Document 5LebodLzMxQ5oVnr7GkKR2088
am
E. I. pu Pont DE NEMOURS & COMPANY
Panxer5s.s0wU.iRnGBo,noaxW.12V1a7. 26101
POLYMER PRODUCTS DEPARTMENT
PERSONAL AND CONFIDENTIAL
"226-1607
CC: J. H. Todd
3 Sy JGR..L
TJ.. F.
BRuorsgeenrlund Doughty
G. H. Stoltz
R. N. Taylor
P. Thistleton
December 1, 1981
J. W. Raines Polymer Products Department Wilmington - M 5625
C-8 BLOOD LEVELS IN FEMALES TRANSFERRED OUT OF THE TEFLON DIVISIONS
The attached Table contains C-8 in blood data on eighteen females transferred out of the TEFLON Divisions at Washington Works around April 1, 1981, The following observations can be made:
ores 1 ap vrei devmr trend i vind 5
levels. This trend is statistically significant at 0.05 level using the paired-t test.
. aBlvoeordageC-8129l-edvaeyls pedrrioopdp.ed an average 15% over an
.
Rate of C-8 elimination varies greatly by individual.
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EID080677
'
C-8 BLOOD LEVELS IN FEMALES TRANSFERRED OUT OF TEFLON
aE L-E8AVILNEGVELTEWFHLEONNS
2 0.140
27
0.192
27 0.570
3 1.300
2
0.110
27 0.110
21
0.078"
37 2.400
27 5.100
23
0.061"
29 0.270
a 0.190
2
0.005"
2 0.450
27
0.230
2
0.092"
3
0.019
2 2.500
CL-E8AVILNEGVELTEAFFLTOENR 0.086 0.120 0.39 0.980 0.086 0.081
0.065
2.000 4.400
0.083
0.240 0.170 0.061 0.410 0.210
0.092
0.019 2.600
NBEUTMMBEEERNOFSAVDPALYESS 143 127 140 126 128 133
1487
139 126
128
130 127
9% 127 127
126-
133a
AVERAGE = 129 days
C-%8 CBHLAONOGDELEIVNELS -38.6 3.5 31.6 24.6 21.8 17.3
16.77
"16.7 13.7
-13.17
11 10.5 - 8.97 -8.9 - 87
0.0
0.0" +40
SigA Tg
15.3 1 11.7%
* The downward trend is statistically significant at 0.05 level using the paired-t test.
1205/41/81
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|
EIDOS0678
:
00163
so
`oe
Tlechnical- Engineers ond Chemists
1.) Teflon Polymers
SSSR Wuenker OF. Continuous
be
aly mer Techaical Work
Sed
S70
72k
10%
1583
ans
31st 11
BenSEER Humigr OF Continunus
TeRor workdaysSmmedidaly
1205
Tes
0
1096
7244
Je Su COT Gu Gem
35 0M
EI
[8M
50 0M
48 0M
to 0M
49M 56 0M
0.400
0.063
0.8/0
0.077
6.330
0. "oo
0.530 0.190
Range. 1 0.063 5 .0.530 ppm:
2.) TeflonCopolymers
Mean: 0.R75 ppm
EID080679
1
aoo
468 788
153
770
asa
198
o
az 0M <o.007
o
32 Mm
o.0HL
a3 wm
6.190
3 0M 6.180
o
a6 mM
0.400
o
ad M
6.210
47 Mm
0.480
o
do M
0.02 E
Rang. + <0.007i 0.480 ppm | Means 6.192 ppm
000164
Fine Powder Dispersion
1.) TeRe TEE Linris Operator. Jnie Quoden ~ DJroyenreOp)AMOoprsetruaretoChresck-eri,ngSpuumspes0p,
Bape
oe,Fire Coreder
Numberof Continuous.
