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Sherman 14JAN98.doc From Steve Phillips To: Denny Mountz 14JAN98 Subject Meeting with W ndy Sherman on 14JAN98 page 1 of 2 1 met with Wendy Sherman of CMA on 14JAN98 to get an overview of the activities that she monitored that OxyChem participated in. These notes are reflective of that meeting. S. Wendy Sherman - Vinvl Chloride 2 Committees Health Committee (was JBK) Transportation (George Marshall) OxyChem's costs of 1998 = $25,785 (not paid yet) Budget Molecular Research - Swenberg Risk Assessment (EPA/IRIS) Outside Legal Contingency/General TOTAL $75,000 $20,000 $15,000 $40,000 $150,000 Administrative Costs $120,000* *paid from carried over money Shares Dow Chemical Occidental Chemical Formosa GEON Condea Vista Borden Georgia Gulf PPG TOTAL 25% 17% 15% 13% 10% 7% 7% 6% 100% 004598.001 From Stev Phillips To: Denny Mountz 14JAN98 Subject Meeting with Wendy Sherman on 14JAN98 page 2 of 2 ATTACHMENTS 1) Commitment form $25785 2) Vinyl Chloride health Committee 1998 Research Budget Program dated 4DEC97 3) Molecular Dosimetry of vinyl Chloride James A. Swenberg, DVM, Ph.D. Research report and Budget Request 28JUL97 4) Vinyl Chloride Health Committee members 5) Vinyl Chloride Transportation Committee 6) Letter of 12JAN97 to VCHC Members re: meeting 19FEB98 in North Carolina 7) Vinyl Chloride Health Committee (VCHC) Activities 8) Vinyl Chloride Panel History and Accomplishments 9) Vinyl Chloride Health Committee 1997-1998 Program Budget 004598.002 <r LJtn d y CHEMICAL MANUFACTURERS ASSOCIATION Vinyl Chloride Health Committee ( Commitment Form"^, 0 My company. Occidental Chemical Company, commits S 25,785 to the Vinyl Chloride Health Committee 1998 Research Budget Program as outlined in the attached December 4,1997 correspondence. Please invoice my company for the 1998 budget as indicated below. The Vinyl Chloride Health Committee is conducted under the policies and procedures outlined in the CHEMSTAR Panel Guidelines and briefly noted on the reverse of this form. Please send me an invoice for $ 25,785 in December 1997 __in January 1998. CMA has estimated that!3% o theJunel,1997 - May 31,1998 fiscal year "dues and similar income'1' isallocableto lobbying^and political expenditures to which Section 162 (e)(1) of the Internal Revenue Code-of1986,as amended, applies. Consequently, this portion ofyoor commitment iffnot deductible as an ardinaiy-aiid necessary business expense for federal income tax purposes. Purthei, contributions to CMA are not tax deductible as dumtable contributions. i Panel Representative Management Contact (Optional) Name (Signed) Name (Signed) Name (Typed) Name (Typed) Title Title Company Company Address Address Telephone Telephone Fax Fax Please return signedform to Wendy K. Sherman, Manager, Vinyl Chloride Health Committee, 1300 Wilson Boulevard, Arlington, VA 22209. 004598.003 Vinyl Chloride Health Committee 1998 Research Budget Program December 4,1997 Activity Molecular Research-J. Swenberg Risk Assessment (EPA/IRIS) Outside Legal Contingency/ General Approved Budget* 75.000 20,000' 15.000 40,000 150,000 Company Borden Chemical Dow Chemical Formosa Flashes GEON Georgia Gulf Occidental Chem PPG Industries CONDEA Vista Chemical TOTAL Capacity (millions of lbS%> of Total Capacity 1,030 3,600 2,160 7.08 24.76 14.85 1,900 1,026 2,500 13.07 7.06 17.19 840 1,485 5-78 1021 Total Commitment Required 10,620 37,140 22275 19,605 10390 25,785 8,670 15315 14341 100.00 150,000 004598.004 The Carryover Surplus and interest generated will cover the estimated administrative costs of $120,000 for 1998. Molecular Dosimetry of Vinyl Chloride James A. Swenberg, D.V.M., Ph.D. Research Report and Budget Request July 28,1997 004598.005 Research Report Year 1 (1996-1997 Budget) The laboratory portion