Document 4vL5yawn62QGxQK0j7mo4mQZj

FILE NAME State of the Art Literature SAL DATE 1924 July DOC SALO04 DOCUMENT DESCRIPTION Journal Article - Fibrosis of the Lungs Due to the Inhalation of Asbestos Dust fone JULY 26 1924 MEMORANDA = MEDICAL MEDICAL JOLABAS 147 teal The blood urea was 46 mg per 100 c.cm. There -, no clinical were symptoms of renal inadequacy no thirst or bead- silicates and 40 per cent of SiO silica The mineral fibro achie and the tongue was fairly clean The patient though is quita trauslucent except at the fractured ends where thin was in fair condition condition and had been at work till shortly before admission some change takes place the fibre becoming blackened and fragmented Asbestos dust no matter from what theOn November 8th the left kidney being judged the better of the process it is collected contains these blackened part of particles two nephrolithotomy was done on that side through an i^,,large amounts see oblique micrograph calculi lumbar incision and masses of branched phosphatic A throughwere removed through a cortical incision in the kidney since wtoheman aogfed 33 years had worked in asbestos factories pouched and thinned calculi calyces which contained the tissue opening into the ; drachms were thas ceasing woargke in J1u3ly bu1t922forhefrivae ttyeeanrdsancpersevaitousthetofahcetrorfyinhalaldy been intermittent The removed and renal area drained The The upper third of the She died on March 15th 1924. Mr. N. kidney was that chiefly involved and the remainder showed Molesworth coroner for Rochdale at the suggestion of Dr. sound secreting tissne The patient made an uneventful Mackichan who performed the necropsy sent the lungs for and recovery from this operation and December left hospital feeling well on further examination 11th He An ray plate showed extensive fibrosis more marked in the returned to his home in Bloemfontein and was right lung two calcareous glands at the root of the left lung admitted to hospital on January 11th 1924 for operation re- two small calcareous particles in the base of the left lower and the right side The left lumbar wound had healed well on On this occasion the urine from the bladder showed 1.2 lobe Macroscopical Appearances area marked improvement the per cent left kidney urea was 1.1 1.1 upon previous occasion the cent the blood Right Lung pleura is thickened over the entire surface of the lung and shows the remains of dense before 46 mg per 100 c.cm. urea was as Cultivations from the left chest wall and pericardium adhesions to the The lung is firm and kidney showed no organisms there was a scanty growth of a coccus from the bladder urine carmine strepto- glands at the root of the lung are larger than small The section are black show a thickened normal and oo capsule and the left in thirty minutes with a free urinary secarpepteiaorned Ffrroomm particles On section the lung is seen to be fibsroomse ed caalncdareous the right side there was a rapid arrhythmic secretion of a large extent airless the lung tissue being replaced by to a fibrous purulent On urine indigo carmine appearing in fifty minutes tissue In the apex there is a large cavity the size of a January 28th a right lumbar oblique incision was peeled Tangerine orange The middle and lower lobes show made and a much sacculated kidney was exposed the being mainly in the upper pole Masses of sacculation phosphatic calculi numerous small varying in size from a hazel to pin's head caseation some of which have a cavitation The proceeded to weighing 11 drachms 50 grains were removed through a cortical bronchi are dilated incision in the thinned upper pole pouch This left Left Lung pleura is thickened and shows the fabby upper sac leading to the calyces which had contaainbeidg of adhesions to the chest wall remains The thickening and adhesions the calculi As the walls of this sac showed no evidence of are not so marked as in the right lang The lung is firmer secreting of the tissue and as it seemed only too probable this portion kidney would never heal and only leave a persistent than normal At the root of the lung are two large calcareous masses one the size of a large hazel the other about half fistula the sac was completely resected that calcified tuberculous glands The other longitudinally deep mattress sutures of catgut being used for haemlongoitudinalsy tsao sm ise black and show a thickened capsule glands are On section the