Document 5b9KZgpJM91X3Dg6D38n54K0N

2CJ Paul Penignus-10 October as, 1999 Wilbur Ipeloher Ablntrtntflf, Industrial Stygian* Weetlnghoua* IUtri Corporation Met Pittsburgh, Pennsylvania /oh far reur latlar of October 21 inquiring about ttu oof um of trlahltrodlphanyl and a alxture of *00 triohl 600 hasaehlorodiphaayl tlan of ti itfrlaohhlloorrooddllBphhoo^nlrland' " ~ The diphenyl The eeablnala loom InatlOB ia our ~ tte phyalaal and ahorlaal proportion of tho Areolar* Motioned are Aeon on the table on pages A and 5 f Aha onaloaod Areolar bulletla, fcelooed ala* la a reprint InrtljaMng the roaulta of ohfonla~toBlalty atudloa with Aroolon^fAc' end 125*. Bm folleoind ooMoeta or airing your questions serially are baaed on Information oontalnod in theao bullotlna. I boiler* prolonged and repeated akin eontaet with any of the Areelor* should be aroldod for too roaoona. Za the flret flaee, the loaa ohlorlnatod products are liquids and are eneelont aolventa for alia and fata la the akin aa well aa other onanle eaterlala. gaannrtly. it la poaalble that prolaraeil or repeated alda eontaet eould lead to ohloratwo, Z knar of only too ease* ehoro auoh oaporlonoo haa daralopad during the long Motory of probation and uae of the Arosloro. Zn ana ease, aa Araalor aa being uaod aa a boat tranafor asdime la a ayotM that oil dm I report to aaoapo ehM tho Mtarlal oaa boatad to by an laduatrlal phyalolan but deh la hla oarda oore aa latgnlflaant that fee aan oero not aaaro of than nor --uld a gonoral pcootltlonor notie* then, fhla Inileatet te mm, heorrer. 6BRN 000002 TOWOLDMONOOQ2593 I. tfllbtf flpeleher--Page 2--October 23, 1959 that sufficient exposure, idiether by inhalation of vapors or ittn contest, can result in ohloraonc milch Z think we oust assises could be an indication of aero carious systemic injury if the exposure was allseed to continue. . A second case of olid ehloraene about which ea have any' loiewledge resulted from worioMn dipping their hands In the liquid Arcelor aa if it were alncrml oil or vegetable oil. In addition, their clothing sooner or later became impregnated with the material and thus exposure was magnified. You asked at idiat temperature local exhaust ventilation should be provided. Although the distillation range for Aroelor 1242 is 325-360C. and 3fl5-420C. for Aroelor 1260, I feel that good practice dictates that looal exhaust ventilation be provided idten any of the Aroelora are heated above 150p. in open tanks or in any systems tdiere the material le not in a completely enclosed system (vapor-proof tanka, kettles, pumps, piping, etc.}. Ihls may be ultra conservative because as the distil lation ranges sad vapor pressure curves (pegs 12 of the Aroelor bulletin) indicate, the loss of vapors at 150F. should not bo significant exoept in any work area whore general ventilation or air changes do not exist. Your next question related again to possible sldn and aystamia sffeota and Z bellavo it la answered above. In sonnectlon with the 40Jf trlehlorobensene-600 Aroelor 1260 sombinstlon, Z believe the thoughts expressed above also apply. Z understand that tha trichlorobcnacnc which is used la a clxturt of the 1,2,3~ 1,2,4-, and 1,3,5-iacmcra which will begin to distill at 205C. Again, Z believe this Indicates a low vapor prsasura for tha solvent at room temperatures. Die only reference we have to trlchlcrobenscoe toxicity la con tained in the Public Health Servlet Publication No. 414 entitled "Die Halogsnated Hydrocarbons Taxlelty end Potential Dsngere" by Star. W. F. ven Osttlngen, U.8. Oovsrrmant Printing Office, 1955 (peace 297*296). fir. vein Oettlngem refers to some work dene 111 1937 Pilch indicated that the triehlorobensene waa less toxic than mono or dichlorobensenc. Zn my opinion, a reasonable HA6 for this material would be 100 parts par million. The enclosed publication on the toxicity of Aroolor 1242 and 1294 suggests an MAC for 1242 of 2 milligrams per eubie meter which Is twice that rsecmmsnded by the ACQZH for a shlorinated di phenyl of unstated chlorine eontent. Zn the ease of 1294, the publieation suggests that the MAO of 1 milligren per eubie meter "reconsaded tentatively for safe Industrial practice br the American Conference of governmental industrial Hygienists is reasonable. On the other hand, reference te Henry Myth's Cwlnge Mmerlal lecture of 1936 in which he llisneeed the beats for the then existing 'hygienic standards" indicates that 6BRN 000003 TOWOLDMONOOQ2594 ). I. v&ibur 3~ostabar S3, 1999 ______ that M6 of 1 ag/su.a. fav Aroalar IMS 0.3 j9u.a far Atmlav 129* gm asn NiliitU. a ........ # w ahrinla laUlti date as Areolar 1260, wl _ u MO f 0.5 ag/ou.a., Ih im m lath* on of 125*. ttm aatarlala wars uaod for __ ___ _________________ w aad tbo itllatloa am not la aoaoHlante with Tha only roperMd difficulty aa gnatloa ooblasts Mors tho - __ mad vapors of trlablaa iota tta vgrivMi Smb ttw ooblast . suab oablaats Mali bo vootUatod to ----------------------M ba ralaaaod lato um Z bar* boon tali that pour aaapaogr haa had aoaa -23 years* axpsrlaosa MM tba pnAata dlssusssd above. Xfc aaa auicnM that Mr* Maas b Pari* aaaaaor of tranoforwor anufasturlag ariglnaarlna at your Sara flaat would bo a aauras of laferaatlan mmlci axporionoo with Xoortoon ffO. Uallolr, Mr. X. X* Morburr of your Bloaalagtan, Indiana Float haa boon aaaoslatsd MM tbs uaa of Aroolev 12*2. favhapa you bars al ready dlaanaasd potential exposures with thoao genii--\, it aa, I would bo latavaatad la laaantng of tholv paaatlaal ox* porlanoo MM Maaa sawdusts. Z look forward to aoalas you la Pittsburgh next wood. Ilaaoroly, 6BRN 000004 TOWOLDMONOOQ2595