Document 6Bo3bybemR1mdBvo7BDp9rDb1
September 24,2003
-B- y t-land Delivery
Document Processing ,Center (7407) Office of Pollution, Prevention and Toxics U.S. Environmental Protection Agency -i 200 Pennsylvania Avenue, N. W. Washington, DC 20460 Attention: Section 8(e) Coordinator
' Re: TSCA Section 8(e) Submissions
Dear Si:/Madam:
3M Company ("3M") requests that EPA place the attached studies in the TSCA Section 8(e) docket. We have included a master index for these studies
identifying the study title, test substance and CAS number. A Confidential Business Information (C61) version of this index and the studies also is being submitted today pursuant to EPA procedures. 3M has not provided C6I substantiation with this submission, but would be willing to do so at the Agency's request.
3M has concluded that data in these studies may not be, strictly speaking, "corroborative" of previously reported or published information as defined in EPA's rep.orting guidance or otherwise potentially may warrant 8(e) submission based on EPA's reporting guidance.
undersigned submission.
3M appreciates EPA's attention to this matter. Please contact the if you have any questions or require further information regarding this
Very truly yours,
014 Ml/iv,f.
Pd.
(q.oy
Dr. Katherine E. Reed, Ph.D Staff Vice President Environmental Technology and Services (651) 778-4331 kereed@mmm.com
Safety
TSCA
. EN-VIIRONMENTAL PROTECTION AGENCY CONUDENTML BUSI~SS NFORMATION CENTER
- -- 1200 PEi'GdSYLVANIA AVE WASHINGTON, DC 20460
Date & Time Stamp:
.
Currier Receiaq
, I
Compnny Name:
, . I -
No. of Dwuments:-
4
September p ha---
r>qcii
26,2005
Revision
to 121 Studies provided in Master Index to Studies Submitted Under TSCA 8(e) by 3Ni Comrjany .. (Cbnfidentizl Business !nformatih Redacted)
Updated from My 15.2&X spreadsh.4
on September
24,2004
15671
15672 15673 1567.4 i 5675
: : `. `. : 15676
PdmaryE~InitatinStudy-
Rabbits
Guinea 5%~Contact oermat Inilatio~~niltimb'on'
tim-a-t.y_ Fzp. Irritation study- Rabbi
AQne OmlToxtity Screen Him T-2712CoC h ~bhw ~atmts PrimQ'Sdn !nitaSon Test wiu, T:Z725Ec(R@eat A&iikm) In Aibno RsbbW
ARdaidti?bt:~!kd=ar trd. tation iest titb T-i2.725Ec'h Atbino . .
CHLORIDE/f3lSPHENOLAF
in triithyleneglycol
?O% solids, (Ethomeen $112 l.OM with diettifl'sulfate
0.94M): 80% water [Ethoineen S/12 = R-
`N(Et)+(CZH40H)2..wbere
ff=C18 with 1-2 double
b&r&]
fB&noic gcid. hepl&uoro-, calcium salt
perfiuorohexanoic
&id
II
:
YPiopeooic.acid,
.(;ui,h
:;
2methyl; octadedyl ester, polymer
.:
:.
P-95-290 - No CAS number
commercial
20% (61791-24-O 2366-98-5
307-24,
with &l-67-5):80%
7732-18-5
commercial lR&D
II
11..
`,
7677~36-2
`.
57589852
.'
.. :
;,
._
.-
._
. .
.-
..'
-..
: ._
commercial ::..
cbmni&iat
none'
t
I
none
{none
I
`.
."
:
none..
. .
,.
done'. ._
3&67589-95~2;
5%.66541'61-5
; 5"/0 6854~Oi6;
5
5856~G-7; 5% 68815-72-5
commerciaf
none
I
V.o CAS#,forsalt-put
itis the salt of [t3326i-O7-7J[li~
l-
t2-21
&nimerciul
:
R&D.
:
I
: _,
. . _' : _. :
ktie Oml Toz@y Scr~nwith T-3448 in Amino 15683 Rats
SS% poly(oxy-i ,2-&hanedii),
alpha-[2-
[~~~[lb.~p~ede.~~uo~~s~~~~~?rni~Jeth~~
o,me&i+ydrp$$.l2%
p@thyle&Kglycoh
7Gvelw;
4;86~:~(0~~1
.+hamd~~~:12! alpha-f2-
[et~~~(p~ni~~~~fluoroheptyl)sulfon~j~mino]eth~~
omegabydrawy-:
4% residual r&an% fluorochamica!:
3% heptade@luoro-i&nesuifonic
acid;.&812
pbty(oxjW1.2-ethanediyf).
aIpb+-
Iethyl[(ondecafiuoropen~)su~~]ami~o]et~~ega-
hydrov-; 0.9% 1,4dioxane; 0.2% n-
ethyfpernuoroocttinesu~arn~~~~
alcohol; 6.03%
linear n-ethyl parfluorooctanesulfonamide
:
R&D I
`. .
i8% 2911?-08-e 12% 25322-68-3: 7k
:.86% 56372-23-7; 4.65% 68298-73-3;
:I-7; 3% 17632bl;
0.81% 68296-W+
: 0.2% 1691 -Ei9-2: 0.93% 4151-59-2
7732-185: 3.24% 68298
0.3% 123-9
1`.`.
I-
commarcial
: :
--_ _
I
1I .
none
hm bficr&dogicRl 15tjlM Company's C&pa&
&(agmicity &sarj of,f3~ 65%diethyiene.giycot
T-3516
urethane: 10% titer;
butyl ether. 25% fluwochemical 1% methylethyl ketone
Acute Dcmt Tox;crt, Study w:Xh T-3451 in Alb'w
15685 Rabbits
C8F17S02N[CH&Na
`5% 112-34-5: 25% 30697%47-7; 10%7732-l `693-3 7968-59-6 ll-Octanesulfonamide. .1.2.2.3;3~4.4:5.5.6,6,7~7,8,8,6-heptadecafluoro-NiAe-th--yl- sodium sa-lt)
8-5: 1% 1
v September 26,2005 Revision to 121 Studies provided in Master index to Studies Submitted Under TSCA 8(e) by 3M Company on Septemk~4, 2004 '
Acute OralToxkity - Method. Summaq. Pamcgcqy.
Primary Demul Irritation - M&cd, Summary;
Primary Eye lnitation - ~#Jiod. Sumniary. Guimza
15686 ti$JMtition-~ethod.summery
[I
I
.
[I
R&D
R&D
.1
..2
. .-l&89
~.:.15690
4-Hour AWe #i&l T-3.82Sbr R&s
M&&ion +x-k&
R&xyfyeIrritditon(ConoslonS~.inRa&~. :..
Study&iU.~
fluorwhemicat
diluted in 1.1.1~tichloroethBne;
kuor+hemical
= 3?%,
~~8H2&17N308S.C27H28P15N308S.C26H28~13N3
Q~S,625H2B~lj~3~8S.C14HtO~`i~N04S:C13H1OF1
5N.D;26% methyt jsobut$ ketor& 26% FREdN
Stoddard sol\lent 3% i&ziridioeca~xamie
cierivati&: 3% methylchloroform
12'hep~~fiuorcbu~ami~cnt.o~.~nit~ph~n~t
_.
..
:
: .. ..
113; 5%
3756' 6t?2&-752;`i6%
1O&1.0-?: 26% 76-i 3-l: 5%
805?41-31.3%
68583-98-2; 3% 71-55-6
@3326019&i
..
1
.. -
:
commercial.
.jcbmti&iaI
:
I
.__
:
non!?
j `.
c&e'
1
:.
`... `_
;2@i?fKFlZN~~8S:C2~~28F~5N~O8S.C26H28Fl3~~
.::
~6~.C'~5H2i~i'rij308S.C~4~~OF.l~NO4S~~l3~~OF~ _ f
5N0;26% m&hyl i&tj&tdite;
26% FREON 113; 5%
:.
'
: `.
._
., . +HQ~K$C&A~XOI knhtiwTaxiciiyS-w&tith. 15691 +382SinR* 9 5692 .&3!3sJipe h-ihaen . To&titrTesl.
Stoddardsot&&3%
`t-+irid@wa@oxemide
3i% 682987&Z?- 26%`108-10-I.
26% 76-13-l; 5%
d&ivatiue; 3% methylchloroform
.'
.....
8052-;113: 3% 65583-98-2; 3% ;S-556
commerctat
~2-meulyt2rprop?te
`_.
.
