Document 444NXJZDpjKe96rDjkvyk44pe

pane sultone. A commentary on the decree explains the reasons tor tne prohi bition (in particular, the carcinogenicity of this substance). 1048*41 CIS 76*743 Hazards of chronic exposure to halothane for operat ing theatre personnel (Danger de I'exposition chronique 3 I'halothane pour le personnel dun bloc opdratoire). Desbaumes E,, Ducel G., Imhoff C,, Rouge J.C. Annates de l'anesth4siologie frangaise. Boulogne, France, OcL 1975, Vol.16. No,6. p.437-445. Illus. 20 ref. (In French) Results of an occupational hygiene survey in an operating theatre of a Swiss hospital, prompted by the incidence of malaise and fatigue in personnel ex posed to vapours of halothane (2-bromo-2-chloro-1,1,1-trifluoroethane). Continuous measurement of the halothane concentration in air yielded aver age values of 5-30ppm, with peaks of 50-70ppm. Inhalation of halothane was confirmed by the presence of brominated metabolites in the urine (aver age 14.59mg/I in female anaesthetists). Halothane in the ambient air may thus be responsible for the symptoms. To prevent the risk of poisoning, in the absence of a ventilation system renewing the air more than 20 times/h, a device to exhaust the halothane vapours should be installed, or they should be removed by recycling the polluted air vi^ an active carbon filter. A perma nent monitoring system incorporating an audible and visual alarm is recom mended. 1043011 CIS 76-744 Value of urine tests in determining exposure to poi sons (Vaieur des tests urinaires dans la determination de I'exposition aux toxiques). Lauwerys R. Cahiers de m&decine du travail - Cahiers voor arbeidsgeneeskunde, Gerpinnes, Belgium, Oct. 1975, Vol.12, No.3, p.175-179. (In French) The first part of this study deals with organic substances. Since these are very rapidly metabolised, urine samples should be taken during exposure, or as soon as possible afterwards. Review of metabolites corresponding to: aro matic hydrocarbons (benzene, toluene, xylene, styrene): halogenated organic compounds (trichloroethylene, tetrachloroethylene, trichloroethane, vinyl chlo ride): other organic compounds (dimethylformamide, methanol, ethyleneglyc ol and its monomethyl ether, phenol, nitrobenzene, aniline). The normal val ues of these metabolites and values corresponding to a given level of expo sure are reproduced. The second part is devoted to determination of inorgan ic poisons: arsenic, cadmium, chromium, fluorine, lead, manganese, inorganic mercury. Precautions necessary for certain determinations. Examinations to be performed in the case of certain occupations (garage personnel, furniture manufacturers, etc.). (049071 CIS 76-745 Blast furnace gas (Les gaz de hauts fourneaux). Goullard. Re gional Sickness Insurance Fund for Northern France (Caisse rfigionale d'assurance maladie du Nord de la France). 11 boulevard Vauban. 59024 Lille Cedex, France, May 1975.9p. Gratis. (In French) After describing briefly how blast furnace gas is formed, the author describes the circumstances in which it can leak out (hazard during normal operation and, above all. hazard due to wear). The chief hazard is due to the fact that this gas has a high CO content Description of the poisoning syndrome, which may be progressive or chronic. Lifesaving and first aid methods, safety engineering (at the planning stage, during construction (quality and strength of wedded joints of blast furnace shell, of refractory brick lining, accessibility and manoeuverability of valves) and during production); personal protective equipment (compressed air fed respirators): staff information. (049t D CIS 76-746 Toxicity of hydrazine for animals of various ages (ToksiCnost' gidrazina dlja irvotnyh raznogo vozrasta). Savienkov M.F.. Benemanskij V.V.. Baianov O.V. Gigiena i sanitarija. Moskva. USSR. Mar, 1975, Nol3, p.29-33, Illus. 3 ref. (In Russian) most ettective means or preventing tormanon oi p-napntnyiamine in 2-amino-1-naphthalenesulfonic acid production is to ensure complete sulfonation of the 2-naphthol. The article reviews research and the measures taken in the Soviet dye industry to eliminate the carcinogenic hazard (modification of the filtration unit, centrifugal separators, washing units, etc. to avoid all direct * ,. contact; periodical examinations of exposed workers). / _ . 