Document 5LwvzBnjR2p6DXYG7gMnDVVZ4

THE SCHOOL OF MEDICINE DEPARTMENT OF ANATOMY THE UNIVERSITY OF NORTH AT CHAPEL HILL 27515 CAROLINA februarv 5> , i?65 Jr. lobert l. Tehoe 'diversity of T'ncinnati Department o ' ^'"eventive .-iedic :r.e and industrial wealth '\5tt9r: t i^ Laboratorv college of ''ed'c'ne - ?.den Avenue Cincinnati 1, Jhio Dear Doctor Tshoe: Thank y>v for y ur letter of "'sbruarv 1 relative to the effects of `nhalinr r-asollne -;mes. It tells re nan;' things I wanted to knew and also raises crestions. T have turned uo in the literature some articles on the subject: Tolan and linrl (Am. J. Ps .'c'-- a try, 120:7g7) ~i *e graphic descriptions of the hallv.s; nations nroduced ;n two teen-age bovs; and fas son iPediatr5 cs 2?:2oO) reports the addiction ^n,children. raker's' Clin-'cal devrology describes both acute and chronic gasol"ne ooison'ng symptoms, and oermits ` .he distinction between th/Cs end? lead poisoning, as you do. But wha^ precisely in the7gasoline does one damage to the IDS and ow? Has enough autopsy data accumulated to indicate the center and fiber tracts of the brain which are affected? ..hat is the mechanism, of damage, e.g., desi,ruction of myelin, or the neurons themselves? If different brands ?f gasoline contain, different additives, knowledge of wrier, ones cause '.-/'rat lesions co- id provide a clue to relative toxicit-' of the -- anv nartic".lar age, sex, racial, cultural, or so'cio-econdm.ic mono? 7s.)rther reTerences to the sutfect, especially with regaru oo the neu rooatholcgy, w^uld be most welcTed. Thank voy amain for your interest and heir. ViIlian S, Pollitzer