Durham, L.; Spencer, C.; Muir, D.C.G. Trifluoroacetate profiles in the Arctic, Atlantic and Pacific Oceans. Environ. Sci. Technol. 2005, 39, 6555-6560. 58. Simcik, M.; Dorweiler, K.J. Ratio of perfluorinated concentrations as a tracer of atmospheric deposition to surface waters. Environ. Sci. Technol. 2005, 39, 8678-8683. 59. Sinclair, E.; Kannan, K. Mass loading and fate of perfluoroalkyl surfactants in wastewater treatment plants. Environ. Sci. Technol. 2005, ASAP. OOOiiO p.8 60. So, M.K.; Taniyasu, S.; Yamashita, N.; Giesy, J.P.; Zheng, J.; Fang, Z.; Im, S.H. and Lam, P.K.S. Perfluorinated compounds in coastal waters of Hong Kong, South China and Korea. Environ. Sci. Techno!., 2004, 38, 4056-4063. 61. Yamashita, N.; Kannan, K.; Taniyasu, S.; Horii, Y.; Okazawa, T.; Petrick, G. and Gamo, T. Analysis of perfluorinated acids at parts-per-quadrillion levels in seawater using liquid chromatography-tandem mass spectrometry. Environ. Sci. Techno!. 2004, 38, 5522-5528. 62. Yamashita, N.; Kannan, K.; Taniyasu, S.; Horii, Y.; Patrick, G.; Gamo, T. A global survey of perfluorinated acids in oceans. Marine Poll. Bull. 2005, 51, 658-668. Biological Monitoring 63. Bossi, R.; Riget F.F.; Dietz, R. Temporal and spatial trends of perfluorinated compounds in ringed seal (Phoca hispida) from Greenland. Environ. Sci. Techno!. 2005, 39, 7416-7422. 64. Bossi, R.; Riget, F.F.; Dietz, R.; Sonne, C . ; Fauser, P. ; Dam, M . ; Vorkamp, K. Preliminary screening of perfluorooctane sulfonate (PFOS) and other fluorochemicals in fish, birds and marine mammals from Greenland and the Faroe Islands. Environ. Pollut. 2005, 136, 323-329. 65. De Silva, A.O.; Mabury, S.A. Isolating isomers of perfluorocarboxylates in polar bears (Ursus maritimus) from two geographical locations. Environ. Sci. Technol. 2004, 38, 6538-6545. 66. Falandysz, J.; Taniyasu, s.; Gulkowska, A.; Yamashita, N.; Schulte-Oehlmann, U. Is fish a major source of fluorinated surfactants and repellents in humans living on the Baltic coast? Environ. Sci. Technol. ASAP. 67. Holmstrom, K, E.; Jarnberg, U.; Bignert, A. Temporal trends of PFOS and PFOA in Guillemot eggs from the Baltic Sea, 1968-2003. Environ. Sci. Technol. 2005, 39, 80-84. 68. Houde, M.; Wells, R.S.; Fair, P.A.; Bossart, G.D.; Hohn, A.A.; Rowles, T.K.; Sweeney, J.C.; Solomon, K.R.; Muir, D.C.G. Polyfluoroalkyl compounds in free-ranging dolphins ( Tursiops truncates) from the Gulf of Mexico and the Atlantic Ocean. Environ. Sci. Technol. 2005, 39, 6591-6598. 69. Kannan, K.; Tao, L.; Sinclair, E.; Pastva, S.D.; Jude, D.J.; Giesy, J.P. Perfluorinated compounds in aquatic organisms at various trophic levels in a Great Lakes food chain. Arch. Environ. Contam. Toxicol. 2005, 48, 559-566. 70. Kannan, K.; Yun, S.H.; Evans, T.J. Chlorinated, brominated and perfluorinated contaminants in livers of polar bears from Alaska. Environ. Sci. Technol. 2005, 39, 9057-9063. 71. Keller, J.M.; Kannan, K.; Taniyasu, S.; Yamashita, N.; Day, R.D.; Arendt, M.D.; Segars, A.L.; Kucklick, J.R. Perfluorinated compounds in the plasma of loggerhead and Kemp's ridley sea turtles from the southeastern coast of the United States. Environ. Sci. Technol. 2005, 39, 9101-9108. 72. Martin, J.W.; Whittle, D.M.; Muir, D.C.G.; Mabury, S.A. Perfluoroalkyl contaminants in a food web from Lake Ontario. Environ. Sci. Technol. 2004, 38, 5379-5385. 000111 P-9 73. Smithwick, M.; Muir, D.C.G.; Mabury, S.A.; Solomon, K.R.; Martin, J.W.; Sonne, C.; Born, E.W.; Letcher, R.J.; Dietz, R. Perflouroalkyl contaminants in liver tissue from east Greenland polar bears (Ursus maritimus). Environ. Toxicol. Chem. 2005, 24, 981-986. 74. Smithwick, M.; Mabury, S.A.; Solomon, K.R.; Sone, C.; Martin, J.W.; Born, E.W.; Dietz, R.; Derocher, A.E.; Letcher, R.J.; Evans, T.J.; Gabrielsen, G.W.; Nagy, J.; Stirling, I.; Taylor, M.; Muir, D.C.G. Circumpolar study of perfluoroalkyl contaminants in polar bears (Ursus maritimus). Environ. Sci. Technol. 2005, 39, 5517-5523. 75. Smithwick, M.; Norstrom, R.J.; Mabury, S.A.; Solomon, K.; Evans, T.J.; Stirling, I.; Taylor, M.K.; Muir, D.C.G. Temporal trends of perfluoroalkyl contaminants in polar bears (Ursus maritimus) from two locations in the North American arctic, 1972-2002. Environ. Sci. Technol. ASAP. 76. Tomy, G.T.; Budakowski, w.; Halldorson, T.; Helm, P.A.; Stern, G.A.; Friesen, K.; Pepper, K.; Tittlemier, S.A.; Fisk, A.T. Fluorinated organic compounds in an eastern Arctic marine food web. Environ. Sci. Technol. 2004, 38, 6475-6481. 77. Van de Vijver, K.l. ; Hoff, P .T .; Das, K .; Van Dongen, W . ; Esmans, E.L. ; Siebert, U. ; Bouquegneau, J.M.. ; Blust, R . ; De Coen, W .M. Baseline study of perfluorochemicals in harbour porpoises (Phocoena phocoena) from Northern Europe. Mar. Pollut. Bull. 2004, 48, 986-1008. 78. Van de Vijver, K.I.; Hoff, P.; Das, K. ; Brasseur, S. ; Van Dongen, W . ; Esmans, E . ; Reijnders, P. ; Blust, R. ; de Coen, W . Tissue distribution of perfluorinated chemicals in Harbor Seals (Phoca vitulina) from the Dutch Wadden Sea. Environ. Sci. Technol. 2005, 39, 6878-6884. 79. Verreault, J.; Houde, M.; Gabrielsen, G.W.; Berger, U.; Haukas, M.; Letcher, R.J.; Muir, D.C.G. Perfluorinated alkyl substances in plasma, liver, brain, and eggs of glaucous gulls (Larus hyperboreus) from the Norwegian arctic. Environ. Sci. Technol. ASAP. Eco-Toxicology 80. MacDonald, M.M.; Warne, A.; Stock, N.L.; Mabury, S.A.; Solomon, K.R.; Sibley, P.K. Toxicity of perfluorooctane sulfonic acid and perfluorooctanoic acid to Chironomus tentans. Environ. Toxicol. Chem. 2004, 23, 2116-2123. 81. Oakes, K.D.; Sibley, P.K.; Solomon, K.R.; Mabury, S.A. and Van Der Kraak, G.J. Impact of perfluorooctanoic acid on fathead minnow (Pimephales promelas) fatty acyl-coa oxidase activity, circulating steroids, and reproduction in outdoor microcosms. 2004 Environ. Tox. Chem. 23: 1912-1919. 82. Sanderson, H.; Boudreau, T.M.; Mabury, S.A.; Solomon, K.R. Effects of perfluorooctane sulfonate and perfluorooctanoic acid on the zooplanktonic community. Ecotox. Environ. Safety 2004, 58, 68-76. 83. Tominaga, N.; Kohra, S.; Iguchi, T. and Arizono, K. Effects of perfluoro organic compound toxicity on nematode Caenorhabditis elegans fecundity. J. Health Sci. 2004, 50, 545-550. 000112 Human Health References Peer Reviewed Journal Articles Human Exposure & Monitoring 1. Begley, T.H.; White, K.; Honigfort, P.; Twaroski, M.L.; Neches, R.; Walker, R.A. Perfluorochemicals: Potential sources of and migration from food packaging. Food Addit. Contam. 2005, 22, 1023-1031. . 