Document 4aJD79Q1EbB3qGyryKvLGy3o1
Monsanto
mo ,h,m. Lo^oN, Wllllam H. Hunt - Medical
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April 29, 1970
Aroclors - 3 Generation Rat Reproduction and Pish Toxicity
"ro : R.E. Kelly, M.D./E.P* Wheeler
A visit to Industrial Bio-Test laboratories, Inc., April 28, 1970 revealed the following progress to date of this study:
The first litters of F*>were OK for 1242. However, the females .
_ for PgB (second time around) failed to become pregnant at the ('*-e'"rr
ft/tka** ]_00 ppm level. The other two levelB were OK. Only 1 female
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had pups which are now 12 days old. As a matter of fact only
.
I 2 or 3 of the 16 females are pregnant and they haventt delivered as yet. It is planned to remate these femaleB for 1 week to see
what will develop.
Regarding the fish toxicity Btudles (catfish and bluegills) the
time scheduled will be 2 to 3 `weeks behind because doses which
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were believed to be OK produced 100^ kill.
__
At levels of 1 to 10 ppm for both 1242 and 1254, for 50 fish per level, all died.
For 1260 at levels of 10 and 100 ppm there were a few survivors
' at 10 but all were dead at 100 ppm.
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TOWOLDMON0046104 WATER PCB-00037081