Document 65BZmnLxX2Qd1dO353KEBKO8o
3M General Offices
AR226-1895
3M Center St. Paul. MM 55144-1000 651 733 1110
September 24, 20(53, 52"' 27
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By Hand Delivery
Document Processing Center (7407) Office of Pollution, Prevention and Toxics U.S. Environmental Protection Agency 1200 Pennsylvania Avenue, N. W. Washington, DC 20460 Attention: Section 8(e) Coordinator
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Re: TSCA Section 8(e) Submissions
Dear Sir/Madam:
3M Company ("3M") requests that EPA place the attached studies in the TSCA Section 8(e) docket. We have included a master index for these studies identifying the study title, test substance and CAS number. A Confidential Business Information (CBI) version of this index and the studies also is being submitted today pursuant to EPA procedures. 3M has not provided CBI substantiation with this submission, but would be willing to do so at the Agency's request.
3M has concluded that data in these studies may not be, strictly speaking, "corroborative" of previously reported or published information as defined in EPA's reporting guidance or otherwise potentially may warrant 8(e) submission based on EPA's reporting guidance.
3M appreciates EPA's attention to this matter. Please contact the undersigned if you have any questions or require further information regarding this submission.
Very truly yours,
Q -04 - 1 584 7
88040000366/S
Dr. Katherine E. Reed, Ph.D
cC..j. -tr-
c::>
Staff Vice President
o
Environmental Technology and Safety
Services
(651)778-4331 kereed@mmm.com
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Master Index to Studies Submitted Under TSCA 8(e) by 3M Company on September 24, 2004 (Confidential Business Information Redacted)
Prim ary E ye Irritation S tudy -
R abbits
1 I I ______________________________________ 1 2 0 % solids (E thom een S /1 2 1.0M w ith diethyl
su lfate 0 .9 4M ); 80% w ater (Ethom een S /1 2 = R -
G uin ea Pig C ontact D erm al Irritation/S ensitization
N (E t)+ (C 2 H 4 0 H )2 w h ere R = C 1 8 w ith 1 -2 d ouble bonds)
20% (6 1 7 9 1 -2 4 -0 w ith 6 4 -6 7 -5 ); 80% 7 7 3 2 -1 8 -5
Prim ary E ye Irritation S tu dy -
R abbits
B utanoic a d d , heptafluoro-, calcium salt
2 3 6 6 -9 8 -5
A cute O ral Toxicity S creen w ith T 2712C o C in A lbino R abbits
perfluorohexanoic acid
3 0 7 -2 4 -4
Prim ary S kin Irritation T e s t w ith T -
2 7 2 5E c (R e p e a t A pplication) in
A lbino R abbits
[
A cute O cular Irritation T e s t w ith T -
I[
]
2 7 2 5 E c in A lbino R abbits S ensitization S tudy w ith T -2 7 4 1 A C
[
1[
1
in A lbino G uin ea Pigs
[
) ........ t
O ra l R angefinder S tudy o f T -3 1 4 0 B S 1 -(3 '-(p erfluo ro octanesulfon ate) anilino am id e]-2
I
in Pregnant R ats
