Document 6BVxqL56mpgjMegO09JoXzw29

FILE NAME: Oil Industry and American Petroleum Institute (API) DATE: 1962 Apr 9 DOC#: API048 DOCUMENT DESCRIPTION: Minutes from API Medical Advisory Committee Meeting with Attachments DIVISICI! OF TECHNICAL SERVICES AMERICAN PETROLEUM INSTITUTE AGENDA MEDICAL ADVISORY COMMITTEE Monday, April 9 > 1962 9:00 A. M. Buckingham Room (Third Floor) Pick-Congress Hotel Chicago, Illinois I. Opening Remarks II. III. Introduction of New Members and Guests Approval of November 13, 1961 Minutes (a) IV. Subcommittee Reports Operating Subcommittee ( b ) Atmospheric Pollutants ( 0 ) C9 - Cj2 Aromatics - R. F. Schneider, M. D. - C. L. Samuelson, M. D. - Kieffer Davis, M. D. (d) Certificates of Appreciation - R. E. Eckardt, M. D. ( e ) Dermatology ( f ) Epidemiology - J. W. Osborn, M. D. - G. M. Saunders, M. D. (g) Industrial Hygiene ( h ) Medical Policies and - J. A. Spence Administrative Practices - V. C. Baird, M. D. (1) Physical Agents - G. H. Collings, M. D. 00(j) Specialty Petroleum Products - C. H. Baylor, M. D. Toxicological Reviews - H. W. Gerarde, M. D. (a) V. Liaison Members Air and Water Conservation Committee - C. L. Samuelson, M. D. (b) Interdivisional Committee on Asphalt - J. A. Spence (0) Interdivisional Committee on Labeling - A. E. Dooley ( d ) Oil Mist Liaison Committee - N. V. Hendricks ( e ) Interdivisional Committee on Petroleum Food Additives - L. E. Curtis, M. D. ( f ) Quarantine Service ( g ) Advisory Committee to the Wax Research Project - G. M. Saunders, M. D. - R. E. Eckardt, M. D. ( h ) National Poison Prevention Week - J. W. Osborn, M. D. (1) Walsh-Healey Public Contracts Act - W. L. Avrett, Jr. (J) U. S. Public Health Service Liaison Activities Air Pollution - C. L. Samuelson, M. D. Dermatology - J. W. Osborn, M. D. Epidemiology Industrial Hygiene - G. M. Saunders, M. D. - J. A. Spence Physical Agents Toxicology - G. H. Collings, M. D. - H. W. Gerarde, M. D. API 07739 MEDICAI, ADVT30R COMMUTEE AGENDA (Ccr.tir.ued) VT. Relation of Medicai Advisory Corsaittee and General Committee of Division :f Technical Services VII. Possi eie Reorganization of Medical Advisory Committee VIII. 1963 Budget IX. New Business X. Adjournment API 07740 r 'r-- 3 T," L"rr,A."T_rC'' AMER. :v: r V-r-^'T^S MEDICAL ADVISORY COMMITTEE 2 93 R:0D0 MEA.ETMI.NG Monday, April 9 > 19^2 Pick-Congress Hotel, Chicago, Illinois MEMBERS PRESENT: R. F. Schneider, M. D . , Chairman G. H. Collings, Jr., M. D., Vice Chairman J. W. Hammond, Secretary T. E. Allen, M. D. V. C. Baird, M. D. C. H. Baylor, M. D. F. F. Boys, M. D. L. E. Curtis, M. D. (Represented by James Ryan, M. D.) Kieffer Davis, M. D. F. D. Gassaway, M. D. E. V. Henson, M. D. E. K. Linder, M. D. J. W. Osborn, M. D. M. R. Plancey, M. D. Stewart L. Rankin, M. D. G. M. Saunders, M. D. (Represented by J. B. Rather, G. A. Sinclair, M. D. W. Wayne Stewart, M. D. R. A. Wise, M. D. Jr.) TECHNICAL ADVISORS PRESENT: W. H. Barcus H. W. Gerarde, M. D. P. D. Halley N. V. Hendricks P. K. Kuhne (Represented by A. C. Miller) J. A. Spence MEMBERS ABSENT: J. W. Crookshank, M. D. ?.. R. Dugan, M. D. H. E. Eckardt, M. D. H. R. Fourcher, M. D. ?. Emmet Kelly, M. D. T. J. Kelly, M. D. Z. ?. Luengo, M. D. B. S. Miller, M. D. R. J. Potts, M. D. J. C. Ruddock, M. D. C. L. Samuelson, M. D. L. W. Sanders, M. D. Kendrick Smith, M. D. H. B. Snyder, M. D. CTIERS PRESENT: A. C. Currier, M, D. Helmut Herrmann, M. D. . Z. 1I-. Hollis, M. Mattocks D. H5.. 3Van Basite, M. D. , Reeve, M. D. Pc-ver Swsr. , M. D. 1 . ORBITING REMARKS - Standard Oil Company of California, Richmond, Calif. - Esso A. G., Hamburg, Germany - Faillips Petroleum Company, Phillips, Texas _ Staff, American Petroleum Institute, New York , N. Y. - Royal Dutch Shell, The Hague, Netherlands - Retired - Es=c Pstrclsum Ltd., London, England API 07741 ZC *'O'T D. , Chairman zi the Med: :al Adviser;/ Committee, visiter: V . m : :andane Cil Company of i r.glsr.d; H. Yer. Raalte . .t Hermann, M. B. , Zee; C. , ?-yal Dutch Shell, A. G. , Hamburg, Germany; The and 3Hague, . B. Reeve, c.y* M-dicsl '\Z.","Lb z t y Ccrr.ittee. pQ^Tp ship: Chairman Schneider announced the following changes in committee member New Cfficers: R. F. Schneider, M. D., Chairman G. H. Ceilings, Jr., M. D., Vice Chairman J. W. Hammond, Secretary New Medical Advisory Committee Members: H. B. Snyder, M. D., Humble Oil & Refining Company R. A. Wise, M. D., Humble Oil & Refining Company Kendrick Smith, M. D., Tidewater Oil Company New Technical Advisors to Medical Advisory Committee: R. C. Burton, M. D., American Oil Company J. P. Malia, M. D., American Oil Company T. G. Nevins, M. D., Humble Oil & Refining Company T. H. Mitchell, M. D. Humble Oil & Refining Company . W. A. Rowe, M. D. , Humble Oil & Refining Company W. D. Seyfried, Humble Oil & Refining Company R. P. Sim, M. D., Humble Oil & Refining Company Wm. B. Townsend, M. D., Humble Oil & Refining Company C. E. Fountain, Tidewater Oil Company III. APPROVAL OF MINUTES ACTION: It was regularly moved, seconded, and unanimously passed 32 that the minutes of the nd meeting of the Medical 19 1 Advisory Committee, held November 13, & , be approved as distributed. IV. SUBCOMMITTEE REPORTS A. Operating Subcommittee R. F. Schneider, M. D., Chairman, reported that the considerations of the Operating Subcommittee will be brought up under the various agenda items so there is no need for separate action. The minutes of the Operating Subcommittee are attached as Appendix A. 3 . Atmospheric Pollutants T. E. Allen, M. D. , reported for C. L. Samuelson, M. D., chairman of the subcommittee. The subcommittee report is attached as Appendix B. ACTION: It was regularly moved, seconded, and unanimously passed that the reoert of the subcommittee and the recommendations therein be approved. API 07742 I Zc - Z- 2 Aromatics The report of Kieffer DBvis, M. D. , Chairman of this subcommittee, was read. A copy of the report is attached as Appendix C. ACTION: It was regularly moved, seconded, and unanimously passed that the report be accepted. D. Certificates of Appreciation In the absence of R. E. Eckardt, M. D., Chairman, it was stated that there was nothing to report. E. Dermatology J. W. Osborn, M. D., presented the report of this group, a copy of which is attached as Appendix D. ACTION: It was regularly moved, seconded, and unanimously passed that the report be accepted. F. Epidemiology T. E. Allen, M. D. , reported for G. M. Saunders, M. D., Chairman of the Subcommittee. Since the subcommittee had no meeting, there was nothing specific to report. G. Industrial Hygiene J. A. Spence, Chairman, gave the report of this subcommittee. A copy of his report is attached as Appendix E. ACTION: It was regularly moved, seconded, and unanimously passed that the report be accepted. H. Medical Policies and Administrative Practices