ofthis project began this spring by sending teams of3-4 of our laboratory personnel to New Jersey to collect tissues and liver cell types from rats that were exposed to 0.10.100. or 1100 ppm vinyl chloride (VC) for 1-20 days. Procedures were rather difficult during the first set ofnecropsies, but went much better for subsequent procedures after we sent an additional person and shipped up our own centrifuge. We were able to harvest good yields ofcells and tissues for the experiment as a whole. It was unfortunate that the ["CJ-VC experiment was the first to come off. as this was the least smooth running ofall. Even so. adequate numbers ofcells were able to be harvested to meet our objectives. We are currently isolating DNA from the 4-wcek hcpatocytcs. as these are the most plentiful cells. A new immunoaffinity chromatograph-GC/MS method is replacing our previous low pressure strong cation cxchangc-GC/MS method for the analysis ofcthenoguauine. After this shakedown, we will begin working with the [CJ-VC liver cells. Parallel to this effort will be the analysis of urines for excretion ofethenoadenine using immunoaffinity chromatography and LC-MS. Likewise, we will begin examining the major DNA repair pathway for VC DNA adducts including methyl purine glycosylasc (MPG) and AP-cndonuciease (AP). Year 2 (1997-1998 Budget) During Year 2 wc will continue to work up the many samples collected in New Jersey'. Priority will be given to establishing exposure response relationships, identifying cell-specific differences in DNA repair, determining effects of exposure on endogenously formed DNA adducts, and doing initial studies related to incorporating these data into a PB/PK risk assessment model. Wc are also developing new methods for the lN,2-ethcnoguaninc adduct, which has never been characterized in vivo. Year 3 (1998-1999) We expect to complete this research during the third year. At this time, we will have analyzed all ofthe relevant tissues and cells for DNA adducts, will establish the role ofdefects in DNA repair and die effect of induction ofDNA repair on exogenous and endogenous DNA adducts, and incorporate these data into a biologically-based risk assessment model. 004598.006 3 Research Budget Mv understanding ofthe funding available for this project is that between S50.000-75.000 will be available per year for three years. The cost ofthis research project will greatly exceed this, with personnel costing --SI40.000 this year. However, since VC has been and continues to be one of the chemicals that we are investigating under our NIEHS Superfund Basic Research Program Project I can offset part ofthe cost, providing that the CMA agrees to share acknowledgement with NIEHS. Should we need additional ["CJ-VC exposures, they can be done at UNC, since the EOIC lias agreed to fund new research that includes funds to set up a small nose-onlv exposure system for similar studies on ethylene oxide. Thus, we can maximize our future research dollars to fund critical studies. We need to move forward as fast as possible, as the EPA has ?'ready developed a new risk assessment on VC that suggests increased risk compared to their previous estimates. The new' assessment incorporates metabolism data, but not information on DNA adducts or DNA repair. Finally, we incurred major expenses during die four trips to New Jersey that were not included in Year l's budget. These are listed under sample collection in the budget 1997-1998 Budget request Sample collection Travel expenses Shipping Supplies Research budget Personnel Supplies LC-MS/MS time (S25/hr) Travel Equipment maintenance agreements $8172 752 11771 35000 24000 2500 3000 2000 520.695 TOTAL BUDGET REQUEST $87,195 004598.007 Chemical Manufacturers Association Vinyl Chloride Health Committee P16C Dr. James A. Barter Director