2. Berger U, Ulf Jarnberg, Roland Kallenborn, 2004, Perfluorinated Alkylated Substances (PFCAS) in the European Nordic Environment, Organohalogen Compounds - Vol 66:4046 4052 3. Calafat AM, Needham LL, Kuklenyik Z, Reidy JA, Tully JS, Aguilar-Villalobos M, Naeher LP 2005 Perfluorinated chemicals in selected residents of the American continent Chemosphere. 2005 Oct 4; [Epub ahead of print] 4. Edward A. Emmett, MD, 2005 Press Release Penn Study Finds No Relationship Between Elevated C8 Levels and Liver or Thyroid Abnormalities Highest C8 Levels Found in the Very Young and Eldest. Univerisity of Pennsylvania Health System: News and Periodicals: News Releases. August 15, 2005. 5. Falandysz, J, S. Taniyasu, A Gulkowska, N. Yamashita, U. Schulte-Oehlmann. 2006. Is Fish a Major Source of Fluorinated Surfactants and Repellents in Humans Living on the Baltic Coast?. Environ. Sci. Technol., 40 (3), 748 -751,2006. 6. Guruge, K.S.; Taniyasu, S.; Yamashita, N.; Wijeratna, S.; Mohotti, K.M.; Seneviratne, H.R.; Kannan, K.; Yamanaka, N.; Miyazaki, S. 2005, Perfluorinated organic compounds in human blood serum and seminal plasma: a study of urban and rural tea work populations in Sri Lanka. J. Environ. Monit., 7, 371-377. 7. Harada K, Saito N, Inoue K^Yoshinaga T, Watanabe T, Sasaki S, Kamiyama S, Koizumi A. 2004, The influence of time, sex and geographic factors on levels of perfluorooctane sulfonate and perfluorooctanoate in human serum over the last 25 years. J Occup Health. 2004 Mar;46(2):141-7 8. Harada K, Inoue K, Morikawa A, Yoshinaga T, Saito N, Koizumi. 2005, Renal clearance of perfluorooctane sulfonate and perfluorooctanoate in humans and their species-specific excretion. A Environ Res Oct;99(2):253-61. Epub 2005 Jan 18 9. Inoue, K.; Okada, F.; Ito, R.; Kawaguchi, M.; Okanouchi, N.; Nakazawa, H. 2004. Determination of perfluorooctane sulfonate, perfluorooctanoate and perfluorooctane sulfonylamide in human plasma by column-switching liquid chromatography-electrospray mass spectrometry coupled with solid-phase extraction. J. Chromatogr. B, 810, 49-56. 10. Inoue, K.; Okada, F.; Ito, R.; Kata, S.; Sasaki, S.; Nakajima, S.; Uno, A.; Saijo, Y. Sata, F.; Yoshimura, Y.; Kishi, R.; Nakazawa, H. 2004. Perfluorooctane sulfonate {PFOS) and related perfluorinated compounds in human maternal and cord blood samples: Assessment of PFOS 000113 exposure in a susceptible population during pregnancy. Environ. Health Perspect., 112, 1204 1207. 11. Kannan, K.; Corsolini, S.; Falandysz, J.; Fillmann, G.; Kumar, K.S.; Loganathan, B.G.; Mohd, M.A.; Olivero, J.; Van Wouwe, N.; Yang, J.H.; Aldous, K.M. Perfluorooctanesulfonate and related fluorochemicals in human blood from several countries. Environ. Sci. Technol. 2004, 38, 4489-4495. 12. Karrman A, Bert van Bavel, Ulf Jarnberg, Lennart Hardell Gunilla Lindstrom 2004, Levels of Perfluoroalkylated Compounds in Whole Blood from Sweden, Organohalogen Compounds Volume 66 (2004) 4058-4062. 13. Karrman A., Bavel B., Jarnbuerg U., Hardell L., Lindstrom G., 2006, Perfluorinated chemicals in relation to other persistent organic pollutants in human blood, Chemosphere xxx (2006) xxxxxx. 14. Kubwabo, C.; Vais, N.; Benoit, F.M. A pilot study on the determination of pefluorooctanesulfonate and other perfluorinated compounds in blood of Canadians. J. Environ. Monit. 2004, 6, 540-545 15. Kubwabo, C.; Stewart, B.; Zu, J.; Marro, L. Occurrence of perfluorosulfonates and other perfluorochemicals in dust from selected homes in the city of Ottawa, Canada. J. Environ. Monit. 2005, 7, 1074-1078. 16. Kudo N, Iwase Y, Okayachi H, Yamakawa Y, Kawashima Y. 2005. Induction of hepatic peroxisome proliferation by 8-2 telomer alcohol feeding in mice: Formation of perfluorooctanoic acid in the liver. Toxicol Sci. 2005 May 11; [Epub ahead of print] 17. Kuklenyik, Z.; Reich, J.A.; Tully, J.S.; Needham, L.L.; Calafat, A.M. Automated solid-phase extraction and measurement of perfluorinated organic acids and amides in human serum and milk. Environ. Sci. Technol. 2004, 38, 3698-3704. 18. Kuklenyik, Z.; Needham, L.L.; Calafat, A.M. Measurement of 18 perfluorinated organic acids and amides in human serum using on-line solid-phase extraction. Anal. Chem. 2005, 77, 6085-6091. 19. Lau C, John L. Butenhoff, and John M. Rogers. 2004. The developmental toxicity of perfluoroalkyl acids and their derivatives; Toxicology and Applied Pharmacology 198 (2004) 231-241 19. Mawn, M.P.; McKay, R.G.; Ryan, T.W.; Szostek, B.; Powley, C.R.; Buck, R.C. Determination of extractable perfluorooctanoic acid (PFOA) in water, sweat simulant, saliva simulant, and methanol from textile and carpet samples by LC/MS/MS. Analyst 2005, 130, 670-678 20. Olsen, G.W.; Huang, H.-Y.; Helzlsouer, K.J.; Hansen, K.J.; Butenhoff, J.L. and Mandel, J.H. Historical comparison of perfluorooctanesulfonate, perfluorooctanoate, and other fluorochemicals in human blood. 2005 Env. Health Perspect. 113(5): 539-545. 21. Renner, R. The Manufacturing leftovers may help explain the puzzling presence of perfluorinated compounds. Environ. Sci. Technol. 2006, 40, Issue 3. 22. Tittlemier, S, John J. Ryan, Jay Van Oostdam. 2004. Perfluorinated Organic Compounds in Serum Collected from Northern Canadian Populations). ORGANOHALOGEN COMPOUNDS Volume 66 (2004) 4009-4014. 000114 23. Powley, C.R.; Michalczyk, M.J.; Kaiser, M.A.; Buxton, L.W. Determination of perfluotooctanoic acid (PFOA) extractable from the surface of commercial cookware under simulated cooking conditions by LC/MS/MS. Analyst 2005, 130, 1299-1302. 24. Washburn, S.T.; Bingman, T.S.; Braithwaite, S.K.; Buck, R.C.; Buxton, L.W.; Clewell, H.J.; Haroun, L.A.; Kester, J.E.; Rickard, R.W.; Shipp, A.M. Exposure assessment and risk characterization for perfluorooctanoate in selected consumer articles. Environ. Sci. Technol. 2005, 38, 3904-3910. 25. Wei Sheng Yan Jiu. 2004. Status of perfluorochemicals in adult serum and umbilical blood in Shenyang][Article in Chinese] Jul;33(4):481-3. 26. Yeung, L.W.; So, M.K.; Jiang, G.; Taniyasu, S.; Yamashita, N.; Song, M.; Wu, Y.; Li, J.; Giesy, J.P.; Guruge, K.S.; Lam, P.K.S. 2006. Perfluorooctanesulfonate and related fluorochemicals in human blood samples from China. Environ. Sci. Technol., 40 (3), 715 -720 Hazard & Toxicology 27. Butenhoff JL, Kennedy GL Jr, Hinderliter PM, Lieder PH, Jung R, Hansen KJ, Gorman GS, Noker PE, Thomford PJ. 2004 (a). Pharmacokinetics of Perfluorooctanoate (PFOA) in Cynomolgus Monkeys. Toxicol Sci. 2004 Oct 6 [Epub ahead of print] 28. Guruge KS, Taniyasu S, Yamashita N, Wijeratna S, Mohotti KM, Seneviratne HR, Kannan K, Yamanaka N, Miyazaki S.. 2005 (a). Perfluorinated organic compounds in human blood serum and seminal plasma: a study of urban and rural tea worker populations in Sri Lanka. J Environ Monit. 2005 Apr;7(4):371-7. Epub 2005 Mar 7. 