NumberOFContinuons
a EoeRaaE Age
Sex C-% Tn Blood (pom)
67
73 95 1a
124
192
ads
317 437
S60
Gor bo3
738
871 Jobs
7303
o
3s
F
6.200
o
31
M
0.760
a5
M
0.6/0
o
38%
mM
0.610
as "
0.650
0
45
M
3.600
92
Ho
F
0.630
o
a
M
/. 100
as
TMM
4. 100
3a
F
2.100
o
51
F
1.500
o
"Ho
F
4.000
o
Hy
F
4.800
34
F
3.500
:
o
34
F
1.700
5
so Mm 2.900 :
Gangs 1.0.800 Zi 4.800 ppm
Mean: 2.047 pein [stent
= Ron. of oceania
2.) fo n re Ghouso SpnJaoiteQo uoinn. = (Zone & Operators
~ indudes Adoclave Opersiors and Dispersion Processor)s
-
000165
[EID080680
EE EER Biosa Sample. Collected Gporsteors Fine Fawder: Age Sex QF In Blood (orm)
M2
(ud 158
azo
Hes
cot
lo 70
nis
waa
Is83
7%
saat 6361 6410
6706 8510
8218
1536 wa
o
393
1887
1035"
547
547
790
R93]
EYEY) 21/30 436
2313 1216
48
M
2
M
29 M
3o
TMM
38
TMM
36
TMM
3 TMM
3
M
44 TMM
"44 M
43
M
m
47 TM
52 TM
62 TM kM
0.760
7. as0 $600
0-340
4. 200
4. 900
32.000
0. 20
4. 100
9.400
Q. soo
7. boo 70. 600 R44. 000
21. 600 29. 000
(Range i 0.220232pp. m 0 eo0 ns0 LER ppm
000166
:
EID080681
1) Talon omen Operon
foNLiuamokbevesernBdiOntfdeCSiaotmnbptealitensgGoouRses FNumeoebeLrio OftYCeorrRb:idmuIoours.E pge Sex Cof Tn Belo)
a4a
510
563
690
693
513
1206
1550"
2006 asoH
605
6358
7357"
n,a21*
1388
517
178
8340
S540
?
798
315
3591
les
3346
1338
153
So M
a8
M
a 0M
51
M
45m
3 mM
HSM
He TMM
58 0M
39 M
47 wm
54M
5 mM
585M
0.760
0.40
3.300
&.a00
7.200
0.4306
t.400
0.7/0
0.350
0.520
0.220
0.780
o. 100
o.640 Z
Clonge 10,100 25 8.300 ppm:
Hean Lo D.3F ppm
8
"C-8_accumdatin. Nutr (Buse omtymn Srclatsi poists:) = 0.08ppm yea
.
000167
9b. Hoschiamn
njsfes
EID080682
Lorton
I TPE dovie Opiate. Shonelor
NGruamnbulearrWOorftdaCyosntBienfuoerse NurirEgroOpFagCyodntimniudgluest
Vabrst BloodSample Collected EER Age
Sex C-8Tn Bland(opm)
3
517
100
loa
ne 123 126
do
2ag
768 \os0
1391
1418 A003
67
o
0
0 319
[4
0
4570
0
0 0
30
M
3
M
31
M
as M
as
M
a5
M
29
M
A
M
31
M
EY F
39
M
36
M
31
M
35 M
0.034
0. 340
0. /a0
0.052
0.076
0.027 0.920
0.038
0.8/0
6.810 4.800
KR. 600
. 930 /.a00
Carge 6. 084 4..4.500 ppm deans _0800_ppm
Gos of Amerease tO. 29_ppm- years.
z 2
.
000168
[EID080683
Lharwtar
2) IFE Grosse:Operats. Shandon
GNurmobmeerrOFWorCkoanatyisnuSoeufso.re.
rast Elat Sangte Collected
TNenumbeWroOkFiCdooynsTtmimneuieatsaly
SES
Age.
Sex C-2In Bioed (em)
533%
1263
[027
2837
282%
238%
2918
3903
asso"
Ho7
2983
350!
5905 3078
3346
5390
"
45 0M
39
M
39
M
"49
M
50 M
37 "
42 TMM
5%
M
55 0m
o.150
.500
3.000
4.500
1.900 7. 100
$000
6.670
3. 000
Otengeo- 0.150 15.9.100 ppm Means. 3.347 ppm.
