Document 6RKjoeEpaw6NYagBDoER69JVm

Mr. W.W.F. Shepherd, T. 4 N. Ltd. . T>m-j t bns n-ii* r,-< :.. : v vt . -10th July, 1543 Dr. Leroy U. Gardner's Aabeatos ................Duet ggpcriments.- - In oonnootion -with your note' of- 3rd July, I am now sending .you & copy of Dr. Francis's comments on Dr. Gardner's letter, and you may think it would he worth while to forward them to America. : - * . ..u-. .: R. G-, fo thill V- th Jaly, 1543 ,ccasm ca ra. lssdt u (mesa's izstzs to eg. Tigprrg ascsg czr tes jcars^cmn^a coapcaAgioa, ana 5s juib 1943 Tbo first point in the freqpeeay of the incidtraos of tuberculosis with asbasteals in Zn^Land and tha relative inf^oqaoaoy of tuberaulaE. infection in. asbestos workers in the U.S.JL , . * ,i v;. ^1, . . , I' 3 41 -* J .* % . Hr. Gardner icon act appear to. -approoiata ths* paint that 1a Bcglaal ; poetnorteoi *xa*ira.tio2s era carried ostia tfce case.'of all death* of fcrscr - asbestos veriera ro have been certified as enffarissj from ths ooaplaint, chathsr thoy die in institutions cr sort. Ceossmteatly atcae 1531* when tha regulations asbetrtcaia an industrial dinsane ossa into fcrco, tbs statistlea in l&sbials * and presumably throughout tbs country, eraccopleto and shoo, that a. high proportion ef deaths ef^certified.anbaatenla_-caces. la.too.to palssaiejr/ tuberculosis, acoalsratod by"eobsstoois.. er Pith.asbestosia as o .fcntrifcotcry caniw. In rso oaaa where pcstnarta* assniraticav has been radt has death bean shown to be dns to achesteals alesa, fcset-death is nnaalljr das to. seas pul nonary -- ooaplaist each as bronchitis, or n asaoeiatod-- vith-esbestesia. - ' Thsre ars cevarjl case* in yhish cancer has ?ri:<*.3cl shoos. -. to ba a contributory u. v`J i;,, o': V* da cot as yet, in thin district, carry eat X-ray surreys ef large (reaps of asployees, bat after the car this say bo possible and Dr. Gardner's point trill than ba alearad op finally. fleanubile I think we oast accept the fact that in this district at least tuberculosis la often aunpointed with fibrosis duo to aabastoe. Proa Ua wit^a by Dra. Xing and Balt far as, we can agroo that in experiments tubercnloais is not usually associated with fibrosis duo to asbestos. .. , Tha suggestion that Cr. Xcmsther's cases af tuberculosis in asbostoo tottars ocoorred in ths aasa feanily because fire ef tha subjects bad tho saxa na again is probably due to Dr. Gardner's tmfwsil jarlty vith conditions in Sag!and. In thin district, for ezsarpla, certain aoraaaas ccour vith sraat frequency, .( iahaorth, Battarvcarth and Cl(g, vhllst in Vales samnanaa such as Jonas, Sraas, Darios and Own prsdaadnato, so that it aassot bo assanod that people with tbs sasa nwt' are aloaaly related', at' least. In recent generations. Tha incidence cf tobereoloais in Krylrad nay, cn tbs othsr band, be issodstod vith olissatio oanditlons, ainea car tsxtlle fnetcries or* situated 1a areas previously found fsrearahlA for textile processing, eg. in Lancashire, vhara the olineta is cold and dap. Tbs reverse is ths ease in Amrica, vhsre Boat of tbs asbostos textile factories are situated in the Sea torn States, vith a dry cllaato in sumr sad winter. Vith regard to the effect af alrainira and alanine, the aheadcal work that w hare undortaksn soggssta that aluzainirsa is acre effective in ssppressi tha solubility ef asbestos in Binger's eolation than alinim. fa have exrsirsd sewral types ef Mtirstad acd eolleidal alunrlnas and pondered alrmininn srd. find that all thaaa prodziota euppreia the eelnbility ef rtHea in veryirg degree. HaaixLus powder is many ***** sore effective in this respect than any cf the oowtpoonda of that vs hove exesdnsd, e.g. or loss ef almainlua pc^ar V " I . _ H- < <v: . - .1 .... an the asbestos oonplrfcely suppresses the'salability of-the silica, "whereas the same effoat is only cbaarrai. with "the better typos of alpaina,' wtaai'l^i Iff1 ";c proa out. Consequently, we believe that if any of tfc fihranirr rwrultias "iC W`I froa the praaanoti of gaall particles of asbestos la tin Imags is dee to the oWr-r^i effect cf silica la sciatica, -then traces-of aluminiua rill ba* scare affetetiv* in prceentlat 'this than traces ef ilnala-ti.-JC Dr.- 'King j-a' hojrfpy-fen ayrmi-nm ---" this point acre fully la aalaal aacparisaenta-in tha -Bar fiitturs. V-v*' ....... . ; . .. :'C--u.-V .J-.. -zz rx ;.x~ 70 "'3' ..x j ea ia agreeaeixt1 with Sr*/ttsritcsr "iirlils suggestion tiiat'tha' '' er faraatienof asbeartoaia bodies appears yo ho ca attcspt oa the`part of'tbs' lung ts ci to overseas ihs; irritating mehaslcal effects^ of the'riisaral : fibre end that shea the fibres bars boear1 coated'sufficiently'ta'Trend than J'rj 1 - off at the ends, irritation my well asase;^ 'Ve hanrs tried, without saocess j to produce asbestos is bodies la Titroead -I'shall bs;tnsr7-interested to obtain :J dstails of a atetbod- fcr do!ng this.- If Dr.' Gardner1 ssocseds'la ebtainiag- - sufficient asbestoais bodies for tests la satasl1 arparicanta I* fod-1' ftrurc tbatfJ ^ the results will be rexy interesting and significant!' - - r-