@z39~2+4
, `.
not cMimenial
in US
L none (none
91% 1;l.Gtrtchbroethane;
[];[I methylal; [] 1,2-
notwmme~iat
ii
:,
15693 T-WI; Ac@tnh&lw . ~PxiciTest
.butytnr? .oGt+ f ]
i 9l%71556;
it; [].to$aL5:
[ 1'1068M; []
not.commer&t
inUS
p.`s' .
`15694 T-Z345Acu&~;~6T~Test
jheptafluorobutjqt
Gloride
f375-16-6
commerciel
none
9+ 7;1,1-trichkvoethane;
2% me. thy.ja,.l; 2% j,2-
. .
.,
.
butyfe@ b`jidef~l% ni$iiyr'&y~
ketone; 1% mdthyi
.
September 26,2005 Revision to 121 Studies provided in Master Index to Studies Submitted Under TSCA 8(e) by 3M Company on September 24, 2004
(Confide&l Business Information Redacted)
.--
L
.J
Updated from Jtiy 15.2005 spreads+%1
I
`C?5% 77-55-6: 5% m&tiii Gf 8837% 7i-S-6. iO%
6655592-O. 0.1-Z% 109~87-5,0.1-2%
106-63-7; CAS#
68555$&p is P-Propenoic acid, 2-metJryC, Z-
[((hepta'decafkrorocctyl)sulfonyi]me!hylamino]ethyi ester. potymer with 2-
[mefhyl[(nonanuorobutyl)sulfon~]amino]e 2-propenoa!e. 2:.
2-methyl-
(meth~[(pen.~decs?uqrohep~~suffonyl2-
methyk2~propenoa~e.
2-
[~ethyJ[flidecaif~oiohexyl)su~onyl]amino]e~yl2-
methyl-2:properioate,:2-
95% ~.l.l~trichlr&?~arie~
5% fluorochemical
[me~~(iun~~fluora~n~s~lfo?ylamino]e~h~
2-
c&e lntlalation roxicii swdy with 7-4129 in lb.9 (flrrqrochemical = 8667% methylchloroform;
IQ%
r!Iethy~2-propqroate
and octadecyl2-ineth$-F
at _' fluorochemicel'polym er) : pmpenoate : .kommemial
,-:: ,'
`_
.:
9$% l.l,l~ti~hl,or.oe~ane;
6% fluorochemical
..
/
._.
(flud~einiil.=`37%
* - ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~_~~~~~~~~~~~~~~
.
`. ' :'
:.
. .
_`.
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
-. .`..'
., .`_
"_.'
' iN.00; 2&`i$efhyl
isodutyl keto~~.~26% FREON 113:
!+.J6 71&6; 6% of:(37Y? 6829~76-2;.26%
Id51 al;
gte I&I&~ ~~~&Studywi.~ T-9730in the'.
a.
`.
_, ,:
:...
tie &al iadci Study in R;its: k& Dkmal
itd&%"dy lORabbits: Acute.Eyel,rW.m
u@ in Rabb?ls
:d k&Mizition kWtz&.nTes.
Shady in%uinea big% -
5% &ci&d~&en~
3% I-&!indine~&xxar&dle
derivative; 3% me~hylctikxofor+
. .
,:
-.
Polyoxye~hyfe~
@amine
biilmeib~mpyl'ptio$phonium
APcorilptex
,.
PertWro&y!
Sulfonate
chloridel3isphenol
*
._
: 26% ?6-13-l; 5% kO52-4i-3;,3%
68583-98-2; 3% 71-
-
~55-6) :.. .....
1 _' --
~mmhial .,
: PMNt P-96-1262 - &AS 306?74&-8
- PMN name fully ,.
dis`dbsed on'SNlJR
. .
t
._ commercial
PMN# P-9529ti-`No
CAS number
:,
:
`. commercial'
ti&iwTefest on T- 4413 (`1 inthaL5178YTKi~ [1;54.9%+fat~
[ ] polyethyleieglycd
"
+.L~@~+F~i@MGtatiot;As~~,$v~
sp~~nrriqnodeat~-~~~]?.6-dimethyI-?.sdioxa~ol
._
:
lpacaUC~,:
.acetate..
.I__
[I: [I; 548% 7732-19-s;.~]`9uO&k&;
[J; i] 628-00-2 `e&&ne&t
~~&t@latim Tw iv
.St$y with T-4354 in tfae
,78.3%w&[] tribut)ilme!hoxyprbpyl
; `. phosphor&m
:' chlorid&isphenol
, +&o/,n32elss;[;. `,
.' -c. .:
`.
,
. . c`.ommercra.l`..
".
maw Dermril IrittatjMtiion
Study in p8bbi.B RF comptex
P-9rXBQ- &!o CAS number
. .
ci;itne~ial
.,. . ..
.
95-99% l.l.l-trichloroethane:
O-3% dimethozqmethane;
`&22x f-butyl a&hol:`&`l%
1;2-btit$&ne oxide' o&1.5%
`.
__
..
._
`._
:
__
`,
tie~t,.rn~&a~7q~6vs+-ti
& Ratih+ : huq*al
sijri~~-?iii~~~~i
Z& -tie@ &q _ stFsa% ii&a:
a& 109-87-q 0:2% +.-6501 O-I% :
t'
mary Eye InitahbrrlComsion bbits
_
ketone... ..I
..
:
Study of T-5261 in lithium tetraRuoroethansl.2-di&fcnimide
+173,%-lsopar
G;.1:5Syh heptane': 0.7%
10638-7: Unknown
0.51.5%
68298-78-2:
O-1.5% I&-10-l
commercial R&t,
sulfonemidaa. Cdsalkane.
perfiuoro. N-(hydroxyeihyJ)-
9Q?73% 64742-48-9: !.596% 142-62-5; 0.7%.9108'1-
iade Inhalation T&idty Evaluation on T-5231 in
15727 Rat b
I?-methyl. reaction pmducts v&h epichlorohydrin;
99-l =-C4-8-alkane. perfluoro.
adipates (esters); micellaneous components (each less mefhyf. reaction products tih
thani%j
, (esters).
N+hydroxyethyij-Nepichlorohydrin.
adipates
commercial
4-H (our. Acute Inhalation Toxicity tidy v&k T-5305
15728 In Fzals
I
II
Cl ._
not commercial in US
Il- 4-H Iour, Acute Inhalatica Toxicity Stu6y {Limit Test)
I5729 wilt 173343.1 ir Rats . . . 4-H w, A&e tnh?MowTe&%y
Stidy Wth T-5308
15730 iriF :SS
-.._.~-L
11 57% heptane: 25% fluorochemical
hydrocarbon
~-HOW, AC& Inha~ion Toxicity Siudy (1 imit ~~~~~ polyacrylate copblymer. 18% ethyi acetate:
15731 UVI T-5357.1
miscellaneous components (each less than 1%)
II
[I
I57% 142-82-5:
25% 68555-92-O;
18% 141-78-F
not commerciat.in US
not commercial I
sbmmemial
in US
-. .
n&e
_' . . :
.. ,. :.
none :
. norie
.
none
`_
TraileSewe~ m'mie
: j Ttidi?,Secret ~mi&rre
. . -: none
. .
`.
:
..
i-tone
`. none
none noicommercial us.. not commercial U.S. riot commercial U.S. t
/none
.'
:
in in in
I
`W
(.
,'
September X,2005
Revision
to 121 Studies
provided in Master Index to Studies Submitted Under TSCA 8(e) by 3M Company
..(Confidentiaf. Business information Redacted)
Updaled from July.15.2CUS spreadsheel
on September
24,2004
15732 Acute DermslToticity Study of T-4201 in Rabbits Lithium Bis(Trifluoro.methanesulfooyl)imide
S+Acule Z&Day Oral Toxicity wiu, T-2616 by O>ily Sulfonamides.
CCBalkane,
peifluom, N-[3-
f+q+ in the RX FOIIOWI by B +i nay necovery (drmethylamino)propy13.
IBactiun pmducts With acrylic
15733 Period
acid
; s"&vts a&osr Ors, -c-..:--t._ ..:a. 7 .%n.,. L.. n-x. Sulfonamides.
C4-8-atkane. oerttuom. N-B-
G.&q in I& Rat Follt
r.
xi734 Pwioa
-. a&
_'
1. 1.Aade lnhslation
.' i57351ng
:
.:
Totilr _ Evaluation
on T-5187 in
`194.828 i:l.l~trichlo&hane:.1.59%
I!.?24% ~t&nol;
0.469% fl&&hemical
polyacrylate bopctymer; miscellaneous
I(&& less than 1%) 1
fSulfonamdes,
W-8 alkane; pertIuoro,
dimethcWmetha.ne:] hyd{ocarbon
components
N-methyl-N-@-
157361T-42.p4-Week
Oral
. I` . `:
Deal Sensi+ion
&i$-M&pmbetion'Tes!