potassium 3 ,4 ,5 ,6-tetrachlo ro ph th aiate
5 7 5 8 9 -8 5 -2
8 0 % 1-[3'-(p erfluo ro octanesu lfo nate) anilino
am id e]-2-p otassiu m 3 ,4 ,5 ,6 -
O ral R angefinder S tudy o f T -3 1 3 9 B S tetrachlorophthalate; 5% C 7 hom olog; 5% C 5 80% 5 7 5 8 9 -8 5 -2 ; 5 % 6 8 5 4 1 -0 1 -5 ; 5% 6 8 5 4 1 -0 2 -6 ;
in P regnant R ats
hom olog; 5% C 4 hom olog; 5% C 6 hom olog
5% 68568-54-7; 5% 6 8 8 1 5 -7 2 -5
A cute O ccular Irritation T e s t w ith T - perfluoroethylcyclohexylsulfonic acid diethanol
2997C o C in A lbino R abbits
am in e salt
salt o f 1 3 3 2 0 1 -0 7 -7 and 1 1 1 -4 2 -2
S en sitizatio n S tu dy w ith T -3 3 8 6 in
A lbino G uinea Pigs
[
In V itro M icrobiological M utagen icity
][
1
A ssays o f 3M C om pany's
Compound T -3 4 1 1
[
] I ______________________________________ 1
v1
Master Index to Studies Submitted Under TSCA 8(e) by 3M Company on September 24, 2004 (Confidential Business Information Redacted)
6 8 % p o ly(o xy-1,2-eth an ed iyl), alp h a-[2-
(ethyl[(heptanedecafluorooctyl)sulfonyt]am ino]et
hyl]-om ega-hydroxy-; 12% polethylene glycol;
7 % w ater; 4 .8 6 % p oly(o xy-1,2-eth an ediyl),
alp h a-{2-
[ethyl[(pentadecafluoroheptyl)sulfonyl]am inojeth
ylj-om ega-hydroxy-; 4 % residual organic
fluorochem ical; 3% hep tad ecaflu oro-1-
octanesulfonic acid; 0 .8 1 % poly(o xy-1,2-
eth an ed iyl), a lp h a-[2-
[ethyl[(undecafluoropentyl)sulfonyl]am ino)ethyl)-
om ega-hydroxy-; 0 .3 % 1,4-d ioxane; 0 .2 % n -
68% 29117 -0 8 -6 ; 12% 25322-68-3; 7% 7732-18-5;
ethylperfluorooctanesulfonam idoethyl alcohol; 4 .8 6 % 5 6 3 7 2 -2 3 -7 ; 4 .0 5 % 6 8 2 9 8 -7 9 -3 ; 3 .2 4 %
A cute O ra l Toxicity S creen w ith T - 0 .0 3 % lin ear n-ethyl
6 8 2 9 8 -8 1 -7 ; 3% 1 7 6 3-2 3 -1 ; 0 .8 1% 6 8 2 98 -8 0 -6 ;
3 4 4 8 in A lbino R ats
perfluorooctanesulfonam ide
0 .3 % 1 2 3 -9 1 -1; 0 .2 % 1 6 9 1-9 9 -2 ; 0 .0 3 % 4 1 5 1 -5 0 -2
In V itro M icrobiological M utagen icity
A ssays o f 3M C om pany's
Com pound T -3516
[
A cute D erm al T oxicity S tudy w ith T -
]t
1
3451 in A lbino R abbits
C 8 F 1 7 S 0 2 N (C H 3 ).N a
Unknown
A cute O ral T oxicity - M ethod,
Sum m ary, Pathology; P rim ary
D erm al Irritation - M ethod.
Sum m ary; P rim ary E ye Irritation -
M ethod, Sum m ary; G u in ea Pig
M axim ization - M ethod, Sum m ary A cute O ral T oxicity - M ethod,
I
1l
_J
Sum m ary, Pathology; P rim ary
D erm al Irritation - M ethod,
Sum m ary; P rim ary E ye Irritation -
M ethod, Sum m ary;
[
]f
J
D erm al S en sitizatio n S tudy in
t
l[
1
G uin ea Pigs, M axim ization T es t -
M ethod, Sum m ary
t
II
.]
4 H our A cute A erosol Inhalation
I
I[
............
Toxicity S tudy w ith T -3 8 2 5 in R ats P rim ary E ye Irritaiton/C orrosion
I
1i
1
S tudy in R abbits 4 -H o u r A cu te A erosol Inhalation
f
1 t ...