29. Guruge, K., Yeung, L., Yamanka, N., Miyazaki, S., Lam, P., Giesy, J., Jones, P. and Yamashita, N., 2006, Gene Expression Profiles in Rat Liver Treated With Perfluorooctanoic Acid (PFOA), Toxicological Sciences 89(1 ):93-107 30. Han X, Kemper RA, Jepson GW. 2005. Subcellular distribution and protein binding of perfluorooctanoic acid in rat liver and kidney. Drug Chem Toxicol. 2005;28(2): 197-209. 31. Harada, K., Feng Xu, Kyoichi Ono, Toshihiko lijima and Akio Koizumia. 2005. Effects of PFOS and PFOA on L-type Ca2+ currents in guinea-pig ventricular myocytes Biochemical and Biophysical Research Communications - Volume 329, Issue 2 , 8 April 2005, Pages 487-494 32. Hinderliter, P, Eve Mylchreest, Shawn A. Gannon, John L. Butenhoff and Gerald L. Kennedy, Jr.. 2005. Perfluorooctanoate: Placental and lactational transport pharmacokinetics in rats Toxicology - Volume 211, Issues 1 - 2 , 1 July 2005, Pages 139-148 33. Lau, C., J. R. Thibodeaux, R. Hanson, M.G. Narosky, J.M. Rogers, A.B. Lindstrom, M.J. Strynar. 2006. Effects of perfluorooctanoic acid exposure during pregnancy in the mouse. ToxSci Advance Access published January 16, 2006 34. Perkins RG, Butenhoff JL, Kennedy GL Jr, Palazzolo MJ. 2004 13-week dietary toxicity study of ammonium perfluorooctanoate (APFO) in male rats. Drug Chem Toxicol. 2004 Nov;27(4):361-78. 000115 35. Saito N, Harada K, Inoue K, Sasaki K, Yoshinaga T, Koizumi A 2004. Perfluorooctanoate and perfluorooctane sulfonate concentrations in surface water in Japan. Occup Health. 2004 Jan;46(1):49-59. 36. Yang Q, Xie Y, Alexson SE, Nelson BD, DePierre JW. 2002. Involvement of the peroxisome proliferator-activated receptor alpha in the immunomodulation caused by peroxisome proliferators in mice. Biochemical Pharmacology, 63:1893-1900. 37. Yao X, Zhong L. 2005 Genotoxic risk and oxidative DNA damage in HepG2 cells exposed to perfluorooctanoic acid. Mutation Research/Genetic Toxicology and Environmental Mutagenesis Volume 587, Issues 1 - 2 , 1 0 November 2005, Pages 38-44. Risk Assessment 38. Butenhoff, J., Gaylor D., et al. 2004 Characterization of risk for general population exposure to perfluorooctanoate, Regulatory Toxicology and Pharmacology 39 (2004): 363-380 39. Butenhoff JL, Gaylor DW, Moore JA, Olsen GW, Rodricks J, Mandel JH, Zobel LR. 2004. Characterization of risk for general population exposure to perfluorooctanoate. Regul Toxicol Pharmacol. 2004 Jun;39(3):363-80 40. Butenhoff JL, Kennedy GL Jr, Frame SR, O'Connor JC, York RG. 2004. The reproductive toxicology of ammonium perfluorooctanoate (APFO) in the rat. Toxicology. 2004 Mar 1;196(12 ) : 9 5 - 1 16. 41. Committee on Carcinogenicity of Chemicals in Food, Consumer Products and the Environment, Nov. 16, 2005, The Carcinogenicity of Perfluroroalkyl Acids Perfluorooctane Sulfonate (PFOS) and Perfluoroctanoic Acid (PFOA), Food Standards Agency, Department of Health, U.K. 42. Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment, Oct., 2005, First Draft Working Paper on the Tolerable Daily Intake for Perfluorooctanoic Acid, Food Standards Agency, Department of Health, U.K. 43. Cynthia Bergman. 2004. EPA Press Advisory: EPA Takes Enforcement Action Against DuPont For Toxic Substances Reporting Violations News for release: (Washington, D.C. -- Thursday, July 8, 2004), Contact: Cynthia Bergman, 202-564-9828 44. Keerthi Guruge, Sachi Taniyasu, Nobuyoshi Yamashita, Shigeru Miyazaki, Noriko Yamanaka, Sumedha Wijeratna, Harsha Seneviratne, 2004, Perfluorinated compounds in human serum and seminal plasma from an urban and rural population in Sri Lanka ORGANOHALOGEN COM POUNDS - Volume 66 (2004) 4004-4008 45. Kennedy GL Jr, Butenhoff JL, Olsen GW, O'Connor JC, Seacat AM, Perkins RG, Biegel LB, Murphy SR, Farrar DG. 2004. The toxicology of perfluorooctanoate. Crit Rev Toxicol. 2004 JulAug;34(4):351 -84. 000116 46. Kropp T, Houlihan J. 2005. Human health risks from exposures to perfluorooctanoic acid: A critique of Butenhoff et al. 2004. Regul Toxicol Pharmacol. 2005 Jun;42(1):145. Epub 2005 Feb 24. 47. Ritetr, S. 2004. Polyfluorinated alcohols shown to be key source of bioaccumulating perfluorocarboxylic acids, C&EN WASHINGTON, 2004, FLUORINE PERSISTS June 14, 2004, Volume 82, Number 24, pp. 44-45 48. Renner,R .2005, Fluorinated compounds in the environment: More than PFOA, on line version ES&T September 21, 2005 49. Tittlemier, S., John J. Ryan, Jay Van Oostdam. 2004 Presence of Anionic Perfluorinated Organic Compounds in Serum Collected from Northern Canadian Populations, ORGANOHALOGEN COMPOUNDS - Volume 66 (2004): 4009-4014 50. Washburn ST, Bingman TS, Braithwaite SK, Buck RC, Buxton LW, Clewell HJ, Haroun LA, Kester JE, Rickard RW, Shipp AM 2005. Exposure assessment and risk characterization for perfluorooctanoate in selected consumer articles. Environ Sci Technol. 2005 Jun 1;39(11):3904-10. . 000117 Conference Presentations SETAC North America 2004 - Portland, OR Biological Monitoring Houde, M.; Bujas, T.; Balmer, B.; Wells, R.; Fair, P.; Solomon, K.; Muir, D.C.G. Perfluorinated compounds in three free-ranging bottlenose dolphin populations from southeastern U.S. waters. SETAC North America 2o Annual Meeting 2004, November 14-18. (Poster). Kannan, K.; Tao, L.; Pastva, S.; Jude, D.; Giesy, J. Perfluorinated compounds in aquatic organisms at various trophic levels in a Great Lakes food chain. SETAC North America 25th Annual Meeting 2004, November 14-18. (Poster). Environmental Monitoring 1) Kallenborn, R.; Berger, U.; Jaernberg, U. Fate and distribution of perfluorinated alkylated substances (PFAS) in the Nordic environment. SETAC North America 2&h Annual Meeting 2004, November 14-18. (Poster). 2) Johnson, B.; Olivero, J.; Kannan, K. Perfluorinated compounds in fish, birds and humans from Colombia. SETAC North America 2 ffh Annual Meeting 2004, November 14-18. (Abstract). Toxicology 1) Hoke, R.; Bouchelle, L.; Ferrell, B.; Buck, R. Comparative Acute Toxicity of Three Fluorotelomer Acids to Pseudokirchneriella subcapitata, Daphnia magna, and O ncorhynchus m ykiss. SETAC North America 25th Annual Meeting 2004, November 14-18. (Abstract). 2) Berti, W.; Wang, N.; Sulecki, L.; Folsom, P.; Buck, R. Bacterial Respiration Inhibition Studies of Fluorotelomer-Based Products. SETAC North America 25th Annual Meeting 2004, November 14-18. (Abstract). Atmospheric Chemistry of Precursors 1) Hashikawa, Y.; Kawasaki, M.; Sulbaek Andersen, M.; Nielsen, O.; Hurley, M.; Wallington, T.; Waterland, R. The Role of Photolysis in the Atmospheric Fate of Perfluorinated Aldehydes: Gas Phase UV and IR Absorption Spectra. SETAC North America 25Wl Annual Meeting 2004, November 14-18. (Abstract). 