Document 4LX6xMB6qMrDmJZOeJdj81Dp

V Biochemical Research Labcrat: OFFICE COPY The Dew Chemical Company /,, * * - > "O / Noted E.E.D. FEB Q? 1S53 EVALUATION 0? CHEMICAL EXPOSURES RECEIVED 5Y R. R. SPENCER C? COATINGS TECHNICAL SERVICE, 433 BUILDING P1.2.0 12.1-1--* Chg. 1219 Date 1-22-55 my: u. E. Petersen Signed liLNTy /yvtdur^ Date 1 / / -2a /^? Check ^at e d -* g - -i T PROBLEM THIS F=C?>T IS T:0' PPOPEPTY CF Recent1 y, R. R. Spencer has become : c Labcrat cry was requested to deterni: c c by him, and to assess these data. _ I' DOIV CONFIDENTIALc CCNCLUSIO Dxrcsures to air come materials during the f: mining, anc calendering c. vinyl assesses oi_e in vers evaluated on 12-23-54 and cn 1-15-55. Results c; '4caco Scenter during hi3 work with this material, <3 r> o--r.` cer -.3 zest cs :: tr.at vcr>: was occasionally exocsec r; -a*--"--r -- J 3 zest cc * -0wuat excessive DAK OJ. 115 Biochemical H.esesrch T2.1-1-55 Paze 2 . ccratcry During this period of tire exposure to lead occurred, cue his bleed lead level on 5-7-55 was only 0.024 mg./ICO cc. bleed, a normal figure. Exposures to cadmium du'"rir'ng this period vers . to airbcrr.e concentrations cf "4 0.7 mg./m'1 ' -t intermittent periods. No effect is expected as a result w -- hese exposures From the first part cf 1555 to late' 195c Mr. Spencer worked mostly with latex in concrete, and exposures to vinyl-asbestos tile ingredients were reduced accordingly. 4. ?rcm the last part cf 1955 until the present he has been r- working with vinyl-asbestos tile formulations in a supervisory v_ capacity. During this work he was probably exccsed a maximum cf 1-2 cays per week to airborne dust concentrations of less than 5 mppcf cf a material analysing 20-30% asbestos, less than SLC,,, and about 0.02% cadmium. No effect oar. be extected from such exposure. If !tr. Scencer1 s difficulty i3 the result w. ______________ ^ - exposure, the c'usitlve azer.t ts urxrcwn at sreser.t 2--2 " ' 2 o <2 . j. . _-.e vr.er. - J -2 - / r.e r - V- Q vn dak 01116 * nr 3ioch.2rr.ical F.es ea-- - T2.1-1-65 Page 3 PRESENT.;? ICN CF . Scencsr has been ill with a l1u"nngc- dr 4 * * ' r a no. cverexccsure to chemicals encountered during the fcrnuistion, nixing, and calendering cf vinyl-asbestos tile formulations was suspected ~ u ^ C3LZ.2S cf his ^ 2!Lr'<:j2s "^'^0 ^*"ivP*2S^**c^ *p^ was ''^''usstsd tc d.SwSr*mJs 2r*ci 0 v 2 i li 2 ~ 0 0x202utss On 12-23-5^ an environmental survey cf the vinyl-asbestos tile formulating operation wa3 made by S. E. Johann; the results c this wcric were reported cn 5-5-55 (File Number, T2.1-1-52). unis survey found that air concentrations cf ' inerts(asbestcs plus ;u;c u urn carbonate), barium, and lean were toe nlgn ter repeateo c-hcur exposures , and even though expcs'ures were not that pro!cage -- o/->/- ---- aa21^.9 Ins^22.1.2rlcn. c*-1 lcc2i sxr'SUST C2c.tj'" was determined in the air samples, cut tresent was below -U- - ' -< cases the amount the analytical - a <o o--cloyed, "^ad"1 -- -- tc .or. 1 inures cf .