Document 65wprwdOnzV0k6NyVz8eygR0m

SXfg&XSEHUL WORE ~ SAR&SAC XABORATCBY grinding Dust Exposure on laboratory Animals December 24, 1946 Vr I* Dunn* Treasurer *ew York Office Enclosed herewith is a report covering the first 10 soothe of our experimental work which Dr* Gardner wae doing for us at Saraaao Lake* You will note that in mih of the groups of animals exposed to duet ora* an 8 to 10 month period, the findings as far as production of fibrosis In the lungs is concerned, are essentially negative* In other words the experiment thus far warrants a tentative conclusion that the &st exposure in our grinding operations while producing changes observed In'the x-ray fils is a relatively Inert dust* This substantiates ^ original impression that the nodulations we have seen are not due to true silicosis but are similar to the changes observed In lungs of "persons exposed to iron dust* It is of course too soon to draw any definite oenoluslons but the implications are very encouraging and very satisfying to me After we have had a ohanoe to observe the results, over the next period of months I feel that we will be in a position to definite!^ state that we ere not dealing with silicosis but a non-disabling aiderosis. . You will also note Paragraph 4 which so far indicates that theanimela whioh_J; have been Infected with tuberculosis and than dusted shew no appreciable dlfforesee In other words the spread of infection it apparently not accelerated by the initiation of this dust during the 8 months' period study* 2 feel that we should consider the money spent in this experimental work to be a very definite contribution to our knowledge of dust diseases and one that I think will have far reaching effects not only as far as Brake 8ho# is ooncerned but through the industrial world in general* I think that you and Hr* Given and others; concerned in making this experimental work possible deserve a great deal of credit for war foresight and cooperation in making this study possible* When theexperimentsiwork has been completed, 1 plan to write it up In detail and publish the story* This will not be, of course, for some months yet "ta&.nothing will be published without your approval* I will let you know as soon as we have any more results* lH<np Enclosure L* B* Hamlin, HD Medical Director SPNY 000434