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496 MINNESOTA MEDICINE tered regions of thickening in the capsule. The cut hypertrophy and finally to dilatation of the right side surface was mottled yellow and red, and there w as of the heart. The systolic pressure of the blood was definite fatty change in the hepatic parenchyma, - not greatly elevated when It was recorded, but &
The anatomic diagnosis th at was gfcei took account diastolic pressure was relatively too high- The heart of the features pm mentioned ta d included * notation Weghed as much u any hearts In cases ia which of shicoris of ti>e tongs. MietOseOpk eSuunfaation o f hypertension was the uaderfying lefhal factor.' The
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.^otssftsSSv
$hlerf8lB--d6KBS,6 B' emqfteto heart Mode was fear#? to he explained <m
cells that contain] quantities o f Mood i% Reat were the ta la of partial obstruction. There teemed to to
noted the alveok of the tongs. Special stswn fo r no final answer to several question connected with tto
iron demonstrated iu presene i t e f e Md Mm ewe.
to the wall* oif hWtoood v?es*s!e&ls ta d ,
" 'qn-
I 0 he aMtotonwe toertowae tfe ti* i
r t fc tissue to tfice tong, Jftjp p it was very
& *% after the death o f tin* patient, J c & ode of ^ hmtoess parine, and m
~ * ` *efcg*. I also wrote tl She Mt. o
thtok of. and k e d f,
During the fimti sum * o f the recti to tide woe there were observed certain pecafiar, hrewnUh, fibrosa structures, mmrent^ foreign toxfics, to toe tissue front
the hmg, usually embedded to ctaaqctive tissue, and
his dcafh, t o paticnt o d h
onsidcfaWc time to febalstion of asbestos, o r any material 1 angular partide u we a I
often engulfed W tug giant ccBa. -ghgp m m to t M orcth an rig h t m onda ffer tito le tte r..................
Out ordinary rtatac, and some of them were town to * bariiWM Heriste eaHed oh me, and stated thai be
eomafe iron fcy the Prussia Mao xeartton. Ttone w much discussion as toihetM tonrof these bodies, with-
fbat t o dcccucd had, as a youug man. torta* mine m Souto Amerito. Lab*
oat any eonefeitoa wwfdered that itoar
m
toes M eto re to at wbito toe to d toa J Sonto America fie fiad rilfe
that to re
mm&m -
T*erew i *n krst<*ry0f n tlito:;to ;to iiiio t M jattA
to totof. tote The shoi M es wcre eleamd PmamaMy tito w w prior to Bfi, wto he
certain w ares,t differences were observed between the rraclluns of these fibers and those shown by
to te * r toast torfy-tw e y u n befar his
merdaOy prepared WbMOh strengthened rather then wcahear the bodies wtr
of the Inga was to snow amp ujmdcd
htoff and heart m t tildi. I t o m t o A la r tonti niece* nf mrtihinni.
presence of these iaretgn btofiw. th e Mw we ferther :UM !Swh muta, A ' ooemuote i tta a-
enicrtatoed that the fibredi of 4 loqp w km * .
t r tam wiik ten oc o tta, t u * ) * (ta t to
tibia for pngreMve mcreare to toltaeaec to the dr*
: ticen entaddctf lo (ho aotalknc o( ita fato. I ta
cHtauoa through the organa end may have ted to
coMohe m niiM u) h t(c aotooot
o f fef.whMii cpflrefcd iptty add on tlie surface of be Sq$M> T bit * not 'd ear yellow, and a smear of ft w n made, with the idea A at some o f the fibers might havetocseaaghf hi this m aterial a s# thus pro-
vented fmn scflSflf to ft bottom of the heavy Add. The sediment collected from the bottom, after washing.
These asbestos fil*ert Ad sot show more plainly by
polarized light The golden-brown olor o f the fibers '
was a distinguishing feature under the ancroseopfc
Smaller fibers of asbestos, when
epata,
seemed to have undergone change* not bsrved a .
larger fragments. The butt end o f one o f fliese fra ^
was found fo cantata a few fibers, together with some mem* is shown in Figure 1 It had tocan re&tged
smaX particle* Of siika. Such drastic treatment as and knobbed. and had a distinctly brownish dar. There
boiiing & ftamng Uri acid would destroy most n o - seemed fo he an envelope of a lighter M d t dor
tcriste even the finest A tm of asbestos, but would about a darker center; the latter was continuaos with
probably not affect agpiectabty the larger ones.
the fiber Aside the giant tell. The frayed end* of Am
h i the scam fla t t*Qctcd on the surface of the Anar gave pUee to the goWen-brow val todies, where*
solulion Of nitne meid were found several fragment ms that portion whhin the giant fl was the' lernst
that were m tety asfalto*. The largest was mere changed- The majority of asbesto* fiber* of stud! Atm than 1 mm. in length fffg. 1). This had the definite lay in a confused mass of giant cdls, which seemed
cross striations that are cmreeferi of altered tab - to represent a foreign-body reaction. In Figure 4 hr
tos fiber*, as dereritetf tty various observers.* When shown s scattered group of Store, among whidt o
viewed under jwlarised tight'* portion of the mass to seen giant cell*; the adjacent tissue o f the lung ha*
was dark and there Were brilliant strode* through it, toen undergoing w tcrsttai fibrosa, The Mtosto*
thus dupBcating the appewuaee given tty a known fibers were readily distinguished from tattle tissue
ample o f Aretes from commercial source*. A per- fiber* by tbeif gtdden-brown color; the fibers of ru stic -
tion o f the mass o f asbestos had a yclkm-frit-brown tissue took a titaerirmwn stain with tomatruyfia. The
color of Cjcaetiy the nature and shade prerouted Ity the former were unchanged by ordinary antime dyes,
control sample, The physnat configuration also agreed whereas the latter were readily tinted by various . -
vritfc what m e woubt emmet o brete*.
methods usually applied to weh tissue.
la >o* 2 are-rite. ihp testos fitore m a smear I relate areas the prove warn relti mure advanced
where tjtey appareaifljr had beret spread through the and connective tissue of mmore mantra type tnte teen*
tissues the microtome lutife. The section te whkfc sometime in snore or )eu efreunweritod areas. Stttfe
ttoty were found had am toco ttahred. A few golden- * nodule of scar iwwic i* shown la Figute S, hut Ate
to*? fw f todte w e> *t srilh tito fibres, sug is sot entirely enajpwafete to the w*cal)c& siftcotfe
gretwg m t
in titeir structure had tafeen oAries found fa cues of *Ukb m which tutowattoris
jtaWktefti* tNMgtiteiof tim mate m an indicated that jday* mpart.
.
ti m re had hecs. protected from this change in fhe There sccmed fittfe doubt that many of the asbesto*
.ppefc
affected ntettte the finer fibers la d here most compltete removed freu* *
- fibers,
rdmlvety unchanged tissues. The frequent assodttkm of pretty A rM ' '
foe tid* teoq preiod of time. S earch made far ti Awn and the goldco-browa evai toxfiea fltowttb .W
dttitte tis: Aires toot (he Mood resete stet te A e fitem tittle doubt tfcct A e tetter were derived m m .-
ftiwm & w alte hut they unid hufte he Atttagwsfaed. ti lorn. They wore often te ti same teste: etiL
9M s*$w
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