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BEST COPY AVAILABLE : psa : ANTWERP BLOOD TESTING RESULTS FROM JUNE, 1995 AHARDLELI E rReeLct 1. Purpose of the Blood Testing Blood testing for the presence of L0 rRa Program(BTP) Fc 95 (PFOS) and T1 ae FC 143 e mS r BdenerM sm h rsieSesRi oeee tTosTS asscT aie u Ln ceTeoe , o e Hh=sa easeit ecomets Rot E4 meH ns 1 E we ress lQeuveesltsi,onlniavierre f(usnecetiaotntactehsetds),,kibldonoedychefumnicsttiroinestes(tlsi,pibdlood SEdEyl emR , blood cell count, platelet count, differential counts), and ESSLEnTEesrmBEBee e E IRe RRn T e nts ev-- Meeer poe-- e blood count measured at ttheestUsniovnerasllitPyarticipants. Hormones were Co S BiEerEare E imeae EnE ESRaRnR IeE s iE i nnHEe Medicine and Pathology. StaonfdMairndniezseodtahorDmeootn.e aosfsLaavbokriattsory 04282 SPraualn.dardTihzeedmetehxtordacutsieodnincecthhniisaudeetGeervmeilnoapteieonbecornisiinscteedelof a aaESlca0.ec8(rhAnariiccncehu.eseTzuEuhsnmeev.siarboatsnnet.dtrratCachobtenuittoaivnmoi.naw-mavTsoaoinxtziihsuceonmal.rfaeon1aei4i:vov7nce1mee3as-si7ess1de7,iwniistt1s9hp8asol)Crs.dhiaTlhlis orevious testing, pSpeercftorrommaentcrey.liqTuhiidschtreocmhantioqaureahhavs-tbheeernmofsopurnadymrealsisable in EiSCoStgeDaopiire.nemhiinyyzgsahsi.tcbhiaeanEndmmieoedtloidocvaeclelrosacnaaeslnslldasytewenbotyritkaAhlenhltiycwsueterossrtyipoepmcoasraetniinronent.foefoasnssiptsostihte, 3w.ithDeasscsriispttainvcee rfersoumltsslant messaiverfliiied ia muoscoriiosih . PwPUiFhP3nOi%oiSc0sTshsiv:aaaiTlnbmoufiloeobeorirswmne.aaunstn.i1oTe.nhn8Tid3hwseampisaiorsxmgi.aam4vtuehcmreoruvmecaidele.utaecsse93laaizisesntdil3ini6vesitdcoeuefdaaslsissnn,epTiaa"irbitmlEieiEcisci1eipvfaafdttoerd - Grove and Decatur Slats is Listed in Aesecnierc OLA%e vTahleuehiwcahsest13.P2FOpSpmv.alue The mean was 9.9 ppm wPhFiOlAe vtahleuehiwgahses1t.1P3FpOpAm. Comparison distributions forCottage 1Apv5os5nl5ei5r%8,Be0aa%nn avavleourfesse11ooffyeiacnritsoe,arree`sattnteaivnsecmrloauycdieendgbiaonofsa1vsmerreaaegcenesut?iimOtef, ATiaifanvnasddecsraeaaailngoaeprsivoncsef;woarmuaSwztahed,rirtttiEleoncitkvbeasellrohpoceodfhrluoocnlwneceeltselitkoo,efnrceoa3uln'nrtoae,fveerf3re1ad5g3e%BSaiwtTes"iAsgMhctEeOloFlf, c11o66u33ntl,bibss., rTainpgee,. SL Tevedled only Shoradicteasttse:esanud rboiinclyhaUsaoClElilony TVlToeroobvaaercdslsska3(nBsr,yae2Omsp4UCe3TUcCt,tiievnneTdlchiylec)vaBtaiteccoehtelhsioetncarLteeilvoaentlisoofnosfhthiPesreeosmfplipocrevosesesaa'nacCupirrEroSennt