of Environmental Health Science PPG Industries, Inc. One PPG Place Pittsburgh, PA 15272 (412)434-2801 Fax (412)434-2137 Mr. John Gamble Westlake Chemical Corp. 2801 Post Oak Blvd. Suite 600 Houston, TX 77056 (713)960-9111 Fax (713)629-6240 Dr. Robert R. Hinderer Dir., Hlth, Tox. & Prod. Sfty The BFGoodrich Company 9911 Brecksville Road Cleveland, OH 44141-3247 (216)447-5181 Fax (216)447-5710 Colin Park, Ph.D Mgr, Issues Mgmt/Biostatistics The Dow Chemical Company 1803 Dow Center Midland, MI 48674 (517)636-1159 Fax (517)638-2425 Dr. Steven J. Phillips Occidental Chemical Corp. 5005 LBJ Freeway Rm. 904 Dallas, TX 75244-9050 (972)404-2413 Fax (972)404-3287 E-Mail STEVEN_PHILLIPS@0XY. COM Mr. Jay Strange Industrial Hygienist Georgia Gulf Corporation 26100 Highway 405 / Placmemine, T.A 70765 ~(504j39*-2642 '' -- Fax (504)687-0294 Mr. Ed Beeler Dir., Env. Health - Safety The Geon Company One Geon Center Avon Lake, OH 44012 (440)930-3030 Fax (440)458-5921 Mr. Mark A. Gruenwald Assoc. Dir., Product Safety Borden Inc. 180 E. Broad Street 15th Floor Columbus, OH 43215 (614)225-3459 Fax (614)225-7638 Mr. Caffey Norman Patton Boggs, L.L.P. 2550 M St., N.W. Washington, DC 20037 (202)457-5270 Fax (202)457-6315 Dr. David A. Penney Sr. Toxicologist, Product Sfty CONDEA Vista Company 900 Threadneedle P.0. Box 19029 Houston, TX 77079-2990 (281)588-3059 Fax (281)588-3478 Mr. David Pun Senior, Corporate Industrial Hygieni Formosa Plastics 9 Peachtree Hill Rd. Livingston, NJ 07039 (973)716-7279 Fax (973)716-7283 004598.008 Chemical Manufacturers Association Vinyl Chloride Transportation Cmte P29A Mr. Thomas G. Grumbles Manager, Product Safety & Occup. CONDEA Vista Company 900 Threadneedle P.0. Box 19029 Houston, TX 77224-9029 (281)588-3445 Fax (281)588-3478 E-Mail TGRUMBLES@CVCNET.COM Health Mr. Tom Hester PPG Industries, Inc. P.0. Box 1000 1300 Columbia Southern Rd. Lake Charles, LA 70601 (318)491-4260 Fax (318)491-4693 Mr. George Marshall Occidental Chemical Corp. 5005 LBJ Freeway Dallas, TX 75244 (512)776-8120 ^ ,, Wax'776=6845 *0- - => ^ ^ Mr. Bill Trotter The Dow Chemical Company P.O.Box 150 Building 6601 Plaquemine, LA 70764 (504)353-8809 Fax (504)353-5322 Mr. Richard H. Wagner Coordinator Transp. Sfty. Borden Packaging & Industrial 180 E. Broad Street, 24th Fir Columbus, OH 43215 (614)225-4628 Fax (614)225-4998 Mr. Bob L. Wronko Mgr, Transp. Regulatory Srvcs The Geon Company LaPorte Plant 2400 Miller Cut Off Road LaPorte, TX 77571 (281)476-8052 Fax (281)476-8081 Mr. Forrest Henson JTS Enterprises, Inc. Suite 153 4600 Post Oak Place Houston, TX 77027 (713)621-6740 Fax. (713)621-2454 Mr. Tim LeBlanc Formosa Plastics P.0. Box 271 Baton Rouge, LA 70821 (504)356-8620 Fax (504)356-8608 Ms. Carol Toth Keller and Heckman 1001 G Street, NW Suite 500 West Washington, DC 20001 (202)434-4209 Fax (202)434-4646 Mr. Frank Vendt Georgia Gulf Corporation P.0. Box 629 Hwy. 405 Plaquemine, LA 70765-0629 (504)685-2601 Fax (504)687-2442 Mr. David V. Wise Project Engineer Shintech, Inc. #24 Greenway Plaza Suite 811 Houston, TX 77046 (713)965-0713 Fax (713)627-0988 004598.009 m& Chemical Manufacturers Association January 12,1997 Dear Vinyl Chloride Health Committee Members: On last week's conference call the Committee discussed the draft Huntingdon developmental report. The comments I received in writing and over tire phone have been forwarded to Huntingdon. Copies of the comments were also sent to those members who requested them. If you haven't returned the authorization form accepting the report, please take a moment now to do so (fax number 703/741-6091). If you need another copy of the authorization form, call my staff assistant, Cynthia Barrett (703/741-5642). On the call we also discussed submitting comments on the recent proposal by the California Office of Environmental