-r1 - cto mg./or and ' less than J - -r- DAK 01117 -O - - ~ ~------------ - J c? ^ r--.v' aeesrJ;a:icr. S9vsr'2.. cr.2r^zas v/0 ---- o mo r* 0.2'- r.i , ccera - icr.2- Zzcr.r.Lzues vrers -a? n a <- Biochemical T2.1-1-5 5 ' ' Page d lacc'^"a ~ :ar.cpy heads -were installed ever the large 2-re 11 -ill arc ever the calender, cut net ever the small 2-rcll -ill usually used ier trelir.ir.ary cer.rcur.dihg ci these fcrr.ulaticr.s. ** 3 i i *r - ------- J t a -`* Building Preducts group recently r.oved into new quarters wher a tench-tyre heed is always available to central dust from dry U1 ir. eenr.eetien wJ___ -hs smvizrcraT.sr.ca 1 s'acvsy c*"* 1^ satirles were taken b iced--^ sah cisbszrm^ mac icFs -an involved cn this project. R. R. Scer.cer's diced lead cer.csntratier. was found to de 0.02^ rtg./lCO ce. of diced, a normal figure, indicating insignificant exposure to lead. The ether two r.er J~vclved also had normal diced lead values. G. second er.vircnr.sr.rai survey cf the vir.yi-as testes ,3 *-- 3<3 ***3 -- 4 ns was na ~ ~ > r -- - - -- J Lc S 6 2 S CC.a8 3 i m* * O r* r* Ck V'"* - <3 * Q. <? r- * "Otm; r*i"o --3 Uq ~ 3 *" " 1 ioya ^ ygn y,a^or" a <- J 3 O J 3C9SCCS 3 C 3 "'(3 ~ 3 C a r* 4 -- a i3 o dak Oil!8 * T2.1-1-55 ?3gS ~ The recipe is as follows Ma *" * n 1 Weizhc Rati Res in May te chlorinated polyethylene or resin 2716, the copolymer of 15^ vinylider.e chloride, 5^ vinyl chloride. :tyl phthalata or triorssyl phosphate 17, Mcncplex S-38 An epcxidized oil purchased from Rohm and Haas. Metasap 624 Contains cadmium laurate .on stearate ~a r wax les ir.it - Calcium carsenate No. 13 n * **1 * ^ Sarv* _ A very fine sand Titar.cx FA50- 'Titanium cicxide Astestcs shorts, type 7M 2.2: 1.5 0.1 0^ -^ c ---- > 3.0 19. C DAK 01119 & OY~<=' 1 * ,4a* :icctyl phthalate and mcncplex S-3c, c: Sr's v/slrri~.sc inrc 2 333.1.n2.sss srssl. r--'lrcl.~ 'revI ir on ~ -- ' a (3/-< 77 -- n- m ~ -1 TMo" 7/* *3u u ti ccc. "tl_x0ci **'3r* 2 1 2w t a "'<=> s> m /- *- ^ *"*. * - - a --* 4 v 4 y powder; O- . j ,, w ~; T2.1-1-65 igr " .ccratcry sr.er. it is none, weighing and blending cf the ingredients takes place at a maximum frequency cf about 3-half-days per week; an average frequency is difficult to establish because two cr three weeks hay pass with no activity in this area at all. >tr. 5cer.ee: normally would be involved in about ^ cf this work wnich is usually done by a lab technician. Dry powder fror. the paper bag is poured directly into the BakerPerkir.s cr Banbury mixer - usually the Banbury. Here the material is forced into a heated mixing chamber with an air-pewered ram and i3 mixed fer about two minutes. The resulting mass is semioiastit, and is removed (sometimes w'tb di''"',', cultv) from tr --ix=*' and carried to tue dif^ere^tial steed hat"d (500 --"C0". ^ c.r1--* ~ -- o ^ as Suer, bler.dirx mav take from 2 cr a half-hour detending utcr. the difficult! DAK 01120 ,^:ter teing th. ~J****** 1** **>***&** r-------J -------------------- ~ --o . -s. i -____; ` m 4 art he calender (basically a coder 03 -- O r a :ew :ee~ awa' ITo e ~ a -- n ~ 0 -t* * ^ 3 3 SCl<:s<=i'*~r 3 -> a o - 3 - <3 ^ 3 C ' ' -- J --* -- o ,, -_ 3 --3 - 3 ' r ''* * * *-> 4 0 <0 -- ** -- -- o 3icchemical Researcm laboratory T2.1-1-55 Page 7 The maximum frequency of this Job i3 about the same as for weighing ar.d blending, 3 half-days per week, and again, an