Document 4JraxXyywwNGj1qgZx7YJ8vyx

M E D IC A L D E P A R T M E N T Oc c u p a t io n a l M e d ic a l S e r v ic e C A M B R ID G E . M A S S A C H U S E T T S 0 2 1 3 9 August 24, 1965 Dr. Robert Kehoe The Kettering Laboratory University of Cincinnati College of Medicine Eden and Bethesda Avenues Cincinnati 19, Ohio Dear Bob: I took your long letter to me of April 13, 1965 with me on my vacation and read it with great interest when I was not being bothered with telephone calls or appointments. * As you suggest, we probably should have a long visit to really discuss and answer the questions raised in your letter, but I want you to know that I did enjoy studying this material and I am sending you one or two comments. I think the difficulty about dismissing the use of the chelating agents in the care of adult workers too quickly is that there may often be no way of stopping the lead exposure for economic reasons. I have seen structural steel workers with evidence from history and objective changes of considerable lead taken in over a period of time who are earning high wages and are simply not going to leave the industry. And on Page 4 in the second paragraph I think my clinical experience in contrast with your vast experience with fundamental research makes me less surprised than you are when, to quote you, "a man who appears to be entirely well today, and then see him some days later when he is acutely ill, and realize that he had as much lead in the same organs and tissues on the two occasions." Clinical experience teaches that there are so many factors in ordinary life with different stresses: Nutrition, infection, worry, are obvious examples. I think many of these apparent puzzles are related to inability to measure in a satisfactory way, the hazards of life. I hope your travels bring you to Boston, and that we can sit down and talk at some length. With best regards, I am Sincerely yours, HLH/jv Harriet L. Hardy, M.D.