lung tissua and the edges then approximated as but room for accurately as possible cuts with there is greater resistance than normal In the left apex drainage being allowed for The kidney kidney area ras drained the tube passing down to but not into the renal an area of old scar tissue about the size of piece and a cavity the size of a walnut a sixpenny Scattered are small throughout long substance The tube was removed in eight hours and replaced by a small gauze drain Hardly any leakage occurred tha lang some areas of denser consistence than the rest of of which show definite calcareous others si^-allareas of particles the Epxacteipetntfohradan attack of malaria and dysentery from which caseation in the fibrous tissue There is a considerable increase previously suffered in East Africa no untoward . event marred his recovery On March 1st the patient walked then a distance of a mile to report himself he had then no urinary Microscopical Appearances symptoms and the urine contained contained only a very small amount of The right lung shows extensive fibrosis pus and under hexamiue and acid sodium phosphate was acid cavities with thick fibrous walls caseous foci and Giant cells in reaction : around the caseous areas and tubercle bacilli are numerous The case can be taken to be definitely an The left lung shows the same are present not so extensive condition but the fibrosis is ascending urinary infection from the original cervical injury with In sections of both lungs in the resultant formation of calculi on both sides There is positive evidence to show exactly when calculi were firnsot fibrotic parts are seen particles of of various shapes but the large caseous areas mineral matter and in These the are area formed but as a medical board board held in 1917 in The size varies from 393.6 to 3 majority have sharp angles England The stated that the patient had bilharzia one can microns in length micrograph illustrates the sizes and shapes The photo- ry haematuria Par he then had though there was assume glands show periadenitis and lymphatio fibrosis adduced to prove that he had bilharziathat inso theevriedence The bronchi are dilated the lining epithelium has dis- "Te no statement that ora had been found havo been assumed becausebecause the was It seems rather to appeared and there is extensive peribronchial fibrosis Africa patient came from South 3 The resection of the upper pole of the Memoranda proved quite successful and is well right kidney cases of similar type worthy of adoption in The chances of MEDICAL SURGICAL OBSTETRICAL calculi are considerable but there is recurrence of this may be prevented by keeping the reason urine to hope acid that of drugs and diet acid by means ENUCLEATION TIBROSIS OF THE LUNGS DUE TO THE INHALA- TION OF ASBESTOS DUST BY BY disaster W. E. COOKE M.D. F.R.C.P.ED. D.P.H. sO, PATHOLOGIST WIGAN ENFIRMARY ENFIRMARY With Special Plate - present sleep THE in following case is of importance importance because it is the English medical literature to be first Medical men in definitely proved lave lung areas where where asbestos is manufactured suspected the dust to be the cause of chronic and buchitis shown that fibrosis and Professor J. M. Beattie bas guinea Contains shown Contains the dust causes causes fibrosis in Contains Shollest ath Asbestos | | LYMPHOSARCOMA OF THE TONSIL REMOVED BY bluder's GUILLOTINE LYMPHOSARCOMA of the tousil grows so rapidly and when removed so commonly returns or gives rise to leukaemic tumours that I wish to multiplo report one case where removal kas so far been followed neither by local rence or by remoter metastatic recur- months have passed since the operation though twenty In October 1322 I was asked to see a lade aged 52 able to swallow Huids unir and complained of who was shooting to the left ear severe enough to pain in the throat Tonsil was enlarged rud almost touched the sleep The late faces It was very hard and opposite opposite side of the Met of torizout veins which cosntmroaostthed avnidvidw ia r s covered with a, inter pallor of the with the MANOSE tumour there was underlying a ranged growth At the upper pole craterishaped Liquisfelt of te /ensati ulter the size of a threepenny piece The tumour was movable be no placis could felt very moe told me that in 1377 1377 when mans of metion bone became became fied <we:.--7 a 27 years of age 1 her left tonsii a sharp causing frogs much much