Document 2RMbb2Vn369Xb2z4g4bV8JoJa
RO BER T B. A I KEN , M . D. M . P. H .
Co mmis s io n er
STATE OF VERMONT
D EP A R T M EN T O F H EA LT H
D IV ISIO N O F IN D U ST RIA L H YG IEN E
3 2 SP A U LD IN G ST. D A R R E, V ER M O N T
In Repl y Pl ea se Ad d r e s s
p. o . b o x se e
607
D A R R E, V ER M O N T 0 5 6 4 1
T EL. S0 2 476-4071
Oct ober 6, 1967
Dr . Rober t A. Kehoe The Ket t er i ng Labor at or y Uni v. of Ci nci nnat i Medi cal Ci nci nnat i , Ohi o
Col l ege
Dear Dr . Kehoe:
The Lead I ndust r i es Associ at i on has pr epar ed a dr af t r ecommendat i on t o Z 37 of USASI whi ch set s t he TLV f or Lead Chr omat e at 0. 5 mgms per cubi c met er . 1 have been asked t o par t i ci pat e i n t he del i ber at i ons on t hi s.
Bef or e maki ng any j udgement ! wr ot e t o Dr , St ok i nger and al so spok e t o hi m on t he mat t er . He was unabl e t o hel p me r el at i ve t o dat a whi c h mi ght val i dat e t hi s st andar d. Dur i ng t he c onv er s at i on t he obs er v at i on was made t hat si nce l ead chr omat e has a ver y l ow s ol ubi l i t y i n wat er ( about 6 mi cr ogr ams per 100 ml . i n wat er at r oom t emper at ur e) i t i s r el at i vel y i nsol ubl e and hence j ust i f i es t he TLV r ecommendat i on. However , Dr . St oki nger coul d not cl ar i f y t he quest i on of s ol ubi l i t y or t hi s compound i n al veol ar f l ui d. That dat um woul d be per t i nent . He s ugges t ed t hat per haps you mi ght be of hel p En cl ar i f yi ng t he pr obl em.
What ar e t he cr i t er i a whi ch val i dat e t he r ecommendat i on t hat l ead chr omat e ( yel l ow) i s compar at i vel y of much l ower t oxi c i t y t o t he l ungs t han ei t her l ead or chr omat e?
1 hope t hat you can i l l umi nat e t hi s quest i on.
BL: I mb
Cor di al l y your s,
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Benj ami n Lev a di e
Vi ^e/ Chat r man, AST&M D 22
N13930
K 0012183