Document 2j648RV40gDxbYxQoJ5e3vRg6

:ateI'"al safety data sheet ,igma Chemical Co. '.0. Box 14508 3t__Louis, MO 63178 >h -i: 314-771-5765 Aldrich Chemical Co 1001 West St. Paul Milwaukee, WI 53233 Phone: 414-273-3850 Inc. Fluka Chemical Corp. 980 South Second St. Ronkonkoma, NY 11779 Phone: 516-467-3535 database Version May 01, 1996 3ECTION 1. --------- CHEMICAL IDENTIFICATION- --------- CATALOG #: 48541 NAME: TRICHLOROFLUOROMETHANE NEAT STANDARD FOR EPA METHODS 3ECTION 2. ----- COMPOSITION/INFORMATION ON INGREDIENTS ------ CAS #: 75-69-4 EC NO: 200-892-3 SYNONYMS ALGOFRENE TYPE 1 * ARCTON 9 * ELECTRO-CF 11 * ESKIMON 11 * F 11 * FC 11 * FLUOROCARBON NO. 11 * FLUOROTRICHLOROMETHANE (OSHA) * FLUOROTROJCHLOROMETAN (POLISH) * FREON 11 * FREON 11A * FREON 11B * FREON HE * FREON MF * FRIGEN 11 * GENETRON 11 * HALOCARBON 11 * ISCEON 131 * ISOTRON 11 * LEDON 11 * METHANE, FLUOROTRICHLORO- * MONOFLUOROTRICHLOROMETHANE * NCI-C04637 * REFRIGERANT 11 * TRICHLOROFLUOROMETHANE (ACGIH:OSHA) * TRICHLOROMONOFLUOROMETHANE * UCON FLUROCARBON 11 * UCON REFRIGERANT 11 * SECTION 3. ---------- HAZARDS IDENTIFICATION --------- T '.BEL PRECAUTIONARY STATEMENTS IRRITANT IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN. TARGET ORGAN(S): HEART LUNGS IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF WATER AND SEEK MEDICAL ADVICE. WEAR SUITABLE PROTECTIVE CLOTHING. DO NOT BREATHE VAPOR. SECTION 4. ---------- FIRST-AID MEASURES- ---------- IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. IN CASE OF CONTACT, IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS AMOUNTS OF WATER. IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN. IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS. CALL A PHYSICIAN. WASH CONTAMINATED CLOTHING BEFORE REUSE. SECTION 5. --------- FIRE FIGHTING MEASURES ---------- EXTINGUISHING MEDIA APPROPRIATE FOAM. USE WATER SPRAY OR FOG NOZZLE TO KEEP CYLINDER COOL. MOVE CYLINDER AWAY FROM FIRE IF THERE IS NO RISK. SPECIAL FIREFIGHTING PROCEDURES WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO '^PREVENT CONTACT WITH SKIN AND EYES. ,, {USUAL FIRE AND EXPLOSIONS HAZARDS EMITS TOXIC FUMES UNDER FIRE CONDITIONS. D0 a 061864 SECTION 6.------------------------------- ACCIDENTAL RELEASE MEASURES------------------------- CONFTDFNTTAl SHUT OFF ALL SOURCES OF IGNITION. EVALUATE AREA AND KEEP PERSONNEL UPWIND. WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY RUBBER GLOVES. COVER WITH DRY LIME OR SODA ASH, PICK UP, KEEP IN A CLOSED CONTAINER AND HOLD FOR WASTE DISPOSAL. VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE. ,ECTION 7. ---------- HANDLING AND STORAGE- ---------- PREFER TO SECTION 8. OITIONAL INFORMATION INCOMPATIBLE WITH: COPPER, BRONZE, SILVER, BERYLLIUM, ALKALI