Document 3NpzrGE1MVbZdOw7e8wO8oaDa

FINAL REVISED PRO-GRAM December 16, 1998 Benzene State of the Science Workshop University of Ottawa Institute of Population He~lth Montpetit Hall, Room 201 8:30am 8:45am Welcome Overview of the Benzene Problem Daniel Krewski, Rapporteur Robert Snyder Benzene Metabolism and Genotoxicity, Bob Sonawane, Chair 9:15am 9:35am 9:45am 10:00 am -10:15 am 10:35 am -10:45..am 11:00 am Benzene Metabolism Break Benzene-induced Genotoxitity Implications for Ri-sk Assessment David Ross -Paul Schlosser, Discussant Open Discussion John Whysner David East-mood, Discussant Open_Discussion Daniel Krewski, Rapporteur Toxicity & Leukemogenesis, Patrick Beatty, Chair 11:15 am 11:35 am 11:40 am 12:00 pm Value of Transgenic-models Lunch: Rendez-Vous Restaurant John French Robert Snyder, Dis-cussant" Discussion BP-00011659 .. FINAL REVISED PROGRAM December 16, 1998 Benzene State of the Science Workshop University of Ottawa Institute ofPOpulation Health Montpetit Hall,_ Room 201 Toxicity & Leukemogenesis, Patrick Beatty, Chair (Continued) 1:10pm 1:3.0 pm 1:50pm 2:00pm 2:15pm 2:35pm 2:45pm 3:00pm -3:15pm 3:35pm __3:55pm 4:05pm 4:25pm 4:40pm 5:00pm 7:00pm Hematotoxicity Modeling Patrick Beatty Melvin Andersen Secondary Leukemogenesis Richard Lar..son Armand Keating, Discussant Discussion Hemato_toxicity & Leukemogenesis Azra Raza Deborah Laskin, Discussant Discussion Break Mechanism of Leukemogenesis -Richard Irons GeorgeKalf Martyn Smith, Discussant Discussion Implications for Risk Assessment -naniel Krewski, Rapporteur Discussion Conclusion Dinner: Rendez-Vous Restaurant Dinner speaker: Ronald Worton, University of Ottawa BP-00011660 ------- - - - FINAL-REVISED PROGRAM December 17, 1998 Benzene State of the Science Workshop University of Ottawa Institute of Population Health Montpetit Hall, Room 201 Benzene Induced Leukemia: Human Studies, Carol Henry, Chair 8:30am 8:50am 9:10am 9:30am 9:50am 10:10 am -10:30 am .11:15 am 11:55 am 12:10 pm NCI/Chinese Epidemiology-Study Richard Hayes I Martha Linet Insights from Petroleum Studies Robert Schnatter Biomark4!rs of Leukemia Risk Martyn Smith HEI Biomarker Research in China Martha Richmond New Initiatives for Epidemiologic Research Otto Wong Break Discussion Panel Jack Siemiatydd Pierre Band David Bayliss Bob Sonawane Open Discussion Implications for Risk Assessment Daniel Krewski, Rapporteur _Lunch: Rendez-Vous Restaurant BP-00011661 FINAL REVISED PROGRAM December 17,1998 Benzene State of the Science Workshop University of Ottawa Institute of Population He~lth Montpetit Hall, Room 201 Future Research to Improve Risk Assessment & Risk Management, Bernie Goldstein, Chair 1:00pm U.S. EPA Perspective 1:20pm Health Canada Perspective 1:40pm European Union Perspective 2:00pm California EPA Pers-pective 2:20pm Petroleum Industry Perspective 2:40pm Good Science for-Good Decisions; The NIEHS Perspective 3:00pm Open Discussion 3:45 pm Concluding Remarks 4:0ft pm Conclusion Bruce Rodan Bette Meek E. Dinant Kroese Lauren Zeise Patrick Beatty Geoffrey Granville Christopher Schonwalder -naniel-Krewski, Rapporteur BP-00011662