FSFodoxnriFnPrriaosgst,eiabatauictok,naBraRonOudSnOdlcevlLeeulvbelwssaessasr4toe.hm0en3airnyooeumwtnadmatene0ri.ss3"55u3tpoeDmoubia0is0edddi,3no.ng oo in non-exsosed sone inBudiilvdiidnugal1s6),TeBvaeaclkeedrotuhnedhighest PFOA mean (2.8 ppm for 13 levels for PFOA are around 0.5 04263 i1JH3eo2.inodatoroajnsaBloiaymeb,e)u.tri1ed0ilTnahgSto0is34o3nhsahcdaiscethee`xtihhsoitscseheswsehtaennPirsvoeswaessxeavmmeairnnsesnlietlhZSes llsooonnggeesst: T14einnndi2vUiLd1udailnsG). 16e hwahdo tihnedihciagtheedstthPereonthseerseeslsongIeset noeoinmd fftooorrn RASoooaiefarnffe5aT3reetnmscooepobefeimnpiDecPraVFslOosArn.eallaitnhivotinhesehniAenn.tawnedTrhsietrwseoremkreafsmescttoosnnieaobnlioofoold,nloevtels FGEpraaasSno7duUsiRsRfeEr;LeYqFutoehrnetrtlehyowsveesr.oewrhtmohPooRlsOdaeSiufnwlfdheeeovrreeewlndascsththoneditrihnerfsreeesqocunlenottwlahyse.hseidcanttheir 05bgevatezaeEsla2tksieildno tcHooanshthaiecdntetrwhietPihFrOAcchloeofmtihPceFasOleSssin1ffiannrveoepnureoeasnnkciylCryb.dPiFdMOoSrneoltevseelesm fjohSHrdeelipnovaucitiodinu.taailsstvAoienosdriacBna,dte5nduimtnbhdeairtvsitdohufeaysdythoacgaseixspterienced the - OposortnoeosortnmaotarilocEslYihiDsvve,oeerur1ntstriveonesndtchsiiv,vf,iide4ud1a.iinnd1diiviviniddgsiesvsii;cdual : Diabetes mellitus, 1 indivlidual . Cswtotarramkneoerceoaihg*aehiennAiN2ctia%dtlshBi8PaFraOeApcraoenrldriemPliRanOtaSiroyfnosrmtaattnhreiicseensLtaiorrfevaazroiuapbleosf . FHSoohnmaeeDvvveeorst:s tiwhnhiisccehpnreworictaleolls,sbboe`ittsehefnottroitahldcoohmmeiuanltgttihmvaeepreascsbbilssosespstaaartsaistes(esTthsicemcoeavsnelterc.oo)nfd vvnaaalaulecu"IeHtisiaspttei1doO.nF Botsonriddl tohfe the WcshoairtmrlewelialstlCiiomorsonrhieoeclwaoctuuoistofrntiseam,oireitarcienmsuelatarireveaartihaaroteoeed Sesanomcipeenrrgoam:c)a-n8t.PFe-o)vrAaslaauntesdhieootfnhielteinscusamnbttehrasnoefa0tppiageiscesocseontiastsis(d(oLetcCoripaea)nd.tailotvnhseiisnb-this wTSfeeahaanor"ktifosrhciamttriiactoscneisat(iwaoinltishvea(:nsveeetnoazbfbvelmlteeohs)we)iabnslodfoiwocBdeersirrsea'ls'tiynilTaoels2uklawtlesi.enenoThesrteroanrae cSfljeiglncaittciiaoolnnscihomiononrsreosavhoueofeswn.sKcietd.`hnTaehtey wfiutmhctiingncyrseasiiznyegt rejarinciets is tPhPReFOOSlSatlatenevdre,lcsr,tehaektiidnnienye therefore of no - 04264 FfwToee2uvr0ae03g3f,aariSe,hioCnnoddthahBvePaFrSOeoArceaoniLdriekFleaOltSyioefnxoprmoascturhreiecsee.srouosf eviaraiaanbiltels, who eVmolEresEeheSxSo3srgsooosircuorimzeaeetli.aotnesdIntcwhliauttdheadPrReiOnXsitiohnneisttehiicsetanbsei:reosuA.alrknemaeliiiinnno"te othhoesroehaatraese should have jvSiaarrerinssaabiml,eaesl.iantiTohtOnehfsrehewiahwonieicrnihean,ldhiacvlaietteebdreaewtnuirtfeho.uanndyActasefihnhiceethhasostrsmohocionsireamntooinoens [BTIee2ta2wr5eiaed0nniStPhFiiOcoAanhacansed lit notefrviewgrlhyiccaehvhrooieiwdaseervseei.drn.