Document 6Rq5q1wrykqLKp6QB10JLOpEg

00* Nr. F. B. Hanrahan Dr. V. B. Aokart Nr. J. C. Fryman `- October 29, 1998 Dr. Paul 0. Lauffer Dlrootor of Research Northern Varron Corporation Barry Flaoa Stanford, Connectlout Rat "Bakellte* Vinyl Butyral Saaln XYHL Dear Dr. Lauffer* X have boon requested to write to you regarding this realn which X an informed you propose to use in a fingernail polish formulation. Coatings from vinyl butyral rosins have been used In applications where they eame In oontaot with the skin. A Military Specification has been written for waterproof bed sheets whloh specified vinyl butyral resins. In addition, a report by Dr. A. J. Lehman, Chief, Division of Pharmacology, Food and Drug Administration, re printed from the QUARTERLY BULLETIN OF THE ASSOCIATION OF FOOD AND DRUG OFFICIALS OF TUI UNITED STATES, Vol. XX, No. 4, October, 1956, lists polyvinyl butyral resins as acceptable for food packaging. From this Information we believe it la safe to assume that "Bakellte* vinyl butyral resin XYHL la extremely Inert physiologically and would not be expected to act as a skin Irritant or skin sensitizer. As a manufacturer of nail preparations, you are aware of the mechanical effects of complete ooeluslon of the nail surfaoe with some materials whloh are completely imper vious* We would assume that your company would establish ucc 063211 ue u*.j INTERNAL. CORRESPONDENCE BAKELITE COMPANY To (Nam*) Company loofen Dr* T. V. N&I* 60 E. U2nl St. Room 920 30 EAST 42nd STREET, NEW YORK 17, NEW YORK October 28, 1958 Onginoifeo 0p# copy in Mr. j. c, Fryman Subjod This letter is being written in reference to our phone conver sation today. Dr. Paul G. Lauffer, Director of Research at the Northam Warren Corporation, Barry Place, Stanford, Connecticut, has requested us to make a statement on the effect of vinyl butyral resin UHL when in contact with the skin. Dr. Lauffer1 s company plans to use XIHL in a fingernail polish formu lation so their concern is understandable. After consulting the information available in the office here. I believe we can make the following statements to Dr. Laufferi Coatings from vinyl butyral resins have been used in applica tions where they came in contact with the skin. A Military Specification has been written for waterproof bed sheets which specified vinyl butyral resins. In addition a report by A. J. Lehman, Chief, Division of Pharmacology, Food and Drug Administration, reprinted from ASSOCIATION OF FOOD AND DRUG OFFICIALS OF THE UNITED STATES, Vol. XX No. U, October 1956; lists polyvinyl butyral resins as acceptable for food packaging. From this information we believe it is safe to assume that Bakelite Vinyl Butyral Resin XXHL is extremely inert physiologically and would not.aotr as a skin irritant or be * skin sensitizer. ie above statement will satisfy Dr. Lauffer. It would be appreciated if a carbon copy of this letter could be sent to Mr. J, C. Fryman at the Larchmont Office of the Bakelite Company as Mr. Fryman will be handling this account. Mr. Fryman's address 1st 1877 Palmer Avenue Larchmont, New Tork Mi appreciate your willingness to supply this information to Dr. Lauffer. F UCC 063212 Or* Faul 0* lauffor 2 Motor 29* 195 tto safety la uu for /our final produst containing XYHL. Our naturally appllos only to XYUL ltsolf. Vary truly yours. Thoaas W. Sals, N, 0* ah mOZCAL DIRECTOR ucc 063213