1043241 5 2,6 /CIS 76-749 Gastric function in chronic vinyl chloride poisoning ' (Funkcional'noe sostojanie ieludka pri hroniteskoj intoksikacii vinilhloridom), Vajsman V.D., Stulova EA, Gorjaieva LA. Zdaneeva G.S. Gigiena truda iprofessional'nye zabolevanija, Moskva, USSR, Mar. 1975, No.3, p.20-23.9 ref. (In Russian) Results of gastric function studies in 69 workers suffering from chronic vinyl chloride poisoning and in 12 workers engaged in production of vinyl chloride. The authors observed changes in secretion of gastric juice, free acid, pepsin and mucoproteins. The degree of these changes corresponded to the severi ty of nerve function disorders in poisoned subjects. The authors suggest that chronic vinyl chloride poisoning could be due to a disorder of the hypothala- mo-pituitaryaxis. (04325) CIS 76-750 Particular clinical features of occupational diseases in workers engaged in triaryl phosphate production (Nekotoryc osobennosti kliniki professional'nyh zabolevanij u rabotih zanjatyh proizvodstvom triarilfosfatov). AjzenStadt V.S. Gigiena truda i professionai'nye zabolevanija, Moskva, USSR, Mar. 1975, No.3, p.23-26.5 ref. (In Russian) Examination of 251 workers employed in production of triaryf phosphates showed chronic poisoning by these compounds to be characterised by neuro logical symptoms accompanied by chronic gastritis with secretory insufficien cy and inhibition of plasma cholinesterase activity. The symptoms of the first stage of poisoning (after 2-3 years' exposure) are a perivascular form of auto nomic polyneuritis and an autonomic neurasthenia syndrome or disturbance of vascular tone. In the second stage there is progression to toxic encepha lopathy with a hypothalamic syndrome and polyneuritis. Recommendations for treatment (04326) CIS 76-751 Clinical picture of chronic poisoning in workers em ployed in nitron production (K klinike hroniteskoj intoksikacii v proizvodstve nitrona). Sustov V.Ja., Mavrina E.A. Gigiena truda i professionai'nye zabolevanija. Moskva, USSR, Mar. 1975, No.3, p.27-29. 7 ref. (In Russian) Examination of 390 workers in the synthetic fibre industry exposed to acrylon itrile. methyl acrylate and sodium thiocyanate brought to light functional disor ders of the central nervous system, gastrointestinal tract, liver, cardiovascular system and haematopoietic function. In some cases these disorders were ac companied by symptoms such as nystagmus, olfactory impairment, etc., and characteristic signs of diencephalic disturbance. Prolonged exposure to acry lates inhibits enzyme activity, with resulting biochemical disturbances. Re commendations for treatment (04927) ^CIS 76-752 Determination of urinary atrolactic acid as a test of amethyIstyrene exposure (Opredelenie atrolaktovoj kisloty v mote kak 6kspozicionnaja proba pri vozdejstvii a-metilstirola). Ajzvert LG. Gigiena truda i professionai'nye zabolevanija, Moskva, USSR, Mar, 1975. No.3. p.38-41. 2 ref. (In Russian) Results of studies in animals and man on the quantitative conversion of a- methylstyrene (intake by inhalation or via the skin) to atrolactic acid. Descrip tion of polarographic determination of the acid in the urine, modified to per mit a reading by spectrophotometry. Determination of atrolactic acid as a test of exposure to a-methytstyrene is recommended. (043301 Results of comparative studies in white rats to determine the toxic effects of hydrazine vapours in relation to age. Young animals were most severely af fected by acute exposure, while long-term exposure caused slightly severer bone marrow changes in the older animals. (04922) CIS 76-747 Experimental studies on the organic effects of ammo nia under varying conditions of exposure (Eksperimental'noe issledovanievfijanija ammiaka na organizm pri razlidnyh rezimah vozdejstvija). Ivanov N.G.. Pliskovskaja G.N.. KljaSkina AM., KorotiE L.P.. Germanova A.L Gigiena i sanitarija. Moskva. USSR, Mar. 1975, No.3, p.38-41.10 ref. (In Russian) The eariiest disturbances observed in animals exposed to ammonia under va rious condition^ involve the respiratory tract. When the concentration is in creased progressively, respiratory effects and those on olfactory function oc cur later and follow a more chronic course than when the concentration is constant Thus progressive increase of the ammonia concentration is more deleterious to health than prolonged exposure to a constant concentration. (043231 CIS 76-753 Determination of harmful metal substances at the workplace by means of radionuclide X-ray fluorescence analysis (Zur Frage der Bestimmung metallischer Schadstoffe am Arbeitsplatz mit Hilfe der Radionuklid-RSntgenfluoreszenzanalyse). Meier H.. Unger E. Staub, Dusseidorf, Germany (Fed.Rep.), Sep. 1975, Vol.35, No.9, p.321-326. Illus. 