2) Ellis, D.; Martin, J.; Mabury, S.; Hurley, M.; Sulbaek Andersen, M.; Wallington, T. The Atmospheric Degradation of Fluorotelomer Alcohols. SETAC North America 25thAnnual Meeting 2004, November 14-18. (Abstract). 000118 Environmental Transport 1) Taylor, P.; Yamada, T.; Giraud, R.; Kaiser, M.; Buck, R. The Fate of Fluorotelomer Treated Consumer Articles in a Municipal Waste Incinerator. SETAC North America 25?hAnnual Meeting 2004, November 14-18. (Abstract), This work has since been published, see Taylor et al. Chemosphere 2005, 61, 974-984. Biological Transformation 1) Wang, N.; Szostek, B.; Buck, R.; Folsom, P.; Sulecki, L.; Gannon, J. Biotransformation of R e labeled fluorotelomer substances by microorganisms from activated sludge or soil. SETAC North America 25thAnnual Meeting 2004, November 14-18. (Abstract) Analytical Methods 1) Powley, C.; Ryan, T.; George, S. Matrix-effect free analytical methods for determination of perfluorinated carboxylic acids in environmental and biological samples. SETAC North America 2&h Annual Meeting 2004, November 14-18. (Abstract). 000119 SETAC North America 2005 - Baltimore, MD Analytical Methodology 1) Malotky, D.; Swanson, W.; Flaherty, J. The use of Isotopically Labeled Perfluorooctanoic Acid (PFOA) as a Quality Assurance Tool in Measuring the Effectiveness of Multi-Matrix Sampling and Analysis for Ammonium Perfluorooctanoic Acid (APFO). SETAC North America 2ih Annual Meeting 2004, November 13-17. (Abstract). 2) Flaherty, J.; Connolly, P.; Decker, E.; Kennedy, S.; Ellefson, M.; Reagen, W.; Szostek, B. Quantitative determination of perfluorooctanoic acid in serum and plasma by liquid chromatography tandem mass spectrometry. SETAC North America 2>hAnnual Meeting 2004, November 13-17. (Abstract). Environmental Monitoring 1) Helm, P.; Furdui, V.; Crozier, P.; Reiner, E. Occurrence of Perfluorochemicals in the Nearshore waters of the Laurentian Great Lakes. SETAC North America 2(fh Annual Meeting 2004, November 13-17. (Abstract). 2) Masunaga, S.; Odaka, R. Environmental behavior and mass balance of perfluorinated surfactants in Tokyo Bay, Japan. SETAC North America 2>h Annual Meeting 2005, November 13 17. (Abstract). 3) Huset, C.; Barofsky, D.; Field, J. Discovery of Semi-Volatile Fluoroalkyl Substances in Municipal Wastewater Treatment Plant Sludge. SETAC North America 2 ^ hAnnual Meeting 2004, November 13-17. (Abstract). Results were also presented at the Fluoros Symposium, see Huset et al. Fluoros International Symposium 2005, August 18-20. 4) Lucaciu, C.; Furdui, V.; Crozier, P.; Marvin, C.; Reiner, E.; Wania, F.; Mabury, S. A. Temporal Study of Perfluorinated Alkyl Substances in Niagara River Suspended Sediments. SETAC North America 2>h Annual Meeting 2004, November 13-17. (Abstract). Human Exposure & Monitoring 1) Nakazawa, H.; Kawaguchi, M.; Nakata, H.; Okada, F.; Inoue, K.; Ito, R.; Saito, K.; Saijo, Y.; Sata, F.; Kishi, R. Measurement of perfluorooctane sulfonate and related perfluorinated compounds in human maternal and cord blood samples. SETAC North America 2>h Annual Meeting 2004, November 13-17. (Abstract). SETAC Europe 2005 - Lille, France 000120 Analytical Methodology 1) Jahnke, A.; Temme, C.; Ebinghaus, R.; Ruck, W. Determination of airborne polyfluorinated organic compounds. SETAC Europe 15thAnnual Meeting 2004, November 14-18. (Poster). 2) Powley, C.R.; Buck, C.R. Matrix-effect free analytical methods for the determination of perfluorinated carboxylic acids in biological matrices. SETAC Europe 15thAnnual Meeting 2004, November 14-18. (Abstract). 3) Szostek, B.; Powley, C.R.; Prickett, K.B.; Ryan, T.W.; Buck, R.C. Methodology for the measurement of fluorotelomer B alcohols and perfluorinated carboxylic acids by LC-MS/MS in environmental samples. SETAC Europe 1 Annual Meeting 2004, November 14-18. (Abstract). Results are also presented in Szostek etal. J Chrom. B 2004, 813, 313-321 Biological Monitoring 1) Houde, M.; Bujas, T.A.D.; Balmer, B.C.; Bossart, G.D.; Fair, P.A.; Wells, R.S.; Solomon, K.R.; Muir, D.C.G. Tissue distribution of perfluorinated alkyl acids in bottlenose dolphins ( Tursiops truncatus). SETAC Europe 1 (r Annual Meeting 2004, November 14-18. (Poster). Results were also presented at the Fluoros Symposium, see Houde et al. Fluoros International Symposium 2005, August 18-20. 2) Van de Vijver, K.; Hoff, P.; Das, K.; Brasseur, S.; Reijnders, P.; Blust, R.; De Coen, W. Tissue distribution of perfluorochemicals in seals (Phoca vitulina) from the Wadden Sea: first measurements of perfluorobutane sulfonate (PFBS) in wildlife. SETAC Europe 1&hAnnual Meeting 2004, November 14-18. (Poster). Results have also been published in Environ. Sci. Techno!., 2005, 39, 6878-6884. Human Exposure & Monitoring 1) DeSilva, A.O.; Mabury, S.A. Constitutional isomer patterns of perfluorinated acids in human blood. SETAC Europe 15th Annual Meeting 2004, November 14-18. (Poster). Results were also presented at the Fluoros Symposium, DeSilva et al. Fluoros International Symposium 2005, August 18-20. 000121 Dioxin 2004 - Berlin, Germany Environmental Monitoring 1) Berger, U.; Jarnberg, U.; Kallenborn R. Perfluorinated Alkylated Substances (PFAS) in the European Nordic Environment. Dioxin 2004. (Short Paper). 2) Caliebe, C.; Gerwinski, W.; Huhnerfuss, H.; Theobald, N. Occurrence of Perfluorinated Organic Acids in the Water of the North Sea. Dioxin 2004. (Short Paper). Biological Monitoring 1) Corsolini, S.; Kannan, K. Perfluorooctanesulfonate and Related Fluorochemicals in Several Organisms Including Humans from Italy. Dioxin 2004. (Short Paper). 2) Guruge, K.S.; Taniyasu, S.; Miyazaki, S.; Yamanaka, N.; Yamashita, N. Age dependent accumulation of perfluorinated chemicals in beef cattles. Dioxin 2004. (Short Paper). 3) Sinclair, E.; Taniyasu, S.; Yamashita, N.; Kannan, K. Perfluorooctanoic Acid and Perfluorooctane Sulfonate in Michigan and New York Waters. Dioxin 2004. (Short Paper). Human Monitoring 1) Guruge, K.; Taniyasu, S.; Yamashita, N.; Miyazaki, S.; Yamanaka, N.; Wijeratna, S.; Seneviratne, H Perfluorinated compounds in human serum and seminal plasma from an urban and rural population in Sri Lanka. Dioxin 2004. (Short Paper). This work is explained in detail in Guruge et al. J. Environ. Monit. 2005. 2) Karrman, A.; van Bavell, B.; Jarnberg, U.; Hardelll, L.; Lindstrom, G. Levels of perfluoroalkylated compounds in whole blood from Sweden. Dioxin 2004. (Short Paper). 3) Tittlemier, S.; Ryan, J.J.; Van Oostdam, J. Presence of anionic perfluorinated organic compounds in serum collected from northern Canadian populations. Dioxin 2004. (Short Paper). 4) Yang, J.-H.; Kannan, K.; Kim, S.-Y.; Shin, l.