AND ALKALINE EARTH METALS. SECTION 8. ------ EXPOSURE CONTROLS/PERSONAL PROTECTION- ----- CHEMICAL SAFETY GOGGLES. COMPATIBLE CHEMICAL-RESISTANT GLOVES. NIOSH/MSHA-APPROVED RESPIRATOR. MECHANICAL EXHAUST REQUIRED. SAFETY SHOWER AND EYE BATH. AVOID BREATHING VAPOR. DO NOT GET IN EYES, ON SKIN, ON CLOTHING. AVOID CONTACT AND INHALATION. WASH THOROUGHLY AFTER HANDLING. IRRITANT. KEEP TIGHTLY CLOSED. SECTION 9. ------- PHYSICAL AND CHEMICAL PROPERTIES ------- APPEARANCE AND ODOR LIQUID. PHYSICAL PROPERTIES BOILING POINT: 23.7 C MELTING POINT: -111 C SECTION 10. --------- ------------------------- STABILITY AND REACTIVITY------------------- ---------------- STABILITY STABLE. INCOMPATIBILITIES STRONG OXIDIZING AGENTS REACTS WITH: ...SODIUM POTASSIUM MAGNESIUM ALUMINUM ZINC STORE AWAY FROM HEAT AND DIRECT SUNLIGHT. HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS TOXIC FUMES OF: CARBON MONOXIDE, CARBON DIOXIDE HYDROGEN CHLORIDE GAS PHOSGENE GAS HYDROGEN FLUORIDE HAZARDOUS POLYMERIZATION WILL NOT OCCUR. SECTION 11. --------- TOXICOLOGICAL INFORMATION -------- ACUTE EFFECTS MAY BE HARMFUL BY INHALATION, INGESTION, OR SKIN ABSORPTION. VAPOR OR MIST IS IRRITATING TO THE EYES, MUCOUS MEMBRANES AND UPPER RESPIRATORY TRACT. CAUSES SKIN IRRITATION. CAN CAUSE RAPID SUFFOCATION. PROLONGED OR REPEATED EXPOSURE TO SKIN CAUSES DEFATTING AND DERMATITIS. EXPOSURE CAN CAUSE: NAUSEA, DIZZINESS AND HEADACHE STOMACH PAINS, VOMITING, DIARRHEA. ~IiMAY CAUSE NERVOUS SYSTEM DISTURBANCES. 'WEAKNESS UNCONSCIOUSNESS TARGET ORGAN(S): HEART DO A 061865 CONFIDFN7TAI LIVER rjO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED. ADDITIONAL INFORMATION EXPOSURE TO HIGH CONCENTRATIONS OF VAPOR MAY CAUSE LIGHT-HEADEDNESS DISORIENTATION, NAUSEA, VOMITING, NARCOSIS, CARDIAC DYSRYTHMIAS, -^HYPOTENSION AND DEATH. THE CARDIAC DYSRYTHMIAS ARE POTENTIALLY LETHAL ..JECAUSE OF SENSITIZATION OF MYOCARDIUM TO ENDOGENOUS EPINEPHRINE. RTECS #: PB6125000 METHANE, TRICHLOROFLUORO- TOXICITY DATA IHL-RAT LC50:13 PPH/15M HUTODJ 1,239,82 IHL-MUS LC50:10 PPH/30M EJTXAZ 9,385,76 IPR-MUS LD50:1743 MG/KG TOIZAG 18,363,71 IHL-RBT LC50:25 PPH/30M EJTXAZ 9,385,76 IHL-GPG LC50:25 PPH/30M EJTXAZ 9,385,76 TARGET ORGAN DATA BEHAVIORAL (CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD) ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR COMPLETE INFORMATION. ECTION 12. --------- ECOLOGICAL INFORMATION ---------- DATA NOT YET AVAILABLE. ECTION 13. -------------- ------ ---------- DISPOSAL CONSIDERATIONS ------------------------------------ DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS. ECTION 14. ---------- TRANSPORT INFORMATION --------- CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION. ECTION 15. --------- REGULATORY