average frequency is almost impossible to establish. For reasons cf safety, two men always work together in these operations; Mr. Spencer has been associated with about :C^3 of thi3 wcr: 3ir.ce the latter part of 195 Cn 1-15-53 several air analyses were made during tile manufacture. Air sampling equipment used was he .caused and Tomb dust counting nicrcsccce and the electrostatic orecicitaccr. Results cf these air analyses are presented in Table I. Samples 1-11 were taken with the 3 and L dust counting microscope and the ccrcer.trations are expressed in terms cf millions cf particles ter cubic foot cf air. (r.ppcf). Samples 12-Id were taken with ripitaccr, and normally concentrations would be extrassed as a.C a ^ __ i^ of air (mg./or*), but the samples were unfortunately cf obtain weigmatle , - ^ - w - J - , DAK 01121 cc grp 3 ^3 T2.1 i-55 raze aS6-',,'u oratory Tat:ls I Description Dust Ccr.cs none: a ion t An air sample taken directly ever a pater bag cf dry materials shaken to produce dust. This sample was mainly tc establish the size range c^ *zwS al_ircc^rr*0 r'ar*^Jc'lo3 Breathing zone sample as a paper tag cf formulation was dumped into the Banbury mixer. Sample cf fume from the hot semi plastic mass as it was withdrawn from the mixer, net a breathing zone sample. Breathing zone cf a man removing the semi-plastic mass from the Banbury mixer with steel picks. -reathkno zone while working the * ta p g y "1 g "iti C* _ y y 1 "O' Breathing zone while working the "3 t 1 p *-* 0 "1 Breathing zone cf man as he tut the material through the calender. -^03^*^""3t*s c 'Z z z "Lt** z cl.2s wC cr* zrs sr*s3.r, D r* r- g 4 -* J ^ "'--0 g ' *"* * ^ o p 0 h" ** 1 3 'pj mQ -- < 'C'-' s re added try as testes fiber ;; --q -- + *r 4 ~ ~ r ~ *2 4 ~ a s- t |u o Most particles - zx in diameter average about 2 -3 X 3.2 C. 7 Ck / C .2 y-- 1. (() dAK 01122 * Biochemical ?.ssearch labcra-crv T2.I-I-65 J Faze 9 Sample No. Description Dust Concentration, MPFCF Lmmediately outside of the bench heed where the dry batch of material was being mixed. 0.5 length c Time of Samole Dust Cpr.c 0 12 Electrostatic precipitator 2 min. Too little to v/s sample in the breathing zone while formulation being mixed in the Banbury. 4> 0) 13 Breathing zone while working the formulation on the 2-roll mill. Too li measur Sample taken in bench hoed ever the container where the dry mixture was being stirred. This sample was taken only to determine the relative crcocrtiens of the dust constituents in air CaCC- - Main Constituent Asbestos - 2C-3Cm SiC, <3r* used for the tile formulation involved i r. the work described in Table I was resin 2716, consisting cf -- 0 r> CT C7Z -5$ vinyl jjapo viry1 ^^^ ide. Analysis cf Sample 11 was by x-ray diffrac^icn and eniasicr. c 0 / -- ^ -Uo <----5- ' - "-'J --a -- 1---- : (Z CO cr DAK 01123 * Biochemical Research laboratory T2.i-i-65 Page 10 The dust concentrations shown in Table I ray be centered with th appropriate Industrial Hygiene Standards, listed in Table II. Industrial Hygiene Standards are concentrations which ray be inhaled as much as 8 hours per day, 5 days per week indefinitely without ill effect. Table II Industrial Hygiene Standards