Health Hazard Assessment (OEHHA) to establish a chronic Reference Exposure Level (REL) for vinyl chloride. The chronic RELs are based on non-cancer health effects and are intended to represent ambient concentrations of compounds to which a susceptible person in the general population could be exposed for a lifetime with out adverse effects. The REL will be used in California's Air Toxics "Hot Spots" program, which requires certain facilities to conduct site-spedfic risk assessments. Please fill out the attached authorization form and return it to me by Wednesday, January 14th. The comment deadline for the RELs closes January 30th. In addition, a recent Federal Register Notice was brought to my attention (see attached). EPA is planning to submit Information Collection Requests (ICRs) to tile Office of Management and Budget The ICRs could potentially affect"... exhaust gases and oxychlorination vents at ethylene dichloride plants; exhaust gases at vinyl chloride monomer plants; and exhaust gases, reactor opening losses, manual vent valves and stripping residuals at polyvinyl chloride plants. The standards also apply to relief valves and fugitive emission sources at all three types of plants." Further on in the notice, the EPA asks for input on four specific points (Le., is the information collection necessary, is the agency's evaluation of the burden of reporting this information accurate, how could the quality, utility, and clarity of the information to be collected be enhanced, and a request for suggestions to minimize the reporting burden). Please review the notice and let me know if the VCHC should submit comments by faxing back the attached authorization form by Wednesday, January 14*. The comment deadline on this notice closes February 2nd. - Finally, we have located a meeting room for our February 10* Committee meeting in North Carolina. The meeting will be held at the offices of Patton Boggs. The meeting will be from 8:30 a.m. to 2:30 p.m. and we will have a working lunch. Hotel accommodations can be made at the Imperial Sheraton at 919/941-5050. The hotel is within walking distance of Patton Boggs. When making reservations, please mention Patton Boggs to receive the corporate rate of 1 $120/regular room or $140/upgraded room. A draft agenda for the meeting will be sent out by \ the end of the week. Please return the attached meeting attendance form by next Wednesday, \ January 21,1998 004598.010 Innovation, Technology and Responsible Care At Work 1300 Wilson Blvd., Arlington, VA 22209 Telephone 703-741-5000 Fax 703-741-6000 As always, if you have any questions, I can be reached at 703/741-5639. Sincerely, Attachments(3) Wendy K. Sherman Manager, Vinyl Chloride Health Committee 004598.011 CHEMICAL MANUFACTURERS ASSOCIATION VINYL CHLORIDE HEALTH COMMITTEE (VCHC) ACTIVITIES (3) IN Memorandum of Understanding (MOU) with the Agency for Toxic Substances and Disease Registry (ATSDR) - The Vinyl Chloride Health Committee (VCHC) signed the MOU with ATSDR in lieu of a TSCA Section 4 testing requirement. The study, which is currently being conducted, will fill a number of data gaps regarding the reproductive and developmental toxicity of vinyl chloride. Cost: $700,000 U.S. dollars * -J ,, p.' '( lUpdate of Mortality Among Vinyl Chloride Workers - This epidemiology study is ,, av* updating mortality information among vinyl chloride workers for the years 1983 through 1992. The original study and first update focused on the time periods 1942-1972 and 1973-1982, respectiyely^-Eaiijer-sStudies have shown vinyl chloride to be associated with hepati^mrgtosarcomaapafong exposed chemical workers. . ^ vJ-` K Mundt is the principle investigator>--^^_ VVw*^i- 1` Cost: $500,000 US. dollars c^JjuA Brain Cancer Study - Since the discover of an association between vinyl