(iccnerasseetes:ktiCTcoeselfa.it=ia.o4nt8s,thihnoises.0f0o0u5n)d. 4. erature and moression is likely to be a neihceemfeidnidoinng.or toxicoloay CCshrhaeet 7nt"ieClpo:sttoactgehereabmGlrevoavnleoPwaFenOrdA Sontzexoosu DaencdatPuFrO.S than the vAallsuee:s sfoorr other ojes ZAanxtiwmeurms vaarleuelsower onnoorttEtokmnoViwnnia.sdanraaeclhienrhAvntahtiiwseenreiss/siadstueemriyTnoiomraaa;cdtiiifncfgeespienecticsyotsiL0lOioPbrefoecueenlsdisenirgn gis - of these is PDhuaslideirnegr the case o3gfro(PonFseOuwAr.evasstd)o itnaketheplcaacsee seerenpitsosbendfobcuuisleddinign 16 1n - iC5Sos2oepbbeaeeosraeombsbsvviiooofnudsdipisrneocaboslmeepsmlseptreiensaeesnxctecreitnsasicnumreNrnetn)t twoorrkierdso (nwohticahppear aninal litperreasteunrte.which would be or coenictehrenr, arreelatthievres to the t2hpeorcae=daatzod FThaeerre are 5bteoinutdnhireveilbdalutoaeoldds ctwohheoPmriMosastvreoirespraanya A blelvoeolds.counHtosw,evetrh.ese nPToeReosp,setsiDidneaottfibhooelnevssiahriacnluroerfteinlotillvoyecrioersfuinfncoervseotelhieenJdibainiscosaretmeaDTdAhTistso.maecTptheveaprzees owtfeorebe fssessed in thiemomlueltciovrarreilaabtlieonss:malpriels, needlsittioesbeanfdurPtrhoenror 2S2adytyPiRsOeS.0thaenrve odfo tmhoet haovpemrasme.tomebaesurreelda.tionshins of p UUIsn2e:TteemI4s2V08oo4ffzstthhteeogbveeanretrciaoc)nisohiaednaetlrstchrisnpaairSa2m0ektinegrsasofwetlnle To palsanati,conoy - moren that thev currently 042s5 dTvmrohiesanktnitnheaieirnyhigTehhdiazswvoaeu4sn8mdocr2re5e1s.tt)hearn 3t12h04anaolfctho`entohselmcposaknirentgeiicrriaiacncesassidirnn dMiicnanteesodta, sDPoimoaenmtdienaggarinereta.hteesU.aSz1.e0-ac4n2ldeadprrrlioynbkashbilgpyheerrrewftelheeacnkt iFnuaocmieen)re,icchceiaunmnskitscoamplserto 5. Racomandations Dtbaehtieendgnigj2neabIed,oet.hoe sFsihsrossvte Sense hSIE Levels ofiofn7faoblrulm,ialtdiiitonngmsatkhe3esafnsodelnlc3o6ew,inn`dgsiJsmUuc5gc0atefsutritohnesr are paEofEsesrLilbyialnutineioytroaCrlhmilsy 1di8insdoatifnrviiPobdRpuuOttaMielodanhn.aydvceiPerrnoets,h.esiiInntcemwooitrnheles"mcoairlneylrltrethtsisswhearde rexppoossuursee.sTM Of Bot only respirablOef ecxopnocseurrnewoeeirli,fthsekin - EnB"odiahievaniiviaeaead.pbtreoolcdikhiSetErlikopeenfrvasuslanafdnodrthtteohepolppaelnnatnutEpatytoehseschdeaiirene)sotdaiiss,biebnetfwoermeantion