Document 2j64pG2ppGx04mYprVk1e2weR

Monsanto *c- t :; Linda L. Lewis November 21, 1980 Contribution to "Laboratory Safety" Handbook TO W. G. Juhl cc J. C. Bolding P. S, Glaspie R. K. McLeod A. M. Patterson I have been requested to help in the writing of a new text on laboratory safety (see attachment). Although I would consider this a personal project and not a job-related project, I need the approval of Monsanto to undertake it. I would also like to use Monsanto's technical library for references. I would prefer the situation of having open correspondence with the editor, and having the final draft circulated at Monsanto for approval. Please let me know if this proposal meets with your approval. Attachments Linda L. Lewis SC 16634 LAM023903 NDRMAN V. STEERE & ASSOCIATES, INC 140 MELBOURNE AVE. B. E., MINNEAPOLIS, MINN. ES414 PHONE (612) 378-3711 November 14, 1?80 Linda L- LEWIS,. Senior Chemist Monsanto Chemical Intermediates Company PO 5ox 1311 Texas City,TX 77590 Dear Ms. Lewis: Van Nostrand Reinhold Company has asked me to be the editor of a new text on laboratory safety, and we are beginning work on a book to be titled "Laboratory Safety and Health Our goal is to provide fundamental information on laboratory hazards and preventive measures for use by those teaching science.courses in high schools and colleges. You have been recommended as a person with experience and interest in laboratory safety and health, and one who could make a significant contribution by sharing your knowledge and insights. We understand that your company is also interested in chemical safety education for citizens and future employees. We would like to ha l your assistance with this project. "Laboratory Safety and Health" will be an updating and revision of "Guide for Safety in the Chemical Laboratory" prepared by the Manufacturing Chemists Association and published by Van Nostrand Reinhold in 1954 and revised in 1972. The Manufacturing Chemists Association, now the Chemical Manufacturers Association, has relinquished their rights to the Van Nostrand Reinhold publication and has withdrawn all of their other safety publications including the Laboratory Waste Disposal Manual. In order to meet the need for an available reference for disposal of laboratory waste, for the revised book we plan to compile new information on disposal of small quantities of common laboratory chemicals. We are looking for sources of assistance on this part of the project, and your recommendations are invited. Enclosed for your review and comment is a copy of the outline for the book and the type of information we are seeking for the Tables of Chemical Hazard Information. We would like to have your help on preparation of chapters on developing safety and health measures (14), emergency procedures (15), labeling needs (21), lock-out and tag-out procedures (23), hazardous chemical reactions (24), hazards in scale-up from research (25), evaluating hazards of unstable substances (26), evaluation of new processes and new products (27), and the tables of chemical hazard information (32) Although there is no provision for reimbursement of authors or contributors, we will acknowledge the individuals and companies who provide information and will recognize your contribution with a copy of the final book. We hope that you will be able to accept our invitation to participate in this project. We look forward to working with you and to publication of an exciting and useful book. Sincerely, 16635 LABORATORY SAFETY A DEB ION, FIRE A CHEMICAL SAFETY -- CONSULTATION, TRAININQ, PUBLICATIONS LAM023904 OUTLINE FOR LABORATORY SAFETY AND HEALTH BOOK for VAN NOSTRAND REINHOLD-3rd Edition of MCA Guide to`Safety-in the Chem.Lab Draft November 5, 1980 ! The basic idea is to start with the most simple and common needs and proceed through the more complex and less frequently used topics The Tables of Chemical Hazard Information planned at the back of the book are intended to include waste disposal information that is distinctly different from that previously provided by the MCA, which they will no longer provide or permit to be reprinted. We intend to try to have the Tables made available as a separate publication. ! CHAPTER NUMBER CHAPTER TITLE 1. Responsibilities for Laboratory Safety and Health 2. Principles of Accident and Disease Causation 3. Human Factors in Accident Causation M. Environmental Factors in Accident Causation 5. Energy Factors in Accident Causation HAZARDS IN LABORATORY ACTIVITIES 6. " " Fire Hazards in Laboratories and Research Activities 7. Health Hazards of Chemicals 8. Instability and Reactivity Hazards of Chemicals 9. Physical Hazards in Laboratory Activities 10. Electrical Hazards in Laboratory Activities 11. Radiation Hazards in Laboratory Activities 12. Thermal Hazards in Laboratory Activities 13. Biological Hazards in Laboratory Activities % SC 16636 LAM023905 CONTROL MEASURES FOR LABORATORY HAZARDS in. Developing Safety and Health Measures for Laboratory Activities ! Include Safety Orientation here or early in this section.! ! Include need for Waste Disposal planning!! ! 15. Emergency Procedure Development, Preparation, and Practice 16. Fire Extinguisher Needs and Limitations 17. Techniques for Preventing Chemical and Biological Contamination 18 Protective Clothing for Minimizing Personal Contamination 19 Respiratory Protective Equipment Needs and Limitations 20 Laboratory Exhaust Ventilation Needs and Limitations 21 Labeling Needs and Systems 22 Laboratory Equipment Hazards and Precautions 23 Lock-Out and Tag-Out Procedures for Equipment Maintenance 24 Hazardous Chemical Reactions 25 Hazards in Scale-up from Small Quantities Used in Research 26 Evaluating Hazards of Unstable Substances 27 Evaluation of New Processes and New Products 28 Safe Handling of Compressed Gases and Cryogenic Fluids 29 Electrical Safety Inspection Measures 30 Special Storage Requirements for Chemicals and Flammables and Hazardous Wastes 31 Laboratory Design for Optimum Performance and Safety and Health 32 Tables of Chemical Hazard Information !We need to be sure we have covered all the requirements for identifying, treating, packaging, etc.etc. for hazardous wastes. If possible, the Tables will include methods for treating small "laboratory" quantities of the chemicals listed. ! 16637 LAM023906 TABLES OF CHEMICAL HAZARD INFORMATION Chemicals to be included: Chemicals listed in ACGIH TLV Chemicals listed in NFPA No. ^9 Chemicals listed in Handbook of Laboratory Safety Chemicals with AIHA Hygienic Guides published Priority Pollutants Chemicals commonly used in intro, laboratory courses *6638 Information to be included: Chemical Name and Formula Chemical Abstracts Registry Number . Cost of the chemical (eg. $ /100 mg of reagent grade ) '.This information could be helpful in waste decisions such as whether to save it, chuck it, or salvage it.! Fire Hazard information, including Flash Point, Flammable Limits, Ignition Temperature, Extinguish ing Agents, and whatever else pertains, such as largest size glass container permissible. Health Hazard information, including whether compound is Corrosive, Irritant, etc, the toxic dose reported (LD 50, animal, and route of admin.), basis for TLV, relative hazards from concentrated short-term exposure (/H.L.Smyth in HLS.), references if compound has been reported carcino genic or having other unusual effects, and whatever other information is available that is pertinent, brief, and important, such as symptoms of acute or chronic overexposure. One format we might consider is the one we used in the manuals for EPA. Another bit of information, if we could get it, would be the precautionary statements used on labels by the leading chemical companies. Packaging and Shipping Requirements / DOT Spill Control Recommendations Waste Recycling, Treatment, or Disposal Recommendations !I like the format I used in the Handbook of Laboratory Safety Tables of Chemical Hazard Information, but that format cannot be used. Should we consider including any of the other physical data listed there, such as Boiling Point/Melting Point, Vapor Pressure, Density or"*Specific Gravity, and Water Solubility?? ! !Note on November 9, 1980: Let's include the physical data. ! LAM023907