G. A. Sinclair, M. D., reported for V. C. Baird, M. D., Chairman. The report of this group is attached as Appendix F. ACTION: It was regularly moved, seconded, and unanimously passed that the report be accepted. I. Physical Agents G. H. Collings, Jr., M. D., Chairman, reported for this subcommittee. A copy of his report is attached as Appendix G. ACTION: It was regularly moved, seconded, and unanimously passed that the report be accepted. J. Specialty Petroleum Products C. H. Baylor, M. D., presented the report of this group, a copy of which is attached as Appendix H. API 07743 I N; It vs5 regularly moved, seconded, and unanimously passed Vo- 't* qo 2C^--p*--C . Toxicological Revievs H. W. Gerarae, M, D. , presented the report of this group, a copy of vhich is attached as Appendix I. ACTION: It was regularly moved, seconded, and unanimously passed that the report be accepted. L. Oil mist Inhalation Chairman Schneider stated that this group had been made a subcommittee of the Medical Advisory Committee, in place of a liaison committee. N. V. Hendricks gave his report, a copy of vhich is attached as Appendix J. ACTION: It vas regularly moved, seconded, and unanimously passed that the report be accepted. V. REPORT OF LIAISON MEMBERS A. Air and Water Conservation Committee R. F. Schneider, M. D., reported for C. L. Samuelson, M. D. vho had been appointed as the liaison member to the Division of Refining's Air and Water Conservation Committee. To obtain a better understanding of vhat the refining people were doing in the field of air pollution and to acquaint them vith the Medical Advisory Committee activities, a group informally known as the Liaison Group on Air me-t in New York on April H, 1961. Representing the Medical Advisory Committee vere R. F. Schneider, M. D.; C. L. Samuelson, M. D. ; R. E. Eckardt, M. D.; G. H. Collings, Jr,, M. D.; and J. W. Hammond. Representing the Division of Refining vere staff were L. W. C. J, Sweeney, K. F. Beaton, Burroughs, W. T. Gunn, E. 0Jerry McAfee, . Mattocks. J. R. MacGregor. From the The group spent considerable time in reviewing their various activities. The possibility of having a physician attend the CRC meeting, concerning air pollution, vas discussed. In general, the meeting appeared to be exceedingly fruitful in informing each other of the various activities vhich were being conducted in the different divisions of the API. Dr. Schneider stated that he expects that these informal meetings will be repeated. Dr. Collings thought that the MAC should place more emphasis on the use of Public Health Service funds which are available to do research work on air pol lution. 3 . Interdivisional Committee on Asphalt Dr. J. A. Spence stated that this group expects to have an organizational meeting within a month or so. He expects to invite Dr. Wes Horton, of Kettering, Cincinnati, to review the background work vhich they have done on the study of asphalt and heavy oil streams. C. Interdi visional Committee or. Labeling In the absence of Mr- A. E. Dccley, Chairman, his report, vhich is given as Appendix H, was read. API 07744 :ivi sirr.a. urn Feed Additives :es ?y; M. D,, repcrtec L. E. Curtis, M. D., Chairman, that there meeting of this committee and there was nothing to report. Quarantine Servic e T. E. Allen, M, D. , reported for G. M. Saunders, M. D., liaison member, whose report is attached as Appendix L. F. Advisory Committee to the Wax Research Project In the absence of R. E. Eckardt, M. D., the report for him was given. It is expected that the wax petition will be filed with the Food and Drug Administration within 60 to 90 days. G. National Poison Prevention Week J. W. Osborn, M. D., liaison, reported on this activity. His report is given as Appendix M. ACTION: It was regularly moved, seconded, and unanimously passed that the Medical Advisory Committee recommend to the General Committee of the Division of Technical Services that active participation in National Poison Prevention Week for 1963 be discussed with the API Oil Information Committee and the API Fire and Safety Committee so that a decision may be reached no later than November 1962 as to the petroleum industry's participation in the 1963 National Poison Prevention Week. It was suggested that the physicians consider recommending that their companies list, with the National Clearinghouse Poison Center, the name of one or more individuals who would be available to receive inquiries concerning their branded products. It was indicated that a couple of companies have done this and it has proved exceedingly effective. H. U. S. Public Health Service The following liaison people, with the Public Health Service, have been established with Dr. Anderson, Assistant Surgeon General: J. W. Osborn, M. D., Medical Advisory Committee; H. W. Gerarde, M. D., Toxicology; C. L. Samuelson, M. D., Air Pollution; J. A. Spence, Industrial Hygiene; G. M. Saunders, M. D., Epidemiology; J. W. Osborn, M. D. Dermatology; and G. H. Collings, Jr., M. D., Physical Agents. Chairman Schneider requested each of these liaison members to contact their corresponding member before the November meeting. The group expressed their appreciation to Mr. N. V. Hendricks for his great assistance in working out the liaiscr. representation with the Public Health Service. VI. rsiACIO:; CF MEDICAL ADVISORY COMMITTEE AND GENERAL CCMMITTEE, DIVISION OF API 07745 Chairman Schneider stated the March 1962 News Letter of the Division y clear fashion, the reorganization of the *n . Services. It also contained an organi che General Committee. There were r.o -- ter c or.ce s resrsa FCTSIBIZ rzcrganizati: v- -"V MMHITE One of the items on th- General Committee agenda, which is set for :-oril h, is the possible reorganization of the committees reporting to the General Committee. Since there are It committees reporting to the General 'cmmittee, it appears highly desirable to reduce this number. The possibility of ;reating four central committees, one on health, one on research, one on safety, ar.d one on engineering and standardization, might be considered. If there were a central committee on health, all the health activities could be channeled through -his committee. On the General Committee are seven physicians, with two additional physicians being chairmen of committees now reporting to the General Committee. These physicians plan to discuss the possible reorganization further, prior to the General Committee meeting. VIII. 1963 BUDGET Approved 1962 Chicago Medical School (Hydrocarbons in Lungs) Critical Review of Atmospheric Pollution Literature Study of Noise Oil Mist Epidemiology Consulting Fees $1+2 ,000 5,000 2,500 2,000 Recommended 1963 $1+2,000 25,,500000 10,000 2,000 $51,500 $61,500 ACTION: It was regularly moved, seconded, and unanimously passed that the suggested budget