I-
...
Toxicity Study In Rats
.._ S&&y of T-5173 is GuIdea
lo&de&2.ox&-exazefidinyt)n&hyl]
,.. .* .
._
. .
6O%~watw,.[ 1: &:ethyien.e
. . .`, gtycol. i]: 1.5% unkn&n;
: p&&&lene
mon40c~~~erijrl:ktl;er;lx
ac≠;[:]
I AL r;OL khn~r U. AP ~7% "m..v,~lf: Q&J, mmm@,,,,,.,
lluomoctatie
:'
90076-65-6
P-W-1 83 - NO CAW
IP-80-183 - No CAS#
I 94.828 71-55-6 IO:469 68555-92-O
1.
"
IP-90-dll:cAS# . .
: 1.59% 109-i-M; 138704-559
[.I 60% 7732-18-5; f.]: 6%.
67+6+:?;]]
. .. .:.,
.`. :.
48.5%' 647.+24&Q, ii:&
107-2t-I; t &&;
commercial
1,2 24% 75850:
commercial
I-]commercial
I I t commemiat
.zommercial'
[ 1: f ] 903Sl,Q-$ :'
I& ~eommemial
..'
3% tiMi P-92" ., `.
:,_ ::,
.. :
none
none
lnorie
I
I'
`. I
I
I :
I
n&e
.. `.
: T&b._. Se-.C_r@`J ,. Trade. Name
T-&&&de Se&r`e. t ' I ., ,. . . -
_.,.`."
.: `.
`,
. .
:
`_
"
A&e Infialah ToMtj Ev@&ion on S-5746.&
: __.,, . .: . .
t.57& R&
.: " QQ:Q& naphthct sptritq I]'
I
.:I:. `.`.
I
! -i&i6 ~ti~:wa&To~~:Slud~ofT-5~24
inRae
96% IsOpar 6: i.6%&eptane:
f Awte Inhala& `hkiW Study ofT-5725 fR&
.:
,:
[ ]
..I,
~jS9.92%64741-65-7; -.
. .
196% 6i74i-489;
.'
~96"/i3474165-7;
;.
_:..
I']
1.6% .142-825; [L
3.6% 142-62-5; f ]
.. .' ]:
]cemmerctal
I
: "
1`Af&nfxcial
I- .'
,
-_ _'
."
:
d'
: :
15750 15773
... -
. .
R&S
s~.+-&~ intravenc& .T-5963 :n Rabbits I
~&mM~~kin~ti~ my
93.2% water; 2.6% l-(2-butoxypropoxy)-2-propanol:
of 5-CN-metwwfl
ubi-uuctanesulfonamido)methyl-3-
octadecyt2-o~~l~~iilhone
/43.7Wvater.30%
animdnium
6is[ethyl(perRudiooctane)sulfonayllphosphate:
20%
isopmpyf$@ek
G%`Ntethyt heptadecaftuoro-N[Z-
siin~,~~
tntrBYenWS P~~EMI~~~~MJ~ Sludy of' tphosPhonodxWhy[J
salt: 0:3% toluene
:
"
octinesutfonamide
diammoinum .
..: ., ,_, .
-.
:___. .,. ..y
,, ._ . .,..- :.. . 1 .. ...
.
-I] 96.1%.7732,i&5 PMN#-P-90-11!
; 2.8% 29911-28-2; - CAS.306974~19-6
discl6sed on SNVR
I-.
43.7%. 7732-l 8-5; 30% 30381-95?; 6796S-641: 0.3% 10%8%3
,- .,
;. ,. ~.
_
[ ] - PMN`name
commercial
commercial
.`I
..
20% 67-63-O; 6% : commercial
: .. .; ..:_--...
:
.Ifrade,?-ret
1
]rfriiure
&a& Secret
m.&re
.. _.
Trade Name
I
I
Trade Secret rradeName
.
.Y
*
I
*
September 26,2005 Revision to 121 Studies provided in Master index to Studies Submitted Under TSCA 8(e) by 3M Company on September 24,2004
(Ctinfic&ntiaP&.kiness lnformatio'n Redacted)
.*
Updated fmn July 15, X'35s~eadshsct
87 95% Ruorinated aiicyi aiitoxyiaies; 4-t%& Bnear X- '
I
I
I
,Iethyl- perflu&ooctanesulfonamide: ethanedi~),.alphB.-(
2-4% poly(o~l.Z-
I
I
I
I'
[~thj~[(pentadecafluoroheptyl)sull0nylla-
87-93% 68958-61-2: 4-10% 4151-50-2; 2-4% 6895
.omega.-methoxy-:
04% residya! organic
1; O-2% 3150632-83 0.1-l% 68957-62-O; Residual
I fi&&&~icals:
O-2% c8 stilfonamide: 0.34% l-
:. Oigahic Fluoioch~micals
tiay consist of one & mo
!he&ne&lfonamide.
N-e:hyI:
t@ followin,g GAS numbe,+Z 279%393.2444~09~7.
i,i,2.2;3,3,4,4.5.5.6.6.7,7.ipentadeBnuo~:
I&-99-2;
87988-71-4.31506-32-8.4151-$0-2.8798
miscellaneous.components
(each.less than 1%)
Bi2,`213181-794.213181-78-3
and754-91-6.
cbmmercial
54.97% water; 11; 8% methyl isobutyi ketone; 5.5%
&:.h .,y' e:tie.&col;
tttaq 1%)
mistillanepus
,zomponents (each less 3-.3.^y_^,_ya-f-^,&+,t5~^-5- ; .Ij;.a. %..A.,,"-~r..-i`"--l,.. 1_ r3.3k,% -I,.V- I-L,..I-I* ~;"_"_"_"^"_V^ `"L'di^f,
t-a$e&lie trhvenausPharmaccJ~~8ltiy.bf
62% wteer; 30%.fluorachemical.acryiat~;
7%
62%2732-18-5;30%
6858614-1;.7%
253&X8-3;
1%
-. TretleS~t
-"
`; 157ti t&&~~k~bbiis'.
`.
: . polyethyteri~glycol:
`1% ethyl acetate'
.'
:. 141-78;8
.__
.. . commercial:
. . 1.
f@cljiNti.
:
:
,. .. .'
sim bm~~av~ it5778 T-m;n'Rabb&
PbsrmacijlrjneticSbf . .
6~.wa:dr;-[.],inisceilaneous than 1%)
timponetits
(each less
: 60%`7732-lBJ;.[l
.. .. .
.: ." commerciat
m3d6 tc&SCret
: . . . r&We
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._
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' ; : `.
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:
1
. ..
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:
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2-pr&atiol; 0.?5% .I-methoxy-2-pkpanol;
f&lSri%
86%:7732;1815:
7% 752&-5: 2.8% i91 1-28+2~ 0:75%
. .,
il577i &klnf&~TUi~ .,..,
Study of T-623Z.in R+' unk?town; 0.66% ethanolamine;
0.0012 ace& &id
+-J%S&2; b.OS% .141-43:5: O:OOi% 84-19-7 : [ 1
. .
commerciai
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`+++ oermal.&ma&em.sudy 1578d &Rabbits
of>m2
:
`.
do&?$&izenesil~o~at~
5:4'V? i]:as.ssY%water:
0,009%.1,2-di~rr;mo-2;4aic~nobutane
. .
19.4% poiymethacrylate;
15.5% sqdium
DemulsEflsiii?nsi~y I~$`81 Pii M&ikZiti&Tesf(EC
04 ~~02.i.n G&e?4 Guidelines)
dqdeci/lb~~~~nesulfon~te:,
5.4% i]:69:691%.~~er;
0.009% P;2dibromo-2.4~dicyanobutane
AC+& Eye WtitatioNCom6sim ShdywithW318~h.
15782theRath'
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15783 in- . R&.L.W+larr .,. Se_n.v.K_lcckrshreI. #+&.&.k.m. ) ..__ R_.u..o,r.o._ch..e.,mical ;_. tiydic&rbon -.. p-o.lyac-r.ylate,. -.;. copo. lymer.-_
._ &&&o,+~c~~p~~
Tafein. l-Bt+n-tjlfiniC.acid.
1.1.2~?,3,~:4.4.4-nonaRuoro-.
9:4i 25087&7;
.1.5.59/o 25155-30-O;
5&s; 0:009% 35691-65-7 [] `.