INFORMATION ---------- EUROPEAN INFORMATION IRRITANT R 36/37/38 -..IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN. JS 26 IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF WATER AND SEEK MEDICAL ADVICE. S 36 WEAR SUITABLE PROTECTIVE CLOTHING. S 23 DO NOT BREATHE VAPOR. REVIEWS, STANDARDS, AND REGULATIONS OEL-MAK ACGIH TLV-CL 1000 PPM 85INA8 6,1619,91 EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,89 MSHA STANDARD-AIR:TWA 1000 PPM (5600 MG/M3) DTLVS* 3,118,71 OSHA PEL (GEN INDU):8H TWA 1000 PPM (5600 MG/M3) CFRGBR 29,1910.1000,94 OSHA PEL (CONSTRUC):8H TWA 1000 PPM (5600 MG/M3) CFRGBR 29,1926.55,94 OSHA PEL (SHIPYARD):8H TWA 1000 PPM (5600 MG/M3) CFRGBR 29,1915.1000,93 OSHA PEL (FED CONT):8H TWA 1000 PPM (5600 MG/M3) CFRGBR 41,50-204.50,94 OEL-AUSTRALIA:TWA 1000 PPM (5600 MG/M3) JAN93 OEL-BELGIUM:STEL 1000 PPM (5620 MG/M3) JAN93 OEL-DENMARK:TWA 1000 PPM (5600 MG/M3) JAN93 OEL-FINLAND:TWA 1000 PPM (5600 MG/M3);STEL 1250 PPM (7000 MG/M3) JAN93 f^OEL-FRANCE:TWA 1000 PPM (5600 MG/M3) JAN93 ^uEL-GERMANY: TWA 1000 PPM (5600 MG/M 3) JAN93 OEL-HUNGARY:STEL 40 MG/M3 JAN93 OEL-JAPAN:STEL 1000 PPM (5600 MG/M3) JAN93 OEL-THE NETHERLANDS: TWA 1000 PPM (5600 MG/M3) JAN93 170 A 061866 OEL-THE PHILIPPINES:TWA 1000 PPM (5600 MG/M3} JAN93 CONFTDFNTTAL OEL-POLAND:TWA 500 MG/M3 JAN93 C2L-RUSSIA:STEL 1000 PPM (1000 MG/M3) JAN93 OEL-SWEDEN:TWA 500 PPM (3000 MG/M3);STEL 750 PPM (4500 MG/M3) JAN93 OEL-SWITZERLAND:TWA 1000 PPM (5600 MG/M3) JAN93 OEL-TURKEY:TWA 1000 PPM (5600 H3/M3) JAN93 OEL-UNITED KINGDOM:TWA 1000 PPM (5600 MG/M3);STEL 1250 PPM JAN93 _OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA CHECK ACGIH TLV "DEL IN'NEW ZEALAND, SINGAPORE, VIETNAM CHECK ACGIH TLV NIOSH REL TO FLUOROTRICHLOROMETHANE-AIR:CL 1000 PPM NIOSH* DHHS #92-100,92 NOHS 1974: HZD 33565; NIS 304; TNF 68187; NOS 173; TNE 785337 NOES 1983: HZD 33565; NIS 142; TNF 15107; NOS 119; TNE 267742; TFE 95886 EPA TSCA SECTION 8(B) CHEMICAL INVENTORY ON EPA IRIS DATABASE EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, OCTOBER 1995 NIOSH ANALYTICAL METHOD, 1994: FLUOROTRICHLOROMETHANE, 1006 NIOSH ANALYTICAL METHOD, 1994: TRICHLOROFLUOROMETHANE, 1006 NCI CARCINOGENESIS BIOASSAY (GAVAGE);NO EVIDENCE:MOUSE NCITR* NCI-TR-106,78 NCI CARCINOGENESIS BIOASSAY (GAVAGE);INADEQUATE STUDIES:RAT NCITR* NCI-TR-106,78 U.S. INFORMATION THIS PRODUCT IS SUBJECT TO SARA SECTION 313 REPORTING REQUIREMENTS. 3ECTION 16. ---------- OTHER INFORMATION- ----------- THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH, FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE. COPYRIGHT 1996 SIGMA CHEMICAL CO., ALDRICH CHEMICAL CO., INC., FLUKA CHEMIE AG LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY ) 00 A 062867 CONFIDFNTIAL