Document 5LRG4g9d62EDqpxgmMJBpVwZV

1 .impurities is tremolite which is a thin, straight Page 450 2 fiber. 3 Q Now, Dr. Gabrielson, do you have an opinion, 4 again, with reasonable medical certainty, as to how 5 asbestos causes mesothelioma to develop? 6 A Yes, sir. I think, although we don't know 7 every single detail of how asbestos causes cancer, I 8 think that to a reasonable degree of certainty, we 9 have a very good understanding of some of the 10 essential processes that occur. 11 Q And have you brought along -- how, in your 12 opinion, does that occur? 13 A It occurs as a result of the asbestos fibers 14 being inhaled and then transported to the appropriate 15 site in the body, either the pleural mesothelium or 16 the peritoneal mesothelium or even the pericardium 17 mesothelium. 18 And then it involves those fibers having 19 effects on the mesothelial cells themselves, causing 20 chromosomal damage and causing cell injury. 21 Q Now, Doctor, in your opinion, can chrysotile