Document 3eqZBEvxL5VJmDjOyXmXxN43O

A zinphosmethyl 113 iv I'unc- sufficient at ihis time to set an exposure stan dustrial Materials, p. 440. New York: .i-s may dard (other than zero) which could assure Rcinhold Book Corporation, 1975. Ivspnea, prevention of mesothelioma in all workers, 3. Joint ACGIH-A1HA Aerosol Hazards since the disease may occur following a very Evaluation Committee: Background doc Irpcnils limited exposure 20 to 30 years earlier.1 umentation on evaluation of occupation ihe Cigarette smoking is strongly implicated as al exposure to airborne asbestos. Am. I expo- a cocarcinogen among asbestos workers.* Ind. Hyg. Assoc. J.,36:91, 1975. disease The incidence of bronchogenic carcinoma 4. National Institute for Occupational in nine among nonsmoking asbestos workers is not Safety and Health, U.S. Department of iv as 13 significantly greater than that of nonasbestos Health, Education and Welfare: Criteria lly, Ihe workers, while asbestos workers who smoke for a Recommended Standard. Occupa o io 40 have a much higher incidence* Calculations tional Exposure to Asbestos, (HSM) -.I'CSIOS.3 suggest that cigarette smoking asbestos 72-10267. Washington, D.C.: U.S. Gov ttresses workers have approximately eight times the ernment Printing Office, 1972. l;l In its risk of developing lung cancer compared with 5. A.C.G.I.H.: Asbestos. Documentation )> inability other smokers.1 of the TLVs for Substances in Workroom scon or y:itil|i blood The TLV was established to protect against Air. ed. 3, pp. 17-19. Cincinnati, 1976. asbestosis and reduce to an acceptably low risk the development of neoplasms.5 Supplemental thclio- Diagnosis: Signs and symptoms include 6. Selikoff, I. J., Churg, J., and Hammond, ;j- nasally localized pleural thickenings, which may be E. C.: Asbestos exposure and neoplasia. ii . tresses come radiopaque through calcification; re JAMA, 188:22, 1964. jfi leclum strictive pulmonary function; rales, dyspnea, 7. Selikoff, 1. J., Hammond, E. C., and. asbes- cyanosis, dry cough, and finger clubbing. Churg, J.: Asbestos exposure, smoking > n. 1967. Differential. Diagnosis: Differentiate from and neoplasia. JAMA,204:106,1968. >, Mini ex- other diseases which are associated with dif 8. Selikoff, 1. J., Hammond, E. C., and >.ii.- male fuse infiltration of the lungs: Hamman-Rich Seidman, H.: Cancer risk of insulation nvies-- syndrome, Lofller's syndrome, fungus infec workers in the United States. Biological i '<<). and tions, sarcoidosis, scleroderma, and other Effects of Asbestos, p. 209. Lyon: WHO ! .incem- rare types of diffuse interstitial fibrosis. International Agency for Research on ' ill.- cases ; Differential diagnosis of pleural mesothcli- Cancer. 1973. i'..l King- ! oma should include inflammatory pleurisy, 9. Wright, G. D.: Asbestos and health in ipalion- : primary lung cancer, and the presence of met- 1969. Am. Rev. Rcspir. Dis., 700:467, i with as- ; astatic disease from a primary tumor else- 1969. yllix were j where in the body.1* 10. Stumphius, J., and Meyers, P. B.: Asbes >i limitation Special Tests: Radiography, tuberculin skin . tos bodies and mesothelioma. Ann. Oc- M.mparcd I test, and sputum culture should be per- cup. Hyg., 77:283, 1968. number V formed. 11. Champion, P.: Two cases of malignant I iMipula- { Treatment: None is specific. mesothelioma after exposure to asbestos. | Medical Control: Preplacement and annual Am. Rev. Respir. Dis., 703:821, 1971. | physical examination, with emphasis on the 12. Legha, S. S., and Muggia, F. M.: Pleural f pulmonary, cardiovascular, andgastrointes- mesothelioma: clinical features and thera i tinal systems; chest roentgenograms; lung peutic implications. Ann. Intern. Med., j function tests to include FVC and FEV (I 87:613, 1977. l sec.); sputum cytology. i 1 f References AZINPHOSMETHYL | Principal (CH30)2P(S)SCH2(N3C,0) I 1. Department of Labor: Occupational ex- 1977 TLV 0.2 mg/m5 j posure to asbestos. Federal Register, 40:47652,1975. Synonyms: 0,0-Dimethyl S(4-oxo-l ,2,3 i 2. Sax, N. 1,: Dangerous Properties of In- -benzotriazin-3(4H)-ylmethyl) phosphoro- I ~Pl r GLEASON-000061