Document 2yBb1eB0genzLN4OaqmQv5p7

104 G. Berry, J. C. Gilson> S. Holmes, H. C. Lewinsohn, S'. A. Roach the non-smokers were on average younger than the Asbest smokers, aged 55 years compared with 58 years for those first employed before 1951, and 47 years dust 1< sures i compared with 52 years for those first employed after If tl 1950. The data are shown in age groups in Table 7. had a: After taking account of age, there were significantly to a 1< fewer signs in non-smokers and light smokers than in exposi heavier, and ex-smokers, for men first exposed after the m 1950: for crepitations, p < 0 01; for possible and posur< certified asbestosis, p < 01 and for small opacities by usi p < 0 05. first r< relatic Dose-response relationships RELA' Cumulative exposure (tibre-years/cm3) Fig. 3 The relationship between indices of lung function and cumulative exposure to asbestos, for men first employed after 1950. The dose-response relationships considered in this section are those between the prevalence or incidence of one of the three signs (crepitations, possible, or certified asbestosis) and a measure of dust exposure. The mathematical forms of dose-response relation ships and a discussion of methods for combiniftg the dust The s dust This (Britis equal takinf Table 6 The association between smoking and signs ofasbestosis Thed of du: 1 Employment group and smoking habit Mean cumulative exposure Numbers of men Total Crepitations Possible asbestosis Certified asbestosis Small radiological The tional assurr W-yrlcm') opacities* which First employed before 1951 i I Never smoked 1-4 cigarettes/day I 5-14 cigarettes/day D l 15+ cigarettes/day t Ex-smokers 197 22 4 3 2 109 7 3 3 1 188 62 22 IS 7 197 62 20 18 9 192 28 7 6 S 4 2 18 22 13 appro transf transf signs asbesi I First employed after 1950 Never smoked 1-4 cigarettes/day 5-14 cigarettes/day 15+ clgarcttes/day Ex-smokers 79 42 91 13 89 48 84 68 81 24 0 0 11 11 4 00 00 65 43 32 2 0 11 11 4 In of th> dose 51 ar respo Profusion 1/0 or more. Table 7 The association between smoking, age and signs ofasbestosis Employment group and smoking habit Age group Numbers of men Total Crepitations Possible asbestosis Certified asbestosis Small radiological opacities* of 1? limits the 1 f-yr/c illusti other stand Thi First employed before 1951 Never smoked and 1-4 cigarettes per day r-54 \ 55 + 11 18 0 7 0 6 i 2 0 6 Other smokers and ex-smokers f-54 \ 55 + 37 115 7 42 5 34 2 19 6 47 First employed after 1950 f-44 Never smoked and 1-4 cigarettes per day- 45-54 26 17 0 0 0 0 0 0 1 0 1 55 + 12 0 0 0 1 f-44 32 0 0 0 1 Other smokers and ex-smokers ( 45-54 51 8 5 4 10 [ 55 + 57 18 8 6 15 dose-: 1966 know know dusty effect cumu abou to bf ealeu crepii previ-