of $61,500 be approved. IX NEXT MEETING The chairman of the General Committee has indicated it will be necessary 1 2 fcr the General Committee of morning, November , 1962, the Division of Technical Services to meet on Monday With this schedule, it will be necessary for the Medical Advisory Committee to meet prior to this time. ACTION: It was regularly moved, seconded, and unanimously passed that the Medical Advisory Committee Subcommittees meet 9 19 2 Friday, November , ^ , and Saturday morning, November 1 0 19 2 , o , the Operating Subcommittee meet Saturday 1 0 1 9 6 2 evening, November , , and the Medical Advisory Com 1 1 mittee meet Sunday morning, November , 1962. The desirability of the subcommittees meeting consecutively so that all cf the physicians could attend all of the meetings rather than have some of them run concurrently, as at present, was discussed at length. ACTION: It was regularly moved, seconded, and unanimously passed that the subcommittees meet consecutively during the 1962 9:30 November meetings, starting at A. M., Friday 19 2 morning, November 9, c , and ending by r.oor. or. Saturday, API 07746 / !4 X , rrzw b u s z .^ss Tr.ere was no new business brought up by the group. A - . Jo wLru'ti'JLi.j X The meeting adjourned at 1 0 :U0 A. M. Approved: R. F. Scheider, M. D., Chairman May IT, l$fc2 J. W. Hammond, Secretary E. 0 . Mattocks, Recorder API 07747 I ; APPENDIX A yCR COMMITTEE USE ONLY NOT FOR PUBLICATION AMERICAN PETROLEUM INSTITUTE MINUTES OF THE MEDICAL ADVISORY COMMITTEE'S OPERAT6I:0N0G SUBCOMMITTEE P. M. Saturday, April 7 > I962 Pick-Congress Hotel, Chicago, Illinois MEMBERS PRESENT: R. F. Schneider, M. D., Chairman G. H. Collings, Jr., M. D., Vice Chairman J. W. Hammond, Secretary V. C. Baird, M. D. (Represented by G. A. Sinclair, M. D.) C. H. Baylor, M. D. L. E. Curtis, M. D. (PFA) (Represented by James Ryan, M. D.) Kieffer Davis, M. D. R. E. Eckardt, M. D. (Wax) H. W. Gerarde, M. D. N. E. V0.. Hendricks Mattocks (Oil Mist) (ex-officio) J. W. Osborn, M. D. C. L. Samuelson, M. D. G. M. Saunders, M. D. (Represented by T. E. Allen, M. D.) J. A. Spence (Asphalt) MEMBER ABSENT: A. E. Dooley (ICL) I. INTRODUCTORY REMARKS R. F. Schneider, M. D., Chairman, stated that G. A. Sinclair, M. D. was reporting for V. C. Baird, M. D.; T. E. Allen, M. D. for G. M. Saunders, M. D.; ar.d James Ryan, M. D. for L. E. Curtis, M. D. New officers of the Medical Advisory Committee were appointed the first of 1962 and are R. F. Schneider, M. D . , Chairman; G. H. Collings, Jr., M. D., Vice Chairman; and J. W. Hammond, Secretary. New Subcommittee Chairmen are R. E. Eckardt, M. D., Certificates of Appreciation; J. W. Osborn, M. D., Dermatology; V. C. Baird, M. D., Medical Policies and Admini strative Practices. II. APPROVAL OF LAST MINUTES ACTION: It was regularly that the minutes moved, of the 1 1 seconded, and unanimously passed November , 1961, meeting of the Operating Subcommittee be approved as distributed. III. REPORTS OF SUBCOMMITTEE CHAIRMEN A. Atmospheric Pollutants API 07748 C. L. Samuelson, M. D., Chairman, reported that his group recommends $U2,000 for 1963 to continue the investigation of the carcinogenic properties of certain polycyclic aromatic hydrocarbons, being conducted at the Chicago Medical School, 'under the direction of Philippe Shubik, M. D. The subcommittee also recommends that $5 ,0 0 0 be placed in the I9&3 budget to continue the critical review of literature relating to the medical aspects - 2- i Cq - Cj_2 Aromatics A-2 I Kieffer Davis, M. D., Chairman, reported that his group has no request 30 1 9 6 2 fcr money in 1963 since the project, under the be discontinued June , . He recommended direction of C. A. Nau, M. D., his subcommittee be maintained will to review any new proposals. C. Certificates of Appreciation R. E. Eckardt, M. D., Chairman, stated he had no request for money nor any policy matter to bring up for discussion. D. Dermatology J. W. Osborn, M. D., Chairman, stated that there appeared to be some confusion as to who was the new chairman of the Division of Marketing's Hygiene Panel of the Lubrication Committee. Because of this uncertainty, the Subcommittee on Dermatology plans to continue their contact with Mr. Floyd Van Atta, industrial hygienist of the United Auto Workers of America, in Detroit, Michigan. E. Epidemiology T. E. Allen, M. D., representing G. M. Saunders, M. D., Chairman of this group, reported they had no requests for money nor policy matters to bring up for discussion. F . Industrial Hygiene J. A. Spence, Chairman, reported his group had no request for money in 1963 nor policy matters to bring up for discussion. G. Medical Policies and Administrative Practices G. A. Sinclair, M. D., reporting for V. C. Baird, M. D., Chairman, stated the group had no request for money nor any policy matters to bring up for discussion. H. Oil Mist Mr. N. V. Hendricks, Chairman, reported his group believes they need experience data of people working in an atmosphere of oil mist. Contact has been made, with the Allis Chalmers Corporation to see if their medical records can be reviewed to determine the incidence of respiratory illness. To provide funds to mmaikteteesucrhecoammsetunddys, $1at0 ,0a0 0plbaecepltoacbeed determined as soon as possible, the subcom in the 1963 budget. The subcommittee hopes to have a firm recommendation at the November meeting. If possible, the subcommittee will try and obtain a grant from the Public Health Service to finance this study. Also, effort will be made to have the results of the study published. Chairman Schneider stated that he believed the Oil Mist group should be a subcommittee of the Medical Advisory Committee and stated that unless there was objection, the group will be called the Subcommittee on Oil Mist Inhalation. I. Physical Agents 07749 $2 , 5 0 0 be 1963 G. K. Ceilings, Jr., M. D., Chairman, placed in che budget tc continue stated this the support group recommended of Dr. Glcrig and tr.e J . Specialty Petroleum -Products C- H 3ayIor, M. D. , Chairman, repented this group had no request for mcney for 1963 tor ar.y policy matter to bring up for discussion. K. Toxicological Reviews H. W. Gerarde, M. D., Chairman, reported his group is recommending a policy change. If toxicological data are available from other sources on material pre viously reported by the API and if the Subcommittee on Toxicological Reviews finds the data sufficient for use by the petroleum industry, the API toxicological reviews will not be revised. The Subcommittee on Toxicological Reviews will spend its time preparing new toxicological reviews on petroleum products not previously included. If possible, the new ones will be prepared by the committee members but it is pos sible some money may be needed to get outside assistance in certain cases. IV. 1963 MEDICAL ADVISORY COMMITTEE BUDGET ACTION: It was regularly moved, seconded, and unanimously passed . that an amount of 2,000 be included in the budget to hire consultants, as the need arises. 