$9.691 F 7 732732-
t..*^-^*:-,A
-
. .
!; not commerci:
i
-fis+sp-el
,miMure ._ ..
:t---Be,.&*
6 ; 2&80%.methjr! nonafluo~ois.ob.&yl
ether; 20-8b% ðyl
~ $57;88 ~t~he~~R~a~t~I(~tn~b~al'atkm~&niniskaM)
1..*_""".
; .; .
Triphenyi Sulfonium Chlohde / Hexaluorobisphenol
A
Complex = 21~2% BF6.1n~vanous forms;.Z4% Str@ure
I: 1.1% Structure II: 10.1% $tructure Iit 518% unknown;
.4p.p% ethyl alcohol: 11.8% methyl alcohot 4.3%
$339 Eicterial Rev.er= MuMan Ten of T-95
Isoprc+yl ?l~h~l
_': l,~ZbO 5(c-LtjFja.$i~lMw&?t.io.)r.ToxicityinJ?ats o`.f P&flucrc+i@W~~ p&tluorccyclohexene : .
.s~e~ty DOSB Darmst Absorptionfrdxicity Study of T-
_ `$5791 6502andi&O3in'Rahbiii-.
- -.
f]
pnm~ry Eye IwMkwiConosion Study 01T6766 in
15792 Rabbits.
Lithium Bis(per~uoroelhylsutronyl)imide
~;mary ~emnal InitatioMYxroion Study of T--68.04
15793 in Rnhbii
Lithium Bis(peffluoroethylsuifonyf)imide
1579415DayInhala(ionTaxicibScreen~HFE~l
/c-C-6-FllOCH3
~
,637,,:.2,,
66%
43.3% 64-17-5: 1290
11.8% 67-58-I;
35~7%9
PMN# P-97-226 - No CAS#
13284344-8
i32843-44-8 4943-O&2
i63_702-07-6 9.3% 67-63-o;
:. P-9?
-
, &mmercial _ _ i
ycommeruac R&D itar> commkrcial commercial commerccai
none
:
I
Inone
I
noffe
R&D
I-One
none jn0ne
. : .;
,.. ,
. .
.:
._
.
- :'
:_
.
September 26, 2005 Revision to 121 Studies provided in Master icdex to Studies Submitted Under TSCA 8(e) by 3M Comoanv on Se&ember 24. 2004
&8nfidential B.c.siness Information Redacted)
r iPriin21~ t3e In ~UdnCorrosion 15795 R~bbn(0tXC Guidetines)
Study olT-6804 m al Lithium Bis(pemuor~:hyrsulfonyl)imide
Acute Oral Toxiciiy study 0fF68M In Rats (OECD
Updated
from July 15.2005 SpreadSheN
I 13264544-8
15796 Guidelines)
Lithium Ris(p~~uoroethylsulfony0im~~e
1'32843-44-6
58.5% water;[ 1: (1; 1.5% sodium di(Z-ethylhexyl)
.' -
commercial commercial
sulfos~~ciinste;O.pl~~
polyethylene glyccl so&an
Dmnal Sendimion &dy of T-6906 In Guinea 15797 Pigs. M.w.imizatiipnTest (EC GuidetInes)
Eye tnir~tiorxonorion Study of T-4127
15798 t@bti
c
si~ge-oose lnuavenaus Phalmacokinettc
15799 TasZp in fiabbf+s
Oermal Sensitii6tbn Sludy of T-6924 in
158~~~Gw,f~(Ec:G~aliri~s):
`,' O~frW'S~stiiion
Sludy of T:7@3S b
`15mf pig~~#~~~j~i~,c,~~~~~),-:
In the audy
Guinea Guinea
,'
nionoote&e;`O.27% alcohof: 0.10% Triphenylbt'nQf ComplGx 0, II
[I ..
_I ., i-1 ,. .:, 1
ethylene dimethoxane Phosphoniuin
' __: `:
glycol; 0.13% ethyl /c8 Sulfonamide
: ' '
56.5% 7732-18-5: 6: 0.27% 107:21-1;
(1; 1.5%
0.13%
577-11-7; 0.81% 900&6-65M-17-5: 0.10% 828-00-Z
, commercial
P-86-141 II II
-NoCAS#
..
. .
cnmme&iaf
R&D I j:R&b :. .:' &d `.
none none
Trade Secret mixture
none _.,. .d&D
R80
"
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'
R&t of Sera and U& bata for Wf
Npthyi hepfad.ecafluoro-f@2-(phosphoimz+hyf]
15802
:: . I.5863 ,'
Mbn'~~le~l.~~"aryAOMES~ii! . ..__ ,, .-. ::..
wijw Di.s~~~+,pc&&tis
<$@dy tij6.:$704$f; ~ti&;. '_
Rat@
S,@y itl Rati ;I. .
~~~olf~namide'~~~,mrrionium
$&.. ,__ ., ,-
. . 67&j&69-1
._ awndnium
`. .. ..
:biS[ethvl(pen"sr4oCtane)fblfo~a~~p~o~ph~.'~~': &&$98-7
55~;&Wyelhy~nq
gtycol disteara~e; 27.5,%g@eroi
.. .
:
I..
" :: : ;
: . .,' .
,:"
.:. ., . .
.mowste&.t&~15%hexane;
l,6@is~ariSt&;
; hpm@n@rner, N-(hydro+thyf)-Nmethyi
p&luom
-
`.
Cd-8 SS%`gdOS08.7;
.' 27.5% ~1;$6-31~1~
' s&nob Qose In&aa;erla. Pf&ila&~~
.. iz!%it32 &ii!T:7@2 ih &bjts. I'
.
FCsdZ.Monosster-peticwin
6wy Rals
alkaWsulfo~amid&and
stearyi @chohol
`katbnicfa'kty derivative. _'
-N&&j4 h&ptade&tluoro-N[2-(phosphonoow)&hylj
blocked;
25%. (dAS 30&76-6%)
68039-12'3
:
`.
name $+&on _.
i5805 WJ& ti.T+3774
: i _.
DetcrmlnationofI?FOS.Pf~snceand
~a~+nt$&~h&wr&m'ff~Detmar~&pt&
Shrdies.ofT-7X8 +d T-7107 kt Htx(NiwjSPF
kfanpsulfonainide `_ .;
diammoniom,s&
..
:.
_:'
679&6i~l~
I- 15806 Rati r
9$25%polypropylene;
I ;
:
.
-
98.25% 9oma7-0:
[I
:.
`.
,. ;
75% P-99-188 SNEER; 2.5%
.: 1
: .:
_`...
dommercial
. ..
:_
;hrnem~,
. .
i.
`.
... ..'
: `.
`_
commercial .
commtii ,..
:R&g
: :
._
ione
;.,
.( .. . ..
: .: :
none
_..'
:
: .. :
T&e S&ret -, :
T&de `&me `. _.:
`. nbn&,
`&$a
. .
1
L
c
1 s .
.
. .
,.
. .
c `.
2,l-f$han~~&i)]l&
16% ffuor&liiphatic
ammdnlum
7580% 3/)38!-9&7;10-iSs/67369-89-1;57%1691-
.,
`. Twe'nty-eieh: Day Repeated Dose Oral T&icjty
15824 Shrdy of rl-7005 io Rat8
coprod&; c&mdW
OS+%
fluorbaliphatic
di~mm&ium
- 99-Z; 15% 2250.98% 67939-9M ..
l-5% 67939-97-3
051.5%
&ommercfaf
A~ut~.(W,iwr) inh~lation.Taxicity of Test
,;
.:
Atmospheres Obtained after Heatin9 f' j or 15825 rtaypbpy~eneh.~ets
Toxicqkinck Study ot
F?tty acids, Cl&unsaturated-dimers,
Z-
fmethyi[(pe~uo~~C4~alk~)~f~~~~~]e~hy~
P-36-3625 esters SNUR
CAS 306974-6310 - Name'disclosed
on commer&tl
Pertlurooctenesunonamidoacet?~
@.f555: T-7071.2)
15826in Ret%
perffuorooctaneduffonamido
&boxyiic acid
2806-24-8
Rim
?
Final
6
44.
.-
. .
::
. .