I
Toxicity S tudy w ith T -3 8 2 5 in R ats t
1[
1
2
Master Index to Studies Submitted Under TSCA 8(e) by 3M Company on September 24, 2004 (Confidential Business Information Redacted)
T -3 8 2 0 : A cute Inhalation Toxicity Test T -3 8 2 1 : A cute Inhalation Toxicity Test T -3 8 4 5 A cute Inhalation Toxicity Test E valuation o f the A cute Inhalation Toxicity o f T -3 9 2 0 in th e R at P rim ary E ye Irritation S tudy in R abbits - M ethod, Sum m ary A cute O ral T oxicity S tu dy in R ats (O E C D G uid elin es) A cute Inhalation T oxicity S tu dy w ith T -4 1 2 9 in the R at A cute Inhalation T oxicity S tu dy with T -4 1 3 0 in th e R at A cute O ral Toxicity S tudy in R ats; A cute D erm al Irritation S tudy in R abbits; A cute E ye Irritation Study in R abbits D erm al S en sitizatio n Study in G uinea Pigs - M axim ization T es t
[_____________ ________________________ 1______ [
[ heptafluorobutyryl chloride
1[ 3 7 5 -1 6 -6
Il D ecano ic a d d , nonadecafluoro-, am m onium
s a lt 9 5 % am m onium perfluorodecanoate; 5% am m onium perfluorooctanoate
I 3 1 0 8-4 2 -7 5% 3825-26-1
[ 1I l ]l
[ 1[ l 1[
.
1 1
]
l ]
] 1
M utagenicity T e s t on T - 4 4 1 3 [ J
M ou se Lym phom a Forw ard M utation
A ssay w ith D u plicate C ultures
[
A cute Inhalation T oxicity S tu dy w ith
][
1
T -4 3 5 4 in the R at
I______________________________________ 1
P rim ary D erm al Irritation/C orrosion
[
1
Study in R abbits A cute Inhalation Toxicity S tudy in
i ______________________________________ 1
[
1
the R at w ith T -4 3 9 7 Prim ary E ye Irritation /C orro sion
i
.... 1 t
1
Study o f T -5 2 6 1 in R abbits
lithium tetrafluo ro eth ane-1,2-d isu lfo nim ide
Unknown
A cute Inhalation T oxicity E valuation
on T -5 2 3 1 in R ats 4-H o u r, A cute Inhalation Toxicity
i ______________________________________ l ........ [
>
S tudy w ith T -5 3 0 5 in R ats 4-H o u r, A cute Inhalation Toxicity
I ______________________________________ ) ............. [
I
S tu d y (L im itT e s t)w ith T -5 3 4 3 .1 in
R ats
i
1 i ______________________________________ 1
3
Master Index to Studies Submitted Under TSCA 8(e) by 3M Company on September 24, 2004 (Confidential Business Information Redacted)
i ., 4-H o u r, A cute Inh alatio n Toxicity
I
'"ty' ii ,
..'-M
: 1
{' 1,', ?"
Study W ith T -5 3 0 6 in R ats 4-H o u r, A cute Inhalation Toxicity
[
I[
3
S tudy (Lim it T e s t) w ith T -5 3 5 7 .1 A cute D erm al T o xicity S tudy o f T -
[
I[
3
4201 in R abbits
Lithium B is(T rifluorom ethanesulfonyl)im ide
9 0 0 76 -6 5 -6
S ubA cute 2 8 -D a y O ra l Toxicity w ith
T -2 8 1 6 by D aily G avag e in the R at
Follow ed by a 14 D ay R ecovery
P e rio d
t
S u bacu te 2 8 -D a y O ra l T oxicity with
1 t ._
3
T -2 8 1 6 by D aily G a v ag e in th e R at
Follow ed by a 1 4 -D a y R ecovery
P e rio d
[
A cute Inhalation T oxicity Evaluation
1l
3
on T -5 1 8 7 in R ats
t
T -4 2 4 0 4 -W e e k O ra l T oxicity Study
][
3
in R ats D erm al S en sitizatio n S tu dy o f T -
l
] [ .....
