Document 3JL3LVRXazO7eKbgveGwQw8jO

FILE NAME Manville JMA DATE 1950 DOC JMA341 DOCUMENT DESCRIPTION Memos Letters & Study Proposal - Saranac Laboratory Confidential } : wa PE COPY 23852 General Headquarters August 17 1950 fi G. K. Foster - Montreal Cancer Research Please excuse the delay in commenting on was due to my inability to find a former liminary fashion the idea that was to be your letter of July letter which set up followed 28 which in pre- Attached is a copy of a letter of June 19 from Dr. K. W. Smith to C. M. MoGaw which I am sending to you inamuch as it appears that you did not receive a copy This was Dr. Smith's suggestion as to the setting up of the program and you will note he was to receive from Dr. Vorwald and from Dr. Lanza separate suggested programs on the basis of which recommendations would ultimately be made to the C. A. M. A. Dr. Smith may have additional information since he wrote this letter I expect to see Dr. Lanza in a day or two and will ask him what he knows e e about it as of this time and will pass on to you any information I may cohen get Pe Qe We should like to be kept in touch with the developments and should hope we could have it reviewed with Dr. Lanza before a program is undertaken provided that is considered the proper approach in the matter You mentioned that we are and inasmuch as Dr. Lanza it would be helpful if we to bear a considerable is advising with us on could have his advice portion of the such problems expense I think I have not discussed this with Mr. Fisher recently but I believe his viewpoint is the same as that I have expressed here ano ee: A. R. Fisher Confidential on ~ FILE COPY 23851 23851 23851 General Headquarters August 21 1950 |/ an G. K. Foster - Montreal Cancer Research with my letter of August 17 replying to yours of July 28 I sent you a copy of Dr. Smith's memo of June 19 to C. M. MoGaw In his letter Dr. Smith mentioned that Dr. Lanza and his group would prepare a program for experimental studies and that Dr. Vorwald at Saranac would do likewise Upon receipt of the two progrms it was stated that he and Dr. Cartier would then be in a position to make recom mendations that might guide the Q. A. M. A. It was understood that information would be supplied us here about the subject too I have since seen Dr. Lansa who apparently has not yet sent in his suggested program and he doesn't know whether Saranac has His is going to Saranac to a meeting of the Board of Directors within the next few days and will have the opportunity to discuss the matter with Dr. Yorvald When A. R. and I discussed this today he mentioned that there may or may not have been time for a study of the programs to have been made so that a definite recommendation as to what should be done might be made but you could at least report progress at this time in case it hasn't yet resobed that stage Perhaps Dr. Smith has further information he is getting a copy of this memo he can tion that he may have now that pass I don't know of and since on to you any other informa- 001 A. R. Fisber K. W. Smith M. D. Asbestos C. M. Mo>uw Asbestos A. J. Lanza M. D. AJLI The meeting of the Q. A. M. A. I judge your suggested program you said here the other day is to be about can be sent in September 20th shortly from what JPW Vw } These studies can be considered as indispensable preliminaries to any inhalation study planned on the same material since they might very well provide a basis for selection of materials for use in the more elaborate inhalation studies These the Institute could get under way any time after September 1st Such studies would involve exploratory implantation and injection of a group of materials to be determined jointly using technics as now employed by Dr. William E. Smith Such a study which would include a number of materials would come to about 10,000.00 for a one ye r study Such a project would be carried out under a contruct of the type enclosed ; hi , In summary 1 We suggest that the desirability of en : epidemiological study be determined on the basis of a visit to your plants 2 that definite plans for an inhalation study be deferred i ! _ . for three or four months 3 that screening studies by implantation and injection be started immediately - aoe Sincerely yours , . 