-H. Levels of perfluorooctanesulfonate and related fluorochemicals in human blood from the general population of Korea. Dioxin 2004. (Short Paper). Analytical Methodology 1) Karrman, A.; van Bavel, B.; Jarnberg, U.; Lindstrom G. Development of a method for the analysis of perfluoroalkylated compounds in whole blood. Dioxin 2004. (Short Paper). Environmental Monitoring 000122 1) Taniyasu, S.; Yamashita, N.; Kannan, K.; Horii, Y.; Sinclair, E.; Petrick, G.; Gamo, T. Perfluorinated carboxylates and sulfonates in open ocean waters of the Pacific and Atlantic Oceans. Dioxin 2004. (Short Paper). 2) Yamashita, N.; Kannan, K.; Taniyasu, S.; Horii, Y.; Hanari, N.; Okazawa, T.; Petrick, G. Environmental contamination by perfluorinated carboxylates and sulfonates following the use of fire-fighting foam in Tomakomai, Japan. Dioxin 2004. (Short Paper). 000123 Dioxin 2005 - Toronto, Canada Environmental Transport 1) Loewen, M.; Halldorson, T.; Wang, F.; Wania, R.; Tomy, G. Altitudinal transect of atmospheric fluorinated organic compounds and pesticides in western Canada. Dioxin 2005. (Short Paper). 2) Cousins, I.T.; Prevedouros, K.; Buck, R.C.; Korzeniowski, S.H. Mass balance investigation of Perfluorooctanoic Acid (PFOA) environmental levels, emissions and sinks in the Northern Hemisphere. Dioxin 2005. (Short Paper). 3) Dinglasan, J.; Mabury, S.A. Residual Telomer Alcohols a Probable Source of Perfluorinated Acids in the Environment. Dioxin 2005. (Short Paper). 4) Kaiser, M.; Barton, C.A.; Butler, L.E.; Zaraecki, C.J.; Botelho, M.A. Perfluorooctanoate in air near a manufacturing facility fenceline: Comparing modeled and monitored values. Dioxin 2005. (Short Paper). Human Exposure & Monitoring 1) Tittlemier, S.; Pepper, K.; Tomy, G.; Chan, L. Examination of dietary exposure to polyfluorinated compounds via consumption of traditional foods. Dioxin 2005. (Short Paper). 2) Guruge, K.; Manage, P.M.; Miyazaki, S.; Yamanaka, N.; Taniyasu, S.; Hanari, N.; Yamashita, N. Species-specific accumulation of perfluorinated compounds in farm animals from Japan. Dioxin 2005. (Short Paper). 3) Shoieb, M.; Harner, T.; Wilford, B.; Zhu, J. Polyfluorinated telomer alcohols (FTOHs) in indoor dust. Dioxin 2005. (Short Paper). Similar results as presented at the Fluoros Symposium, see Shoieb et al. Fluoros International Symposium 2005, August 18-20. 4) Tittlemier, S.; Pepper, K.; Menard, C.; Moisey, J. Dietary Exposure As A Source of Perfluorinated Compounds For Canadians. Dioxin 2005. (Short Paper). 5) Gulkowska, A.; Falandysz, J.; Taniyasu, S.; Bochentin, I.; Okazawa, T.; Schulte- Oehlmann, U.; Yamashita, N. A possible influence of occupation and diet on level of perfluorinated acids in human. Dioxin 2005. (Short Paper) 6) Karrman, A.; Mueller, J.F.; Harden, F.; Toms, L.-M.L; van Bavel, B.; Lindstrom, G. Perfluorinated compounds in serum from Australian urban and rural regions. Dioxin 2005. (Short Paper) Analytical Methods 1) Taniyasu, S.; Kannan, K.; So, M.K.; Gulkowska, A.; Sinclair, E.; Okazawa, T.; Yamashita, N. A New Solid Phase Extraction Method for Short- and Long-Chain Perfluorinated Acids and Fluorotelomers in Water and Biota. Dioxin 2005. (Short Paper). 2) L'empereur, K.; Stadalius, M.; Connolly, P.; Flaherty, J.; Mansoori, B.A.; Zhu, Y.; Isemura, T.; Kaiser, M.A.; Knaup, W.; Noguchi, M. Method Validation of Two Methods Developed for the Low-Level 000124 Determination of Perfluorooctanoic Acid (PFOA) in Paper, Textile and Carpet by LC/MS/MS. Dioxin 2005. (Short Paper). (Note: A similar method is reported in detail in Analyst 2005, 130, 670-678) 3) Karrman, A.; van Bavel, B.; van Leeuwen, S.; de Boer, J.; Lindstrom, G. Perfluorinated compounds in human plasma and blood - 1st worldwide interlaboratory study. Dioxin 2005. (Short Paper). 4) Nakata, H.; Nakata, A.; Kawaguchi, M.; Iwasaki, Y.; Ito, R.; Saito, K.; Nakazawa, H. Development of an Analytical Method for Perfluorochemicals in Human Plasma and Blood by Liquid Chromatography-Tandem Mass Spectrometry Coupled with Solid-Phase Extraction Using a Column-Switching Technique. Dioxin 2005. (Short Paper). 5) Kennedy, P. Fast HPLC-TOFMS Analysis of Perfluorinated Organic Pollutants. Dioxin 2005. (Short Paper). 6 ) Taniyasu, S.; So, M.K.; Gulkowska, A.; Kannan, K.; Lam, P.K.; Yamashita, N. Optimization of Liquid Chromatography-Tandem Mass Spectrometry for Analysis of C4 to C18 Perfluorinated Acids and Some Fluorotelomers. Dioxin 2005. (Short Paper). 7) Tomy, G.; Halldorson, T.; Tittlemier, S. Methanolic extraction of poly- and perfluorinated alkyl acids from biota. Dioxin 2005. (Short Paper). 8) Van Leeuwen, S.; Karrman, A.; Zammit, A.; van Bavel, B.; van der Veen, I.; Kwadijk, C.; de Boer, J.; Lindstrom, G. First worldwide interlaboratory study on perfluorinated compounds. Dioxin 2005. (Short Paper). Similar results were presented at the Fluoros Symposium, see Lindstrom et ai. Fluoros International Symposium 2005, August 18-20. Environmental Monitoring 1) Lucaciu, C.; Furdui, V.I.; Crazier, P.W.; Reiner, E.J.; Marvin, C.H.; Wania, F.; Mabury, S.A. Temporal Study of Perfluorinated Alkyl Surfactants in Niagara River Sediments (1980-2002). Dioxin 2005. (Short Paper). 2) Rostkowski, P.; Taniyasu, S.; Yamashita, N.; So, M.K.; Lam, P.K.S.; Falandysz, J.; Lee, K.T.; Seong, J.; Im, K.S.H.; Giesy, J.P. Perfluorinated Compounds in Streams of the Shihwa Industrial Zone and Lake Shihwa, South Korea. Dioxin 2005. (Short Paper). 3) Nakata, H.; Kannan, K.; Nasu, T.; Cho, H.-S.; Sinclair, E.; Takemura, A. Perfluorinated contaminants in tidal flat and shallow water areas from the Ariake Sea, Japan. Dioxin 2005. (Short Paper). 4) Manage, P.M.; Guruge, K.; Taniyasu, S.; Yamashita, N.; Galbada Arachchige, S.P. Accumulation of perfluorooctanesulfonate and related fluorochemicals in fishes from Sri Lanka. Dioxin 2005. (Short Paper). 5) Crazier, P.W.; Furdui, V.I.; Lucaciu, C.M.; Stock, N.L.; Mabury, S.A.; Reiner, E.J. Determination Of Perfluorinated Alkyl Substances (PFAS) In Sewage Treatment Plant Effluents And Biosolids By Liquid Chromatography - Tandem Mass Spectrometry. Dioxin 2005. (Short Paper). 000125 Similar results where presented at the Fluoros Symposium, see Crazier et al. Fluoros International Symposium 2005, August 18-20. 6) Kurunthachalam, S.; Kannan, K.; Ohi1, E.; Koizumi, A.; Takasuga, T. Occurrence of Perfluorinated Contaminants in Water, Sediment and Fish from Kyoto Area, Japan. Dioxin 2005. {Short Paper). 7) Yamashita, N.; So, M.K.; Taniyasu, S.; Kannan, K.; Gulkowska, A.; Lam, P.K.S. Some case studies of local pollution by perfluorinated acids and fluorotelomers in Japan. Dioxin 2005. (Short Paper). 8) Simcik, M.; Dorweiler, K. Atmospheric Deposition of Perfluorochemicals to Surface Waters. Dioxin 2005. (Short Paper). 