3
5 4 7 3 in G u in ea Pigs - M axim ization
Test 4-H o u r, A cute Inh alatio n Toxicity
I
][
3
Study W ith T -5 6 9 8 in R ats
l
A cute Inhalation T o xicity Evaluation
It
3
O n T -5 7 0 8 in R ats T -5 4 8 6 A ssessm ent o f C ard iac
[
]i
1
S en sitizatio n P o ten tial in Dogs
o c ta flu o ro p ro p a n e
7 6 -1 9 -7
A cute Inhalation Toxicity Evaluation
on T -5 6 5 5 in R ats
[
T -4201 4 W e e k O ral T oxicity S tudy
3t
3
in R ats w ith 2 -W e e k R ecovery
P eriod
Lithium B is(T rifluorom ethanesulfonyl)im ide
9 0 0 76 -6 5 -6
T -5 6 5 8 : E ve Irritatio n to th e R abbit t A cute Inhalation Toxicity E valuation
1l
3
on T -5 7 1 5 in R ats
I
A cute Inh alatio n Toxicity E valuation
3[
1
o n T -5 7 1 6 in R ats
1
A cute Inh alatio n Toxicity S tudy o f T -
3I
1
5 7 2 4 in R ats
[
A cute Inhalation Toxicity Study o f T -
3[
3
5 7 2 5 (R e sin S o lu tio n ) in R ats
I ______________________________________ 3_______ 1_________________________;_____________ 3
]
4
Master Index to Studies Submitted Under TSCA 8(e) by 3M Company on September 24, 2004 (Confidential Business Information Redacted)
A cute Inhalation Toxicity Study
(Lim it T e s t) o f T -5 9 2 7 in R ats
1
A cute Inhalation Toxicity S tu dy o f T -
5 9 2 8 in R ats (L C 5 0 )
l
A cute Inhalation Toxicity Evaluation
on T -5 8 2 9 in R ats S in g le-D o se Intravenous
t
Pharm acokinetic S tudy o f T -5 9 6 3 in
R abbits S in gle-D ose Intravenous
[
Pharm acokinetic S tudy o f T -6 0 3 0 in
R abbits
I
.
]l 1L JI
I L ........
lI
] l l
1
]
8 7 -9 3 % fluorinated alkyl alkoxylates; 4-1 0 %
linear N -eth yl perfluorooctanesulfonam ide; 2 -
4% p o ty(o xy-1,2-eth an ed iyl),.alp h a.-[2-
[ethyl[(pentadecafluoroheptyl)sulfonyl]am ino]eth
yl]-.om ega.-m ethoxy-; 0 -4 % residual organic
fluorochem icals; 0 -2 % c 8 sulfonam ide; 0 .1 -1 %
5-D aily D ose D erm al
1-heptanesulfonam ide, N -eth yl-
A bsorption/Toxicity Study o f T -6 0 2 9 1 ,1 ,2 ,2 ,3 ,3 ,4 ,4 ,5 .5 .6 ,6 ,7 ,7 ,7 -p e n ta d e c a flu o ro -; 8 7 -9 3 % 6 8 9 5 8 -6 1 -2 ; 4 -1 0 % 4 1 5 1 -5 0 -2 ; 2 -4 %
and T -6 0 3 2 in R abbits
m iscellaneous com ponents (ea c h less than 1% ) 6 8 9 5 6 -6 0 -1 ; 0 -2 % 3 1 5 0 6 -3 2 -8 ; 0 .1 -1 % 6 8 9 5 7 -6 2 -0
S in gle-D ose Intravenous
Pharm acokinetic Study o f T -6061 in
R abbits S in gle-D ose Intravenous
t
l[
1
Pharm acokinetic Study o f T -6 0 6 5 in
R abbits S in g le D ose Intravenous
[
lt
1
Pharm acokinetic S tu dy o f T -6 0 6 3 in
R abbits
[
A cute Inhalation Toxicity Study o f T -
Il
1
6 2 3 5 in R ats
t
