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GENERAL CHEMICAL EXPOSURE
(1) MONSANTO STUDY - J. Killeen (3/78)
SCOPE; - 565 former Monsanto employees.
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OBJECTIVES:
- Proportional mortality analysis of cancer deaths by site and occupational exposure.
CONCLUSIONS:
- No statistically significant excesses in (9) digestive categories.
- No apparent prostate cancer excesses in department.
- No prior reasons for suspecting excess genital, diges
tive cancer deaths.
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- Non-statistically significant excess in digestive genital cancer deaths.
(2) NIOSH STUDY - R. Snirtas (7/78) SCOPE:
- 465 death certificates of 484 employee deaths between 1950 and 1976.
OBJECTIVES:
- Epidemiological study of employee deaths based upon PMR & PCMR by race, site, age, exposure period, and national origin.
CONCLUSIONS:
- Slight excess of digestive, genito-urinary cancer, not associated to specific etiologic agent. Not statisti cally significant when compared to Hampden county rates.
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o GENERAL CHEMICAL EXPOSURE (Coat)
(3) STUDY/VISIT BY PETERS/MONSON (6/78) SCOPE:
(OSflA Health Hazard Survey)
- Analysis/Evaluation o (2) prior studies: Monsanto (Killeen) NIOSH (Spirtas)
OBJECTIVES:
- Determine whether further studies or medical evaluations are necessary.
CONCLUSIONS:
- Data from both studies are consistent with no demonstrable effect of working at Springfield Plant in cause of death.
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(4) UNIVERSITY OF PITTSBURGH STUDY - MARSH (12/79) SCOPE: - 2490 total cohort of employees during period 1949 - 1966. OBJECTIVES:
. - Analyze long-term, cause-specific mortality patterns for Monsanto-Springfield employees and ex-employees and com pare to mortality experience among general populations in U.S~, Massachusetts., and Hampden County.
CONCLUSIONS
- Fewer deaths from any cause ... less than expected.
- Fewer deaths from all forms of cancer
than expected.
- Slightly more deaths from digestive and genito-urinary cancers ... than expected.
- No new evidence was uncovered to show any worker-health
problem at Springfield Plant. (
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GENERAL CHEMICAL EXPOSURE (Cone)
(5) (UNIVERSITY OF PITTSBURGH STUDY (B) MARSH (10/81)
SCOPE;
- 2479 total cohort of employees and ex-employees during period 1950 - 1976.
OBJECTIVES:
- Determine if any association exists between digestive, genito-urinary cancers and certain chemical agents and/ or conditions specific to work environment.
CONCLUSIONS:
- Methodological problems, small numbers, and questionable exposures did not permit definite conclusion.
- Statistically significant rectal cancer excess, and nearly statistically significant prostate cancer excesses in specific DEC ... may warrant further study.
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(6) UNIVERSITY OF MASSACHUSETTS MASTER THESIS - T. Liebling (2/82) SCOPE; - 211 total cohort of employees during period 1976-1980. OBJECTIVES; - Identify any excess mortality associated with particular chemical exposures or work areas in the plant. CONCLUSIONS; - Significant excess of buccal/pharyngeal cancer observed in employees who may have been exposed to formaldehyde.
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