Document 2kedb2RZNo7nO9O3v5rgBw5N
November 20, 1936
LeKoy U. Gardner, II. D,, Director, The Saranac Laboratory, ' 8aranac Laice, New York,
Door Dr. Gardner*
At a meeting yesterday attended by certain 'Irana
lining manufacturers, Mr. Simpson and I were able to present
to a fairly large group of interested corporations the proposal
that one of your dusting chambers be engaged far further experl--,,
mentation with asbestos dust.
'
The proposal was very well received and it appears that not less than eight, and perhaps ten or more, corporations
.11 participate in financing these further experiments along die lines discussed when we met with Dr. Lanza and Dr. McConnell a few days ago.
Accordingly, you may consider tliis letter as an authorization to you to cormoance the contemplated experiments with asbestos dust for the purpose of determining aore definitely the causes and effects of asbestosls. It is my understanding that, among other questions which it is anticipated theso experi ments will answer, are the following*
(1) v"hat concentration of duat is necessary to .;rouuce the fibrosis of the lungs which is designated as
. asbestosls.
(2) Whether exposure to asbestos dust will produce asbestosls without the oxistence of previous infection and whethor the X-rny changes found in advanced huaaa asbestosls can be reproduced in animals without infection.
(3) Whether the fibrosis produced by asbestos is of the progressive typo, that is, will the fibrosis increase (onco It has started) after exposure to the duat has censod.