Document 6BmJ75a99oj8pVr2pwpaXB21R

bcc: A. R. Hcmpel - Chgo 0. L. Hosmer - Chgo _Aprl} 16, 1965 Mi'. M. K. Young Jilectrio Auto Lit* Voodatock Dia Casting Company Woodstock, Illinois Doar Mr. Young 1 Dais uaith has askod .-as to forward toxicity and safe handling Information for Pydraul A-200. Animal toxicity studios with this product havs indicated tliat the oral lethal dose (Ufeo) to rats is 10,500 milligrams per kilogram. Ihe lethal dose when the material was applied undiluted to the unbroken skin of rabbits Is approximately 1250 milligrams par kilogram. We conolude from the above that aooldental ingestion on the part of humans la not a particular hasard in vlati of the nigh oral lethal doee in rate. 3imllarly, eingle massive skin expoeures should not be mediately hazardous. The lethal dose obtained in skin penetration studies is such, however, that prolong.; and repeated skin contact should be avoided because of possible systemic effects. In addition, prolonged and repeated skin contact may lead to skin Irritation. ws alao feal that vapor initalatlan should be avoided when tl* fluid le heated to elevated temperatures, Such exposure again relates to prolonged or repeated expoeuree rather than short-term massive or acute expoeuree. In the eaee of the latter, workmen would not voluntarily expose themselves to concentrations that are hazardous because of irritation of the respiratory tract. The use of Pydraul A-200 in industrial hydraulic fluid appli cations should not present toxicity hssards during tit* trsnufer of the fluid from original containers to the hydraulic aystem. Obviously when tha fluid is within the hydraulic oyatem, there should be 00 exposure and consequently, no hasard. In the event of rupture of hydraulic lines and subsequent splashing or spraying of the fluid on the heated NUNS 09116U f ilr, .1. .1. Ifou/u April io, ijio v'ajo 2 surfaces, vapors of tho fluid and possible decomposition products (depending on the temperature of the heated surface) my be irritating if inhaled to the uotyoe that uorkr.M>n will not voluntarily expose themselves to tootle concentrations. No hazardous exposure should result during tho interval required to shut down tho system and obtain suitable respiratory protective novices during repairs to the system. If X can be of any further assistance, ploase do not hesi tate to let me know. Very truly yours. ,,, tru JM9CsmJb cci Dale bmlth R. Emmet Kelly, H.D. Medical Dlroctor ONs 91169