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Studies To Be Moved to 8(e) Docket EPA Submission Chemical/ Date Product Name Study Title Laboratory Study Study No. Date Study Type 0 4 /2 1 /2 0 0 0 KPFOS O ral (S tom ach Tube) D evelopm ental Toxicity S tudy o f P F O S in R abbits A rgus R esearch La bora torie s, Inc. 4 1 8 -0 1 2 0 1 /1 1 /1 9 9 9 H ealth Effects: D evelopm ental T oxicity 0 4 /2 1 /2 0 0 0 K PFOS; T-6246; FC-95 S ingle D ose Intravenous P haram acokinetic Study o fT 6 2 46 in R abb its. 3M E nvironm ental Laboratory S tudy #A M D T-042095.1 3M Technical AMDT0 4 2 0 9 5 .1 1 1 /1 1 /1 9 9 5 H ealth Effects: P harm acokinetic & M etabolism S tudies 0 4 /2 1 /2 0 0 0 PFOS; PFHS; PFOA' NEtFO SAA; FO SA; N-M eFOSAA; PFOSAA; M570; M556 F luorochem ical Exposure A ssessm e nt o f D ecatur C hem ical and Film Plant Em ployees M e d ica l Departm ent, 3M Company EPI-0006 0 8 /1 1 /1 9 9 9 H um an Data & Incidents: M edical S urveys, C linical S tudies, R eports or A lle g a tio n s o f W orke r o r C onsu m er Effects 0 5 /0 4 /2 0 0 0 DEA PFOS; FC-99 N ew Form ula; T2509 CoC Tw o W eek Oral R angefinding T o xicity S tudy o f T -2 5 0 9 C o C in Rats R iker Laboratories, Inc. 179RR023 0 2 /2 5 /1 9 8 0 H ealth E ffects: A cute T oxicity 0 5 /0 4 /2 0 0 0 KPFOS A cu te O ral T o xicity (LD5C) S tudy in R ats In te rn a tio n a l Research and D evelopm ent C orporation 137-083 0 5 /3 1 /1 9 7 8 H ealth Effects: A cute T oxicity 0 5 /0 4 /2 0 0 0 KPFOS 0 5 /0 4 /2 0 0 0 K PFOS; T-6295 P FO S : A Dietary' LC50 S tudy w ith the N orthern B obw hite W ildlife In te rn a tio n a l 104 W eek D ietary C hronic Toxicity and C arcinogenicity Study w ith PFO S Potassium S a lt In Rats Covance . . La b o ra to rie s, Inc. 454-103 6329-183 0 4 /2 6 /2 0 0 0 E nvironm ental Fate & T oxicity Data: A vian & O th er W ild life H ealth Effects: C arcinogenicity 'S tudies 0 5 /0 4 /2 0 0 0 K PFOS; T-6295 26 W eek C apsule Toxicity S tu d y w ith P F O S ; T -6 2 9 5 in C ynom olgus M onkeys (V o lu m e I a n d II) Covance L a bora torie s, Inc. 6329-223 0 4 /1 2 /2 0 0 0 H ealth Effects: C hem ical-T issue O bse rvatio ns 0 5 /0 4 /2 0 0 0 K PFOS; T-6295; T e lom er Alcohol; T e lom er A crylate; PFBS; PFHS _E xploratory 28-D ay Oral Toxicity S tudy w ith T e lom er A lcohol, T e lo m e r A crylate, PFBS, PFHS, and PFOS (p ositive co n tro l) By D aily G a v a g e In T h e R a t F o llo w e d by a 14/28 Day R ecovery P e rio d 3M E nvironm ental Laboratory (FAC T) F A C T -T O X 1 2 0 .3 0 6 /1 1 /1 9 9 9 H ealth Effects: S ubch ronic Toxicity 0 5 /0 4 /2 0 0 0 P erfluoroethylcyclo hexyl sulfonate D EA Salt; FC-90; T-2960 CoC A cute O cula r Irritation Test w ith T -2 9 6 0 C o C in A lb in o R a b b