September26, 2005 Revision to 121 Studies provided in Master Index to Studies Submitted Under TSCA 8(e) bv 3M Company on September 24, 2004
Updated from July 15. MO5 spreadsheet
'' '
I
0.007% aliphatii hydrocarbons:
(1: 0.85% l-m&ox+
pfOpafld; 2.58%. l-(2-btrto~~opoxy)-Z-propanol;
0.84%
ethyl alcqhol; 7% isobutane; &.54% water; 0.009%
methyl i$obutyf ket&e; 0.186% iio@Mlind;
O.K?S$:
I `0.65%
107-93-Z;
2.58% 29311-23-q
`0.54% 64.17-5;
arr'iinonium ii@nx&
O.O&% ethyl'a&te:.O.O09%
7% 75L2&5; 85.54% 7732-.iS-$O.O09%
loilo-1;
dw!e Nose-Cdy lnhalafjon Toti,y.Study~f T- hep$ne; 0.017%.2-methoxy-l-propaool:
0.018%
O.l66%iiO-91-8:
0.038% 1336-21'~; 0.046% 141-78.
7OS7, TriW. T-7069 and T-i'& in pats (Limit . . . . I -518)27 req.
%k Ocular k&lion St&y of T-748SApplied lo
solvent naphtha me-.thy.l-_ alcohol;
(petroleum), light aiiphatic; 0.1 Sk% sodium niti&
0.032%
6; 0.009.76 14Z82-5: 0.017% 1589475;
O.iXS% 6474
89-8: 0.032% 67-56-l: 0.184% 7631-99-4: (J
15828 h'ew zeetand White RebbiIS .,
`, T?*QneticS~
Of Pemwmoctane
Sulfonamide
pot&urn ::
nonafluorob&neq&3nate
29420-493
i5829 (PFOsn:T:7itiZ)2)hR&
"
perffuoticctan~~lfon&de
75&91dj.
.,
. ..
. .
. .
Pe~~r~iyqesulfo~$
@@ride (96-S.+.) Anb
.
.
15830 A$ Four+l&n~al~~.on S.tq$y,in.RaD .:%,
;P~mu~o~ur~or~:(2~%).~..
9608% 37&72+ 34% 4200064:O
`I..
Primary Eye Inilatic&qrr&~Study
of T-75082 id
tmmercial iminerciai i&i; Mock ro;:":`-
io'..
_' ,.`.
-
T I rade Secret. m ixture
"C ,"f2 ..
nc im
Iii me . . RJ iD
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-;. ...
: :`- : .i .. : inmercial.'
. .
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not cornme& not commerci&
n&ercfal
..
no :.
.. l-r iri
& 7e
tideSe&tId&Name
. 1 1
`. .
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: *
95oA 1691-90-2: 5% 68555-73-7
307-35-7
15840 MaleCDRats
aCGFll-CF2-QCH3
`.
lt3iZl4-67-5
.
AC& Twitily Screen O, PerRuorocyclohexe,,,? (i-. 70% CfUCk? perfluomcyclohexene:
30%
15841 6878) In Rats.
perf@oroin$iicyclopentene
70% 35.5-75-9
benzoic add 2,3,4;s~trachlor~~((((3-
_. -. . _
- -.. - 57563-052
buildirig block
cbmmercial R&D
R&D
.
.,commercial
___-.-
non . . RO"'
Itoil
no?
Trac@Secret I_-.-Trade Name
.
.
`-p
..-
September 26,2005 Revision to 121 Studies provided in Master i.ndex to Studies Submitted Under TSCA 8(e) by 3M Company on September 24, 2004
,
(Confider-G& Business Infotim&ion Redacted)
Updatedfiom July 15.2C05sWadsheet
_-
15843 Ihe R8t (Acute Toxic Class hlehodl
P&ftuorobutytsulfonamide
68298-12-4
R&D
tlOll8
80-90% Sulfonamides, C4-9alkane. peffluoro. N-[3-
&bchronicS&Day Oral Todcity Study tim T-7320 By O&y Gavage in the Rat Followed by a X-Day
(diiiiethyi&ideamino)propyrj:
tii20% sulfonamides.
6alkane. pemuoro; N-(3-(dimethyloxidoamino)propyl),
15644 RecoveryPeriod
potassium salts
`.
C480-9&
i79005-07-3;
lo-20% 179005-06-2
commercial.
'
none
64% I-octanesulfonic.acid.
1~11s2121'31314141'515.,.6*6,*71788&heptadecafluoro-,
ssium 4% notassium
`.
.
.'
!:4% potassium
. .
: 2%r?ofassiu~
6&oYii/ba.j;s2. 795-3.$&3.2.5y.T5%3872-25-,3871-996; 4% 29420-49-3; 4%
..
`..
m
* 0
commercial
nbne..
Y5846tiati
ppz pay tribal* mpty *dy Of G-401
Me,&ht&de. ~73, and HCFC225cb in Male CD'
15646 k&rs.'
Frve Day Inhalation Toxir@St@y of .x401
_-._ monoihldriife, o-701, and tiCFCZ&b 6 :
in Mak C.6
icokinelh Screen 01 FC Methyl C&amide
fl-
C4F9-OCH2Gi
c-&F1 l-CF2-O-&t3
1.
CF2CICFZCHCIF
`.
.:
.
: --
Low Level Oral Pwrluomoctanasulronale (PFO3) nMIanuoroDuraOesuironronale;
oose To~&a)Ki~ sta in ~a% +-urn amf vrrer peinukheWnest?lfonate:
15848 I'FOS
._
pflllOP3pen tanesulfanata:
2%.potassium 0.5% unknown
&,-,
`.._..,
:_' . R&D :
2h5367-426
;81214%7-5 `.
A r.. 1
(n-isomer) and 221617-86-3 `_
(l-isomer) "
R&D .. .
R&D ._
:
.- 84% 279%39-3:.5.5%
3.87149%:
6027M5-512%
3872-25-t
4% ZQ420-493:
4% commercial
rwne
imne
._
`,_.
hone .
none .
*;.
IW
.
-11.4
.a\#..#
Y. ",.`..a
3JW
WJbl~i
St. Paul, MN 55144-1000
6.51 733 1110
October 26,2004
By Hand Delivery
Document Processing Center (7407) Office of Pollution, Prevention and Toxics U.S. Environmental Protection Agency 1200 Pennsylvania Avenue, N. W. Washington, DC 20460 Attention: Section 8(e) Coordinator
."--+
_:_.-
;-".,.i
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.`-...-'
._;
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Re: TSCA Section 8(e) Submissions
Dear Sir/Madam:
3M Company ("3M") requests that EPA place the attached studies in the TSCA Section 8(e) docket. We have included a master index for these studies identifying the study title, test substance and CAS number. A Confidential Business Information (CBI) version of this index and the studies also is being submitted today
pursuant to EPA'procedures. 3M has not provided CBI substantiation with this submission, but would be willing to do so at the Agency's request.
3M has concluded that data in these studies may not be, strictly speaking,
"corroborative" of previously reported or published information as defined in EPA's reporting guidance or otherwise potentially may warrant 8(e) submission based on EPA's reporting guidance.
3M appreciates EPA's attention to this matter. Please ,contact the undersigned if you have any questions or require further infarmation regarding this submission.
Very truly yours,
Dr. Katherine E. Reed, Ph.D
'
Staff Vice President
.Environmental Technology and Safety
Services
(651) 778-4331
kereed@mmm.com
October IO, 2005 2nd Revision
to Master Index to Studies Submitted Under
(Confidential Business hformation
1 st Revision - March Il.2005
TSCA 8(e) by 3M Company
Redacted)
on October
26. 2004
5859P
ja6OA j861A j862A i863A i664A i-6-6--5A i924A ,925.A tego? Category
THIS
Substance lnformetio"
CAS tnfot-mall~n
CMdantiaMy Svbstantiation'
quatic Toxfcity lagm
ultigenerabon
Data Sheet 48hr Dapbnia
Daphnid Life CycJe Tes)
l+dk~xane: heptadecafluoro-l-octanesulfonic
acid. linear n-ethyl
perfluomoctanesulfonamide;
n-elhylpe~uor~danesulfonamidoe~hyl
alcohol; poly(oxy-1,2&banediyl).
.alpha -[2-
~ethyl[(hepladecafluoroMtyl)sul(onyl)amino]eth~~J-.om~a
-hydrov.
poly(oxy-1.2-clhan~yi).
.aipha.+E
~eMyl[(nonafluorobu~l)sunMlyl)amino]elh~]-.omega
poly(oxy-1.2-ethanediyl).
.alpha +2-
~et~l[(pentadecafluomhep~)sulfwryl)ami"o]et~l~
poly(ory-1.2athanediyt).