IiSnonfxotimaamnaattsoiTb)iYsn,rTi4uoDddiiocensguopliltdnyhag,attewsiaatypi.pnheaaTsragbaienrsdhthgceoaraiptnreocisimbrpooerrit'asnl(thuttmhoaepniOcosr. PPAroneftcoesrnnntiaiitiiaoo;bnleStomhtshaa,th Potential c wwaoolrrtkkhieonrugsghwniepterhdesIttuthom'eessfd,oilLmaipOsooLsrstehaiewarririthcdolsuatrfehleuatmyyanthe hemical exposure, cours with any PFeoDorerrlfkksopbmPearasactcctioi$fYc7,eetThYis10tawtshsyeeesaUssSm..e"nptlaIsnfhtosbu,elcdo"tmbheeisus nmedereeri'taakkeenn,is workers. and facilitates fomeon Communiciamteinotnexwpietchted mfGSeaayrrsssii,otmoaeDmsseeedUnSEt.dooreSsiWEcdeKreiEnbaTterSiefyiensdtiatshbeelaisfselhsuionitgocafhledumioisreeoesc)sheepaisiiucnrraveletillTahnicse is doooets CSolmaaitms t1tah9ne,2se52,i8sf5su1ur0etshd,Ue"sr1ii7ennnthadhaneenifycmeeana)dooiusnerugoisnthsei!st"itAylTttteyrinesaxtpuiesvdewedioleryank,stelrtyashiftsihnadt SShhoouulniiddngbbyeLesExihpmoliUolrGaeErd ttiohnetfhBuiesritghwiesormusddeerbgeeiiilpingsiSCooonmp=at8nhyyerpaerg.oahiinTbshittisftahlisse, - C4286 phmlehareceeeTbioelvfteoirrveatzhtiehaitnseexpstrtoafjteeiwcsttwieciesaklsc.oamnoallevrsee.s nTeheadt tsohobuelfdinbaelitzaekdinc 2f0o%cusoxoDnecttheed tliovearltefrunctthieonabotevsetscT,ohemperanidtmdsia.tciiolnmnaesls senfaflovrsteswialrle JrOaneteheefnriainSnalgwiantonhtdoeu.sthivaIotsiinsnghaolpuerlodcerebrseosrem.sentfiroomneAdntteheactp trheeMibnlonoedsota SC2Eh,nadt atnhaoelfypzlteahdenthfelpruaeorrtwoiiccthihevomauittciaoaln lofsosr. thAAiLsdLdisttfuifnoeennsaslwlwevar,so ctiohtlelaehpcipcteheaerdsst nPeaesedo to hbee cDoenoanrlaetuwlhaotehdelooneda weiixotabhm tprhoicssaesfef:orien well gene itnheAnrtewceernpt Pcolmemaesnetsfetelhatfryeoeu tmoaycahlalvee.ither of us with any questions or AJsesfofcrieayteH.MeMdaindceall, DMi.rpe.c,toMr.P.R. - PJreoajnecBturrCios-,ordRi.nN.a,torO.H.N., M.p.u. 11/6/95 04287 t ~ ampreyn ase ` October 10, 1995 0: FROM: Jeff Mandel, TTuo3o,5tPypeo8s,OfS8% 0 M. D., 3M fluorine Medical Department this year nas hPPoemer. mTii4hp.Ji05snsp))ec1o4fn3ld,oupoirreeYisAonuvuelertrwsamegereaesfumorereadspuelroeepvdleel wreien fibresetn coonmepleted. SIS PPT (parts me yma Plant was ppm. 2% PPR. The averagweasfofrorpeFceplsesarJwousmPelaasnutrewdasle1v1..e55l e cCvhhieemomiucIasRlEs,l.eUvePlSvTaAsRgTreTaetdeirnttihnagn a8neppmh,anlSlogshooulud,lcd hcheeck ( ' EPpeixsorpnoaitpiiiec.caSntocinevEoLIefnn.etththeo Bgliovoed'yloeuveflese.dbpacokreasbohuetaltthhe - BLYSa2T0oa0Edu)lisiJCnuYgpneuepaeraYasvtdieitstYBohrrPosrppoetecienraftuiehaytleoieouoscnnehsteaeirvwinxehoeaepn,nnoelyvwaseedgrui'iureerbsesooi:errIossiicnn#otdemeceaonbmodpuCiothnuegnscadktfshewauitgtehall \ 04288 DistributionFOlfuFoCr9i5neVaTlestResults ' Cottage Grove-1995,Antwerpu-e1s9a9t5T,harnedeLDocations; ecatur-1: 994 I Th mp-- Croell oe o e REE g elyi i i peETEo gs W = fee ) 2 nr 3 CotDtiasgteriGbruotivoen-1Fo9lf9uF5oC,r1Ai4nn3tewVeTarelpsy.teR1ge9g9s5u,TlhatrnsedeDLeoccaattuirons: -1994 } Po IF Ae Ry CHE i l| f i TRA a] SefluDesir em lS ETR R Rfge = = m| f BE1E .dTaEAl R i SBT S H | Ik R HuEdi IA T RN a. g : CT rEEiI Tei re 2 Fas IM MedicalDepartment dg - woe 8 Altwerp 1995 Fluorachemical Study g Err He vem Table 1 =s feree eee fe = --F a RE emma omme= our ae om oharoe n pe -- aA---- -- =: isons ' ee ee ------ aTH aa e IC ea -- 12 rr] 5 . ELGee--r: om T{ amp= ee e-- = SF rea Fhe] we EE -- g4z71 Compt meme Amin Rly ce warrE esis ses emi osoun [rseour 1 Ober nwouts)wipt ee 3- 8 x 199aPr CohrbyacDeprahrtasceesAtEpteas ee [. me : Tube g g = = = E BESTCOPY AVAILABLE Aree 1935 Pech Sut - ALEmpl Tabi 4a foom----Terr . -- I --oe] fT or om e-- m e -- y e] Et EfE-- -- eEo LLTY-- -- -- ----1=A ---- ------------ -- foe ----=f--e -- afe] -- w ----e ee r e o . pe e w ege -- fo-------- =e= w ] pram ee peer EE -------- -- [ EY r --= -- dE we ---- ] : 04273 SESTCOPY AVAILABLE "rCa orrelationSr~aAdllayy"ree Tables Ef-- F rE--------a---- a . oanr -- T --rioo r] pcoer em eemr | Ee wm | 5 f-- e ----em----=a I [h-- I ems-- iopber-- -- -- a---- o m r-- mr }---- -- ] -- [e--m-- s ------------as--m------] mew [ep ms a] om -- -- 1-- -- --] O-- -- E ---- T-- ---- 5]5--] s: r ~ E f -- e-- e F---- -- =en-- l-- --f -------- f -- -- --S e 4 ee--r-- ------------ ------ eww at er fr---- Ye ------ = -- am ELI a -- Ee e-------- wm-- E= E -- -- --Tar 4274 BEST COPY AVAILABLE: 155Fleorchemica Sud ~Menwith Hormone Testing Tou TableSA ] FTse -- EE ---- I------ -- so a s eomrm [ ----e ----s ae g fg ] ------+----=] fe fm = -- or ----=] om ------ --e ---- o -- r---- -- ---- SE : -- ae er -- = EE -- p EE -- =-- wy-- --em]7 Ee -- - 04275 BENyST COPY AVAILABLE Antwerp 1995 FioorochemicaCloSrtruadiyo~nsMaleswwiitthh Hormone Testing "Table 5B [F C-- ompram-- 0 0 : -- orwIm ToB mrenon -- coe eflicir ent| fos = w=w = ] I E-- e -- e-- e-- -- e1 s -- -- --|-- -- pessoa fre--------1e-- e ---- I-- -- -- --o-- r ------ . ) E-- E r-- e-- Ia Spm-- ---- I -- [Eri -- ---- -- a see--g ---- | I ------ -- [-- er -- g E I e-- ---- ---- ------ ]m-- -- ------ sa -- ------ ra ---------- ag war 04276