1963 Medical Advisory Committee Budget Approved 1962 Recommended 1963 Chicago Medical School Critical Review of Atmospheric Pollution Literature Study of Noise Oil Mist Epidemiology Consulting Fees $1+2,000 5,000 2,500 2,000 $51,500 $1+2,000 5,000 2,500 10,000 2,000 $"1,500 ACTION; It was that a regularly budget of m$ov1e,5d0, 0 seconded, and unanimously be recommended for 1963* passed V. RZLATIOilSKI? OF MEDICAL ADVISORY COMMITTEE AND GENERAL COMMITTEE, DIVISION CF TECHNICAL SERVICES Chairman Schneider reported that the recent News Letter from the Division of Technical Services reported on the reasons for the formation of the new Division of Technical Services to replace the former Department of Technical Services. He ssked if there were any further questions. The News Letter appeared to have given s satisfactory explanation. VI. PCSSIH-S REORGANIZATION OF THE MEDICAL ADVISORY COMMITTEE Chairman Schneider explained that ar. item appears on the agenda of the General Committee which is to meet April lo on possible reorganization of the lU committees reporting to the General Committee. It is hoped that this number can be reduced in number. The desirability of forming a Central Committee on Health was reviewed. lo conclusions were drawn. API 07750 v i l . text meeting * A-k rnr.ir.g, 11 1 2 The Vice President cf the Divisitr. cf Technical cvesster , in Chicago, as the tine ci the fall Services meeting. has see Monday This will mean that the Medical Advisory Committee will have to meet before Monday. The desirability of having the subcommittees meet on Thursday and Friday, 9 November S and , and the Medical Advisory Committee on Saturday or Sunday, 10 1 1 November or , was discussed. The possibility of shortening the time for the subcommittee meetings was reviewed. ACTION: It was regularly moved, seconded, and unanimously passed that the Medical Advisory Committee subcommittees meet con 9 1 9 6 2 secutively starting Friday morning, November , , and 1 0 terminate by noon on Saturday, November , the Operating 1 0 Subcommittee meet Saturday evening, November , and the 1 1 Medical Advisory Committee meet Sunday morning, November . VIII. NEW BUSINESS A. Study of Petroleum Products G. H. Collings, Jr., M. D. presented the need for a study of a great number of petroleum products to determine their potential toxicity. This was reviewed extensively by the Operating Subcommittee. While most members were in sympathy with the idea, the general opinion was that nothing could be done unless there was a specific problem that had to be solved. B. National Poison Prevention Week J. W. Osborn, M. D., who has been appointed liaison with the National Poison Prevention Week Committee, asked the group how extensively the API should get into this program. The possibility of requesting the Committee on Public Affairs of the API to develop material for use by the petroleum companies was discussed. Chairman Schneider suggested that this be brought to the attention of the Medical Advisory Committee for their action. IX. ADJOURNMENT The meeting adjourned at 10:35 P* M. J. E. W0.. Hammond, Mattocks, Secretary Recorder Approved : R. F. Schneider, M. D., Chairman API 0775 > APPENDIX 3 REPORT OF THE SUBCOMMITTEE ON ATMOSPHERIC POLLUTANTS C. L. Samuelscr., M. D., Chairman April 6, The Subcommittee 1962. Six of the 10 or. Atmospheric Pollutants met on Friday morning, nine members were present. There were visitors. Subcommittee members gave various reports covering meetings with the Automotive Manufacturers Association, the Air Pollution Research Council meeting, the progress of the Lead-In-Air Committee Studies and a meeting with CRC Committee on Diesel Exhausts. Dr. Schneider; reported on a liaison meeting of certain members of the Medical Advisory Committee and the Air and Water Conservation Committee on the general subject of the effects of Air Pollution on Health. The meeting adjourned at 10:00 A. M. for a visit to the Shubik laboratories at the Chicago Medical School. While it is too soon to have any progress reports on the work which we are sponsoring, Dr. Shubik and associates showed us their facilities and some of the techniques being used in this study. The subcommittee reconvened at 1 :0 0 P. M. with 15 visitors present. Members and visitors expressed their views as to the possible ways and means of increasing the effectiveness of the subcommittee's work. At the closed session, the following items were discussed. Certain recommendations are presented for Medical Advisory Committee approval. I. ORGANIZATIONAL CHANGES The subcommittee feels that it should keep other API groups better advised as to its activities. The subcommittee also feels that in return, it should be better advised by other groups of the API as to their interests and activities in the field of air pollution where matters of health and physiology are concerned. To accomplish this, the subcommitted recommends: A. That the liaison now in existence with the Air and Water Conservation Committee be continued but that such liaison be strengthened by: (1) Having the chairman of the Research Advisory Committee of the Air and Water Conservation Committee be one of the liaison members of our subcommittee. (2) Having the chairman of the Research Advisory Air and Water Conservation Committee and/or other Conservation Committee liaison members inform the such activities of the Air and Water Conservation have to do with matters of physiology, health, or Committee of the Air and Water subcommittee of Committee that medical aspects. 3 . That liaison membership be established with whose activities might be of interest and benefit to those groups of the API which might be benefitted by committee other groups of the API the subcommittee, or with the activities of the sub C . Tr.at further organizational changes which might prove bene: :st interests cf the API be discussed with such liaison members as API 07752 2 3-2 D. That all groups cT the API be advised that the members of the subcommittee are willing to assist, if possible, in all matters having to do with health aspects -f air pollution. RESEARCH As a statement of policy, the subcommittee feels that, for the present, it shall concern itself primarily with the aspects of bronchiogenic carcinoma, pulmonary fibrosis and pulmonary emphysema as these might arise from petroleum products and th=ir use. With this in mind, coupled with recent reports, the subcommittee recommends: year 1 9 6 3 *A. That the work now underway with Dr. Shubik be continued during the B. That the subcommittee, through liaison meetings, acquaint themselves with such work having