Prim ary D erm al Irritation/C orrosion
1t
1
S tudy o f T -6 4 0 2 in R abbits
t
1t
]
D erm al S en sitizatio n Study o f T -
6402 in G uinea P igs- M axim ization
T est (E C G uid elin es)
[
]
A cute E ye Irritation/C orrosion Study 1-B utanesulfinic acid, 1 ,1 ,2 .2 ,3 ,3 ,4 ,4 ,4 -
w ith T -6 3 1 8 in th e R abbit
nonafluoro-. Sodium S alt
[ 1 0 2 0 6 1 -8 2 -5
I
5
Master Index to Studies Submitted Under TSCA 8(e) by 3M Company on September 24, 2004 (Confidential Business information Redacted)
Prim ary Skin Irritation / Corrosion
Study w ith T -6 5 6 7 in th e R abbit (4 -
H our S em i-O cclusive A pplication) Assessm ent o f C ontact
[
]
H ypersenitivity to T -6 3 1 8 in the
A lbino G uinea Pig (M axim ization
1-B utanesulfinic acid, 1 ,1 ,2 ,2 ,3 ,3 ,4 ,4 ,4 -
T e s t)
nonafluoro-, Sodium S alt
S in gle-D ose Intravenous
Pharm acokinetic S tudy o f T -6 5 0 2 in
R a b b its S in gle-D ose Intravenous
t
1
Pharm acokinetic S tudy o f T -6 5 0 4 in
R a b b its S ingle D o se Intravenous
t
J
Pharm acokinetic S tu dy o f T -6 5 0 6 in
R a b b its A Study for E ffect on Em bryofoetal D evelopm ent o f th e R at (In h alatio n A dm inistration)
1'
1
2 0 -8 0 % m ethyl nonafluoroisobutyl ether; 2 0 80% m ethyl nonfluorobutylether
B acterial R everse M utation T es t o f T
6695 5-d a y Inhalation Toxicity o f Perfluorocyclohexene ([ ]; T 6 8 7 8 ) in R ats
[1
70% crude perfluorocyclohexene; 30% p eriluorom ethylcyclopentene
5-D aily D ose D erm al
A bsorption/Toxicity S tudy o f T -6 5 0 2
and T -6 5 0 3 in R abbits Prim ary E ye Irritation/C orrosion Study o f T -6 7 8 6 in R abbits
[1 Lithium B is(perfluoroethylsulfonyl)im ide
Prim ary D erm al Irritation/C orrosion
Study o f T -6 8 0 4 in R abbits
Lithium B is(perfluoroethylsulfonyl)im ide
5 -D ay Inhalation T oxicity S creen of
HFEt 1
C -C 6F110C H 3
Prim ary E ye Irritation/C orrosion
Study o f T -6 8 0 4 in a R abbit (O E C D
G uidelines)
Lithium B is(perfluoroethylsulfonyl)im ide
A cute O ral Toxicity S tudy o f T -6 8 0 4
in R ats (O E C D G u id elin es)
Lithium B is(perfluoroethylsulfonyl)im ide
D erm al S en sitizatio n S tudy o f T 6 9 0 8 in G uin ea P ig s, M azim ization T es t (E C G uid elin es)
[l
1 0 2 0 6 1 -8 2 -5
[1 fI [ ]. 2 0 -80% 163702-08-7; 2 0 -80% 1 6 3 702-07-6 I ______________________________________ 1 70% 3 5 5 -7 5 -9
[ 1 3 2 8 4 3 -4 4 -8 1 3 2 8 4 3 -4 4 -8 4 9 4 3 -0 8 -2
1 3 2 8 4 3 -4 4 -8 1 3 2 8 4 3 -4 4 -8
I
6
Master Index to Studies Submitted Under TSCA 8(e) by 3M Company on September 24, 2004 (Confidentit Business Information Redacted)
