Document 4Ja2nnZw5k8qZBEp6emQ2XQ9Q

*O Dr. A. V. Downes Union Carbide plasties Company Room 1103 30 East 42nd Street Dr. V. B. Ackart Dr. H. P. Smyth, Jr. Mr. V. C. Qulnby Mr. 0. T. Soriba May 22, 1959 "Pood Crude" Cast Vinyl Films Dear Dr. Downest Ve are In receipt of the formulations of these films. A copy of your letter Is being sent to Henry Smyth for his comment* also. X think the time has oome when we shall need extrac tion studies done on the majority of suoh films In order to have proper data to present to the Pood and Drug Administration. Ve would comment as follows on these filmst (4) VBAC-9123 Although there Is only 0.2Q of sine stearate in this, the Food and Drug Adminis tration would Insist on extraction studies stowing that less than 50 parts per million of sine is extracted, they have done this In the past. X am not particularly concerned about the other constituents. (*) TBAA-91B4 Same comments as for #1. (3) VBAC-1142 The only questionable product In the mixture Is fareerll CV which Is a butadiene acrylonitrile rubber. The question Is raised because we understand it has an unacceptable ucc 063606 Dr. A. . Downes -2- Kay 22, 1959 antioxidant In It, Z believe Dr. Aokart tracked thla down. In 1943 we did get a letter of accept ance from the Food and Drug Administration for a similar formulation containing Ferbunaa 35HS90 - 38 Instead of the Faraorll CV. (4) VBAA-913 Same remarks would apply as for #3. (5) VBA~3Q2I There would appear to be no objection to this formulation. Very truly yours. Thomas W, Male, N. D. mh MEDICAL DIRECTOR ucc 063607 p*rte. fc Krt ti K.X*rrH2 1./* v Wlojment r !*> *^f* *?* v*r^- - "V>- - 1 A~ ---; v;.*;;V.>.; .a^g^ri ________ _____ ^ u&W fKrabt* out vlapt Ola ft>r*oltiaaa Jfar, i la fr: prosjooii. Thaldaal adfcurtloti 1# Sahara AIM 5ouut ita all /bod prodaala* - Oil* jUf`^Jjwirtiia 4 *4 to w#i, mdaf Jtba oriUrU aodattac forn mmUAtIt*m willy tfcwaull^tIhtaaita"A*" Uri*i.If (f^apoa* d kaowlad^t at ttarwlatkai. W aocajA fMEPoglMll *VUW"fcrf eoafStjrt, *ftf '"""' ' * " -y ,^~.^--,,.Mr famon rHar<anf apart/Satra* caft'* Sjotilrtlal for &**#li&aa* tfea Allowing lift la eSs^.%. Bfta W^r- ^S** .fHala; fcStC***3 &*&#*& * m. *"S*~ JT; **asvr ucc 063608