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CENTRAL ANALYTICAL LABORATORY ARG-OHUE
Report No. 6910oenrenen
Datay e16:.29.78..
qubject: -143 Analysis of IRC 137-090 Samples Name ..TQxicelogy.
Proj. No..2172339004
Requestor:--- lB. LORSRequest No. ..AG86LE
Dept. Dated .... 4/A/ 8 ceeenn
Reports serum
and
Livers
from
TRC
study
137-030
(50
day
subacuce chetuy
sis of PC-143
monkey toxicity with PC-143) vere Jeceived for analy
sonke/ pose survival SSeerrunm Llivmer touitvaerlg
236m
0
yes
73868
0
yes
seam 73664
3 me/kesasy .
yes yes
73807 7385
. .
yes yor
- 0.05
3
\ 0.07
5
53 w
3-
250_
os 50
,-
350s
7363M
74584
10 mg/kg/day
.
yes
yes
45
$
7n
-
600
-
7328F
.
yes
79
-
-
7383F
"
yes
7
10
750
236m Tass
30 meskg/dsy .
mo yes
EE us 0
5000 1000
23820 7387
. .
no ro
EoE us
2500 9000
Jusew 100 me/ka/day no
-0
6000
7381F
"
no
Q4 = mate, P= female
-
325
20000
C01764
'
ALR. #0919
- 2-
May 16, 1978
dote nat both male and female monkeys accumulate FC-143 to about the
acid. He used a female rat and found rapid excretion of the compound.
would the results agree with the IRDC (137-089) study?
/3z R.A. Prokop
236-38
Qe Rel Le
61765