its S afety E valuation Laboratories, R iker Laboraties, Inc. 0880EB0598 0 2 /1 8 /1 9 8 1 H ealth Effects: D erm al/E ye Irritation Page 1 o f 3 3MA01220049 EPA Submission Chemical'/ Date Product Name Study Title Laboratory Study No. Study Date Study Type 0 5 /0 4 /2 0 0 0 PFOS Fiuorochem ical (F C ) Levels in N aive Rats - F u rthe r Investigation o f R at C how 3M T -6 3 1 6 .9 ; DT21 0 5 /1 4 /1 9 9 9 E nvironm ental Fate & T o xicity Data: O ther E nvironm ental Inform ation 0 5 /0 4 /2 0 0 0 PFOS Fiuorochem ical (FC ) Levels in N aive Rats, T -6 3 1 6 .9 3M Medical Departm ent, T o x ic o lo g y S ervices T -6 3 1 6 .9 0 5 /1 4 /1 9 9 9 H ealth Effects: P harm acokinetic & M etabolism S tudies 0 5 /0 4 /2 0 0 0 PFOS; PFHS; PFDS; PFO A PFOSAA; M556: M570; M463; M513 A n a ly s is o f F C s in S a m p le s o f C hildren's S era 3M Environm ental T e chnology & S ervices 0 5 /0 4 /2 0 0 0 P otassium pe rfluoroeth ylcyclo hexyl sulfonate; FC-98; T-2308 CoC A cute Inhalation T oxicity S tu d y o f T -2 3 0 8 C oC in the Rat B io/dyn am ics, Inc. F A C T -G E N 011 0 5 /2 1 /1 9 9 9 H um an Data & Incidents: M edical S urve ys, C linical S tudies, R eports or A lle g a tio n s o f W o rke r or C onsu m er Effects 78-7187 0 4 /1 2 /1 9 7 9 H ealth E ffects: A cu te T o x ic tty 0 5 /1 2 /2 0 0 0 PFOS; FOSA; PFOA; PFHS Q uantitative A n a lysis of FCs in E nvironm ental S am ples 3M E nvironm ental Laboratory (FAC T) FACT Gen021, Gen024, Gen030, Gen033 0 5 /1 0 /2 0 0 0 E nvironm ental Fate & Toxicity Data: G e n e ra l 0 5 /1 8 /2 0 0 0 FO SA; T-3421 A cu te O ral T o xicity S creen w ith T -3 4 2 1 in A lb in o R ats R iker Laboratories, Inc. 0883AR0287 0 1 /1 7 /1 9 8 4 H ealth E ffects: A cute T o x ic ity 0 5 /1 8 /2 0 0 0 N-EtFO SA 0 5 /1 8 /2 0 0 0 N-EtFO SA A D evelopm ental T oxicity S tu d y o f 313401 in R ats W1L R e se a rch La b o ra to rie s, Inc. P rim ary Eye Irritation 'P ro d u ct S afety Labs 157016 3871 0 5 /3 0 /1 9 9 7 H ealth E ffects: D evelopm ental T o x ic ity 1 1 /0 3 /1 9 9 5 H ealth Effects: D erm al/E ye Irritation 0 5 /1 8 /2 0 0 0 N -E tFO SA ; NEtFO SE A coho l; N-M eFOSE A cohol B io a c c u m u la tio n o f F C in T e nne ssee R iver Fish 3M Environm ental L a b o ra to ry 0 5 /1 8 /2 0 0 0 N -EtFO SE A lco h o l A b sorption and "B lotransform ation of N -ethyl FO SE and Tissue Distribution and E lim ination o f C arbon 14 after A dm inistration o f N -ethyl F O S E 1 4 C in Feed R iker Laboratories, Inc. 78-2740 0 5 /2 2 /1 9 7 9 Environm ental Fate & T o xicity Data: B ioaccum ulation/P ersi s te n c e 0 1 /1 9 /1 9 8 3 H ealth Effects: P harm acokinetic & M etabolism S tudies 0 5 /1 8 /2 0 0 0 N -E tFO SE Alcohol O ral (G avage) D evelopm ental T oxicity S tudy o