117 ref. (In German) Study of the possible application of this method, above all for determination of cadmium in air. and literature survey on modes of sampling, principles of the method, and equipment. The method, which is suitable for determination of harmful substances in the workplace air, has the following features: simul taneous determination of several elements: rapidity; simple preparation of samples; good sensitivity. 1049541 CIS 76-754 Toxic skin reactions caused by tributyltin oxide (TBTO) in socks. Molin L, Wahlberg J.E. Berufs-Dermatosen. Aulendorf i. WiirtL. Germany (Fed.Rep.), 1975, No.4, p.138-142. Illus. 7 ref. (In English) CIS76-74S Occupational hygiene during production of Tobias acid with respect to the carcinogenic hazard (Gigiena truda v proizvodstve amino-tobias kisloty $ toCki zrenija kancerogennoj opasnosti dlja robotajuiiih). Lipkin I.L, Genin V.A Gigiena truda i professionai'nye zabolevani ja, Moskva, USSR, Mar, 1975, No.3. p.5-9. (In Russian) Removal of 3-naphthylamine from 2-amino-1-naphthalenesulfonic acid causes the latter to lose its carcinogenic properties completely. One of the Report on an epidemic of acute dermatitis of the feet in 70 soldiers whose socks had been disinfected with a solution containing an excessive concen tration of tributyltin oxide (TBTO). Patch tests carried out with solutions con taining 0.1% TBTO concentrations gave 62% positive reactions, whereas only 3% positive reactions occurred with 0.01% TBTO concentration. Concur ring with previous research, the authors consider this acute dermatitis to be due to the primary irritant properties of TBTO, and advise against its use as a disinfectant for textiles on account of the narrow span between the optimal ./ '-mL 93 CUSAROSS 02599 pane suiiune. /\ commentary on me oeciee explains me reasons lor toe prom otion (in particular, the carcinogenicity of this substance). loaeeai most effective means of preventing tormation of p-naphthylamine in 2-ami no-1-naphthalenesulfonic acid production is to ensure complete sulfonation of the 2-naphthol. The article reviews research and the measures taken in CIS 76-743 Hazards of chronic exposure to halothano for operat the Soviet dye industry to eliminate the carcinogenic hazard (modification of ing theatre personnel (Danger de ( exposition chromque & I'halothane pour the filtration unit, centrifugal separators, washing units, etc. to avoid all direct le personnel dun bloc opGratoire). Desbaumes E,, Ducel G.. Imhoff C.. Rouge J.C. Annates de I'anesthisiologie franpaise, Boulogne, France, Oct. 1975, contact; periodical examinations of exposed workers)./ . , (04924) 5,2,6 c-/i''(< ^Vol.16, No.6, p.437-445. Illus. 20 ref. (In French) /CIS 76-749 Gastric function in chronic vinyl chloride poisoning Results of an occupational hygiene survey in an operating theatre of a Swiss 1/ (Funkcional'noe sostojanie ieludka pri hroniieskoj intoksikacii vinilhloridom). "lospital. prompted by the incidence of malaise and fatigue in personnel ex posed to vapours of halothane (2-bromo-2-chloro-1,1.1-trifluoroethane). Continuous measurement of the halothane concentration in air yielded aver Vajsman V.D., Stulova EA. Gorjaieva LA.. Zdaneeva G.S. Gigiena truda iprofessional'nye zabotevanija. Moskva. USSR, Mar. 1975, No.3, p.20-23.9 ref. (In Russian) age values of 5-30ppm, with peaks of 50-70ppm, Inhalation of halothane was confirmed by the presence of brominated metabolites in the urine (aver age 14.59mg/l in female anaesthetists). Halothane in the ambient air may thus be responsible for the symptoms. To prevent the risk of poisoning, in the absence of a ventilation system renewing the air more than 20 times/h, a device to exhaust the halothane vapours should be installed, or they should be removed by recycling the polluted air via an active carbon filter. A perma nent monitoring system incorporating an audible and visual alarm is recom Results of gastric function studies in 69 workers suffering from chronic vinyl chloride poisoning and in 12 workers engaged in production of vinyl chloride. The authors observed changes in secretion of gastric juice, free acid, pepsin and mucoproteins. The degree of these changes corresponded to the severi ty of nerve function disorders in poisoned subjects. The authors suggest that chronic vinyl chloride poisoning could be due to a disorder of the hypothala- mo-pituitary axis. (04925) mended. 