.alpha.+2-
-hydroxy-. omega.-hydroxy-:
~eth~~(lcidecaRuomhe~)~lfonyl)amino]e~~.omega.-hydro~-~
poly(oxy-1.2-ethaned,
.alpha.-l2-
~eulyl~(u"d~~uorcpenly))sultonyl]ami~]ethyl~.o~~.-hydro~-:
polyethylene gtycot: waler
I1.4-dloxane; heptadecanuo~l-odanearlfonicadd.
linear wethyl
per6uorooctanewlfonamide.
n-ethylpe~uo~anesulfo"amidDethyl
alcohol: poly(o~-1.2.sthanedly)).
.alpha.-[2-
~ethyl~~epIadeea~uom~l)~~]amino]e~l~.om~a
-hydmxy-,
poty(oxy-1.2-ethanediyl).
.alpha +2-
~eul~(nonanwmbulyl)~if~y~~a~w~emyl~.o~ega
-hydroxy-:
p0ly(oxy-l.2~lhanediyl).
.alpha.-(b
let~~(pentadecaflwro~~)sUlfonytfama
-hydroxy-;
poiy(oxy-1.2-elhanediyf).
.alpheiji-
[ethvl[(lridecafluomhexyl)sulfonyl]amino).omega
-hydroxy-;
poly&my-1.2-ethanediyq.
.alpha;f2-
lethylj(undecaAuoropenlyr)Julfonyl)ami~~t~l~.omega
-hydfoxy-:
pdyemylene glywl: water
quatic fnvedebfate )24-l
~uatic Invertebrate aterlal (LR-8052)
Scratch Remover
Teding - Alkylbns
I LR Alkyllins`
dibutyttin lawate and dibutyllin-dl(2
ethylhexoate)
Testing - Decosheen (Fathead Mmnowt
tDecosheen Ribbon Materials and pigments- Decosheen Blue in
Green Ceres Blue Al: Decosheen Gold Paste Pigment: Decosheen Royal Blue. Solve"! Blue 155.65% Water. 20-30% Stoddard Solvent: 1.5% Sodium Sitkate: l5% Potassium Hydroxide: 0 l-3% Nonytphenoxypoly(oxyelhyl@"e)eRanol
1 ,Cdioxane (123-91-l); heptadecanuoro-1.odanesutlonic
acid (1763-2s
1). bnearn-ethyl pertluwooclanesdfonamida
(4151-552); n-
ethylpeffloorocctanesllwamid~~~
alcohol (1691-99-2). poly(oay-1.2-
elhanediyl). .atpha -[2~ethyl~(hepladecaftuor~~~)sulfonyl)ami~]ethyl~
.omega.-hydroxy- (29117-08-6); po!y(oxy-1.2-ethaned$t),
.alpha.-[2-
le~ull(ronaRuorobuts~fo~]emino)eulv
omega hydroxy- (68298-79
3); poty(oky-l.ðanediyl).
.alpha -[2-
[e~yl[((pentadecanuep~)~jamino~m~~.omega.~y~o~-
(68298-81-7): poly(oxy-1.2~&an&iii).
.alpha.-12-
lelh~[[tridwaRuoro~)~I~yl~~~]e~~~ 23-7); poly(oxy-1.2~elhsnediyl).
alpha -12-
omega -hydfok-y- (56372s
[etnyi~(umlem~w~n~openlyt)sulfonyl~-.omega
-hydfow
(68298-80-6): polyethylene glywl(25322-68-3);
water (7732-18-s)
Cakegory 3 In the original submission 3M daimed CBI We now release th at claim No substantiation protide, d
.a
1.4~dioxane (123-91-l); heptaacalluom-l-octanesuttonic
add (176523
1): linear n-ethyl paffl wrooctanesuJfonamlUe
(4151-50-2): n-
ethylpe~u~ane~lf~wramidalhyr
akohol(1691-99-2):
poly(oxy-1.E
elhanediyl). .alphe ~Z~elhyl[~ptadecaRuof~t)s~f~~]a~~~~t~
.omcga hyclrowy- (29117-08-6). lernyqfnonanuorob~l~~~]a~~Je~~~
paly(oxy-1.2~etbanediyt),
.alpha -[2-
omega -hydmxy- (6829879
3): poly(o~-i.2-ethaniyl).
atpIIa -fZ-
~eihyf[(~~adecatluMoheptyl)uRlonylJami (68298-81-7): poly(oxy-1.2-etbmMiyihanedivl). .alpba.-[2-
:hydrow-
[at~[(eidecSrtuwohe~~~y~~~]~hyl~.o~a
-bydfoXy- (56372.
23-T); pDiy(wy-I .2-etJlaned&l). .alplm j2-
lemyiI(~UuMqn"~~o~i~~~f~.om~.~y~~-
(68298-80-6). ~Dlyelhykf~ QI~COI (2532268.3). waler (7732-18-5)
Dibutyitin tautate (GAS 77-58-7). Oibotyitindi(2 ethylheroatef (CAS
2781-10-4)
IDecosheen
Blue in Green Cerer Blue ZV {GAS 61814-09-3).
Decosheen Royat Blue, Solvent Blue (CAS 1325-86-6): Decosheen Gold
Paste Pigment (CAS Number Unsvsilebfe)
IWaterlCAS 7732-18-5). Stoddard Solvent (CAS 8052-41-3): Sodium
Silic&(CAS
t344-09& Potassium tiyd&de fCAS 13iiJk8-3):
NonylpheMxypoly(orleVlylene)ema"~
(CAS 9016-45-g)
Category 2 In the ofiginat submission 3M daimed CBI We t w w release th; at daim No substantiation protidec 9
I I
cetegory 2 No change to submkian No wbstantiatim?providad CsteQwy 2 No change to submitsion No aubstanfialion provided ..A kXeaow 2 Nochange to submission. No subslantiation pwfided
Scratch Remover (Fathead Mmnow) lsnd Water Parbtion Coefftdent
60-79% Water. 20.36% 3% Turgitot NP-33
Stoddard
Sotvent. 15% Sodium SiMte:
O.i- Waler (CAS 7732-VJ-5). Silicate (CAS 1344-09-8):
I_Stoddard Solvent (CAS 8052-41-3);
Turgitol NP-33 (CAS 9016-45-9)
N-methytperfworvoctane
sulfonamidoethanot
CAS 24448-09-7
1Cl2 6H20 ?age"t
.___as CM+ Toxicity
to Miaotox
Cobalt (as Co2+ ion) (CoCIZ 6H20)
Bvated Sludge Respiration CoCl2 6H20 as Co ion
lnhibdian Test Cobalt (as CoZ+ ion) (CoCl2 6H20)
CAS 7791-13-I -
GAS 7791-13-1
: Study contains chemical identity or trade name CB1
Study contains personnel and other 3M internal CBI
3: Study contains no CBI
1
Sodium
calegoly 2 No change lo submission. No substantiation provided
caIegofy 2
-l
Na change to submission No
wbslantiation provided
~ category3 No change to subtwaion No subslantiation provided
Category 3 NO cnange to submission No subslantiation orwided
-I
Attachment #2
48
October 10, 2005 2nd Revision to Master fndex to Studies Submitted Under TSW 8(e) by 3M Company on October 26, 2004
.
(Confidential Business Information Redacted)
,
1 st Revision - March 11) 2005
.'
.
,
d
Acute Toxidty of CoC12.6H20 as Co ion lo Cobalt (as Co2+ ton) (CoCl2 6H20)
d 15926A CDoanp&hniolens magna under Static Exp~X.ura I
A&e Toxic&y of CoCX6H20 as Co ion lo Cobal (as Co2+ Ion) (CoC12.6H20)
Fathead Minnow under Static Expusure
I5927A Conditions
Freshwater Algae Growth Inhibition Test Cobalt (as C02+ ion) (COCt2.6H20)
,AS 7791-13-I xs 7791-13-l AS 7791-13-l
I Category 3 No change lo'wbmissio" No substantiation pmwded
cetegory 3 No change to submission. No subslankatiin is provided
Category 3 No change to submission No substantiation is provided
1592949 rir;produ&study
-
Planl Grcalh Effects of I)
I 5930A
Final Report (Daphoia
and Microlox)
8% water (7732-18-5).
t
1
12% dielhytene gtycol butyl ether(llZ-34-5)
MoeMethyl ether of hydroquinone
:A$ 1691-99-2
1% water (7732-18-5). 1
:A$ 150-765
12% diethytene glycol butyl ether (112-34-51.
We am mquesllng this study be puled from the submlsslon.