physiological or medical potentials or implications, now being carried out by other groups in the API. Such knowledge might give rise to new and further research work either by new undertakings or by broadening or projecting studies now underway. III. LITERATURE REVIEW The subcommittee has reservations as to the value received from money spent for literature review. The subcommittee feels that more value might be obtained from timely and detailed critical reviews of certain current articles, reports, studies, etc., which might have a bearing on the industry or its products. The subcommittee therefore recommends: A. That the literature review be carried out by the members of the subcommittee. B. That any current article having to do with the industry or its products be critically reviewed by the subcommittee as to accuracy, conclusions, and industry implications with the possibility of drafting a rebuttal and possible publication of same. C. That the subcommittee have the right to submit such articles to outside individuals or laboratories for independent critical analysis. IV. BUDGET The subcommittee presents the following budget for Medical Advisory Committee approval: A. $4 2 ,0 0 0 for the continuation of the Shubik studies for the year 1 9 6 3 * B. $5 ,0 0 0 , or that portion of it that may be spent by the subcommittee, for outside critical reviews, analysis and comments on certain articles, papers, ' reports, studies, etc. C. L. Samuelson, M. D., Chairman 1 ; j | j t J | j ' j I j J | ' ' i i < i API 07753 r APPENDIX ru REPORT OF THE SUBCOMMiTTEE ON C9 - C12 AROMATICS Kieffer Davis, M. D., Chairman The subcommittee met at 1 :0 0 P. M., Saturday, April 7 , 1962, at the Pick-Congress Hotel, Chicago, Illinois. Seventeen members and visitors were present. Dr. Carl Nau, chief investigator, summarized the work in general which had been completed under this subcommittee sponsorship and gave conclusions resulting from data accumulated. All present agreed that the work had been well done and that the findings are of such importance that Dr. Nau should publish a report of it in a reputable and proper journal. The Subcommittee on C9 - C12 Aromatics will continue to exist until such time that its members review the manuscript on this subject prepared by Dr. Nau for publication. Meeting adjourned at 2 :2 0 P. M. Kieffer Davis, M. D., Chairman 9 From minutes, meeting Committee - April , 1of9 6t2h,ePMiecdki-CcoanlgrAedsvsisory Hotel, Chicago, Illinois 1 API 07754 REPORT' OF THE SUBCOMMITTEE ON DERMATOLOGY J. Vf. Osborn, M. D., Chairman APPENDIX D 1:00 P. The subcommittee met at the M., Friday, April 6, 1962. Pick-Congress Hotel, Chicago, Illinois, at MEMBERS PRESENT: MEMBERS ABSENT: J. W. Osborn, M. D., Chairman C. H. Baylor, M. D. R. C. Burton, M. D. A. E. Dooley R. R. Dugan, M. D. F. D. Gassaway, M. D. B. S. Miller, M. D. H. B. Snyder, M. D. GUESTS PRESENT: A. E. Currier, M. D. H. Van Raalte, M. D. G. A. Sinclair, M. D. Peter Swan, M. D. James Ryan, M. D. F. H. Herrmann, M. D. R. E. Eckardt, M. D. R. E. F0.. Schneider, Mattocks M. D. Standard Oil Company of California Royal Dutch Shell, The Hague Imperial Oil Ltd. Esso Petroleum Co., Ltd., London Standard Oil Company of California Esso A. G., Germany Esso Research & Engineering Company Standard Oil Company (New Jersey) American Petroleum Institute LIAISON WITH DR. FLOYD VAN ATTA. RE: CUTTING OIL DERMATITIS This subcommittee will continue the liaison with Dr. Floyd Van Atta, Industrial Hygiene Engineer, United Automobile Workers, AFL-CIO, in conjunction with the Hygiene Panel, Lubrication Committee, API Division of Marketing, as soon as it can be determined who has succeeded M. D. Gjerde as chairman of the Hygiene Panel. Should the Hygiene Panel no longer be interested in joint liaison, the Subcommittee on Dermatology expects to keep in touch with Dr. Van Atta on the cutting oil dermatitis situation, which he first brought to our attention in i960. II. LIAISON WITH U. S. PUBLIC HEALTH SERVICE Through the subcommittee chairman's liaison in the area of dermatology with Dr. Donald Birmingham, Occupational Health Field Service, Public Health Service, Cincinnati, Ohio, we will attempt to obtain copies of "Report of Expert Panel of Dermatologists to Food and Drug Administration" for study by this subcommitnee and possible distribution or recommendations to the Medical Advisory Committee. J. W. Osborn, M. D., Chairman API 07755 r > APFENDIX 2 R5PCRT GF THS SUBCOMMITTEE CN INDUSTRIAL HYGIENE J. A. Sper.ce, Ph.I., Cr.airr.an The Subcommittee on Industrial Hygiene met on April 7 , 1 9 6 2 , with five mem bers and three guests present. Liaison members to the American Standards Association reported on the activ ities of the Z-62, Z-3U and Z- k Committees. Attached is the report on the activities cfthis Committee on Acceptable Concentrations of Toxic Dusts and Gases. It is anticipated the Subcommittee's project report on "industrial Hygiene Aspects of Petroleum Refining Processes" will be available to the Medical Advisory Committee by November 1962. On the Walsh-Healey Act, the National Safety Council is seeking considera tion for revision of the safety regulations required under defense contracts. The De partment of Labor has thus far given no indication of considering changes. The status of the Interdivisional Committee on Asphalt was reviewed. The Subcommittee members were asked to submit any pertinent information on environmental problems to the Asphalt Committee. In considering new business, several members expressed interest in labora tory fume hoods. Mr. N. V. Hendricks accepted the assignment to prepare a question- aire for distribution to the Subcommittee members. It is hoped this would give a pro file of the types of fume hoods used within the petroleum industry. This could be help ful to member companies seeking economic and effective protection for laboratory per sonnel. J. A. Spence, Fh.D., Chairman API 07756 I ) } Z 2 American Standards Association Z34 Committee on Acceptable Concentrations of Toxic Dusts and Cases ' Report to the A^I Ve'dical Advisory Committee April 9, 1962 ' On February 20, 1962, the United States placed its first astronaut into orbit. This day is also noteworthy because it marked the first meeting of this Committee since December 6, 1956. The status of each American Standard was reviewed during the meeting and plans made to expedite completion of the ones in the hands of various groups. Approved American Standards Carbon Monoxide Hydrogen Sulfide Carbon Disulfide Benzene Manganese Chromic Acid and Mercury Xylene Chromates Lead Toluene Oxides of Nitrogen Methanol Formaldehyde Carbon Tetrachloride Methyl Chloride Trichloroethylene p-Dichlorobenzene (in press) Standards Submitted to ASA for Approval Methyl Bromide Ethylene Dichloride Standards Submitted