9) De Voogt, P.;' van Roon, A. Perfluorinated chemicals in sediments, particulate matter, soil and water samples from The Netherlands. Dioxin 2005. (Short Paper). Biological Monitoring 1) Tomy, G.; Halldorson, T.; Stern, G. Time trend studies of perfluorinated compounds in beluga (Delphinapterus leucas) from SE Baffin Island. Dioxin 2005. (Short Paper). 2) So, M.K.; Taniyasu, S.; Lam, P.K.S.; Zheng, G.J.; Giesy, J.P.; Yamashita, N. Perfluorinated acids in mussels and oysters from South China and Japan. Dioxin 2005. (Short Paper). Atmospheric Processes 1) Martin, J.W.; Ellis, D.A.; Mabury, S.A.; Hurley, M.D.; Wallington, T.J. Atmospheric lifetime and oxidation products of N-ethyl perfluorobutylsulfonamide (C4F9S02N (H)CH2CH3). Dioxin 2005. (Short Paper). Similar results were presented at the Fluoros Symposium, see Martin et al Fluoros International Symposium 2005, August 18-20. Physical Properties 1) Goss, K.-U.; Arp, H.P.; Bronner, G.; Niederer, C.; Schmidt, T.; Hertel, M. Partitioning behavior of fluorinated telomer alcohols and olefins. Dioxin 2005. (Short Paper). 2) Hori, H.; Hayakawa, E.; Yamamoto, A.; Yamashita, N.; Taniyasu, S.; Einaga, H.; Kutsuna, S.; Kitagawa, H.; Arakawa, R. Efficient decomposition of perfluorocarboxylic acids in water by photochemical approaches. Dioxin 2005. (Short Paper). Data is presented and discussed in Hori et al. Environ. Sci. Technol. 2004, 38, 6118-6124. 000126 Fluoros: International Symposium on Fluorinated Alkyl Organics in the Environment - August 18-21, 2005. Toronto, Canada Atmospheric Processes 1) Solignac, A; Mellouki, A.; Le Bras, G.; Yujing, M. The gas phase tropospheric removal of two fluoroaldehydes: C3F7CHO and C4F9CHO. Fluoros International Symposium 2005, August 18-20. (Abstract). 2) Sulbaek Andersen, M.P.; Nielsen, O. J.; Toft, A.; Ellis, D.A.; Martin, J.W.; Mabury, S.A. Hurley, M.; Ball, J.C.; Wallington, T. J. The atmospheric chemistry of perfluorinated aldehyde hydrates: A source of perfluorinated carboxylic acids. Fluoros International Symposium 2005, August 18-20. (Poster). 2) Martin, J.W.; Ellis, D.A.; Mabury, S.A.; Hurley, M.D.; Wallington, T.J. Atmospheric lifetime and oxidation products of W-Ethyl perfluorobutylsulfonamide. Fluoros International Symposium 2005, August 18-20. (Poster). (Note: This work has since been published in Martin et at. Environ. Sci. Technol. 2005, ASAP Dec 24,2005) 3) Ellis, D.A.; Martin, J.W.; Mabury, J.W.; Hurley, M.D.; Sulbaek Andersen, M.P.; Wallington T.J. The degradation of fluorotelomer alcohols in the troposphere. Fluoros International Symposium 2005, August 18-20. (Poster). (note: This work has since been published in Ellis e ta l. Environ. Sci. Technol. 2004, 38, 3316 3321.) 4) D'eon, J.C.; Mabury, J.W.; Hurley, M.D.; Sulbaek Andersen, M.P.; Wallington T.J. Atmospheric Fate of Af-Methyl Perfluorobutane suifonamidoethanol (W-MeFBSE, C4F9S02N(CH3)CH2CH20H). Fluoros International Symposium 2005, August 18-20. (Poster). 5) Young, C.J.; Muir, D.C.G.; Mabury, S.A. Atmospheric flux of perfluorinated acids into the High Arctic. Fluoros International Symposium 2005, August 18-20. (Poster). Environmental Transport 1) Higgins, C.P.; Handler, N.; Boehm, A.; Paytan, A.; Field, J.A.;. Criddle, C.S.; LuthyR.G. Potential role of sediments in determining perfluorochemical surfactant fate. Fluoros International Symposium 2005, August 18-20. (Poster). 2) Liu, J.; Lee, L. Solubility and sorption of 8:2 fluorotelomer alcohol by surface soils. Fluoros International Symposium 2005, August 18-20. (Poster). (Note: This work has since been published in Liu et al. Environ. Sci. Technol. 2005 ASAP) 3) Klasmeier, J.; Matthies, M. Evaluation of the environmental fate and exposure for perfluorinated telomer B alcohols. Fluoros International Symposium 2005, August 18-20. (Poster). 000127 4) Buck, R.C.; Kaiser, M.A.; Knaup, W.; Bose, W.; Schafer, T.; Thoma, B. Determining the fate of fluorotelomer alcohol and PFOA in the textile finishing process. Fluoros International Symposium 2005, August 18-20. (Abstract). 5) Korzeniowski, S.H.; Buck, R.C.; Cousins, I.T.; Prevedouros, C. Sources of perfluorocarboxylic acids in the environment. Fluoros International Symposium 2005, August 18-20. (Abstract). The sources and sinks of PFCAs in the environmental are discussed. This work is described in detail in Prevedouros etai. Environ. Sci. Technol. 2006, 40, 32-44. 6) Schultz, M.M.; Higgins, C.P.; Luthy, R.G.; Barofsky, D.F.; Field, J.A. Behavior of fluorochemicals during wastewater treatment. Fluoros International Symposium 2005, August 18-20. (Poster). 7) Waterland, R.L.; Gannon, J.; Kaiser, M.A.; Botelho, M.A.; Harding, T.W.; Ellison, G.B.; Vaida, V.; Tuck, A.F.; Murphy, D.M. Global transport of biogenic and anthropogenic surfactants on marine aerosols. Fluoros International Symposium 2005, August 18-20. (Abstract). 8) Paustenbach, D.J.; Panko, J.M.; Scott, P.; Unice, K. Retrospective modeling of potential residential exposure to perfluorooctanic acid (PFOA) releases from a manufacturing facility. Fluoros International Symposium 2005, August 18-20. (Poster). 9) Jahnke, A.; Temme, C.; Ahrens, L.; Ebinghaus, R.; Ruck, W . Determination of airborne polyfluorinated organic compounds in northern Germany. Fluoros International Symposium 2005, August 18-20. (Poster). 10) Berger, U.; Barber, J.L.; Jahnke, A.; Temme, C.; Jones, K.C. Analysis of fluorinated alkyl compounds in air samples from England. Fluoros International Symposium 2005, August 18-20. (Poster). 11) Stock, N.L.; Muir, D.C.G.; Mabury, S.A. Temporal trends of polyfluorinated sulphonamides and telomer alcohols in Toronto: Results of a long-term sampling campaign. Fluoros International Symposium 2005, August 18-20. (Poster). 12) Huset, C.; Barofksy, D.; Field, J Discovery of semi-volatile fluoroalkyl substances in municipal wastewater treatment plant sludge.. Fluoros International Symposium 2005, August 18-20. (Abstract). Physical Properties 1) Goss, K.-U.; Bronner, G.; Arp, H.P.; Niederer, C.; Schmidt, T.; Herte, M. Contributing to a better understanding of the partition behavior of fluorinated alcohols and olefins. Fluoros International Symposium 2005, August 18-20. (Abstract), 2) van Roon, A.; de Voogt, P. A mechanistic study of hydrogen bonding in fluorotelomer alcohol liquids. Fluoros International Symposium 2005, August 18-20. (Poster). 3) van Roon, A.; de Voogt, P. Vapour pressures of fluorotelomer alcohols. Fluoros International Symposium 2005, August 18-20. (Poster). 000128 4) Kaiser, M.A.; Botelho, M.; Cobranchi, D.P.; Kao,C.-P.C.; Krusic, P.J.; Larsen, B.S.; Marchione, A.A.; Wooler, G.R.; Buxton, L.W.; Buck, R.C. Physicochemical properties of fluorotelomer alcohols and perfluorocarboxylic acids. Fluoros International Symposium 2005, August 18-20. (Abstract). 