Category 1 Trade Secret Mcdure Subslantiation provided
CItegory 3 No change lo submission No
I5931A Micmtox Test Results
2 Ethylhexyt AC@&?; Isooctyl Acqtele Monomer; 2-Methylbutyl aaylale: Methyl isoamyi euvfate; lsaodyi Acsylate
Elhylhekyt Auytate (CAS 103-l l-7); lsooctyi Acqlate Monomer (CAS 95gO42-9) 2-Methytbutyt aaylete (CAS 44934-026): Methyl isoemyt aylafe (CAS 7899392-l): Isoociyf Acrylate (CAS 2959042-S)
substantiation is provided.
Cabzgory 2 No change to submissiwt. NO substanbabon provided.
I5932A I5933A 15951A
Phytotoxicity Tesl Results
PlsntToxidty GKWth
Comparison.
You"g Seedling
Cedodaphnia dubia Survival and Reproduction exposed to Opequw, Creek
Waler Spiked wih BET2 1110 POlymer (November 4.1987 sample) for seven days under static renewal conditions
81% water [773.2-18-S):
I
1
1
I
12% diethylene
glymt butyt ether(liZ-34-S)
81% water (7732-V-S).
I
1
12% diethytene gtycol btttyt elher (117-34-51,
BETZ 1110: Non-3M Produd - Chemical compositioft 3M by manufacturer
not provided to
1% water (7732-18-S). 1
12% dtethytene glycoi bulyt elher (112-34-5).
1% water (7732-18-S), i
12% diethyfene gfycol butyl ether (112-34-5):
lSDS provided by manufacturer states produet is `not hazardous" and 01 "considered to be a carcinogen"
Category 1 Trade Serxel Mixture Subslantiatio" provided
category 1 Trade Secret Mixhm Substantiation provided
not 3M MabXiai - MSDS from BET2 provided
15952A
Cedodaphnia Repmduclton
dubia Survival and exposed to Opequon Ctack
BETZ 1138: No"-3M Product -Chemical mmpasttioo not provided (0 1SDS provided by manufadurer states product is `not hazardous- and not 3M Material - MSDS from
3M by manvladurer
ol "considered to be a carcinogen'
BETZ provided
Water Spiked with Betz 1138 Polymer
(November 4.1987 sample) fr# seven days
under siaticfenewal wnchtions
I5953A t_5. 954A 1_-5-9_5-_5_A
IToxidty of 1.6 - Heranediol Daphnia magna
Diaaylate to
Daphnia magna Chronic Bioassay Under Static Renewal Condilions
Esttmating the Chronic loxicity of Naldear
7 177 lo Ceriodaphnia Sutviva~ and
tRqxoduchn" Using Shott-Term Tests
1.6 Hexanedid diaqla\e
I 1Uethyt isoamyl acqtale
Natdear 7177 wastewaler treatment an-yiemidclacxylate polymerChemical CMnpositioti not provided to 3M by manufacfu~r
Ilsooctyl Acrylate Monomer
:AS 13048-33-4 :AS 18993-92-l :qS InformaIm" not provided to 3M by manufacturer
.A$ 29590-42-9
_~~~~~__.
CJRBOV 3 No change to submisslon. No substantiation provided
C&gO,y 3 No change to submission. No substantiation provided.
not 3M Material - Nalu, Ltd emital information provided
Calegofy 2 No change to submission No substantialron provided.
:ategory 7 Slrrdy contains chemical identity or trade name CB1
Category 2 Study contains personnel and other 3M internal Cl31
Category 3' Study contains no C6l
2
.
.
October 10, 2005 2nd Revision to Master Index to Studies Submitted Under TSCA 8(e) by 3M Company on October 26, 2004
.'
(Confidential Business Information Redacted)
1st Revision - March 11, 2005
*
.
I
!1596OA
I
15961A
15962A
--
Static AcUlc Toxicity d ( ) to the Fathead Minnow. Pimepheles pmmelas
Slatic AcuteToddty Daphnia magna
of I} lo the Daphnid.
koocty1 ecrylate. Fish. Acute Toxicity Test
59% Waler (7732-18.5).
[
.watec proWlenelebaRuoroelhyfene
Isooctyl Aqtale Monomer
I polymer; teft-buiyi alcdml
15974A 15975A 15976A 15977A
IwoctyI Amylate: Daphnia sp. AMe Immobilization Test
t!xzwtyl AayIale. T&
Alga. Growth Inhibition
Isooctyt Aaytate: Tesl
Daphnia
sp. Reproduction
Acute ToXrcXy of 3M Prep Team to the mysid. bfysidopsls bahia
IsooctyI Acrytate Monomer
lsoodg Aaylale Monomer
tsoodyr Aaytate Monomer
I?CMX, alkyI-Z.~-imtnobisethanof; oaylphenonypdyalhoayelhyiphosphnte; hydroxtde: sodium lauryt ether
s&fats:
sodium trisodium
cabmat+: s&turn adta; water
15978A Fhat Report (Microlox)
(I-OXO altyl-2.2-iminobisethanol; o~lphenoxypolyeleth~~o~hal~; hydroxide: sodium tauqi ether sulfate;
Sodium b&odium
carbonate: sodium e&e; water
15979A 1598OA 15981A
15982A
Deteninstmn of the Partition CoeiTtcient OctandNVeter) of T-5896 by High Performance Liquid Chromatography
W'W
OECD Activaled Siudge Respiration InhibItion Test Results
(N. N-methyl pemuorwdane sulfonamide ethanol; pwftuofoodana sulfonamidethyt wytate
N-Dodecylt~methylammonium
chloride
N-methyl
Final Report (Fish Acule Toxicity)
Mirataine CB (30% Cocamidopropyi be&Ins = Amides. utco. N-(3-
(dimethylamino)propyl).
atkylation products with cJ#toroacettc add.
sodium salts. 70% Water and tnerfs): Miratalne COB (30%
Coco/Oleamidopmpyl
Belaine = I-Propanaminium. 3-amino-N-
(ca~oxymethvl)-N.N-dime~yl-.
N-DOM acyl de&s . inner salt)
A flow-Through Life-CycJe Toxtcify Test With the Sslhvater Mysid (Afysidopsis
PemuomocIane sulfonale
59% Waler t?732-18-5):
f
I
water (7732-M-5): propylene-tetmfluoroathylbne tert-butyI aIDJb0l(75-65-O)
GAS 29599-42-9
potymer (27029-05-6~
CAS 29593-42-9
GAS 2959042-9
CAS 2959042-S
n-caa? al&K?.2'-tminobisethatanol
(cas 61791-31-s);
&ytpheno~tyethoxyethytphosphat%
(~8s 5262s9S7);
ctarbonete (car 497-i 9-8); sodium hydroxide (1310-73-2);
sodturn sodium tauryl
ethar sulfate (9LlCbMZii); trisoclium edta (15036-9); water (7732-18.5)
Trade Secret Mixlwa Subsfentalion provided
cate0ory 3 Trade Sac-rat Mixtan
Substantiation provided
Category 1 Trade Sacret Substantiation
Trade Name provided
C*blgoly 2 NO change IO %h?k.sh. NO substantiation provided.
Catagory 2
No dtange to submisston No substantiation providad.
category 2 No change to submlssion. No
substantiation provided.
cataoon 2
No change to submisslo& No
substantiation provided.
CMlr@wy 3 In the original submission 3M daimed CBI . We now mkase Mat daim. No substantiation protided.
n-wco slkyf-Z.Timinobis+lhinot
(CBS 61791-31-9);
odytphenaxypolyethoxjMhyl~sphate
(EBS S2623%?): so&urn
&onate (cas 491-K+
sodiumhydroxide
(1316-73-Z); sodiumiautyl
ether&ate (9004-82-4); t&odium edts (15638-9); water (7732-18-5)
c*tegoy 3 In the originat submission 3M dabned CBI We f~hy release that claim. No substantiation provided.
N-methyl perfluorwztane methyl pedtuomoctane
suffonemido urlfonamidethyt
Manot (CAS 25268-77-3): Nauyiate (CAS 24448-c)9-7)
cats@O~ 3 No change to submission. No substantiation provided.
CAS = 112-00-5
Cocamidopmpyl belaine (GAS 70851-07-S); Betsine (GAS 61789-40-0~
CocolOlsamidopropyt
cdmpxy 3 No change to submission. NO subslantistion provided
c~tegoly 3 No change to wbmisston. No substantiation provided.