to Sponsor (AIHA) Nitrogen Dioxide Formaldehyde Trichloroethylene Tetrachloroethylene Methylene Chloride Chlorine Methyl Chloroform Styrene Monomer *Methyl Chloride Proposed Substances Assigned to Subcommittees Ethylene Oxide Propylene Oxide Propylene Glycol Methyl Ether Dipropylene Glycol Methyl Ether Cyclohexane Cyclohexanol Cyclohexanone Methylcyclohexane . Methylcyclohexdnol Methylcyclohexanone Nitroethane 2-Nitropropane Nitromethane Other Substances Discussed Cadmium Chromic Acid Silica Standard being revised Acetylene Tetra Diisocyanates Ozone Bromide API 07757 3-29-62 Allan E. Dooley> API Representative r ) APPENDIX F CF THE SUBCCMMUTZE V. ON C. 3MEDICAL POLICIES AI.D AIMirjSTHATIVE aird, M.D. , Chairman PRACTICES MEMBERS PRESENT: F. F- 3 oys, M.D. G. A. Sinclair, M.D. GUESTS: A. E. Currier, M.D. MEMBERS ABSENT: j V. C. Baird, M.D. T. J. Kelly, M.D. J. P. Malia, M.D. i j G. M. Saunders, M.D. 3\4 <1* I The subcommittee met on Friday, April 6th. No project was assigned to the Subcommittee on Medical Policies and Ad ministrative Practices during the year. ' Discussion was confined to two subjects. The first subject was a suggestion that members of medical departments of companies who are members of the Medical Ad visory Committee distribute to each other copies of policies, bulletins, and reports - that are suitable for professional distribution. The second subject was an inquiry j \ as to what means or methods are available to control unduly prolonged sickness ab- * sence that appears unwarranted. As only two members of the subcommittee were in attendance, no recommenda tion or. either subject is being made to the Medical Advisory Committee at present. G. A. Sinclair, M.D. i for V. C. Baird, M.D., Chairman i i i API 07758 1 ) APPENDIX G REPORT OF SUBCOMMITTEE ON PHYSICAL AGENTS G. H. Callings, Jr., M. D . , Chairman The Physical Agents Subcommittee met April 7 , 19&2 , with fcur members arc ten guests present. Reports were received from members assigned to cover recent developments ir. various areas of interest to the Subcommittee. Selected items of possible inter est to the MAC are as follows: 1. Considerable work is being done on development of instruments to quantitate worker's exposure to noise. Some of the devices are of miniature size and can be carried in the pocket of workers for hours at a time. 2 . Development of a standard for noise levels in California industry was reported to be nearing final phases. Unlike other state standards now in existance the Calif ornia standard will probably be more specific than just an over all sound pressure level. 3. Dr. Glorig's office has given a tentative opinion that the recently announced Otocups (Rudmose Associates) are not expected to be a satisfactory substitute for sound treated hearing testing booths for audiometric testing. U. A short review of the recent developments in the effects of vibration on health has been prepared by Dr. Kieffer Davis and a limited number of copies are available on request. The Subcommittee recommends that the MAC continue to support Dr. Glorig's work by a contribution of $2,500 next year. During the year the Subcommittee recommended to the petroleum industry adoption and use of the International Standards Organization Criteria for Noise. Copies of this standard were distrubted to MAC members. G. H. Collings, Jr., M. D., Chairman API 07759 ) ) APPKISIX H REPCRT ;? THE SUBCOMMITTEE CU SPECIALTY PETROLEUM PRODUCTS C. H. Baylor, M. D. , Chairman Present: Mr. Hammcr.d, Drs. Csbcrr., Stewart, Gerarde, Baylcr (Chm) Excused: Br. Henson, Mr. Cole. Retired: Mr. G. Er.twistle Visiters -Fifteen Minutes of last meeting were read and approved. Reports of clinical research on hydrocarbon ingestion: A. Dr. McKay (U. of Vt.) reported no cases because the number has dropped almost to zero due to publicity given such cases and public education in his area. B. Dr. Mintz (Baylor U. - Houston) reported 37 cases of whom one died and 36 recovered. The data were incomplete as submitted but this matter will be followed up and reported in full to the subcommittee and the Medical Advisory Committee. Due to contain technical problems and possible policy changes to be settled, the subcommittee plans to have a special meeting in New York City in May to which Drs. McKay and Mintz will be invited. In the meantime, the subcommittee members will have an opportunity'to study the long-awaited report of the 1co1o1p.)erwahtiicveh kerosine appeared study under the direction of Dr. Edward Press (Evanston, in the April 1962 issue of the Pediatrics. The subcom mittee discussed the possible use of gas chromatography for hydrocarbon an alyses and measurements but decided, for the present, that the time is not opportune for pursuit of this technique in its program. The subcommittee anticipates that the number of cases of hydrocarbon ingestion will decrease markedly in the next few years for two reasons: (l) the educa tion of the public to keep these materials out of tne reach of children and (2) the increasing number of state and federal labeling laws covering hazard ous substances. The subcommittee would like to recommend to the MAC that it and the API participate by whatever methods they see fit in any sound program of public education directed toward the prevention of poisoning. Some discussion concerned other specialty petroleum products that might, sooner or later, engage the interest and activity of the subcommittee. We wish to record a minute of appreciation for the long and faithful service to the subcommittee of Mr. George Entwistle who retired last year. The subcommittee requests r.o additional funds at the present time. C. H. Baylor, M. D., Chairman API 07760 ) > APPENDIX I r e p o r t c f i h b s u r c c v m i t t z z ::: t o x i c o l o g i c a l r e v i e w s H. W. Gerarde, M. D. , Chairman The subcommittee met at 3 P- M. on Saturday April 7 , in the Career Room cf the Pick-Congress Hotel. A number of visitors attended the meeting. Since the last meeting of the Medical Advisory Committee in November 1961, four Toxicological Reviews have been approved for publication by the sub committee. These are: Styrene, Cyclohexane, Sulfur Dioxide and Sulfuric Acid Mist. The next reviews to be circulated will be second drafts on Cumene and Kerosine and a first draft on Aromatic Petroleum Naphtha. This will complete the revision of the Toxicological Reviews on hydro carbons and hydrocarbon mixtures. Rather than revise old Toxicological Reviews on substances which have been adequately described in recent literature, the subcommittee will review, select and recommend a number of publications available on these materials which are suitable for use by the petroleum industry. This will make it possible for the subcommittee to devote more time to the preparation of reviews not