5) Dumoulin, R.; Melo, S.; Strong, K.; Mabury, S.; Stock, N.; Hurley, M.; Misner, J.; Wallington, T.; Waterland, R. Laboratory measurements of the infrared absorption cross sections of fluorotelomer alcohols. Fluoros International Symposium 2005, August 18-20. (Abstract). Biological Transformation 1) Boese, W.; Ho, C; Knaup, W.; Koch, V. Biodegradation potential of a Clariant fluorotelomer- based acrylate polymer - Results from a test on inherent biodegradability (OECD 302B). Fluoros International Symposium 2005, August 18-20. (Abstract). 2) Wang, N.; Szostek, B.; Buck, R.C.; Folsom, P.W.; Sulecki, L.M.; Powley, C.R.; Berti, W.R. 8-2 Fluorotelomer alcohol microbial biotransformation pathways. Time for a paradigm shift? Fluoros International Symposium 2005, August 18-20. (Poster). (note: This work has since been published in Wang et at. Environ. Sci. Technol 2005 39 7516 7528.) '' 3) Berti, W .R.; Szostek, B.; Buck, R.C.; Schaefer, E.; Van Hoven, R.L.; Wang, N.; Gannon, J.T. Biodegradation studies of fluorotelomer-based polymers to assess their potential to contribute to perfluorinated carboxylic acids in the environment. Fluoros International Symposium 2005, August 18-20. (Abstract). ' 4) Dinglasan, M.J.; Mabury, S.A. Biodegradation of 8:2 telomer alcohol and 8:2 telomer acids under aerobic conditions. Fluoros International Symposium 2005, August 18-20. (Poster). (Note: This work has since been published in Dinglasan et al. Environ. Sci Technol 2004 38 2857-2864. )\ '' 5) Dinglasan, M.J.; Mabury, S.A. Evidence of 8:2 FTOH production from the biodegradation of 8:2 telomer methacrylate under aerobic conditions. Fluoros International Symposium 2005 Auaust 18 20. (Poster). ' 6) Fasano W.J., S.H. Korzeniowski, R. C. Buck and R.W. Rickard. Pharmacokinetics of 8-2 fluorotelomer alcohol in the rat 2005 Fluoros International Symposium 2005, August 18-20. (Poster). 7) Martin, Jonathan W , Scott A. Mabury, Peter J. O 'Brien. Metabolic products and pathways of fluorotelomer alcohols in isolated rat hepatocytes . 2005 Fluoros International Symposium 2005 August 18-20. (Poster). ' 8) Shabalina, I, Abedi-Valugerdi Manuchehr, Natasa Petrovic, Tatiana Kramarova, Jan Nedergaard, B Dean Nelson, Joseph W. DePierre and Barbara Cannon Comparison of the effects of ' perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA)on wild-type mice and knock-out animals lacking uncoupling protein-1 (UCP-1) 2005 Fluoros International Symposium 2005, August 18-20. (Poster). Biological Monitoring 1) Furdui, V.I.; Stock, N.; Whittle, D.M.; Crozier, P.; Reiner, E.; Muir, D.C.G.; Mabury S A Perfluoroalkyl contaminants in lake trout from the Great Lakes. Fluoros International Symposium OO01Z9 2005, August 18-20. (Poster). 2) Butt, C.M.; Stock, N.L.; Mabury, S.A.; Muir, D.C.G.; Braune, B.M. Spatial and temporal trends of ringed seals and seabirds (Northern Fulmar and Thick-Billed Murre) from the Canadian Arctic. Fluoros International Symposium 2005, August 18-20. (Poster). 3) Verreault, J.; Houde, M.; Gabrielsen, G.W.; Berger, U.; Haukaas, M.; Letcher, R.J.; Muir, D.C.G. Perfluorinated alkyl substances in plasma, tissues and eggs of glaucous gulls (Larus hyperboreus) from the Norwegian Arctic. Fluoros International Symposium 2005, August 18-20. (Poster). 4) Houde, M.; Bujas, T.A.D.; Balmer, B.C.; Bossart, G.D.; Fair, P.A.; Wells, R.S.; Solomon, K.R.; Muir, D.C.G. Tissue distribution of perfluorinated alkyl acids in bottlenose dolphins ( Tursiops tru nca tu s). Fluoros International Symposium 2005, August 18-20. (Poster). 5) Haukas, M.; Gabrielsen, G.W.; Hop, H.; Gulliksen, B.; Berger, U. Perfluorooctane sulfonate (PFOS) and related compounds in a Norwegian Arctic marine food chain. Fluoros International Symposium 2005, August 18-20. (Poster). 6) Gulkowska, A.; Falandysz, J.; Taniyasu, S.; Bochentin, I.; So, M.K.; Yamashita, N. Perfluorinated chemicals in blood of fishes and waterfowl from the Gulf of Gdansk, Baltic Sea. Fluoros International Symposium 2005, August 18-20. (Poster). Human Exposure & Monitoring 1) Holmstrom, K.; Berglund, M.; Jarnberg, U. Exposure to perfluorinated acids in 108 Swedish women in relation to methylmercury and fish consumption. Fluoros International Symposium 2005, August 18-20. (Poster). 2) Saito, N.; Koizumi, A.; Harada, K.; Inoue, K.; Inoue, S.; Yoshinaga, T.; Date, C.; Fujii, S.; Fujimine, Y.; Hachiya, N.; Hirosawa, I.; Koda, S.; Kusaka, Y.; Murata, K.; Nakatsuka, H.; Ohta, S.; Omae, K.; Shimbo, S.; Takenaka, K.; Takeshita, T.; Todoriki, H.; Wada, Y.; Watanabe, T.; Ikeda, M. Historical and geographic aspects of perfluorooctanoate and perfluorooctane sulfonate in human serum in Japan. Fluoros International Symposium 2005, August 18-20. (Poster). 3) Calafat, A.M.; Kuklenyik, Z.; Reidy, J.A.; Tully, J.S.; Needham, L.L. Perfluorochemicals in residents of the United States in 2001 through 2002. Fluoros International Symposium 2005, August 18-20. (Abstract). 4) Schlummer, M.; Gruber, L.; Ungewiss, J.; Fromme, H. Human exposure to perfluorinated compounds via food. Fluoros International Symposium 2005, August 18-20. (Poster). 5) Ehresman, D.; Olsen, G.; Tanaka, S.; Butenhoff, J.; Froehlich, J. A comparison of whole blood, plasma and serum evaluations for the determination of PFOA, PFOS, and PFHS in human subjects. Fluoros International Symposium 2005, August 18-20. (Poster). 6) De Silva, A.O.; Mabury, S.A. Linear and branched perfluorocarboxylate isomer distribution in human blood serum. Fluoros International Symposium 2005, August 18-20. (Poster). 7) Olsen, G.; Ehresman, D.; Froehlich, J.; Burris, J.; Butenhoff, J. Evaluation of the half-life (t1/2) of elimination of perfluorooctanesulfonate (PFOS), perfluorohexanesulfonate (PFHS) and perfluorooctanoate (PFOA) from human serum. Fluoros International Symposium 2005, August 18- 000130 20. (Poster). 8) So, M.K.; Taniyasu, S.; Lam, P.K.S.; Giesy, J.; Jiang, Q.; Yamashita, N. Monitoring of perfluorinated compounds in human breast milk from Zhoushan, China. Fluoros International Symposium 2005, August 18-20. (Abstract). 9) Strynar, M.J.; Lindstrom, A.B. Perfluorinated compounds in archived house dust samples. Fluoros International Symposium 2005, August 18-20. (Poster). 10) Tittlemier, S.A.; Pepper, K.; Tomy, G.; Chan, L. Examination of dietary exposure to polyfluorinated compounds via consumption of traditional foods. Fluoros International Symposium 2005, August 18-20. (Poster). 