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DORNE@efsa.europa.eu] 1/18/2018 1:48:06 PM Gwinn, Maureen [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=4bdc5237a5c440a7b664518e23eb5647-Gwinn, Maureen]; 'aoyagitomoko@nite.go.jp1; 'bahadori.tina@epa.gov'; 'barone.stan@epa.gov'; tara.barton-maclaren@canada.ca; 'bucher@niehs.nih.gov'; 'chang.daniel@epa.gov'; 'Jean-Lou.DORNE@efsa.europa.eu'; 'Flowers.lynn@epa.gov'; GISSI Andrea [Andrea.GISSI@echa.europa.eu]; 'gwinn.maureen@epa.gov'; 'Philippe.hubert@ineris.fr'; 'taiseni@hotmail.co.jp'; 'lsaacs.kristin@epa.gov'; 'kavlock.robert@epa.gov1; 'kenneth_lee@bmsi.a-star.edu.sg'; 'cleanair@snu.ac.kr'; 'Eeva.Leinala@oecd.org'; 'loolh@bii.a-star.edu.sg'; 'Lidka.Maslankiewicz@rivm.nl'; NETZEVA Tatiana [Tatiana.NETZEVA@echa.europa.eu]; 'kerry.nugent@nicnas.gov.au'; 'Orme-Zavaleta.Jennifer@epa.gov'; 'paul-friedman.katie@epa.gov'; RASENBERG Mike [Mike.RASENBERG@echa.europa.eu]; 'tomasz.sobanski@echa.europa.eu'; 'strope.cory@epa.gov'; 'thomas.russell@epa.gov'; 'Maurice.WHELAN@ec.europa.eu'; 'Zartarian.Valerie@epa.gov'; 'Lambert.jason@epa.gov'; 'Jones.samantha@epa.gov'; 'm.viant@bham.ac.uk1; KARAMERTZANIS Panagiotis [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=user7df58845]; 'beck.nancy@epa.gov'; 'Julien.CAUDEVILLE@ineris.fr'; KILIAN Karin [Karin.KILIAN@ec.europa.eu]; HUUSKONEN Hannele [Hannele.HUUSKONEN@echa.europa.eu]; ROSSI Laura [Laura.ROSSI@echa.europa.eu]; Markey, Kristan [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=a075536a33b247d393bl643f84ea5dfa-Markey, Kristan]; deborah.ratzlaff@canada.ca; 'john.prindiville@canada.ca'; 'Angelika Zidek' [angelika.zidek@canada.ca]; Scarano, Louis [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=298e8a818eb6426bb5731a202ablacl7-Scarano, Louis]; 'Jowitt Li' [jowittli@hotmail.com]; 'Steve Lin' [steve.lin@sahtech.org]; Ross, Mary [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=98359cdlf66f46ec91d327e99a3c6909-Ross, Mary]; Morris, Jeff [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=55c34872e6ea40cab78be910aec63321-Morris, Jeff]; Angrish, Michelle [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=98d337f83ea24740b8ae21da697aclel-Angrish, Mi]; Henry, Tala [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=8bfc0a617a4a43baa8856541c70622be-THENRY02]; Christine.norman@canada.ca; matthew.gagne@canada.ca; HANSEN Bjrn [Bjrn. HANSEN @ec.europa.eu]; MALM Jukka [Jukka.MALM@echa.europa.eu]; 'Andrea.TERRON@efsa.europa.eu'; 'Djien.Liem@efsa.europa.eu'; 'Bob.DIDERICH@oecd.org'; 'joli@sahtech.org1; 'hohojoong@hanmail.net'; 'KUNIHIKO_YAMAZAKI@env.go.jp'; 'jkanno@hh.iij4u.or.jp'; Lowit, Anna [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=ld3428a2c0b84d5099124a0460babd53-Anna B. Lowit]; Sappington, Keith [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=lc95ed87b01241a5addbe88fa4257f6c-Keith G Sappington]; Vandenberg, John [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=dcae2b98a04540fb8d099f9d4dead690-Vandenberg, John]; Deener, Kathleen [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=b9a2fflc086249ea8f6414afde8a5e54-Deener, Kathleen]; 