3 * A.J. Lanza M.D. Chairman Institute of Industrial Medicine AJLIlo incl C.C Mr. J. P. Woodard CONFIDENTaIy, C. Me. McGaw Hospital August 1950 1940 Pulmonary Malignancy that Dr. Lanza parts with received Dr. Lanz the Cartier Cartier I that the the 1 - An epidemiological or 12 a Animal experiments statistical study Animal Inhalation consisting : experiments Implantation or injection ZI still believe that the statistical statistical study can be authority authority and thus that more acceptable to various groups this Province Province Province ed Also believe that the best results from inhalation inhalation studies will obtain- inhalation Saranac Laboratory Studies will he obte^'ir~ Concerning Concerning Concerning Concerning The contract appears The contract unfavorable . unfavorable little However However fail fail Company which already already see how they can ^' interests and Morewether than anything unfavorable unfavorable Morewether Heuper Heuper and Heuper, than that KWS CO- K. G. G. Lindell Foster Montreal Kenneth W, Smith, M.D,  ' " ..... Confidential ' . . ' " ; September 1 1950 A. Fisher CO 820s i. a Industrial Hygiene > Asbestos Asbestos and Lung Cancer , ; . - Dr. > and Dr. Cartier and Dr. Smith were later in Saranac Vorwald the matter of whether asbestos produces were here in New York several discussing with Dr. Lanza and the proper program that would lung canoor _ months ago with ' determine and undertaken later be was to suggest to Dr. Cartier Dr. Smith what he thought .- |. Dr. Lanza Vorwald was to do the same It r. would be the best approwhat aandcDh r. = determined what program would be was * my the made Dr. the - Attached is copy of report Lansa to two * doctors copy by this report +3 After you have had a chance who can in -"s*end it to Hugh Jackson to review would you please turn give to me oe a Ce Oh, tf of i seg yr die eae : i , wo 1 . u . , . . o a a 001 H. M. Jackson . bow. v a 1 ee + : e ae ae . . i ar . < e - tobe - . . + 28 ee oe - aa : : eer . . a ant 4 , . Pa a , Mouse # : . + hae % a . . we : wn" , fe n : . q a r . to. on ' COPY - ; a ?, a oe ef 8) 2 Ta A . : wpe -. CONFIDENTIAL h%e: ry : fo . is . . . ate . on, 2384823848 . eo! - 3 : \ che 8 . Pa We, 16 oe re og . el CoM : oy me lo September 25 1950w':ey aan oS oe : . of rs et . oe ove . Pulmonary I - . re . rs , . oo Malignancy - .. st : . . . an * Dr. ve oo 7 te Tek te a: . ae it ot % . . iia . .. Cartier Thursday Thursday night Saranao and to went last Dr. * Paul I on Friday we dis- oussed this whole program and the Saranao Laboratory proposal with Dr. Vorwald presented Saj"turday proposal morning we went to Montreal and the Saranac and our recommendations | to 0. K. Foster ee .. research should followed of It er eee is our belief that two lines be The first is - wh the statistical study previously mentioned We believe that this should be carried out by a Canadian possibly with the help of some recognized United States statis. tician contacted Dr. O. H.Warwick Director of the National Cancer Institute of Canada st * is a personal friend of mine and I have him asking for his views Do : possiWbalrewick early and Dr. fi second ofresearch vas tTn he - help in this statistical survey Cartier and I are to meet in Montreal or here inAsbestos in October line recommended the of ae a institution animal inhalation experiments _|; at Saranac the results be coordinated with all the pathological:. my;experimental clinical radiological and engineering information available in oe Saranac The Trudeau Foundation hasjust received a grant for cancer research i program inhaled dusts part cancer beryllium 2 lung fifth by form of caused 73 and are conducting inhalation experiments with aluminum silica iron and ., If the asbestos experiments are approvedthey a will this iia of 2 ws , Mr. Foster plans the to summarizetheprogramsandmake his recommendations to the Q.A.M.A. at October F meeting oe ae Ln \ ea ye wot ' . an, te i . > oe aa e . i oo . . +e tee oe os 2 . ou t aan wl ' OY ee ok sof : . ~ . lle . ~ . . 2 oe a = at r . . ~ ae Me ae 1 ayer vveey naray ane fh War en : 8 i} es ra . Sy . . oa 2 tae fo eg? RY . > & we we . + CONFIDENTIAL CONFIDENTIAL date agar Sade gifs, to Saad bk Le C. M. McGaw Hospital i Septembe2r5 1950 Pulmonary Malignancy ~ Dr. Paul Cartier and I went to Saranac last Thursday night on Friday we discussed this whole program and the Saranac Laboratory proposal with Dr. Vorwald Saturday morning we went to Montreal and presented the Saranac proposal and our recommendations to G. K. Foster study It is our belief that two lines of research should be followed The first is the statistical previously mentioned We believe that this should be carried out by a Canadian possibly with the help of some recognized United States Dr. O. H. Warwick Director of the National Cancer Institute of statistician friend of mine and I have contacted him Canada is a personal asking for his views and possible help in this statistical survey Dr. Cartier and I are to meet Dr. Warwick in Montreal or here in Asbestos early in October ad | aa and The second line of research recommended was the institution of animal inhalation ex- periments at Saranac the results to be coordinated with all the pathological ex- perimental clinical radiological engineering information available in Saranac The Trudeau Foundation has just received a grant for cancer research and are conduct- ing inhalation experiments with aluminum silica iron and beryllium If the asbestos experiments are approved they will form a fifth part of this of lung cancer caused by inhaled dusts program Mr. Foster