Document 2jdJv93NKeOeyrZoYG5MrBvKL

Octoiler 4, 19^7 / Tt/' .. // Dr. Goldman The Electric Storage Battery Company, Allegheny Avenue and 19th Street, Philadelphia 52 Pennsylvania. Dear Dr. Goldman: ; I am forwarding to you herewith duplicate signed copies of our reports_Qf the a n a ^ t ^ a l results on the urine and "blood of 1 also enclose a bill to cover the ^ o ^ ^ o ^ c a r r y i n ^ ^ u ^ b hese analyses. As I have indicated in the report, the results on are in agreement and are clearly indicative of his having had recent hazardous exposure to lead compounds. The information given concerning this patient is not ' such that we are justified in making any assumption as to the diag nosis . However, the results are compatible with a diagnosis of lead poisoning, if such a diagnosis is justified on other grounds. In the case of the lead concentration in the urine is high and is indicative of recent lead absorption. However, the lead concentration in the blood is just at the upper edge of normal values, thereby suggesting that this man has not had recent dangerous lead exposure. The sample of urine had a high specific gravity, and is therefore a somewhat concentrated sample. This may account for the discrepancy. I should be inclined to doubt if any of the present symptoms were due to lead absorption but would feel that these results should be checked by further analyses. It is possible that the sample of urine may have been slightly contaminated in its collection, in which case a further samples of both blood and urine would tend to clarify the significance of the lead exposure. .\ 1. . ,i In the above case as well as in future cases it would be well for us to have all of the available clinical information, since otherwise it is impossible for us to give an adequate interpretation of the analytical results. . Very truly yours, EAK ef Enc. Bobert A. Kehoe, M. D. Material: Submitted Required: (#1$03) Material and Blood 9-25-14.7 by Dr. Goldman, Electric Storage Battery Company, ...... Lead. Analyses Urine Analysis Number = l4.7A-6i4.36 Volume = 100 ml. Sp, Gr. = 1.020 Mg. Pb/Liter = O.2I4. Blood Analysis Number = lj.7A-6lj.37 Spec trographic Dithizone Grams 12.8 15.0 Mg, Pb/lOO g. 0 ,0 5 . O .065 The lead concentration in the blood is at the upper limit of normal values thereby indicating that this man's recent lead exposure has been of a low order of magnitude. The concentration of lead in the urine is relatively high. This may have resulted from the collection of a concentrated sample of urine, or it may have resulted from con- lamination in the process of collection. It might be the result of a very recent exposure of greater severity than that ordinarily present. The analyses should be repeated on additional samples to Sample Collected: 9"19"47 clarify these questions. Sample Received: 9**25-ii-7 Sample Reported: 9"30"47 Robert A . Kehoe, M . D . Kama: . Material* Suhralfcfced* (#490$) Material and Blood 9-25Ij7 by Dr* Goldman* Electric Storage. Battery Co-rp&ny, Philadelphia*. Pennsylvania Urine -' Analysis Humber- = ij.7A-*6!i3^ Volume = 100 si* Sp* dr* ; . 1.020 Mg* P'o/Lifcsr m 0 2I4. Hood Analysis'Humber I.i7&-6li3? Spec terojgraphic iiras? 12 #13 . i &* 0.05 0*065 The lead concentration in the blood is. at the upper limit of normal , thereby indicating that this man*s recent lead exposure has been of a lev order of magnitude. The concentration of lead in the urine is relatively high. This may have resulted from the collection of a concentrated sample of urine* or it may have resulted from con tamination in the process of collection. It might be the result of "a very recent exposure of greater severity than that ordinarily present "clar?ll,? t?hes.e rq.uTelstt?iLonl-. Semple Collected. 9-19-47 sSaammpjllee KSeMp*olrTt.eah.i 99--5050--4477 -' t A . Xehoe, Tu y!r <i1t>3 I&lMA- 7 7 JA ,3 ^ ^ G u l m 4"3pL J s 5) oldman, Electric Storage , Philadelphia, Pennsylvania = b-7k-6h3k = 72 ml. = 1.022 = O .32 Plooo Analysis Kumber Grams Mg. pb/100 g. If.7A-6if.35 Speatrographic 1C-.0.12 Dlfehlzone I9.I ' O.II5 the lead concentrations in both urine and blood are veil above normal limits and are indicative of recent hazardous exposureto lead compounds. Robert A. Kehoe, M.. D Samples Collected: 9"3-9"^7 Samples Received: 9"25-if7 Samples Reported: 9"3^-li-7 Name: Material: Submitted: ' Required: t H H H H H l (#lf925) Urine a.nd Blood 9"25-ij-7 by Dr. Goldman, Electric Storage Battery Company, Philadelphia, Pennsylvania Lead Analyses Urine Analysis Number = l4.7A-6 l4.3i.;. Volume = 72 ml.. Sp. Gr. = 1.022 Mg. Pb/liter = 0 .3 2 Blood . Analysis Number = Ii.7A-6l4.35 Spectro,graphic Grams ic. 3 Mg. Pb/100. g. 0 .12 Dithizone 1Q,1 O.II5 the lead concentrations in both urine and blood are well above normal limits and are indicative of recent hazardous exposure to lead . compounds. Robert A . Kehoe, M. D. Samples Collected: 9"19"V t Samples Received; 9-25*-i|7 Samples Reported: 9"'5"h-7 N 6882.04 amei ' ' arlalt -. Urina nd Blood Subltedt , -9~2$~h7 by ir# Ooldaum, lieatrio storage ; / ;. .- ' .- . B&fctery Company*. Philadelphia Pennsylvania .c\ .. '`- ' . 1 .' ,equirel. .... - Lead nalyae# . \ . . ' - ;?. ' '.' " . .. ' > : jv .' -. . . ` .... Urina .. '.- . * ' ' .< ' '' 5 - ' . ` ' ` : ' ' '' Analysis .omfeer m 'lt f * k3 k ' ' Volm m * ?2 al*. . .. . sp, *v i*oaa . Mg* Pb/&n'er * 0 3S ' . . ' " ' ' . _. .' B lood ' ' Amlysie Strsbor \ ' f $ * & k 3 5 , . : .' , Spcotregragfoie Dlthisone . cir&ssa-:" '.- 10* 3 ' . .19 * 1 % . m / p Q g. 0 ,12 . ' 0.115 itie lead concentrations ln both urine and blood are veil above normal limits and are Indicative of recent hazardous exposure to lead co&potoeds ' ' . . ' ' ' . : . ., " ; . . l^irTXTleHorWrST Samples Collected! 9 * %S~ h7 Samples Kecoivedt 9*25*4T gamploe. Reported t ^ m* -i 1it, -iriilt;linio ' - . ` '.- I : - - ` V' - i;=- or Lead T r * * , -, Robert A . Kehoe, M . D- College of Medicine Eden A/enue Cincinnati 19, Ohio October 4, ihe Electric Storage Battery Co., Allegheny Avenue and 19th St., Philadelphia J2, Pa. Attention: Dr. Goldman Analysis of Blood and Urine for Lead ' : 0004180