Material Standard Asbestos Silica (quartz) Cadmium Calcium Carbonate 5.0 mppcf 5.0 mppcf 0.10 mg./r3 15.0 mg./m3 Hesin 271o r* 0-2-- j -- p 0 eg. /r c c r- C c An examination of Tables I and II readily shews that at no tins were the standards for asbestos or silica exceeded. Sine: the dust counting nicrcsccce determines the number, not the we: c^^wlclss b.'L'T serrs 2.3surr.c"icr.2 rr.us3 33 rr.2.i9 cadmium exposure can be evaluated: (1) assume that the dust p*-*,-*'"'^** -- g *-* o ^ yoa*-* w g Tl C Li *"* Jy 2 -- r* C 2,1. ~ v- -a H - a o *** 4 ^ ^ o -.3 4 ^ 4 3 tri -- ti ^ i. Cr* 23 ** u o ^*3"' ^ u CTV , 2 ^ n 3 S Urr.6 3^3 ^ 'S>3 ~Z 23r'2l.C2.33 '>"0ir0 '/,*J**U ^ 3. V 0 3 2 3! 'j---Q-a-- ^ ' 2 * * c r 4 S3 j ~) 2 3 s 2r.e tr. 0 cer.2 Itv ~ * - & ^ 2, r* 21.2 10s DAK 01124 Biochemical Researci T2.I-I-65 raze 11 ccratcry Using these assumptions, the weight concentration cf cast ccrresccr.d to the highest observed particle concentration (3.2 mppcf) would be :3 1.S5 mg./m. . Then, assuming that the particles were 0.C23 cadmium, the air ccncentraticn cf cadmium was about 0.CCC4 mg./m.-5, well below the 0.10 mg./m^ Standard, especially considering that all cf the assumptions made were conservative. Thermal decomposition products cf the resin and plasticisers used could conceivably be the cause cf trouble except that a great amount of experience at Dew and at other companies with these materials has shewn that no adverse effects are to be exoected even under much worse conditions than have beer, orsvalsnt in (. c DAK 01125 Remaining as a possibility is the dust ar.d/cr thermal deccmpcsititr. orcducts from chlorinated polyethylene, a r.ew material. A survey will be made when this material is again used in vinyl-asbestos tile formulations in erder to determine what materials are Inhaled, and in what concentrations. Also, this dust, along with the dust c: ** U a " csrlais, 13 seen eo ee investigate:: en q a -- -- o <- e~tl1c-r. caused 'ey sue- 1 r> - -- 3 *-O-- -o* *** O " a y* I JJ -U ' Q ~ q & ** ~ & r* tv t.ae resins used in vinyl-as test to tile f emulations . Biochemical Research la boraeery T2.1-1-65 Face 12 6 t hoed used in the laboratory for dry nixir.g was evaluated by r.easu: ing air velocities at the face'of the hoc d with an Anemcther Air Mete; . The attached "Hood Survey Data Sheet" is self explanatory.* egardi.-- findings and recommendations. O' JI U U O 13 (J DAK 01126 * HOOD SURVEY DATA m man---------fj i - t-J2~ -M6 isiXTiOm. iiui^rnsr D1 :TPtQ^000 \\jjr\r?\ Saz_ Z#c NT(INM. lQA\PJ]PLQlfttNj e6iTrCRNPAJ^. dAJD>*\U.kt CT_SOlt*MICAALAS^**O,ClO?I* TTM.IIhOOP t-,-, - -- v& 5 _)_ /V a 'JL<87ZS. PVC_ riAs7ICrziAS . ETC ~ax owBiwiirrs n.i cj iww mru O V E V-S" aaararsi anrjauua mansi-ra rwn aaa An? MFevsea tAJLET A no or p UlUUl - ------ - > ' ScLVf.Vr 0 P #CoD RECOMMENDED MA* FACE VELOCTY FOR THIS HCCO_____________ P Q RECOMMENDED EXHAUST RATE FOR THIS HOCC f I TO_______ Z. F. U. F. F. U_. DOOR CPEH . 59K III I ! 1 1 1 | i ! 1 '1 1 1 I ! ! i : 1 i ! ! 1 ; ! 1n I1111ii1!! !! 1!i! !!!11 |; : 1 ! 1! 1 ! 1 tr 1 l2T(y> 1 \yc ' 1 i iW" i 1 ST j|j1|I;|1 | . r ! 1 ;! iii! i | 1 ! iifs-; ! ... j |^ i 'M !i:!i! : 1 : ! II ! ;<r2 ' : 14.7 : f : 'Ati, :i j ! : , ' 1i< "-S' 1 i~ ' '-- : | 1 1 ' ! 