E ye Irritation/C orrosion S tudy o f T 4 1 2 7 in the R abbit S in g le-D o se Intravenous Pharm acokinetic S tudy o f T -6 9 2 4 in R a b b its
N -M e Fos A m ide-Triphenylbenzyl Phosphonium
C hloride Com plex; D -1 62 4
3 1 5 0 6 -3 2 -8
I I[
D erm al S en sitizatio n S tu dy o f T 6 9 2 4 in G uinea P igs- M axim ization T est (E C G uid elin es)
[
............ 1
t
D erm al S en sitizatio n S tu dy o f T -
7 003 in G uinea Pigs - M axim ization
T es t (E C G uid elin es)
[
R eport o f S era and Liver D a ta for [ N -eth yl hep tad ecaflu oro-N [2-
1I
] M on oester - P relim inary A D M E
(phosphonooxy)ethyl) octanesulfonam ide
Study in R ats
diam m onium salt
6 7 9 6 9 -6 9 -1
l ) D iester-P harm acokin etic
Study in R ats (S tu d y N o . T -7 0 4 3 .1 , am m onium
D T -26)
bisfethyt(perfluorooctane)suifonayi]phosphate 3 0 3 8 1 -9 8 -7
S ingle D ose Intravenous
Pharm acokinetic Study w ith T -7 0 8 2
in Rabbits
[ N -eth yl h eptadecafluoro-N [2-
il
[ ] M onoester - Pharm acokinetic (phosphonooxy)ethyl] octanesulfonam ide
Study in R ats (S tu d y N o. T -6 9 9 7 .2 ) diam m onium salt
6 7 9 6 9 -6 9 -1
D eterm ination o f P F O S P resen ce
and C oncentration in S erum from
the D erm al A bsorption S tudies o f T -
7 1 0 6 and T -7 1 0 7 in H ra:(N Z W )S P F
R abbits D erm al S en sitizatio n S tudy o f T -
[
.1 [
7 2 8 5 .5 in G u in ea P ig s -
M axim ization T e s t (E P A /O E C D
G uidelines) T w en ty-eigh t D ay R ep eated -D o se
[
]I
O ra l T oxicity S tu dy o f T -6 8 6 1 in
R ats
Lithium B is(perfluoroethylsulfonyl)im ide
1 3 2 8 4 3 -4 4 -8
T w enty-eight D ay R epeated D ose
O ral T oxicity S tudy o f T -7 0 0 5 in
R ats
I ______________________________________ 1_______ t
I I 1
1
1 1 ........J
7
Master Index to Studies Submitted Under TSCA 8{e) by 3M Company on September 24, 2004 (Confidential Business Information Redacted)
1:
......... : :
,.i
f.......... ............................................................... --... - '?---- ------
A cute (4 -H o u r) Inhalation Toxicity o f
T es t A tm ospheres O btained a fter
H ealin g [
] in R ats I ..................................... . . .
Toxicokinetic S tudy o f
I
P erflurooctanesulfonam idoacetate ([
1; T -7 0 7 1 .2 ) in R ats
perfluorooctanesulfonam ido carboxylic acid
[ 2 8 0 6 -2 4 -8
]
A cute N o se-O nly Inhalation Toxicity
Study o f T -7 0 8 7 , T -7 0 8 8 . T -7 0 8 9
and T -7 0 9 0 in R ats (Lim it T est)
[
][
A cute O cular Irritation Study o f T -
(
.......... . .