CAS 1763-23-l
I
EItegoly 3
In the original submission 3M
daimed CBI We nav release that
claim. No substantiation provided
Category 2: Study contains personnel and other 3M internal CBI
. Caiegory 3: Study con:ains no CSI
3
October
10, 2005 2nd Revision
to Master index to Studies Submitted Under (Confidential Business Information
1st Revision - March 11, 2005
TSCA 8(e) Redacted)
by 3M Company
on October
26. 2004
d
ILithium: Alga, Acute &city Tests
(Lithium Chloride
--
Q
15984A 1
I
iAfl E&v Life&tape Toxicitv Test With the ~Perftoorcactane sulfonate
F&head Minnow iPim?ph.?ies prmelas)
1598%
15986A Lithium: Fish, Acute foxidty Tests
Lllhfum Chlorfde
15987A 15986A
Uthium: Oaphnia , Acute foticity Tests Summsty 01 Toxicity Testing on OSCI and OSF
Toxicity to MkrotoxTest
Lithium Octane
Chloride sulfonyl
chloffde
and Octane
sulfonyt
flwride
Lawyfdimethytami~xide
15989A
1
Ecotodcabqicel Co2+ ion (Seed
Testing 01 CoC12.6H20 Germinalion and Root
es Cobalt (as Co2+ ion) (CoC12.6H20)
I
CAS 7447-41-B t
I
ICAS 1763-23-l
s"bsIe"ti&io"
provided.
ICategory 5 In the origind submission 3M dalmed CBI _ We now release that d&m. No substantiation provided.
CAS 5447.418
calegory 3
No dmge to submissIOn. No substmdietion provided.
IxegoIy 1
No change to submiulon No
CM 7447-41-0
subftantiation Provided.
Octane wlfonyl ftuodde (CAS 7795-95-l), Octane sulfonyl chloride (CAS Category 3
4063-63-5)
No dump to submition. No
substantiation fxovided.
CAS 1643-20-5
catagory 3 No dmae lo SubmissIon. No substanjation provided.
CAS 7791-13-l
I
cmwY 3
Nodwnge tosvbmiuion
No
~subslantiation provided.
1
.
.
."
&v
Category 1: Study contains chemicdl identity or trade name CBt
Category 2: Study contains personnel and other 3M internal CBI
d Category 3: Study contains no CBI
4
,
`_T
,.
Larry R. Zobel, MD MPH St `hi Vice Prcsidcnt aml Mcdicai Dirccmr
31 Medical Departniant
3M Csntct; Building 0220~Oh-W-OX St. Peul, MN 55 144-I(X)0
651 733 5181 Ofiirc 651 733 5152 Rx
3nll Certified Mail
November 16,2005
Re: TSCA Section 8(e) Supplemental Submissions: Docket Nos. 8EHO- 1180-373 .and8EHOY118.0-374
Dear Sir/Madam:
3M has previously submitted analytical resultsfor serum measurements of various
fluorochemicals. As a supplement to those submissions,3M provides additional resultsas described below.
Two female fluorochemical plant workers provided 3M with serum samplesfor their children through their private physicians and,requestedthat 3M analyzethe saniples. A total of three children were sampled, one'time each. To,the best of 3M's understanding, the children were
approjrimately 8 months, ten months and two years of age at the time of sampling. At the time,
the workers participated in 3M's occupational medical surveillance-program for
fluorochemicals. This program does not include children, .The sampling was done at the
request of the mothers.
Worker #I had one child sampled, in the fall of 2000, when the,child was about 10 monthsold. The morher's blood was sampled in the fall of 1998, and again in 2000, several months afier
the baby's birth, aspart of the regularly scheduled occupational monitoring. Thus, the maternal levels are provided here to offer some context, but they do not represent immediate prepregnancy, gestational, or i&mediate post-partum levels.
Worker # 2 has two children. Child A was a1sosampled in the fall of 2000, at approximately age 2. The sample from 2000 was re-analyzed with improved analytical techniques in 2002,' Child I3 was about 8 months old when sampledin the fall of 2002. Maternal values are
available from the fall of 1998, March 2000, and June 2002, and as with worker #I, are provided to offer general context.
Sampling results are shdwn in the tables below. For results below the Lower Limit of GZ?
Quan@ication (LLOQ) of the analytical method, the quantification limit for the chemical s
(where available) is shown in parenthesis.
c7
Iilllll IllIlflIlill!llIlIlIilHlMlilll~ll~lIll1lil1l111 600800000B8
..- .--
-__-...
I .~.,
a
- ..,'
l Document Procarrtng Center (Mril Code 74Q7M) P*gr 2
WORKER #I CHILD (Approxilziately 10 months old when sampIe collected in Fall 2000)
ANALYTE Perfluorooctanesulfonate (PFOS) Perfluorooctanoate (PFOA) Perfluorohexanesulfonate (PFHS) N-ethyl perfluorooctanesulfonamidoacetate (PFOSAA) I N-methyl perfluorooctanesulfonamidoacetate (M570) Perfluorooctanesulfonamide (PFOSA)
Perfluorooctanesulfonamidoacetatc (MS56)
I
RESULTS (ppm)
Less than LLOQ (0.040)
0.055
0.01 I
0.008
0.007
Less than LLQQ (0,001) I
Less than LLOQ (0.004)
I
WORKER #1
I *
I
ANALYTE
RESULTS (ppm)
Perfluorooctanesulfonate (PFOS) Perfluorooctanoate (PFOA) Perfluorohexanesulfonate (PFHS) N-ethyl perfluorooctanesulfonamido&etate (PFOSAA) N-methyl perfluorooctanesulfonamidoacetate (MS70) Perfluorooctanesulfonamide (PFOSA) i%rfluorqoctanesulfonamidoacetate (M.556)
Nov. 1998 Sample 0.146 0.069 0.026 0.018 0.032 Below LLOQ 0.004
March 2000 Sample 0.117 0.338 0.026 0,008 0.029 Below LLOQ (0.001) 0.013
.
.,
,".. -.-._.
" ,_ ._-
I -_,
c3
(Approximately
WORKER #2 CHILD A 2 years old when sample collect&d in Fall 2000)
ANALYTE
RESULTS (ppm)
2000 Method
Perfluorooctanesulfona(tPeFOS) Perfluorooctanoat(ePFOA) Perfluorohexanesulfona(tPeFHS) N-ethyl perfluorooctanesuffonamidoace(tPaFteOSAA)
N-methyIpertluorooctanesulfonamidoace(taMte570) Perfluorooctanesuifonami(dPeFOSA)
Ferfluorooctanesulfonamidoace(taMte556)
0.171.
0.195
0,064
BelowLLOQ
(0.006)
0,009 Below LLOQ (0.001)
0.008
Reanalysis of2000 Sampling with2002
Method
0.183
0.138
0.054 0.005
0.007 n/a
nfa
(Approximately
WORKER #2 CHILD B 8 months old when sample collected in Fall 2002)
ANALYTE Perfluorooctanesulfona(tPeFOS) Perfluorooctanoat(ePFOA) Pertluorohexanesulfona(tPeFHS) N-ethyl perfluorooctanesulfonamidoace(tPaFteOSAA) N-methyl perfluorooctanesulfonamidoace(tMatSe70)
0.169 0.224 0.028 0.008 0.007
RESULTS (ppm)
`Dckxmem Page 4
:rocrrkg
Center (MaIf Coda 740784)
WORKER #2
ANALj'TE
Perfkorooctanesulfonat(ePFOS) t
Perfluorooctanoat(ePFOA) Pefluorohexanesulfonat(ePFHS) N-ethyl perfluorooctanesuifonamidoace(tPatFeOSAA) N-methylperfluorooctanesuifonamidoace(tMat5e70) Perfluorooctanesulfonarni(dPeFOSA) Perfluorooctanesulfonamiadcoetate'(M556)
Nov. 1998 Sampte 0.091 0.022 0.013 BelowLLOQ
0.006
Below LLOQ
Below LLOQ
RESULTS (ppm) March 2000 Sample INO? reanalysis]
9.161[0.142-j 0.082[0.067)] 0.018[O.OlS] 0.020[0.015]
0.057.[0.054]
&low LLOQ (0.001) [n/a] 0.012[n/a]
June 2002 Sample
0.090 0.025 0.009 BelowLLOQ (0.004) Below LLOQ (0.057) n/a
n/a
3M does not believe that thesedata meet the TSCA Section 8(e) "substantial, risk" reporting threshold. In our view, thesedata are limited and provide no basis to draw any scientific c&elusions. Nevertheless, 3M has decided to submit these data to the 8(e) docket, with the consent of the two workers, recognizing the ongoing work by U.S. EPA to assess fluorochemical exposure pathways and potential risks.
If you have any questions, pleasedo not hesitateto contact Dr. Larry Zobel, at (65 1) 733-S181,
Sincerely,
Staff Vice President and Medical Director 3M Medical Department,
