Document 2Revvr3D937RJOawRXnM04Q67

ASSOCIATED ETHYL COMPANY LIMITED J-teyislen d O ffice: THE ADELPHI, LONDON, W c 2 . JeUressall communicationsuntilfarthernoticeto- ARTILLERY HOUSE, ARTILLERY ROW, LONDON, S.W 1 'Tbrerfors JetrjJione: a bbey 397A-7 ' " ` S * O . L E C H * J O N f9 * GASS H i W ILTON ( u .S .a ) ;.S AUG, K E S S L E R (HeTNCRLANOS} fG.C.M O RRlS ft-W. S E L L E R S O -A .- S H E P A R D (u-S. Ai A.u. SIN G LETO N E -E .S O U S R r X R . A . S E V A N fJH nnfU p/U jj Dclcgrams: et nyl por t ,sowest , London OURREF. S p / 5 / 3 1 0 , YOUR RET. 28th February, 1947. Dr. R.A.Kehoe, The K e tte rin g L ab o rato ry , College of Medicine, U niversity of C incinnati, OHIO. Dear Dr. Kehoe, A ttached h e re to i s a l e t t e r signed by Dr. C a sse lls, but which i s , in f a c t, a jo in t o n in ^ n w ith Dr.Davison concerning the case ofl one of th e men, who,you w ill r e c a l l , C o n tra cted lead in to x ic a tio n a t Falmouth in 1945. Me would be g r a t e f u l i f you w ould l e t us h av e y o u r opinion regarding the point raised in the la s t p a ra g ra p h , namely th e permanence o f m ental symptoms f o l l o w i n g TEL p o i s o n i n g . . F r r y o u r i n f o r m a t i o n we a r e a l s o e n c l o s i n g copies of two o th e r l e t t e r s reg ard in g Drury. These w ill give you a b e tte r p ic tu re o f h is h is to r y and w i l l u n d o u b te d ly be o f some v a lu e i n y o u r r e c o r d s . Yours sin c e re ly , MAP/arn, 0021508 .'V f, yV >, fei u 7*?` r Y V BRITISH ETHYL. CORPORATION LTD. J . G. L e a f , E sq,., JA s s o c i a t e d E t h y l Co. L t d . , 'A r t i l l e r y House, A r t i l l e r y Row, LONDON, 8 . U . I . ITORTKUICH, CHESHIRE. 2 6th F e b ru ary , 1947 Dear Hr. Leaf, W ith r e f e r e n c e t o y o u r l e t t e r o f 6 t h F e b r u a r y a b o u t t h i s man, t h e r e s u l t o f t h e a n a l y s i s w hich was c a r r i e d o u t on a 'sample o f h i s u rin e by Hr. S.R. Smith of the C curtauld I n s t i t u t e , i s as follow s: - Urine Sample received 2 7 .1 .4 7 . from Falmouth . Vol lig Lead in U ml. Sample l i t r e G gm. ' Hgn. p b / a s h 'gra. ash S.G . * 434 .0120 .028 .037 6.20 1.95 1018 c le a r . (E.R. SiHTH). This r e s u l t shows t h a t j J U n o w has a no-rial amount of le ad in m : u rin e and is no longer s u ffe rin g from a c tiv e lead in to x ic a tio n . His oddity of behaviour, bad dreams, sle e p le ssn e ss, depression and c o n f u s io n , w hich a r e m entioned i n D r. Aildrewfe' l e t t e r o f ,15th November, 1946, a copy of which was s e n t t o ?rr. Bevan, must t h e r e f o r e be -. - (a) the re su lt of previous lead in to xication (b) due to an in h eren t nervous i n s ta b ili ty (c) due to an i n h e r e n t n erv o u s i n s t a b i l i t y a g g ra v a te d by lead intoxication (d) t h e r e s u l t o f some o t h e r t o x i c f a c t o r w hich i s s t i l l operating. RE 0.021509 (C ontd.}- - AAh*- . *. * * , v ' ]Si 24606.01 J.G . L e a f E s q ., The A s s o c ia te d E t h y l Co. Ltd. 2 6 th F ebruary, 194? In co n sid erin g these one must take in to account the follow ing fa c ts :- With regard to (a) i t i s extrem ely ra re indeed, i f not a c tu a lly unknown, f o r th e m ental symptoms and sig n s of t e t r a e th y l lead i n t o x i c a t i o n t o b e p e rm a n e n t. When r e c o v e r y o c c u r s - a s , a c c o r d i n g to Dr. Coleman' s l e t t e r o f 8th March, 1946 to P ro fe s so r Dodds, i t d id do - one does n o t lo o k f o r a r e t u r n o f symptoms. I f th e y do return i t is unlikely th a t lead in to x icatio n is the cause. With reg ard to (b) th e re is evidence in th e h is to ry which I to o k f r o m j K ^ w h e n I saw him t h a t he had i n f a c t some i n h e r e n t nervous in s ta b ility in th at his reactions to certain incidents in h is l i f e were somewhat abnormal. With regard to (c) i t i s re a so n a b le 1to acc ep t as p ro b a b le th a t lead in to x ic a tio n aggravated his nervous i n s t a b i l i t y and p re c ip ita te d th e m ental i l l n e s s on acc o u n t of w hich he was a d m itte d t o Bodmin Meata.l h o s p ita l. With regard to (d) th e re i s c e r ta in ly a p o s s i b ili ty th a t his c o n d i t i o n a s d e s c r i b e d on 1 5 th November, 1946, may be due to m e d ic a tio n which he has re c e iv e d s in c e h i s d is c h a r g e from Bodmin M ental H ospital as Dr. Davison suggests, and t h i s p o s s i b ili ty should be investigated. -' I n th e meantime f o r th e in f o r m a tio n o f o u r s e lv e s i t would be h e lp fu l to have an ex p ressio n of Dr. Kehoe' s views on th e question as t o w h eth er he has known o f any ca se o f t e t r a e t h y l le a d p o is o n in g (or of lead encephalopathy from inorganic lead) where the mental symptoms have been p e rm a n e n t. I f t h e c a s e sh o u ld come to c o u r t and Dr. Davison or I be obliged to appear, i t would s u sta in our c o n f i d e n c e . a p p r e c i a b l y t o know t h a t no c a s e s showing perm anent m e n ta l derangem ent a r e known t o Kehoe. '\ Yours sin c e re ly , DAVID A.K. CASSELLS.