3[
7 4 8 5 A pplied to N e w Z ealan d W h ite
R abbits
potassium nonafluorobutanesulfonate
2 9 4 2 0 -4 9 -3
T oxicokinetic S tudy o f
Perfluorooctane Sulfonam ide
(P F O S A ; T -7 1 3 2 .2 ) in R ats
periluorooctanesulfonam ide
7 54-91-6
A cute F our-H our Inhalation S tu dy in Perflurobutanesulfonyl Fluoride (9 6 -9 8 % ) And
R ats
Perfluorosulfolane (2 -4 % )
96-98% 3 7 5 -7 2 -4; 2-4 % 4 2 0 6 0 -6 4 -0
P rim ary E ye Irritation/C orrosion
S tu dy o f T -7 5 0 8 .2 in R abbits M V 31 K -S alz; T e s t for P rim ary
i
1[
D erm al Irritation in the R abbit
i
A ssessm ent o f A cute O ral Toxicity
] I .........................................................
w ith T -7 5 6 0 In T h e R at (A cu te Toxic
C lass M ethod)
i
A cute E ye Irritation/C orrosion Study
J............ [
..........
w ith T -7 5 6 0 in th e R abbit
[
1
l ...
.
[ J P otassium bis-
{periluorobutanesulfonyl)im ide
R epeat D o se A D M E Study in R ats Potassium bis(perfluorobutanesulfonyl)im ide 129135-87-1
Toxicity S tudy by R ep eat D o se
Inhalation A dm inistration to C D R ats Perflurobutanesulfonyl Fluoride (9 6 -9 8 % ) And
fo r 4 W eeks
Perfluorosulfolane (2 -4 % )
96-98% 3 7 5 -7 2 -4; 2-4% 4 2 0 6 0 -6 4 -0
] I
] 1 I 1
A S ub-acute{ 2 8 D a y ) Inhalation
Toxicity S tudy, Including a R ecovery 1 ,1 ,1 ,2,2.4,5,5,5-n o n aflu o ro -4-(triflu o ro m eth yl)-3
S tudy, w ith .T -7 4 7 9 in R ats
p e n ta n o n
7 5 6 -1 3 -8
X enochem ical R eceptor trans-
A ctivation by Perfluorooctane-based
C hem icals
;perfluorooctanesulfonam ide
7 5 4 -9 1 -6
8
Master Index to Studies Submitted Under TSCA 8(e) by 3M Company on September 24, 2004 (Confidential Business Information Redacted)
84% 1-o ctan esulfon icacid ,
1 .1 ,2 ,2 ,3 ,3 ,4 ,4 ,5 ,5 ,6 ,6 ,7 ,7 ,8 ,8 ,8 -
heptadecafluoro-, potassium salt; 5 .5 %
potassium (perfluorohexyl)sulfonate; 4%
potassium nonafluorobutanesulfonate; 4%
potassium perfluoroheptanesulfonate; 2%
potassium perfluoropentanesulfanate; 0 .5 %
84% 2 7 9 5 -3 9 -3 ; 5.5 % 3 8 7 1 -9 9 -6 ; 4% 2 9 4 20 -4 9 -3 ;
unknown
4% 6 0 2 70-55-5; 2% 3872-25-1
95% N -eth ylperflu oroo ctanesu lfo nam ido eth yl
alcohol; 5 % 1-heptanesulfonam ide N -eth yl-
1 ,1 ,2 ,2 ,3 ,3 ,4 ,4 ,5 ,5 ,6 ,6 ,7 ,7 ,7 -p e n ta d e c a flu o ro -N -
(2 -h y d ro x y e th y t)-
95% 1691-99-2; 5% 6 8 5 55 -7 3 -7
A cute Inhalation T oxicokinetic Study
o f Perfluoroctanesulfonyl Fluroide
(P O S F ) T -7 0 9 8 .4
perfluorooctanesulfonyl fluoride
3 07-35-7
F ive-D ay Inhalation Toxicity S tudy of
H F E [ 1 in M a le C D R ats
C -C 6F 11-C F 2-0-C H 3
1 8 1 2 1 4 -6 7 -5
A cute Toxicity S creen of
P erflu orocyd oh exen e (T -6 8 7 8 ) in 70% crude perfluorocydohexene; 30%
R ats
perfluorom ethylcydopentene
70% 35 5 -7 5 -9
[ ] (T -7056)
Toxicokinetic S tudy in R ats
f ................