available elsewhere on subjects of interest to the petroleum industry. An example of this is a review on gasoline which has been requested and for which there is a great need. I move adoption of this report. H. W. Gerarde, M. D., Chairman I ApP 07761 !4 1 > APPENDIX J t h e s u b c ::-"s t i e s : n mist inhalation V. Her.ricks, Chairman The first phase cf the subccmni tee work has been completed wirfc pub-icaticr. of "A Review cf Exposures -c Oil mist." This summarizes the best available information on this subjec from the literature, official agencies ar.d industry. The subcommittee continues to work closely with Dr. Stoklnger of the Public Health Service in his animal studies of oil mist inhalation. Three experimental oils, representing past and current market cutting oils, have been prepared and submitted for test. One of these oils is scheduled for study in June and another in September. Availability of exposure chambers will determine the rate at which studies are started. Dr. Stokinger's studies to date have been done with a white oil obtained from the open market, This oil was selected to establish a base line for future work. Experimental animals include dogs, rats, rabbits and 5*0 100 3 hamsters. These have been exposed at two levels, mg/m^ and mg/m 1 .0 with particle size controlled to micron. Exposures were six hours a day, six days a week for over a year. This has now been completed and no pulmonary response has been observed and no pathology has been seen on t,he lung sections. Tumor susceptible animals are now under study and the first of these should be ready for sacrifice by this time. As a final phase of our work we are now trying to arrange for an epidemiological study of a worker group with long exposure to oil mist. Con tact has been made at a number of locations and there is some interest in a study by Allis Chalmers Corp. This is to be developed, and if it does not materialize, every effort will be made to find some other suitable location. We expect that such a study will take money. Due to the broad interest in this area we feel justified in requesting a Public Health Service grant for the work. This will be our approach when satisfactory arrangements have been worked out for a study. If a grant cannot be secured, or if for some reason we do fore, wneorawrieshretqoueussteingthe$s1e0 ,0f0u0ndst,o then have other money would be needed. There available for this study. Approval of these funds is requested. N. V. Hendricks, Chairman API 07762 1 ) APPENDIX X REPORT CF THE IXTERDIVISICXAL COMMITTEE ON LABELING Allan E. Dooley, Chairman Representatives of the API Interdivisional Committee on Labeling have met with officials of the Food and Drug Administration four times since the last meeting of the Medical Advisory Committee. The first meeting which was held in December 1961 was a joint meeting with representatives of the Manufac turing Chemists Association, Chemical Specialties Manufacturers Association, and the National Paint, Varnish and Lacquer Association also present. Each 1 2 of the four associations made oral presentations amplifying their written com ments on the August , 1961 regulations. We believe that the presentations of the August 1four associations made in December contributed to the extension until , 1962 of the regulations concerning type sizes and labeling locations on containers. The other three meetings, the last of which was held- on April 5th, were concerned with clarification of the regulations regarding the labeling of petroleum distillates. The Committee representatives have submitted information on the aspiration hazard of petroleum distillates which was developed by Dr. Horace W. Gerarde of the Esso Research & Engineering Company and the Rutgers University Bureau of Biological Research. Dr. Gerarde's research which he kindly made available to the API Committee shows that the aspiration hazard of petro leum distillates is not a function of the amount of distillate present in a product. Rather, viscosity is the most important physical property. On the basis of Dr. Gerard's work, the API Labeling Committee has recommended to the FSDSAU/1tCh0at0 only those petroleum distillates with viscosities F. be considered as hazardous materials following of less than aspiration. +5 The FDA is now considering this recommendation. A special subcommittee with Mr. W. H. Barcus as Chairman has been considering the necessity of testing petroleum distillates to determine if they are skin irritants under the standards of the federal labeling regulations. This subcommittee has not arrived at a final decision but it appears that very little, if any, skin irritant tests will have to be made to answer this ques tion. Completion of the revision of the API Bulletin 2511 on Precautionary Labeling has been delayed pending action of the FDA on our recommendation re garding petroleum distillates. Allan E. Dooley, Chairman API 07763 r ) > 5P- PCRT CF LIAISON WITH SUAPAXTi:^ SERVICE TO 3 MEDICAL ADVI CKT COMMITTEE APPENDIX T Liaison with Epidemiology and Domestic Operations Branch, Division of Foreign Quarantine last report to the of the U. S. Public Health Medical Advisory Committee Sonervtihcee 1 h3atsh continued. Since the of November, 1961, there have been numerous communications from the Branch concerning, primarily, cholera, smallpox, yellow fever, influenza and the new International Certificates of Vaccination. Some of the information was felt to be of sufficient importance to the API members to pass on to the MAC. Some was not. Cholera In the previous report to the MAC, it was noted that there was a cholera-like disease cially recognized as 1 1 in Manila. Subsequent to that time the disease was cholera, and on December , 1961, the U. S. Public offi Health Service recommended that all persons be vaccinated against cholera and that per sons entering the United States within five days from an infected area would be required to present later report of the a valid certificate U. S. Public Health of vaccination against Service dated December 1c5hotlherian.dicAated that there were, unofficially, stated to be more than 2,000 cases and 300 deaths due to a cholera-like disease in the Philippines and that the disease appeared to be spreading. On December lUth, the U. S. Public Health Service issued a memorandum to "All Carriers - Air and Maritime" which reported the wide-spread occurrence of a cholera-like disease in the Biilippines and recommended certain precautions including vaccination. On the 8th of February, 1962, the U. S. 21 Public Health Service informed us that during the period of January through 2 February , there had been an outbreak of para-cholera in North Borneo with bo 15 cases and deaths and stated that the Public Health Service would require a 5valid certificate of days of departure. vaccination