chloride workers and hepatic angiosarcoma, there has been speculation on the relationship of vinyl chloride with other cancers. The VCHC and K. Mundt are working with investigators at the University of Louisville to examine the possible relationship between vinyl chloride and brain cancer among exposed chemical workers. Ca-4C a.4rC> Cost: $150,000 + U.S. dollars Molecular Carcinogenesis Satellite Studies- The VCHC is supporting a series of studies at the University of North Carolina on the formation and repair of DNA adducts to elucidate the mechanisms of vinyl chloride carcinogenesis. Cost: $120,000 + U.S. dollars International Life Sciences Institute Project on Non-Tumor Data - The VCHC joined with a number of other sponsors to underwrite a project by the International Life Sciences Institute (ILSI) to use non-tumor data to quantitatively estimate cancer risk Cost: $10,000 U.S. dollars * + * ^'**7 ^ Physiologically-Based Pharmacokinetic (FBPK) Modeling - The VCHC hired a consultant to meet with the Environmental Protection Agency to discuss the use of PBPK modeling for vinyl chloride. Cost: $6,000 U.S. dollars 004598.012 VINYL CHLORIDE PANEL Hii+o'-j i" Act **/>! jL **,< Sbps~*-i*. /*fj PsrJ^ir HISTORY: The Panel was formed in 1971 by vinyl chloride manufacturers to develop and assess health and safety data on vinyl chloride. The Panel expanded its scope of activities in 1991 to address safety issues in the transportation of vinyl chloride monomer. In 1992, the Panel formed the Vinyl Chloride Transportation Network (VCNet) to provide technical expertise and assistance by the industry and contractors to emergency responders at vinyl chloride railroad transportation incidents. Shippers of vinyl chloride are able to activate the network through CHEMTREC, CMA's hazardous materials hotline. VCNet is the first mutual aid network to be formed under CHEMSTAR. VINYL CHLORIDE HEALTH COMMITTEE ACCOMPLISHMENTS: In lieu of a TSCA Section 4 testing requirement, the Committee signed a memorandum of understanding (MOU) with the Agency for Toxic Substances and Disease Registry to conduct a study of the reproductive and developmental effects of vinyl chloride. Under the MOU, the Panel is sponsoring a combined inhalation twogeneration reproduction and developmental toxicity study in CD rats. The study, which is currently in progress, will be finalized by mid-1998. The Committee is also sponsoring research at the University of North Carolina on the formation and repair of DNA adducts induced by vinyl chloride. The Committee also is continuing to work on an update of the study of mortality among vinyl chloride workers. The mortality study, first published in 1974, is being updated through the year 1994. The update provides an important opportunity to expand the knowledge base of possible health effects of occupational exposure to vinyl chloride. The Committee anticipates completing the study in the first half of 1998. The Committee is also working with researchers from the University of Louisville to examine the possible relationship between exposure to vinyl chloride and brain cancer among chemical industry workers. In an April 1996 Federal Register Notice EPA announced a request for technical information on eleven chemicals, including vinyl chloride. The notice was part of a pilot program to enhance the quality of chemical-specific information in the Agency's Integrated Risk Information System (ILSI) through peer review and increased public involvement. The Committee submitted a number of papers on the pharmacokinetic modeling of vinyl chloride exposure. An external peer review committee met in May to discuss the revised file. Following incorporation of their comments, a consensus document will be viewed by an Agency committee and then the updated file will be