1049011 CIS 76-744 Value of urine tests in determining exposure to poi sons (Valeur des tests urinaires dans la determination de lexposition aux toxiques). Lauwerys R. Cahiers de midecine du travail - Cahiers voor arbeidsgeneeskunde. Gerpinnes, Belgium, Oct, 1975. Vol.12, No.3, p.175-179. (In French) The first part of this study deals with organic substances. Since these are very rapidly metabolised, urine samples should be taken during exposure, or as soon ss possible afterwards. Review of metabolites corresponding to: aro matic hydrocarbons (benzene, toluene, xylene, styrene): halogenated organic compounds (trichloroethylene, tetrachloroethylene, trichloroethane, vinyl chlo ride): other organic compounds (dimethylformamide. methanol, ethyleneglyc ol and its monomethyl ether, phenol, nitrobenzene, aniline). The normal val ues of these metabolites and values corresponding to a given level of expo CIS 76-750 Particular clinical features of occupational diseases in workers engaged in triaryl phosphate production (Nekotoryc osobennosti kliniki professional'nyh zabolevanij u raboiih zanjatyh proizvodstvom triarilfosfatov). Ajzenitadt V.S. Gigiena truda i professionalnye zabolevanija. Moskva, USSR, Mar. 1975, No.3, p.23-26. 5 ref. (In Russian) Examination of 251 workers employed in production of triaryl phosphates showed chronic poisoning by these compounds to be characterised by neuro logical symptoms accompanied by chronic gastritis with secretory insufficien cy and inhibition of plasma cholinesterase activity. The symptoms of the first stage of poisoning (after 2-3 years' exposure) are a perivascular form of auto nomic polyneuritis and an autonomic neurasthenia syndrome or disturbance of vascular tone. In the second stage there is progression to toxic encepha lopathy with a hypothalamic syndrome and polyneuritis. Recommendations for treatment (04926) sure are reproduced. The second part is devoted to determination of inorgan ic poisons: arsenic, cadmium, chromium, fluorine, lead, manganese, inorganic mercury. Precautions necessary for certain determinations. Examinations to be performed in the case of certain occupations (garage personnel, furniture manufacturers, etc.). (04907) CIS 76-751 Clinical picture of chronic poisoning in workers em ployed in nitron production (K klinike hromceskoj intoksikacii v proizvodstve nitrona). Sustov V.Ja,. Mavrina E.A, Gigiena truda i professional'nye zabolevanija, Moskva, USSR. Mar. 1975, No.3. p.27-29.7 ref. (In Russian) CIS 76-745 Blast furnace gas (Les gaz de hauts fourneaux). Goullard. Re gional Sickness Insurance Fund for Northern France (Caisse rdgionale |'assurance maladie du Nord de la France), 11 boulevard Vauban, 59024 Lille ledex, France. May 1975.9p. Gratis. (In French) Examination of 390 workers in the synthetic fibre industry exposed to acrylon itrile, methyl acrylate and sodium thiocyanate brought to light functional disor ders of the central nervous system, gastrointestinal tract, liver, cardiovascular system and haematopoietic function. In some cases these disorders were ac companied by symptoms such as nystagmus, olfactory impairment, etc., and After describing briefly how blast furnace gas is formed, the author describes the circumstances in which it can leak out (hazard during normal operation and. above all, hazard due to wear). The chief hazard is due to the fact that characteristic signs of diencephalic disturbance. Prolonged exposure to acry lates inhibits enzyme activity, with resulting biochemical disturbances. Re commendations for treatment (04927) this gas has a high CO content Description of the poisoning syndrome, which may be progressive or chronic. Lifesaving and first aid methods, safety engineering (at the planning stage, during construction (quality and strength of wedded joints of blast furnace shell, of refractory brick lining, accessibility and manoeuverability of valves) and during production); personal protective equipment (compressed air fed respirators); staff information. 