'jose.tarazona@efsa.europa.eu'; 'warren.casey@nih.gov'; 'Chan Chun Yong, Eric' [phaccye@nus.edu.sg]; 'chuan_peiying@a-star.edu.sg'; 'horie-masashi@nite.go.jp'; 'chem6778@korea.kr'; 'ifanger@korea.kr'; 'yukyung@naver.com'; 'gardenhl@hotmail.com'; 'Babich, Michael' [MBabich@cpsc.gov]; 'Markey, ['Gina.Solomon@calepa.ca.gov']; 'Chuan_Peiying@bmsi.a-star.edu.sg'; 'sebastianms@bii.a-star.edu.sg'; 'nicole.davidson@canada.ca'; 'maya.berci@canada.ca'; Rodan, Bruce [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=Rodan, Bruce]; Scott, Elizabeth [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=52de4d2d6bc44938908ca2e010e9834a-Scott, Elizabeth]; Blair, Susanna [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=6c869b985f3d43db982cl8aaabd826bd-Blair, Susa]; 'Shaunalea Savard' [shaunalea.savard@canada.ca]; Mottley, Tanya [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=33a000296a364b0dad31fb9aaa34605d-Mottley, Tanya]; Frithsen, Jeff [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=e3743bd6f3c345baaae407cld6f78e92-FRITHSEN, JEFF]; Wambaugh, John [/o=ExchangeLabs/ou=Exchange Administrative Group Sierra Club v. EPA 18cv3472 NDCA Tier 12 ED 002061 00039292-00001 Subject: Attachments: (FYDIBOHF23SPDLT)/cn=Recipients/cn=e70988d0f51b4e28a4b2d20acfd0ccd2-Wambaugh, John]; Patlewicz, Grace [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=325clb8a80624ab08fb26fe9fbd4a55f-Tier, Grace]; 'nakamuraruriko@nite.go.jp1; Hanley, Mary [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=58e0d3d52d424d45ae88e4386ae4f8dd-Hanley, Mary]; cindy.woodland@canada.ca; sarah.Iabib@canada.ca [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=497a7a27414f4bl68439b6b95cc8ec65-sarah.labib]; ktkim@seoultech.ac.kr; Guiseppi-Elie, Annette [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=63d3e2eaeb9c4acba2609baa90b0f735-Guiseppi-EI]; Beck, Nancy [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=168ecb5184ac44de95a913297f353745-Beck, Nancy]; Orme-Zavaleta, Jennifer [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=3c5allldc377411595e5b24b5d96146b-Orme-Zavaleta, Jennifer]; maurice.whelan@ec,europa,eu [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=0500clc3152c4910b7dbca54d6dl3d4d-maurice.whelan@ec.europa.eu]; Zartarian, Valerie [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=81096fe8dd024bdf935dec292bf44f9d-Zartarian, Valerie]; Solomon, Gina@EPA [Gina.Solomon@calepa.ca.gov]; aoyagi-tomoko@nite.go.jp; Bahadori, Tina [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=7da7967dcafb4c5bbc39c666fee31ec3-Bahadori, Tina]; LIEM Djien [Djien.LIEM@efsa.europa.eu]; Lit-Hsin Loo (Bll) [loolh@bii.a-star.edu.sg]; Lambert, Jason [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=d2254c2fb9504e9088b2b935492b8aaf-Lambert, Jason]; Davidson, Nicole (EC) [nicole.davidson@canada.ca]; Jagla, Magdalena (EC) [magdalena.jagla@canada.ca]; Kathleen.Vork@oehha.ca.gov; Flowers, Lynn [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=la4411c874d041b9a8badfc32b91bd70-Flowers, Lynn]; Thomas, Russell [/o=ExchangeLabs/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Recipients/cn=12fll9e7a3ee447499f3d6ab5d20daeb-Thomas, Rus]; Eeva.LEINALA@oecd.org; HUBERT Philippe [Philippe.Hubert@ineris.fr]; CAUDEVILLE Julien [Julien.CAUDEVILLE@ineris.fr]; ROBINSON Tobin [Tobin.ROBINSON@efsa.europa.eu] RE: Accelerating the Pace of Chemical Risk Assessment teleconference TKPIate.docx Dear All, A new case study w e w ould like to launch under ACPRA: TKplate as an open source TK m odelling platform. The project was briefly presented at the Helsinki meeting. W e are now making the big jum p inviting you to join and seeking your support. Best Regards JL Dr Jean Lou Dome Senior Scientific Officer-Toxicologist Scientific Committee and Emerging Risks Unit Department of Risk Assessment and Scientific Assistance CumjstM Sifsly Ayltefsty Via Carlo Magno 1A 43126 Parma (Italy) Tel. +39 0521 036 472 www.efsa.europa.eu Sierra Club v. EPA 18cv3472 NDCA Tier 12 ED 002061 00039292-00002 tw itter.com /EFSA EU voutube.com/EFSAchannel This e-mail, including its attachments, is intended only for the use of the recipient(s) named above. Unless you are a named recipient (or authorised by a recipient), access to this e-mail message or any disclosure or copying of its content, or any action taken in reliance on it is unauthorised and may be unlawful. If you are not the intended recipient, please let the sender know immediately. From: Gwinn, Maureen [mailto:gwinn.maureen@epa.gov] Sent: 20 December 2017 15:07 To: 'aoyagi-tomoko@nite.go.jp'; 'bahadori.tina@epa.gov'; 'barone.stan@epa.gov'; tara.barton-maclaren@canada.ca; 'bucher@niehs.nih.gov'; 'chang.daniel@epa.gov'; 'Jean-Lou.DORNE@efsa.europa.eu'; 'Flowers.lynn@epa.gov'; GISSI Andrea; 'gwinn.maureen@epa.gov'; 'Philippe.hubert@ineris.fr'; 'taiseni@hotmail.co.jp'; 'Isaacs.kristin@epa.gov'; 'kavlock.robert@epa.gov'; 'kennethjee@bmsi.a-star.edu.sg'; 'cleanair@snu.ac.kr'; 'Eeva.Leinala@oecd.org'; loolh@bii.astar.edu.sg'; 'Lidka.Maslankiewicz@rivm.nl'; NETZEVA Tatiana; 'kerry.nugent@nicnas.gov.au'; 'OrmeZavaleta.Jennifer@epa.gov'; 'paul-friedman.katie@epa.gov'; RASENBERG Mike; 'tomasz.sobanski@echa.europa.eu'; 'strope.cory@epa.gov'; 'thomas.russell@epa.gov'; 'Maurice.WHELAN@ec.europa.eu'; 'Zartarian.Valerie@epa.gov'; 'Lambert.jason@epa.gov'; Jones.samantha@epa.gov'; 'm.viant@bham.ac.uk'; KARAMERTZANIS Panagiotis; 'beck.nancy@epa.gov'; Julien.CAUDEVILLE@ineris.fr'; KILIAN Karin; HUUSKONEN Hannele; ROSSI Laura; Markey, Kristan; deborah.ratzlaff@canada.ca; 'john.prindiville@canada.ca'; 'Angelika Zidek'; Scarano, Louis; 'Jowitt Li'; 'Steve Lin'; Ross, Mary; Morris, Jeff; Angrish, Michelle; Henry, Tala; Christine.norman@canada.ca; matthew.gagne@canada.ca; HANSEN Bjorn; MALM Jukka; 'Andrea.TERRON@efsa.europa.eu'; 'Djien.Liem@efsa.europa.eu'; 'Bob.DIDERICH @oecd.org'; 'joli@sahtech.org'; 'hohojoong@hanmail.net'; 'KUNIHIKO_YAMAZAKI@env.go.jp'; 'jkanno@hh.iij4u.or.jp'; Lowit, Anna; Sappington, Keith; Vandenberg, John; Deener, Kathleen; 'jose.tarazona@efsa.europa.eu'; 'warren.casey@nih.gov'; 'Chan Chun Yong, Eric'; 'chuan_peiying@a-star.edu.sg'; 'horiemasashi@nite.go.jp'; 'chem6778@korea.kr'; 'ifanger@korea.kr'; 'yukyung@naver.com'; 'gardenhl@hotmail.com'; 