placed in the IRIS database. The file update expected to occur in late 1997. The Committee will continue to monitor activity on this pilot project. The Committee joined with a number of other sponsors to underwrite a project by the International Life Sciences Institute to use non-tumor data to quantitatively estimate cancer risk. Vinyl chloride is one of three chemicals being evaluated in this project Once the draft vinyl chloride case study is prepared. Committee members will meet with reviewers to discuss the study and develop recommendations on the use of non- 004598.013 tumor data in cancer risk assessment, including identification of future research needs. The meeting between Committee members and reviewers is expected to occur in early 1998. In October, Cal/EPA's Office of Environmental Health Hazard Assessment (OEHHA) published a notice announcing a public comment period for 45 candidate chemical, including vinyl chloride, for which draft data summaries and prioritizations have been assigned for carcinogenicity or reproductive toxicity concerns. In November the Committee submitted comments noting that based on the available toxicological literature, vinyl chloride was unlikely to be a developmental or reproductive toxicant. The Committee notified Cal/EPA of the combined two-generation developmental and reproductive study being conducted under the MOU with ATSDR and proposed to share the results of that study with the Agency. PLANS: Over the next year the Committee anticipates finalizing the combined twogenerational developmental and reproduction study, and the mortality update of vinyl chloride workers. The Committee will continue to support activities on the brain cancer study in chemical industry workers, the ILSI case study on using non-tumor data in risk assessments, and the DNA adduct being conducted at the University of North Carolina. The Committee will also continue to work with regulatory agencies and other concerned organizations on matters relating to health and safety aspects of vinyl chloride. VINYL CHLORIDE TRANSPORTATION COMMITTEE ACCOMPLISHMENTS: In November, members of the Vinyl Chloride Transportation Committee made a series of presentations at the CHLOREP '96 Workshop. The workshop, sponsored by the Chlorine Institute, was held in Phoenix, AZ. Presentations included a training program for emergency responders, and an overview of Committee activities. As a service to emergency responders, the Committee is producing a video on mitigating non-accidental leaks in vinyl chloride tank cars. The video. Vinyl Chloride Monomer Tank Car Leak Mitigation and Capping Kit Installation, is slated for completion by the end of 1997. In the past year the Committee has worked with the Association of American Railroads to develop designs for tank car manway covers. By coordinating activities with the AAR, the Committee is supporting the development of manway covers that are compatible with existing emergency capping kits. The Committee joined with other trade associations and CMA Task Groups in commenting on an advanced rulemaking addressing the applicability of die hazardous material regulations to chemical loading, unloading, and storage activities. The upcoming notice of proposed rulemaking on this issue is anticipated in the fall of 1997. Over the last year the Committee has also submitted comments to the US. Coast Guard on the qualifications for barge tankermen. a filed a petition with the Department of Transportation regarding the labeling of vinyl chloride rail cars, and joined CMA's / 004598.014 2_ Marine Transportation and Pipeline Task Groups in submitting comments on a proposed marine transportation related pipeline testing rulemaking. PLANS: Over the next year the Committee will update a variety of VCNet materials including the VCNet agreement, the Operations Manual, Safety Awareness Training Manual, a map of emergency responders and an educational brochure. The Committee will also continue its collaboration with the Association of American Railroads. The Committee will join with other transportation-related Task Groups at CMA to provide comments on the upcoming OPA '90 Hazardous Substances Response Plan Regulations and on the Hazardous Material Regulations to Chemical Loading, Unloading and Storage activities. Both proposed rulemakings are expected to be published this winter. 