Document 2RpLDOmeMDqXB8QvOkaoJrr5g

BIOLOGICAL EFFECTS OF ASBESTOS LYON, October 2-5, 1972 Paper 20 Criteria for Environmental Data and bases of Threshold Limit Values Environmental Data in Industry. S. Holmes. UCC 009528 20-2 INTP.QDTJUTION A paper on the theory and application of hygiene standards is to he presen ted at this conference hy Earry (Paper 22). . In this paper he outlines the establishment of the hygiene standard for chrysotile by the British Occupational Hygiene Society in 1968, being careful to point out that the data was based on experience with a group of men haring a minimum of 10 years exposure working in a particular asbestos textile mill at a particular time (June, 1966). No account was taken of men who had worked for the minimum period but had left the industry before that data. Thus the information, although "the beet available at the time, was, to say ' the least scanty for the purpose and some of us who were associated ' with it have become inereesingly concerned with the authority with which * it hae become invested in the international field. The time hae there fore probably arrived for an up-to-date re-appraisal of the original date and the study of new data which has since become available elsewhere. Unfortunately, any retrospective study will be unlikely to meet all the conditloam asssssscy to csiotietea reliable standard and therefore a proapaettva etady must be usdaetakes, properly deeijpad and directed towards the callaetion of the riit information. , TTff? HEBXCAL ASPECT The B.O.H.S* standard for chrysotile was established at a dose level, designed to limit to 1^ the risk of contracting the first signs of asbestosie. The criterion used by Knox was the presence of persistent baeal rales. He also looked at X-ray changes, using the techniques available at the time and noted that while all subjects exhibiting X-ray changes also had persistent rales, some subjects had rales without X-ray changes. Fe therefore concluded that rales gave the earliest demonstrable sign.. Since that time, X-ray techniques have improved UCC 009529 20 - k variations in most processes, although the recently introduced U.S. ' standard calls for an 8 hour average. Samples should be taken at reasonable intervals to ensure that possible long-term variations in dust levels due to changes in asbestos fibre quality or variations in performance of dust control equipment are adequately covered. The proposal under the D. of E. Medical Surveillance Scheme to base the exposure of the worker on a single dust sample taken at two-year intervals can hardly be regarded as satisfactory, but the industry itself may be able to supplement this from its own measurements. AREAS TO BE COVERED ' In establishing standards related to the asbeatosis risk, it is advisable to choose situations, such as factory operations, where dust concentrations do not fluctuate widely. It is unwise to use for this purpose processes experiencing high: packs of cansaetzation^ because too little ia still known about- the effects of such peaks, albeit for short periods of time, on th* normal lung dasranee mechanisms* Tb aassea pasadbis difference* in the effects of the different type* of asbestos, the areas of study should be chosen where idle exposure is to one type only - mixed exposures should be avoided. Even in one type of a8beetos, there may be variations between deposits from different mining locations which could have a bearing on their biological effects. It is therefore advisable to keep records wherever possible of the origin of the raw material. POEM OF THE STANDARD In establishing the B.O.H.5. standard for chrysotile, it was assumed that asbeatosis was a dose-related disease and therefore the adoption of a standard in the form of a limitation on total integrated exposure ^ -- -- -- * -- 44---- * mo^ UA B B noVI a --. ---- rw 01 4-5 rtn Va+Hi a rr Kao UCC 009530 21 May 1974 Dr. Raymond T. Moore NIOSH . Department of Health, Education, Parilawn Building 5600 Fishers* Lane Rockville, Maryland 20352 and Welfare Dear Dr. Moore: With regard to the June 5 hearing on the proposed health standard for occupational exposure to asbestos in coal mine working areas, please be advised that I and one other representative of the Association, to be named, plan to attend. Sincerely, Executive Director RHM/cg ec:\/williaHi C. Thurber UCC 009531 OFFICE OF THE DIRECTOR UNITED STATES DEPARTMENT OF THE INTERIOR BUREAU OF MINES WASHINGTON, D.C. 202 January 10, 1973 Hr. Matthew M. Swetonlc Executive Secretary Asbestos Information Association 22 East 40th Street New York, New York 10015 Dear Mr. Swatonic:. This acknowledges your letter dated December 20, 1972, relative to the Notice of Proposed Rule Making, 30 CFR 71, published in the Federal Register on November 7, 1972. We will give your comments careful consideration before publishing the mandatory standards in the Federal . Register. Sincerely yours, E. F. Osbom Director UCC 009532 I I I Asbestos Information Association/North America 22 East 40th Street New York, N. Y. 10016 212-689-3378 December 21, 1972 Gentlemen: Attached for your information is a copy of the AIA/NA submission to the Department of the Interior on the proposed two fiber asbestos standard for surface coal mine operations. Because . the documents mentioned in the submission have been distributed previously, they are not included in this mailing. For further background information on this subject, see my. distributed reports of November 13 and December 6. - The Johns-Manville Corporation also submitted comments to Interior objecting to the proposed two fiber standard. & copy of the J-M submission will be distributed in the near future. If any other companies in the industry submitted comments, we would appreciate receiving a copy for our files. Sincerely, Matthew M. Swetonic Enclosure UCC 009533 20-6 only fee hoped that the continuing accumulation of data relating the morbidity of asbestos workers to exposure to the different types of asbestos may throw further light on the problem. THE PRESENT POSITION It is now six years 3ince the data on which the B.C.E.S. standard for -chrysotile was based was presented and, in collaboration with Dr. Levinsohn, arrangements are feeing made to have the information from the same factory brought up-to-date. Unfortunately, although, new subjects will have come within the orbit of the study, others in the original study will, have left the industry in the meantime and the results might , still be biassed. Under the D. of E. Medical Surveillance Scheme, however, provision is made for a follow up of workers after they leave the industry and provided- adequate dust monitoring' arrangements are made, the type of data required* for the establishment of valid hygiene standards will become eweiXaMUr in: due-course* . ' UCC 009534