_
..
1t
N -M ethyl P erfluorobutylsulfonam ide = 95% 1-
J
A ssessm ent o f A cute O ral Toxicity B utanesulfonam ide, 1 ,1 ,2 ,2 ,3 ,3 ,4 ,4 ,4 -
w ith T -7 6 0 1 .3 in the R at (A cute
N onafluoro-n-M ethyl; 5% N -M ethyl-4-H yd rid o-
Toxic C lass M ethod)
Perfluorobutylsulfonam ide
6 8 2 9 8 -1 2 -4
Subchronic 9 0 -D a y O ral Toxicity
S tudy w ith T -7 3 2 0 B y D aily G avag e
in the R at Follow ed by a 2 8 -D a y
R ecovery Period
1
1I
]
84% 1-octanesulfonic a d d ,
Protein Binding o f Perfluorobutane 1 ,1 .2 ,2 ,3 ,3 ,4 ,4 ,5 ,5 ,6 ,6 ,7 ,7 .8 ,8 ,8 -
S ulfonate, Perfluorohexane
heptadecafluoro-, potassium salt; 5 .5 %
S ulfonate, P erfluorooctane Sulfonate potassium (perfluorohexyl)sulfonate; 4%
and P erfluoraoctanoate to Plasm a potassium nonafluorobutanesulfonate; 4 %
(H um an, R at, and M onkey), and
potassium perfluoroheptanesulfonate; 2%
Various H um an-D erived P lasm a
potassium perfluoropentanesulfanate; 0 .5 %
Protein Fractions
unknown
potassium nonafluorobutanesulfonate
potassium (perfluorohexyl)sulfonate
84% 2 7 9 5-3 9 -3 ; 5 .5 % 3 8 7 1 -9 9 -6 ; 4% 2 9 4 20 -4 9 -3 ; 4% 6 0 2 70-55-5; 2% 3872-25-1 2 9 4 2 0 -4 9 -3 3 8 7 1 -9 9 -6
9
Master Index to Studies Submitted Under TSCA 8(e) by 3M Company on September 24, 2004 (Confidential Business Information Redacted)
potassium periluorooctanoate
F ive D ay Inhalation Toxicity Study of
{ ] M onochloride, [ J, and
H C F C 225cb in M ale C D R ats
C 4F9-O C H 2C I
C -C 6F 11-C F 2-0-C H 3
C F 2C IC F 2C H C IF
Toxicokinetic S creen of [
] (T -
7 4 8 3 ) in R ats
C 7 F 1 5 C (0 )N (H )C H 3
8 4 % 1-o d an esu lfo n ic acid,
1,1,2 ,2 ,3 ,3 ,4 ,4 ,5 ,5 ,6 ,6 ,7 ,7 ,8 ,8 ,8 -
h eptadecafluoro-. potassium salt; 5 .5 %
potassium (periluorohexyi)sulfonate; 4%
Low Level O ral
potassium nonafluorobutanesuifonate; 4%
P erfluorooctanesulfonate (P F O S ) potassium perfluoroheptanesulfonale; 2%
D o se Toxicokinetic S tudy in R ats: Serum and Liver P F O S
potassium perfiuoropentanesutfanate; 0 .5 % unknown
2 3 9 5 -0 0 -8 2 0 5 3 6 7 -4 2 -6 (n -iso m er) and 2 2 1 6 1 7 -8 6 -3 (1isom er) 1 8 1 2 1 4 -6 7 -5 5 0 7 -5 5 -1 8 9 6 8 5 -5 6 -3
84% 2 7 9 5 -3 9 -3 ; 5 .5 % 3 8 7 1 -9 9 -6 ; 4% 2 9 4 2 0 -4 9 -3 ; 4% 60 2 70 -5 5 -5 ; 2% 3872-25-1
10