004598.015 July 29,1997 CHEMICAL MANUFACTURERS ASSOCIATION Vinyl Chloride Health Committee 1997-1998 Program Budget* &> /r~ t /YJa*'?*' Activity Proposed Budget** Molecular Research (James Swenberg, UNC) Risk Assessment (EPA/IRIS) Outside Legal Contingency 75,000 20,000 15,000 40,000 $150,000 Company Borden Chemical Dow Chemical Formosa Plastics GEON Georgia Gulf Occidental Chem PPG Industries CONDEA Vista Capacity (millions of lbs.) 935 2,960 2,160 1,400 1,260 2,509 840 970 %of Total Capacity 7.18 22,73 16.58 10.75 9.67 19.19 6.45 7.45 Pro-rata share of the 1998 Proposed Budget $ 10,770 34,095 24,870 16,125 14,515 28,785 9,675 11,175 13,025 100.0 * To cover expenses for the remainder of 1997 and all of 1998 $150,000 ** The surplus of $107,260.98 plus the interest generated would cover the estimated administrative costs of $120,000 for August to December 1997 and the calendar year 1997 (17 months) 1 004598.016 09/23/97 CHEMICAL MANUFACTURERS ASSOCIATION Vinyl Chloride Panel Health Committee Financial Statement - Phase 10 June 1993 Through July 1997 EXPENSES Activity Epidemiology Study Update Applied Epidemiology, Inc. ENSR Contingency Total Brain Cancer Case-Control Study University of Louisville Protocol Peer Review Cons.-Checkoway Protocol Peer Review Cons.-Marsh Contingency Total Reproductive, Developmental, and Mechanistic Research Studies Huntingdon Lab-Repro/Develop Huntingdon Lab - Satellite University of North Carolina-Gift University of North Carolina-Travel Related 13C2 Vinyl Chloride Synthesis GEON shipment of Vinyl Chloride Study Monitoring-D. Penney Study Monitoring - J. Knaak Contingency Total Risk Assessment Reitz Reitz Swenberg lnt'1 Life Sciences Institute Total Outside Counsel June 1994-May 1995 June 1995-May 1996 June 1996-May 1997 Total Spent/ Committed 449,895.00 9.260.92 15,844.08 120,000.00 1,125.00 1,912.50 ^3,662.50 475,000.00 584,582.00 48.092.00 50,000.00 20.695.00 11.200.00 2,737.16 1,600.62 922.22 30,171.00 597.47 4,497.96 548.40 10,000.00 6,540.10 25,164.08 10,994.13 750,000.00 15,643.83 42,698.31 Administration June 1993-May 1994 June 1994-May 1995 June 1995-May 1996 June 1996-May 1997 June 1997-July 1997 Total Direct Time 7,677.50 45,265.00 46,842.50 74,722.50 13,545.00 188,052.50 Misc.** 516.85 4,897.44 3,856.08 3,518.16 0.00 12,788.53 Total 8,194.35 50,162.44 50,698.58 78,240.66 13,545.00 200,841.03 200,841.03 Total 004598.017 $1,611,083.17 ** Includes expenses for Panel lunches, dinners, express mailings, and conference calls. 09/23/97 CHEMICAL MANUFACTURERS ASSOCIATION Vinyl Chloride Panel Health Committee Financial Statement - Phase 10 June 1993 Through July 1997 REVENUE Period June 1993-May 1994 June 1994-May 1995 June 1995-May 1996 June 1996-May 1997 June 1997-July 1997 Anticipated Revenue ENSR Total EXPENSES See Attached for details BALANCE Company Contrfoutions 24.000.00 453,353.50 628.915.00 447.865.00 * 0.00 81,374.00 14.000.00 1,649,507.50 Interest 118.14 7,225.76 23,020.04 38,472.71 0.00 0.00 0.00 68,836.65 Total $24,118.14 460,579.26 651,935.04 486,337.71 0.00 81,374.00 14,000.00 $1,718,344.15 $1,611,083.17 $107,260.98 004598.018 * The Dow Chemical Company was given a credit of $34,452 against its commitment for providing epidemiology consulting services.