Document 6b7EjqvnYD3JXXmGnO9L4o9vR

r xxxxxxxxxx t K - {lealtli Services and Mental Health Advunistration .' Hooai 409, Federal Office bldg, 5SQ Main Street National Institute for.Occupational Safety and Health September1 9, 1971 V Dr.' Leo Grant Pittsburgh Plate Glass Co. One Gateway Center Pittsburgh, Pennsylvania 15222 Dear Dr. Grant: NOTE: Tr NOT Cuyit :. .. , PvCfcrrii's to our conversation on .Tuesday concerning tho concentrationti?.TiCS'time relationship of asbestos dust exposure to clinical changes, I would like to quote frora a recent publication of the National Air Pollution Contx*ol Administration,* which states: "Aobastccis usually develops -after Ion? exposure to high concentrations of dust. The risk varies directly vith the length of exposure and dust concentration. Following continued axnosuro to high 00000011x111005 of dust, asbestosis nay develop fi!lly in 7 to 9 years and >:ay cause death ns early nr. 13 years from onset of exposure." Other articles that show this ccnccntration-tir.-os-tiao relationship ere cs follows: 1. Lanza, A. J., McConnell, 17. S., and Fthnol, J.: Effects of the Inhalation of Asbestos Dust on the Lungs of Asbestos Workers, lhiblic Health Reports, 50, 1935, 1, ... 2. Dreesen,. N. C,, Dallavalle, J. M., Edwards, T. L., Miller, J. if., end Sayers, U. P,,: A Study of Asbestosis in tho Asbestos Toxtile Industry. Public Health bulletin *241, U, S. Treasury Departrnont, Public Health Service, Washington, D, C., 1930. 3. ' Gaansior, Edward A., and Kaplan, Alfred X.: Asbestos Pleural Effusion. Annals of Internal Medicine, Vol. 14, No. 2, Fed., 1971. 4. Hunt, Poss: Routine Luna Function Studios on 839 Employees in ' Asbestos Processing Factory. Annals of the New York Acadcay of Gcionces, Voi. 132, Art 1, Pago 405, 1905. Killians, Pogei* and Hugh-Jonos, P.: Tho Significance of Lui:g0<' Function Changes in Asbestosis, Thorax, Vol, 15, 109, lD6rD^9.^pvb 6. Solikeff, I. .7. and J. Chur?, end ii. C, Karrrond, 'fl:0^ of Asbestosis Ar-cnr' Insulation Workers in tho JgswnjcSv Ann# N. Y. Acad. Sci. 132: 135 (1965). ^5.^'* iS T~B~D~ 00 2 4 as"1 \ x. \ \ Dust concentrations in these articles represent similar concentrations to those found in the Port Allegany plant by tho United States Tublic ljealth Service. As you can end will see these articles indicato that the clinical char.res, which occur with exposures of less than seven years duration arc consistent with Asbestosis; If yoxi have any other questions concerning this relationship please feel free to contact no. Sincerely yours. Richard A. Lemon Sanior Addistaat Sanitarian .Division of Clinical Investigations and Field Studies Sullivan, Ralph J. and Athnnassiadis, Yanis C.: Preliminary Air Pollution Survey of Asbestos - A Literature Review. National Air Pollution Control Administration Publication Ko. APT!) 63-27, October,,TM 1909 . 4,,,-'aVT V'\ rTM s. . ; ^ V''; i cc: Mr. David L. Cayliss Dr. Killian Johnson Dr. Joseph Wagoner ^CVrVV-,'-.. , . v> -& i#5' | BB 0024968 |