plans to summarize the programs and make his recommendations to the Q.A.M.A. at the October meeting . . tive - oa en oot ; - * Cre COEe oo Carte . cents ad 6 wee a io 7 Ta Ge 4, e be - coy _ KWS oo. Kenneth W. Smith M.D. COPY to A Lanza ee 1 oe ' ee ee or on ee -HMJ -HMJ -HMJ 10/9/50 ) DreAL 77" Se Lemma FOR Industrial Medical - Dr. Lansa . Dr. Institute Lansa a : fF New York University 477 First Avenue Avenue York Medicine 3-00 * 7 Center ~ Belevue btco oes __ aS 2 . proposal Cancer investigation ve Asbestosis attached Asbestosis and ceme with Pulmonary cas Before do wonder on ee Dear woe | Attached Attached investigation investigation investigation investigation me is a attached | Before you will review prepared by ) prepared Saranac which latter of Cancer October Art Cemarh from from Art TEE ree I . ty . mt givanyethinygofuurrthetrhoaubgohuttsthis wonder re. a When 1 I'll I'll mils away on needed week next vacation . : vu: when when Iget back hope a to ; ~ to hear Waukegan your to :, back ge Pog also Ta FOR aatiopgte you about sets trip. ; tas Sas ae ee fos ite + ew . ------ ---- -- -- -- -- FILE COPY Qabestoa 23837 October 1950 1950 Institute Industrial Lanza N.Y. Bellevue 1477 First First Bellevue Avenue York Dear Dear Medicine oN 7 y Tle PulmonaryMalignancy Attached foryour information is a ' of of Dr. K. Smith's letter let er copy of September 25to oe Me. Mr. C. McGaw subject 7 - a Enclosure ae . bes : Jackson ba : Jackson enc enc o : vy . 73 i s 4 7 : ons . 4 ran ale . . . nw Py : *. rea . Fs " - a " a Me i Ud [ [ , if Se, ca | | s+, Confidential ee eo | 4 , aa A. R. Fisher 2. a i * DEDE EE COPY . os October 20 1950 ' ve - c ra : o. 3 . . +.os Solesadal U Bt nyt Sut fale st 0 ls 3 Asbestos and Pulmonary Cancer Pe Fee Maret ye as Here sent the me copy of the Proposal dated September 21 Attached also is George Foster's report 1950 that Dr. Vorwald .... to the Q. A. M. dated Dae ./ 1's September 25 1950 which he had sentto you ; - A. _ >> wits: : _. -. +2 The main points were covered marginal day and I have made to you Some items were : notes when you Dr. Lansa and I discussed this yesteri in both booklets that may be of interest an re 7 wo he =. the epidemiological study ey yo - 7 1 - Make best possible by personnel well oe qualified in this field Desirable to have this precede Saranas roo ; | ee ' dust studies if possible but not necessary Dr. Lanza Dr. E. K. Hammond is known to says be good . a oe re | be well estimates years beyond might to on 2 It the first and - owe:| 2 second Saranae estimates the possibility of a year Fo 1d a'-3 program Doubtless these years would not be any more expensive '7 the second _r; a2, than year at 10,000 ... . 2. 4 oe ie 4 ' . a a: L ie ot .. " re a! ae fe Under about the we LES 3 Item 15 pa1g 1 e in the Saranac Proposal there is the ~ v tas.+ usual stipulation about publicatioofn the results This appears .. yet if Fie ., to be all right but it would be desirable representatives ,. .. Sy.'47 from Saranac would not make talks before groups bringing out doe so aan investiga invtesi tigo atinon that mA is not yet ready for Co te rg! eRe: possibly cannot hae hoa anpdublication As you recall this has been done in the past CO, be this % prevented cl a , ie a Coes 2 a> itthast ethweiistmhsour normtahlhee on ofputting out interfere good Ley a As to Mr. Foster's report --., propaganda is a one _ ments made on the other side . I w., , lecture at'medical schools not not so frequently to that idea of truthful in order to counterascomte of the wild state- =... presume speaks having our doctors ts mE would be only certain occasions and a . business NA . oe Le FR. . ge cee sg yoy ata ar Dee , og ee ohe@ chest agreed 1 *, Dr. Lanza with my thought that we would well a. - institute for industrial disesses to avoid forming an a *" with other mining the obvious reason that associations for tt, |. we have minor problems might become ~/*, fied with relatively and identi- in the industry in some very serious problems ay general where workmen eres i other ailments pg ft are dying of silicosis siderosis of this kind workmen oo fi Pn nn oar . eas ws valit wf ey eae ao . .o - geste. iheee he ~. i , WBea M. Oy . det nd Sy Jackson oy Les . . . yy. . 7, fle ra we wo. 2 . *, . ia t October 20 1950 4 Pose . Dr. A. J. Vorwald Director : mo The Saranac Laboratory Saranac Lake New York Dear Art a >: . Thanks for sending me a copy of the proposed program for the investigation of Asbestos and Pulmonary Cancer which ,, came while I was way with your letter of October 4 ' muchthought by given ee This subject is being not only o> urselves but as you know by the other members of the industry Doubtless Dr. Smith or Dr. Cartier has wholetold you be discussed with the group as a that this is to . re I believe there will be decisions looking toward the of inauguration a | in program the very near future r <d _ 4 f " bo | A. R. Fisher . am ee. ele, | ; . 5 on Me oe. .