Document 37r6OgGxNqM5JqDe7K92b3yaO

FILE NAME Manhattan RBM DATE 1936 Nov 20 DOC RBM106 DOCUMENT DESCRIPTION Letter to the Saranac Laboratory from Vandiver Brown Stating The Funders Should Decide on any Publication of Privately Funded Research November 20 1936 LeRoy U. Gardner M. D. The Saranac Laboratory Saranac Lake New York Director Dear Dr. Gardner At a meeting yesterday attended by certain brake lining manufacturers Mr. Simpson and I were able to present to a fairly large group of interested corporations the proposal that one of your dusting chambers be engaged for further experi mentation with asbestos dust The proposal was very well received and it appears that not less than eight and perhaps ten or more corporations will participate in financing these further experiments along the lines discussed when we met with Dr. Lanza and Dr. McConnel a few days ago Accordingly you may consider this letter as an authorization to you to commence the contemplated experiments with asbestos dust for the purpose of determining more definit the causes and effects of asbestosis It is my understanding that among other questions which it is anticipated these exper ments will answer are the following 1 _ what concentration of dust is necessary to prouuce the fibrosis of the lungs which is designated as asbestosis 2 Whether exposure to asbestos dust will produce asbestosis without the existence of previous infection and whether the ray changes found in advanced human asbestosis can be reproduced in animals without infection 3 Whother the fibrosis produced by asbestos is of the progressive type that is will the fibrosis increase once it has started after exposure to the dust has ceased 30:7.3 30:73 30:73 > -2- saaera iat PLAINTIFF'S ileaeie adps. EXHIBIT i Ed PUTER Sal at 4 whether the fibrosis resulting asbestos dust is occasioned by tent of the asbestos or by its from exposure to the silicon con- fibrous structure 5 _ Whether the presence of asbestos diagnostic significance bodies has any will will that It is also our understanding that these experiments require approximately three years which will mean that they not be concluded until about the end of the year 1939 and they will cost 5,000 annually or a total of 15,000 It is our further understanding that the results obtained will be considered the property of those who are advanc- ing and the required funds in what manner they who will shall be determine whether to what ande public In the event extent it is deemed desirable that the results be made public the manuscript of your tion study will be submitted to us for approval prior to publica- I shall appreciate your advising me if the foregoing accurately expresses the proposition you had in mind Also let me know the manner in which you would like to have the funds ad- vanced to you Would you for example desire to have 1250 paid quarterly in advance or just what arrangement would suit you best Any method you suggest will be satisfactory Since the experiments are being underwritten by a relatively large group it has been suggested that as a matter of convenience any communications regarding the work be addressed to me and I will where necessary communicate the contents thereof to Mr. Simpson and the other parties You will be provided with funds by either Manville Corporation or Manhattan Incorporated and we or they will secure from the other parties their pre rata contribution I will advise you later of the names of the other con- tributing parties , I shall appreciate your informing no at possible moment whether the arrangement as outlined with your approval.. the earliest herein meets YB Sincerely yours You Brown You diver Brown diver Vandiver Brown General Attorney 004730 004730 004730