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Argus Research Laboratories. Inc. 905 Sheehy Drive, Building A Horshan. PA 19044 Telephone: (215) 443-8710 Telefax:(215) 443-8587 REPORT AMENDMENT I 12 OCTOBER 2000 PROTOCOL 4 18-009 COMBINED ORAL (GAVAGE)FERTILITY, DEVELOPMENTAL AND PERMATALPOSTNATAL REPRODUCTION TOXICITY STUDY OF N-ETFOSE M RATS FINAL REPORT Attached is the corrected Text Figure 1 to the above-referenced final report. This change reflects the addition of a notation for the dosage administration of the F1 generation rats and did not affect the results of the study. Associate Director of uesearch and Study Director L) Manager of Regulatory Compliance 4 18-009:PAGE 1-4 t REVISED PAGE t rn c U a z w rn gz*LL 0 0 a % > t 0 Y z ? 0 a 0 0 E W a A s U 2 Ir- n 2 2 zI<- a W E 0 2 < BA< I- zs I w z*-0 t d c a wLL s 6 Q < > < J < a 0 b0 Y z m 0 90 m t 6 0 0 c 0 a n. P x $; : 110 j= ' : .. .. B d I-