Document 6BXk79B959a7xnGGn4eRzO97m

496 INDUSTRIAL HYGIENE AND OCCUPATIONAL MEDICINE studies of lead workers (Cotter x) showed no significant changes in their blood chemistry, these cases were included in the series. The series is believed to be of interest also because it was possible to follow the patients for many months and to repeat some of the laboratory work. Briefly, the method employed for quantitating cadmium in blood and urine was based on the fact that dithizone (diphenylthiocarbazone) disintegrates at pH 11 except in the presence of an excess of cadmium.2 REPORT OF CASES Case 1.--T. V., a 35 year old white man, worked as a burner of clean and painted steel for seven years. In the process of converting a ship, he encountered numerous cables running through the bulkhead he was clearing; which gave off an irritating gas as he burned them. After Table 1.--Laboratory Data Obtained After the Patient Emerged from Coma Substance or Test Amount or Reaction Blood sugar ............ ............ 74 Serum cholesterol ............... 250 Free cholesterol ................. 98 Cholesterol esters ............... 152 mg./lOO.cc. Serum phosphorus ............. 3.2 Serum nonprotein nitrogen 33 Serum uric acid.................. 7.3 & Serum calcium .............................................................................................. 6.1' Serum halogen ............................................................................................. Serum carbon dioxide.......;........................................................................ 108 25 mEq./l. Serum sodium .................................................. ........................................ i. 143 Serum alkaline phosphatase V Serum total protein .......... Scrum albumin .................... Serum globulin .................... Scrum euglobulin .............. Serum pseudoglobulins ___ '4 Blood cadmium .................. Urine cadmium .................. 0.4 Bodansky unlts/100 cc. 7.7 4.7 3.0 Gm./lOO cc. 0.5 2.5 0.18 mg./lOO Gm. 0.10 mg./l. Hematological Findings R. B. C. .......................... Hgb................................... W. B. 0........................... Differential count h Neutrophils .............. Monocytes ............... Lymphocytes .......... Basophils ................. Reticulocytes .......... 3,300,000 14 Gm./lOO cc. 5,700 56 4 34 1 % 2 a four hours in this atmosphere he had a terrific headache and went into a coma. The plant doctor a who saw him made a ' provisional diagnosis of carbon monoxide poisoning and withdrew a sample of blood under oil which he submitted to one of us (L. H. C.) for analysis when he '.V- referred the case for further study. Only 1 vol. per cent of carbon monoxide was found. When the patient was next seen, he had recovered consciousness. He was sweating profusely, and his pulse and respirations were rapid. There was no congestion of his mucous membranes, 'M !d: ho lead line, no abdominal tenderness and no muscle weakness. 1. Cotter, L. H.: Lead Intoxication by Inhalation,. J. Indust. Hyg. & Toxicol. 28:44-46 (March) 1946. 1c 2, Church, F. W.: A .Mixed Color Method for the Determination of Cadmium in Air and ij Biological Samples by the Use of Dithizone, J. Indust. Hyg. & Toxicol. 129:34-40 (Jan.) 1947.