11) Shoieb, M.; Harner, T.; Wilford, B.H.; Jones, K.C.; Zhu, J. Polyfluorinated compounds in the home: levels in air and dust and human exposure. Fluoros International Symposium 2005, August 18-20. (Poster). Analytical Methodology 1) Hoppe, H.W.; Koster, H.D. Development of a new NCI GCMS method for the determination of environmental exposure to perfluorooctanoic acid and perfluorononanoic acid. Fluoros International Symposium 2005, August 18-20. (Poster). 2) http://www.chem.utoronto.ca/svmposium/fluoros/Ddfs/ANA007Malinskv.pdfMalinskv. M.D. Separation and detection of structural isomers of perfluorooctanoate (PFOA) in biological matrices: Solid phase extraction, volatile analog derivatization, and analysis using automated thermal desorption gas chromatography/mass spectrometry (ATD/GC/MS). Fluoros International Symposium 2005, August 18-20. (Poster). preclude 3) Wojcik, L.; Trojanowicz, M.; Szostek, B. Separation and determination of perfluorinated carboxylic acids using liquid chromatography with fluorescence detection. Fluoros International Symposium 2005, August 18-20. (Poster). (This work has been published in Wojcik etal. Electrophoresis 2005, 26, 1080-1088) 4) Szostek, B.; Van Hoven, R.L.; Berti, W.; Buck, R.C. Determination of 8-2 fluorotelomer alcohol, telomer-, and perfluorinated carboxylic acids. An analytical methodology for investigating biodegradation of fluorotelomer-based polymers in soils and sediment. Fluoros International Symposium 2005, August 18-20. (Abstract). 5) Ellefson, M.E.; Reagen, W.K. Comparison of ion-pairing, solid phase extraction, and protein precipitation sample preparation techniques applied to human serum and plasma for the analysis of fluorinated alkyl compounds using high performance liquid chromatography/tandem mass spectrometry. Fluoros International Symposium 2005, August 18-20. (Poster). 6) Powley, C.R.; Buck, C.R. Matrix-effect free analytical methods for the determination of perfluorinated carboxylic acids in biological matrices. Fluoros International Symposium 2005, August 18-20. (Abstract). ' 7) Powley, C.R.; Mawn, M.; Michalczyk, M.J.; Kaiser, M.A.; Huang, H.; Buck, R.; Korzeniowski, S. Analytical methods for the determination of extractable perfluorooctanoic acid (PFOA) from consumer articles. Fluoros International Symposium 2005, August 18-20. (Abstract). (Note: This data has been published in Powley et al. Analyst 2005, 130, 670-678) 000131 8) L'Empereur, K.; Stadalius, M.; Connolly, P.; Flaherty, J.M.; Mansoori, B.A. Zhu, Y.; Isemura, T.; Kaiser, M.A.; Knaup, W.; Noguchi, M. Development and validation of analytical methods for the low-level determination of perfluorooctanoic acid (PFOA) in paper, textile and carpet by LC/MS/MS. Fluoros International Symposium 2005, August 18-20. (Poster). 9) Taniyasu, S.; So, M.K.; Gulkowska, A.; Kannan, K.; Lam, P.K.S.; Giesy, J.P.; Yamashita, N. Trace level analysis for per and poly- fluorinated compounds. Fluoros International Symposium 2005, August 18-20. (Poster). 10) Lindstrom, G.; Karrman, A.; Zammit, A.; van Bavel, B.; van der Veen, I.; Kwadijk, C.; de Boer, J.; van Leeuwen, S. The 1st worldwide interlaboratory study on perfluorinated compounds in environmental and human samples. Fluoros International Symposium 2005, August 18-20. (Poster). Environmental Monitoring 1) Theobald, N.; Caliebe, C.; Gerwinski, W.; Huhnerfuss, H. Occurrence of perfluorinated organic acids in the water of the North Sea and Arctic North Atlantic. Fluoros International Symposium 2005, August 18-20. (Poster). 2) Barton, C.A.; Butler, L.E.; Zarzecki, C.J.; Flaherty, J.M.; Botelho, M.; Kaiser, M.A. Comparing modeled and monitored values: Characterizing perfluorooctanoate in ambient air near the fence line of a manufacturing facility. Fluoros International Symposium 2005, August 18-20. (Abstract). 3) Furdui, V.I.; Crazier, P.; Reiner' E.; Mabury, S.A. Direct measurement of perfluoroalkylated surfactants in Great Lakes water samples. Fluoros International Symposium 2005, August 18-20. (Poster). 4) Falandysz, J.; J^cek, L.; Rostkowski, P.; Gulkowska, A.; Taniyasu, S.; So, M.K.; Yamashita, N. Concentration of perfluorinated carboxylic acids in river waters supply to the city of Gdansk, Poland. Fluoros International Symposium 2005, August 18-20. (Poster). 5) Scott, B.F.; Spencer, C.; Mabury, S.A.; Muir, D.C.G. Polyfluoro and perfluorinated carboxylates in North American precipitation. Fluoros International Symposium 2005, August 18-20. (Poster). 6) Crazier, P.; Furdui, V.; Lucaciu, C.; Stock, N.; Mabury, S.A.; Reiner, E. Detection of perfluoro-alkyl compounds (PFCs) in sewage treatment plant (STP) effluents and biosolids by liquid chromatography - tandem mass spectrometry. Fluoros International Symposium 2005, August 18 20. (Poster). Toxicology 1) Hanson, M.L.; Sibley, M.K.; Boudreau, T.; Small, J.; Brain, R.A.; Mabury, S.A.; Solomon, K.R. Microcosm evaluation of the toxicity and risk to aquatic macrophytes from perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS). Fluoros International Symposium 2005, August 18-20. (Poster). 2) Van de Vijver, K.I.; Blust, R.; De Coen, W . Toxicity identification of perfluorinated compounds in the Western Scheldt Estuary. Fluoros International Symposium 2005, August 18-20. (Poster). 3) MacDonald, M.M.; Dinglasan, M.J.; Sibley, P.K.; Mabury, S.A.; Solomon K.R. Aquatic toxicity of fluorinated telomer acids. Fluoros International Symposium 2005, August 18-20. (Poster). 000132 4) McGregor, E.B.; Mabury, S.A.; Solomon, K.R.; Hanson, M.L. Microcosm assessment of the toxicity of 10:2 fluorotelomer saturated acid to aquatic macrophytes. Fluoros International Symposium 2005, August 18-20. (Abstract). 5) Frame, S.R., Butenhoff, J.L., Kennedy, G.L. and J.F. Hardisty. Pathology working group review of mammary glands from chronic feeding study in rats with APFO Fluoros International Symposium 2005, August 18-20. (Abstract). 6) Qazi M., Jasna Bogdanska, B. Dean Nelson, Joseph W. DePierre and Abedi-Valugerdi Manuchehr. Local activation of the innate immune system of mice by perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) 2005 Fluoros International Symposium 2005, August 18-20. (Abstract). 7) W ai Yin Yeung, Keerthi S. Guruge, Noriko Yamanaka, Shigeru Miyazaki, Paul K. S. Lam, Nobuyoshi Yamashita and John P. Geisy. Gene expression profiles in rat liver treated with pentadecafluorooctanic acid (PFOA) Fluoros International Symposium 2005, August 18-20. (Abstract). Regulatory Action 1) Kurias, J.; Miettunen, A. Progress on Environment Canada's ecological risk assessment activities for certain perfluoroalkyl compounds. Fluoros International Symposium 2005, August 18 20. (Poster). 2) Endres, F.; Koppenhoefer, J.; Schroeter-Kermani, C.; Schulte, C.; Widmann, K. PFOA - A project on hazard assessment under the OECD existing substance programme. Fluoros International Symposium 2005, August 18-20. (Poster). 000133