10491 u 1/CIS 76-752 Determination of urinary atrolactic acid as a test of amethylstyrene exposure (Opredelenie atrolaktovoj kisloty v moe kak 6kspozicionnaja proba pri vozdejstvii Ct-metilstirola). Ajzvert LG. Gigiena truda / professional'nye zabolevanija. Moskva, USSR. Mar. 1975, No.3, p.38-41. 2 ref. (In Russian) CIS 76-746 Toxicity of hydrazine for animals of various ages (Toksiinost' gidrazina dlja fivotnyh raznogo vozrasta). SavCenkov M.F., Benemanskij V.V., Baianov O.V. Gigiena i sanitarija. Moskva, USSR, Mar. 1975, No.3, p.29-33. lilus. 3 ref. (In Russian) Results of studies in animals and man on the quantitative conversion of a- methylstyrene (intake by inhalation or via the skin) to atrolactic acid. Descrip tion of polarographic determination of the acid in the urine, modified to per mit a reading by spectrophotometry. Determination of atrolactic acid as a test of exposure to a-niethylstyrene is recommended. (04930) Results of comparative studies in white rats to determine the toxic effects of hydrazine vapours in relation to age. Young animals were most severely af fected by acute exposure, while long-term exposure caused slightly severer bone marrow changes in the older animals. (04922) CIS 76-747 Experimental studies on the organic effects of ammo nia under varying conditions of exposure (Eksperimental'noe issledovanie vlijanija ammiaka na organizm pri razliinyh reiimah vozdejstvija). Ivanov N.G., Pliskovskaja G.N., Kljaikina A.M., Korotid LP,, Germanova A.L Gigiena i sanitarija. Moskva, USSR. Mar. 1975, No.3, p.38-41.10 ref. (In Russian) The earliest disturbances observed in animals exposed to ammonia under va rious condition^ involve the respiratory tract. When the concentration is in creased progressively, respiratory effects and those on olfactory function oc cur later and follow a more chronic course than when the concentration is constant Thus progressive increase of the ammonia concentration is more deleterious to health than prolonged exposure to a constant concentration. (04923) CIS 76-753 Determination of harmful metal substances at the workplace by means of radionuclide X-ray fluorescence analysis (Zur Frage der Bestimmung metallischer Schadstoffe am Arbeitsplatz mit Hilfe der Radionuklid-Rontgenfluoreszenzanalyse). Meier H.. Unger E, Staub, Dusseldorf, Germany (Fed.Rep.). Sep. 1975, Vol.35, No.9. p.321-326. Illus. 117 ref. (In German) Study of the possible application of this method, above all for determination of cadmium in air, and literature survey on modes of sampling, principles of the method, and equipment. The method, which is suitable for determination of harmful substances in the workplace air, has the following features: simul taneous determination of several elements; rapidity: simple preparation of samples: good sensitivity, (04954) CIS 76-754 Toxic skin reactions caused by tributyltin oxide (TBTO) in socks. Molin L, Wahlberg J.E. Berufs-Dermatosen, Aulendorf i. WurtL. Germany (Fed.Rep.), 1975, No.4, p.138-142. Illus. 7 ref. (In English) |CIS 76-748 Occupational hygiene during production of Tobias ^cid with respect to the carcinogenic hazard (Gigiena truda v proiz- fodstve amino-tobias kisloty s toiki zrenija kancerogennoj opasnosti dlja robotajuSiih). Lipkin I.L. Genin V.A. Gigiena truda i professionalnye labolevamja, Moskva. USSR, Mar. 1975, No.3, p.5-9. (In Russian) Removal of 3-naphthylamine from 2-amino-1-naphthalenesulfonic acid causes the latter to lose its carcinogenic properties completely. One of the Report on an epidemic of acute dermatitis of the feet in 70 soldiers whose socks had been disinfected with a solution containing an excessive concen tration of tributyltin oxide (TBTO). Patch tests carried out with solutions con taining 0.1% TBTO concentrations gave 62% positive reactions, whereas only 3% positive reactions occurred with 0 01% TBTO concentration. Concur ring with previous research, the authors consider this acute dermatitis to be due to the primary irritant properties of TBTO, and advise against its use as a disinfectant for textiles on account of the narrow span between the optimal / (c CUSAROSS 02600 93