for On the 29th of 1 9 6 2 arrivals from that area to the U. S. within March, , we were informed that the epi demic in the Far East, which had not been well documented, had apparently subsided. At the present time only occasional cases of cholera-like disease are being re ported from that general area. No cases have been reported from Japan. Smallpox In December, 1961, we received information that the Congo was re quiring a valid smallpox vaccination certificate of anyone entering or leaving the city of Leopoldville. There has been an extensive outbreak of smallpox in Western Europe. The first case to be reported was from England where a man who had traveled from 28 Karachi and arrived in pox on December th. 1 9 6 2 London on December 25th had a confirmed diagnosis of small On January Uth, , we received a report from the U. S. Public Health Service of a case of smallpox in Germany. At that time, Germany had declared Dsseldorf an infected area. secondary cases, the initial case arriving 1 There had been one imported and two from Liberia on December st and be coming ill on December 15th. have been, Since until the the initial jth of 88 cases were reported from England March, 1962, a total of cases 17 and Germany, there with deaths re ported from England, Wales and Germany. England and Wales have reported 3 total 50 of cases with l b deaths, the most recent case occurring in the Cardiff area 1 9 in Wales during the week of March th. There were five initial cases, all being API 07764 2 L-2 33 interned fro:.. Karachi in Pakistan. Germany has reported a total of cases with 32 cr.ree deaths. There were five cases in Dsseldorf, cases in Mcnchaukreis and ore case of March 26ir. Aachen, the most recent case being reported in Monchaukreis the th. There were two initial cases in Germany, one being imported week from Liberia and the other from Bombay, India. Yellow Fever There have been occasional rumors of cases of yellow fever occurring outside the known endemic area. However, none of these has been verified and as of the 29th of March, 1962, the U. S. Public Health Service has no new intelli gence to report concerning the presence of yellow fever outside of the known endemic areas which are outlined in the booklet, "immunization Information for International Travel," U. S. Public Health Service Publication No. 38*+. Influenza On the 5th of March, 1962, the U. S. Public Health Service stated that influenza of the Asian strain was prevalent in Japan and parts of Eastern Europe and was reported from France. In addition, type B influenza was present in Eng land and in Poland and a further spread of both types was anticipated. On the 29th of March, 1962, the U. S. Public Health Service reported that the outbreak of influenza in Eastern Europe was subsiding, and only occasional cases had re cently been reported from Western Europe. International Certificates of Early in February, V1a9c6c2i,nathteionnew booklet-type of International Certif icates icates 19 2 of Vaccination was received and information about the new was sent to all members of the MAC on February 19, ^ . type of certif Prepared by G29eoMrgaercMh. 19S6a2unders, M. D. GMS:ar API 07765 ) } APPENDIX M p z p c r t o k l i a i s c n w i t h ::a h :i:a i p c :s c :; p r e v e n t i o n w e e k t o MEDICAL ADVISCRE COMMITTEE 1 . National Poison Prevention Week - 19o 2 The Congress of the United States passed a law in 1961 authorizing the president to proclaim a National Poison Prevention Week each year. On February 7 , 1962, President Kennedy issued a proclamation "directing" the appropriate agencies of the Federal Government and "inviting" state and local governments and organizations interested in child safety to participate actively in programs intended to promote better protection against accidental poisoning. He proclaimed the week beginning March l8, 1962, as National Poison Prevention Week. It is expected that the third week in March will be re-designated annually as National Poison Prevention Week. The organizational Public meetin Health Service, g in Washington Division of on November 2 1Accident , 1961, Prevention, called an to which the API was invited. Mr. Mattocks and Dr. Osborn attended this meeting at which time a National Steering Committee was organized. This committee agreed to focus on the prime tar get for 1962, "prevention of accidental poisoning among children under five." Mr. Henry L. Verhulst of the U. S. Public Health Service and Director of the National Clearing House for Poison Control Centers, was elected secretary of this Steer ing Committee for the 1962 Poison Prevention Week. This committee subsequently issued helpful information on ways to promote this national week. This material included sample posters, articles for the use of editors, suggested proclamations for mayors for city participation, a list of available material such as brochures, flyers, pamphlets, films, slide talks, addresses, an editor's fact sheet and radio and T.V. spot announcements. The effectiveness of the 1962 week will undoubtedly be analyzed in due time by the National Steering Committee. The API did not participate directly, per se, because there was insufficient time to seek the necessary approvals. How ever, the availability of the materials mentioned above was circulated by Mr. Mattocks' office to members and technical advisors of the MAC with the idea of encouraging individual companies to participate in this Poison Prevention Week Mianrcthheilr8-l2lo+c,al1 9a6n2d. regional areas of interest throughout the United States, 2 . National Poison Prevention Week - 1963 and subsequent years. At this time the Medical Advisory Committee should decide whether or not it wishes to recommend direct participation by the API in I963 and subsequent annual Poison Prevention Weeks. It would seem advisable to do so, especially from the public relations point of view as well as from the public health, pre ventive medicine and accident prevention point of view. The API, through the MAC, has actively supported reasonable legislation and regulations regarding the labeling of hazardous substances intended or suitable for household use. It would seem reasonable and logical that the API should continue to support educational efforts toward preventing a c c idental misu s e of the many products which get into the home, a number of which are petroleum products. API 07766 r> - 2 M- I recommend that the Medical Advisory Committee recommend to the general committee of the Division of Technical Services that active partici pation in National Poison Prevention Week for 1963 be discussed with the API Oil Information Committee and the API Accident Prevention Committee so that a decision may be reached no later than November 1962 at the time of the annual API meeting. J. W. Osborn, M. D.