'Babich, Michael'; 'Markey,; 'Chuan_Peiying@bmsi.a-star.edu.sg';'sebastianms@bii.a-star.edu.sg'; 'nicole.davidson@canada.ca'; 'maya.berci@canada.ca'; Rodan, Bruce; Scott, Elizabeth; Blair, Susanna; 'Shaunalea Savard'; Mottley, Tanya; Frithsen, Jeff; Wambaugh, John; Patlewicz, Grace; 'nakamura-ruriko@nite.go.jp'; Hanley, Mary; cindy.woodland@canada.ca; sarah.Iabib@canada.ca; ktkim@seoultech.ac.kr; Guiseppi-Elie, Annette; Beck, Nancy; Orme-Zavaleta, Jennifer; WHELAN Maurice; Zartarian, Valerie; Solomon, Gina@EPA; aoyagi-tomoko@nite.go.jp; Bahadori, Tina; DORNE Jean-Lou; LIEM Djien; Lit-Hsin Loo (BII); Lambert, Jason; Davidson, Nicole (EC); Jagla, Magdalena (EC); Kathleen.Vork@oehha.ca.gov; Flowers, Lynn; Thomas, Russell; Eeva.LEINALA@oecd.org; HUBERT Philippe; CAUDEVILLE Julien Subject: Accelerating the Pace of Chemical Risk Assessment teleconference Dear all, Thank you again for the productive meeting in Helsinki. As you recall, we asked for updated abstracts on the case studies by December 8, 2017. If you have not already, please send us your update as soon as possible and I will share with all prior to our teleconference. Please note the new call-in information listed on the agenda. As a reminder, materials from the October workshop can be found at -- - ] January 18, 2018 APCRA Teleconference Agenda Conference call numbei Ex. 6 1. Follow-up from October 2017 workshop a. General Feedback i. Specific feedback on workshop b. Action items from the workshop i. Update on case studies (case study leads) 1. Activity since the workshop Sierra Club v. EPA 18cv3472 NDCA Tier 12 ED 002061 00039292-00003 2. Current status 3. Timeline to completion ii. Update on communication on use of NAMs 1. Scope of activity iii. Outreach about APCRA activities (Please share any outreach activities with Maureen Gwinn at Kwinn.m aureen@ epa.gov) 1. Overview presentation at OECD IATA Case study meeting (November 2017; slides in share drive) 2. Draft commentary submitted to journal (ECHA, ERA, HC) 3. Society of Toxicology (March 2018) a. Poster presentation on workshop overview (ECHA, EPA, HC) b. Platform presentation on case study #3 (EPA) c. Others attending/presenting at Society of Toxicology meeting in March? 2. Other topics? For the topic on outreach on the agenda, please share any outreach activities with Maureen Gwinn at gwinn.m aureen@ ep3.gov if you'd like them included in the notes. Also, for your information, I am sharing a link to a recently released ECHA report that might be of interest to you. The report is on the regulatory applicability of non-animal approaches under the three EU chemicals regulations coordinated by ECHA (REACH, CLP and BPR). http s://w w w .e ch 3 .europa.e u /-/m o re -p rog ress-n e ed e d-to-rep la ce-an im al-te sts-u n de r-e u -ch e m ica ls-l3w s Thank you, Maureen Maureen R. Gwinn, PhD DABT ATS Senior Science Advisor National Center for Computational Toxicology Office of Research and Development 1200 Pennsylvania Ave NW MC8101R Washington, DC 20460 t(202)564-4621 10021565=24311___ I Ex. 6 i Sierra Club v. EPA 18cv3472 NDCA Tier 12 ED 002061 00039292-00004