Document 4apO9dN4RwYGyV9xLbNpNn6aa

O 3 4 o! Q Ji Dr*. 3amuo 1 RubIn 33J ?atap3co Avenue Baltimore, Maryland Dear Doctor Rubin: At the request of my associate Dr. L. J. Schradin, I am sending you harawith the results of our analyses on samples of urine and blood obtained from the group of men involved in the cloanlng of a gasoline storage tank at the Curtis Bay Terminal of the Tidewater Associated oil w oiT.p any A few ccmtnonta are justi fied In connection with these data. First, the blood findings on the group of five man who v;ere most seriously exposed are uniformly low as compared to the result a obtained in cases of inorganic lead poisoning of corresponding severity. The results are in good agreement for the two methods of analysis, although In the one instance of W. T. Witter, we are dealing with a somewhat larger analytical variation than is ordinarily seen. The average of those two results in each instance can he accepted as somewhat mere accurate than either single result alone. In any case the blood values are low as compared to the urinaryvalues, except In the case of.Rogalskl who, presumably, had very little actual exposure. This discrepancy between the blood and the urinary results is characteristic of tetraethyl load poisoning. In which-case the lead com pound tonds to be distributed more widely, and especially in the fatty tissues of the body, rather than to collsct In high concentration in the blood. Perhaps ou this account, but possibly because of the differences In the distribution of lead in the body In the case of thi3 compound, the urinary lead excretion tends to be con siderably more rapid than in the case of Inorganic lead poisoning. For this reason the urinary' concen trations in severe cases are likely to be very much higher than any value In inorganic lead poisoning. From our experience it can be accepted that urinary values give the best clue to the relative magnitude of the lead exposure, and In the case of this group of men, this would seem to be borne out by the occupational histories of tho men and by their clinical course. 2 These analytical data are obviously of scientific and academic Interest only in connection with these cases, hut I felt you would probably be Interested in our interpretation of these results on the basis of our previous ex perience. If there Is anything which I can do for the benefit of these men, I would be glad if you would call upon me. Very truly yours. hoberfc A. Eehoe, M.D. 0021141