Document 6RGdOV7m2RVw4Z67OjwBOqQER

i _ I S St. Louis - Qeneral Officii May 27, 1964 Federal ^atardous Substances Labellrm Act Your Nemo of May 21, 1964 r. savia ftfi&YX Prank T. Nemita Los Angeles Under the provisions of the subject set, Aroelor 1232 would be classified as a "toxic substance alnea its oral LDcq in rats is under 5 g/fcg of body weight but more thin 50 ac/kg. Similarly, the lethal dose when applied to tha skin of rabbits is lass than 2 g/kilo but aora. than 200 mg/kilo. The ranges indicated above apply to those products which reach tha market place in such a fashion that they are included under tha Federal act. Z cannot predict what tha lethal doses would ba for a formulation aade up of 25)1 Aroelor 1232 in ainsral oil. it is quite possible that they (tha oral and akin lethal doses) would not -ba four times greater than for Aroelor alone, we have several indications that the Aroelors are aora toxic when in an oil aolutlon than when adaini.stared undiluted to animals. The ultimate responsibility for the proper labeling of a fonulation remains with the customer since we cannot be expected toget animal data on every possible formu* latlon containing a Monsanto product. In all the varying concentrations and with the innumerable combinations of other components such as antioxidants, colorants, etc. The very minimum precautionary statement that 1 think would be necessary would be: "CAUTION -- Harmful if swallowed. Keep out of the reach of children" EPWiaJb Elmer P. Wheeler