Clee 7 C-8. accumtotion.C(fased 29:55 2 = 0.1Peppm/year
B
00019
EID080684
.
Tafto Mechanis
1. MechanicTallon
Nymbee OF Continuous Number OFCordinuons
pope
134
o
35 ~
0.059
4a
2
40 M
0.150
1548
7
43 M
6.320
ay
0
37 M
0.049
1636"
722
38
M
0.170
1792
0
44
M
0.650
220
4442
16 "
0.630
23717
0
50
"
0.200"
3042
?
39 "
0.790
201
1
38 M
0.170
3a44
?
39
M
0.520
2512
?
3%
M
0.630
2704
o
42
Mm
0.a50
495
0
33 M
6.780
4234
yas
Jeg
"4700
6195
65
3 2)
/.200
41 M
6.900
o
3% M
0.600
o
44 M
0.840
6
42 mM
0.750
LL?
o
cuir EIDOSOSES
F351
?
Gorges 0.049 45 1.200 ppm
Hs M
0. 09a Z
47m
0.170
57 M
020 8
Mean: 0:483 ppm
000170
.
nase
d-) Taft Maurdinance LepunrieaiLon
Nxumber OFcarpe CSounpteinruvoiussion Nanbeg Fond 0Mor8aga ContTinruoiusni
Gira Eos Age Sex Cf nGlood (ppm)
asa
1312 486o
o
39 M
0.270
o
55 mM
0.080
2
SE M
0.190
2) Taften Roductint Spnvision.. ~Choduction Jonemen_
BRIERE Humbe OF Continuous
reflon> Pr
n Foreman
BREET Af Se 09 Stet (pom) Nurober OF Continuous
Tel1on WorkelaysTmme diaksly
465 513
1295 1809
2448
2889 5967
4ooa 1778
o 34ot
o
Hid 1
31/8
21
~M
qi
M
95 M
37 Mm
54 M
sa
M
Ss
MM
a.400 0.490
J. ao0 0.810
/.100
0.850
0.960
(lenge : 0.460 5 R.400 ppm... Mean: 1.049 ppms
.
000171
Zz 2
g
EIDO080686
.
Hjotes
-
Stperviain, Cont`el -
a.) Taften Puoductens. Sponri =Soa pervin sion. Qhrove Joraman
TMouFlboeruOpFgyCionnRtioneuofuusran Neloun mberWoOrFkdCaoongtTirnmueoauisch
TEER BESEINEE
cer Cofin Silom
.
85
208
239,
ab Mm
0.120
2)
27 0M
0.634
o
a5 0M
6.140
5
.
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EID080687
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am
.
1.)
EEP
Sevvice
OpersiorF--ECZonCeopAolOypmerearksors:tetFinish,Oivneng, Phckauk, Shredder;andDisp
tia A hoe
Sirdardin YT
Sex.
C8 Tn Blood (ppm)
gn
43 21
mM
124
39
M
126
0 43
F
129
Be 35
F
135
0
a
M
R320
125
35
M
395
as
M
S11
23
M
132
o
a9
F
181
o
25
M
0.096
0.300
0.078
/.6o0*
0.653
/.860
6.170
0.540
/.a50 0.6/0
Glarge T 0.096 A /.tooppm ean: 0.589 ppm
*This Spacerspt cvinedyeano wiv other Teptenaruac fafouc
24) Cle, Fee Oparatin, -- Zone & Opersiors : Polykettle ana Extruder Operators
Ness Code
FakestBiednetsiened Age
Sex
2 -% Tn Bleedleem)
loa qd 5s
M
170% 1 ap
M
EYA vEl yg
M
ziqd EE so
M
9.600 **
4.206 2.700 4.000
3408 2011 43
M
3993 65 yy
M
1.300
300
z
Haad ams 49
Ade 3B (3
5778 wl 5 7
5902 5 gy
M
/.@00
M
7.800 g
M EDososss
M-
57 800
7.900
000173
angesL200 469.400 ppm Wear: 4.300 ppm
* KX ThiLs Sraity,apt sont paras am otha Teflon ana Qefoce
EEP_ Supervision
SNFuaimPkcpbeerrWaorkodf SSulmfores
Age
Sex C-8Tn Blood (oom)
Sid
21
TMM
bis
Hy
M
t3a
Hq
TMM
1708
Sb
M
480M firm opuetse1)
M
Sos!