f N -E tFO SE in Rats T -6 3 1 6 .7 ; 418-011 1 2 /1 7 /1 9 9 8 H ealth E ffects: D evelopm ental T o x ic ity 0 5 /1 8 /2 0 0 0 N -E tFO S E Alcohol O ral (Stom ach Tube) D evelopm ental T oxicity S tu d y o f N -E tF O S E in R a b b its Argus R esearch Labora torie s, Inc. 418-010; 6 3 1 6 .8 0 1 /1 1 /1 9 9 9 H ealth Effects: D evelopm ental T o x ic ity Page 2 of 3 3MA01220050 EPA Submission ChemicalV Date Product Name Study Title Laboratory Study No. Study Date Study Type 0 5 /1 8 /2 0 0 0 N -E tF O S E A lcohol; FM -3422 E valuation o f the B ioconcentration P otential o f FM 3422 3M E nvironm ental Laboratory (FAC T) 9970612623 0 8 /1 6 /1 9 7 8 E nvironm ental Fate & T o xicity Data: B ioaccum ulation/P ersi sten ce 0 5 /1 8 /2 0 0 0 N -E tF O S E A lcohol; T-5874 D eterm ination o f the Partition C oefficie nt (no cta nol/w ater) o f T -587 4 by high pe rform ance liquid chrom atography (HPLC) NOTOX 121275 0 4 /0 7 /1 9 9 4 E nvironm ental Fate & T o xicity Data: B ioaccum ulation/P ersi sten ce 0 5 /1 8 /2 0 0 0 N -E tF O S E A D eterm ination o f P hysicoC hem ical P roperties o f S am p le D-1 M itsubishi C hem ical Safety Institute, Ltd. 4B 223-4B227 0 2 /1 4 /1 9 9 6 E nvironm ental Fate & T o xicity Data: B ioaccum ulation/P ersi s te n c e 0 5 /1 8 /2 0 0 0 N-EtFOSEA; T6322 T w e n ty-e ig h t-d a y R epeated D ose O ral T o xicity S tudy o f S a m p le D-1 in R a ts, T -6 3 2 2 Bio-M edical R e s e a rc h L a b o ra to rie s B M R 143C 0 2 /1 6 /1 9 9 3 H ealth Effects: S u b ch ro n ic T o xicity 0 5 /1 8 /2 0 0 0 N -M e F O S E A lcohol; FM -3925 D istribution C oefficie nt o f FM 3 9 25 in N -O cta n o l W a te r 3M Environm ental Laboratory (FAC T) 9970012600 0 1 /1 0 /1 9 7 9 E nvironm ental Fate & T oxicity Data: B ioaccum ulation/P ersi sten ce 0 5 /1 8 /2 0 0 0 N -M eFO S E A T5869 D eterm ination o f the Pollution C oefficient (nocta nol/w ater) o f T-5869.4 by high p e rform ance liquid chrom atography (HPLC) NOTOX T -5 8 6 9 .4 0 4 /0 7 /1 9 9 4 E nvironm ental Fate & T o xicity Data: B ioaccum ulation/P ersi sten ce 0 5 /1 8 /2 0 0 0 PFOSAA; T-3290 CoC A cu te O ral T o xicity S creen w ith T -3 2 9 0 C o C in A lb in o R a b b its R iker Laboratories, Inc. C882AR0362 1 1 /0 5 /1 9 8 2 H ealth E ffects: A cu te T o x ic ity 0 5 /2 5 /2 0 0 0 NH4 PFOA; T3974; FC-126 P rim a ry E y e Irrita tio n In Rabbits, T-3974 ' H azelton L a b o ra to rie s 61005209 0 1 /1 4 /1 9 8 7 H ealth Effects: D erm al/E ye Irritation 0 5 /2 5 /2 0 0 0 P F O A em ulsifier; T-6564; FC-1015 P rim ary Eye Irritation/C orrosion S tudy of T-6564 in R abbits (O E C D G uidelines) C orning H azelton Inc. CHW 60504574 0 9 /0 5 /1 9 9 6 H ealth Effects: D erm al/E ye Irritation Page 3 o f 3 3MA01220051