1 1 $5- 1. 50 i 1 i , t-rS SO : i . : ;--------- :--:--------------------------- :-- \1< dak 01127 HOOD CONDITIONS DURING THE SURVEY ACTUAL face veldcties -COO face AREA DURING SURVEY exhaust sate dlrifc survey -AI'.UAA* CPFH'HG HE'GHT MAXIMUM <r Pm. jlSL L FT. M1MIMUM t___ ' PM. cf.r. ''"v fA i. x. MAXIMUM I-COC Face AREA uw .F.PM. 1T ->TT| It l. J. A. a - ti HOOD SURVEY DATA nvi wmmii .ua.OMa mjMiit ' , 5^71"" 1 ; MTi3K..&&; IU'a*.-M*ugjGrT_ia_u_-_ 1 yj 2_17//r-/r? B rrltf'o^mooo JA n fy)l L Q/AJC. p?0 OOr 7~S 2 MR. P1~_S U/.11 I (lTIOil. , 3IIWCU MAMUO IK TMI WOO II aTM'jJMramterirfa"n.i ua ibumCT ivc.------------------------- ----- lajeii it zri aurmizaa imui rsTOTgaw <3Zvr. M SECOfc**>CED HEAM face velocty fcr this HOCO . Ul becc*ehoed exhaust bate tor this hoco I I CTD______c. f. u. F. P. M.. OOCR CPEN W I 0 g~ , ^ I I I1 II i ! ' |: i 1 1 t> rj/i i \60 11i 50 I ; 65 i 1! . ' ' , 1- 1 : :1 ' 65! ' ! ! ! 55 V 1. 1 1 ' i ; i : 1 : ! ' 1 : ; ! ' i 1 J ! ! ! 1 ! ! ill! /'-? ------------------------------------------------------------- -------------------- ;-------------------- ----------------------------------------- 1 11 ! 1 1' 11 ; ;r ii ;ii ' ; w/ ' j ; i jl | | | ! | i 1! ! i i 1 ` i : 1 : j-j- ! 1! 1 .TjT i ! 1 i ! DAK 01128 - HOOD CONDITIONS DURING THE SURVEY vc, ^ -<XD FAC aJ3> CCRIHi 3-31Y5T EXHAUST BATE ILSIHC SURVEY CP^HikC; - 'CHT -~y, ~T < --< ',W3 *ci iil ifAkllUNH VE S'4 CA -- V C Aa x t 5 Ay* 5" MAXIMUM v0 E PM. MINIMUM W< ' -> Mf AM r- ' n, C* .? M. 1 J <wr* iM U /^ / N. MAAiUlM HCOO PACT A3PA itllAJ* >M4tl c- - r a 2 " Jw*T0t 1 XT' ^ 1 >---!--------- . - .. i. Ll>* Tin* '1 i I am an author of ana' have read this report comprising_____ ~ 0r pages withfpages of drawings, photographs, graphs, and checked the data herein against the original entries under Biochemical Laboratory File Number T2.l-.i-65___________________ Cel finished typing this report on compri sing. 13 pages and placed therewith .pages ot drawings, photographs, graphs from an original draft given me by. J. E. Peterson on 1-27-53 I have placed in the plant mail. .copies of this report for transmiftcl to --ar'o-r* ^ o 2ist of* tltis re* Signature "7 <ate ij'io o m iis DAK 01129 Biochemical Research Laboratory T2.1-1-65 Page 13 UNIT INDEX Possible chemical exposures received by R. R. Spencer cf Coatings Technical. Service while working with vinyl-ascestcs tile formulations are evaluated as possible causes of his lung injury. No evidence leading to the determination cf a causitive agent was found, but plans were made for another survey to be performed when chlorinated polyethylene is used as the resin in a tile formulation, and dust of' this'material will also be investigated further by the Toxicology Laboratory. DISTP. :cn R. B. Brubel, Coatings Technical Service, 433 Building N. R. Petersen, Coatings Technical Service, 435 Building H. R. C-ay, M.D., Jfedical Department, c07 Building V. 1. Tisdale, Safety Department, 401 Building C-. Z. Bclstead, Compensation Department, 236 Buildinr W. Snodgrass, Maine. Service Admin., 49 Buiidinc (7/9/71) 1: -L y -r p. *1 n 'i n n i si DAK 01130 * => TZHO) L