52
TMM
0.048
6.047 0.150
0.330
2.100
0.5/0
(Rana
0.047 45 3.100ppm Mean: 0.6534 ppm.
Semmens :
0) Setar oF ocenabotiol one ao feller:
"escoccumin
Cle
SCiota.) TEE
* FEP Service Operators
- Poly FEP Operators
Fe sugnision
-- O.Bopem..per. yeasiofFEPwork
= 0.35ppm peryearof FEP work
-- 0.07pom peryear: of FEP worl
0-8 Tn Blood Levets Gre Beginning To Trend Dowmursac
(See Attached)
3
000174
EID080689
C8 Tn Blood (ppm) Dake oF Sample. C8To Blood (ppm)DsteOFSomple 7% C-8 Chang
4.900
1.200 /. 700
4.600
1.500 &. 500
3.700
8l20l80
shslso EIA]
S l2tlso
82a ls 826 80
9218
5.800
1.300 boo
5.300
I.&00 4.800
2.100
8lar)ss
Cinta gliefs
gsr
83s) 8|slel
s)ia)sr
+18
+% -0*
-20
-20
a4
-43
# Mus do the 10% error i Te CFanelyeie
Fase Lio chargee Should Qo Aaoh ute ann ce LES wncertani if The change adatty Qeamed or
orcle Ho analpraiproond. Thetefore, 7 aut of
5 op The 198) necamples show a olawnwand_
Mund ne FEP worhera.
Querage Ocnone in. C-8 Blood Lirets io 3% ren Ge Gunage Gard of Qlmost [0 mothe
, 000175
5
gg
EID0S0690
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10/29/81
Erplegee to. See Age Gah Gril fal Sn
2:
Fxg
0.06/
0.053
x
Fo a7 osm
6.390
a
!
Far o.190
0.170
a:
NY
0.065
2:
iF 37 ado
2.000
ai
F 32%
0.450
0.410
a:
v Fo 27
6.270
0.240
Rs:
7 [A
b.140
0.056
EY
Fo af
6.110
0.086
a
Fo 27 160
4.400
Ba
F a7" b.110
0.09
2
4
F 33
0.0/9
0.019
x
F353
1.300
0.980
3
/ F 27
0.192
0.720
2
d F *7
0.230
6.2/0
8
3 LE
&.500
K.bo0
7
3 Foo as
6.093
0.073
s
0 oF 2 0. 045
0.0t
Sean OM @
(Joi decreass 1.01% 9.9%
0.450 0.230
0.045
0.920
6.440
Bamate oleate enty) decneasco 10.04 19.9%
0.061 0.190
0.078
a.4o00
2% 6.270
000176
128 =13.1
140 =e
R27 "les
He =/e7
125 6.7
7 --8.9
30 lll 193 ~38.
128-8
126 - 13.7
33 11.3
123 co.
i126 --24.6
/27 --37.5
27
8&7
26 + 4.0
12
0.0
5 ~89
i -30.4
Rais datadosotezt
0.110 I. 300
g
EID080691
decreases S00 8 39.9%
O. 140
o. 192
o-Ge--
no nek movement
e.c19
0.092
amowiacs
2.500
(3) dicriesrs Rom
(3) Chowasss from
ot 10%
Bob Ho%h
(ous tise) -- Leneto atl Belo 0.5apm
172
-- Lo(io.s1Ho a=toh57C5t)ew 4.idpom
Chagfhast decreases)
(1) diovan Frame lo 52% - o.otl --5,100
(=)
"
" 20 & 30% -- 0.11 = |.300
decwaass 1.0 % 10%
" lo te 20% "20 te 30%
a0 te H0%
AF
32,27, 26
a3, 3,27 .37,29,22,27 21,33,
27,33 97, a
"a:
28.3
2.7 22
Eola
no decsaac
33,25,25
28.17
noag
-
000177
Z 2
8
EID080692
