Document 2R9K8yN1KL0M74X8yeLkeVzYN

PX-12^7 28 Table 7.____ Toxic Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin In Man.0- Effects__________________________________________________ _______________ DERMATOLOGICAL Chloracne Porphyria cutanea tarda Hyperpigmentation and hirsutism INTERNAL Liver damage^ Elevated serum hepatic enzyme levels Disorders of fat metabolism Disorders of carbohydrate metabolism Cardiovascular disorders Urinary tract disorders Respiratory disorders Pancreatic disorders EUROLOGICAL Polyneuropathies (perpheral neuritis) Lower extremity weakness Sensory impairments (sight, hearing, smell, taste) CONFIDENTIAL SUBJECT. TO PROTECTIVE ORDER. SYCHIATRIC Neurasthenic or depressive syndromes_____________________________________ Source: Huff, Moore, Saracci, and Tomatis, 1980 iild fibrosis, fatty changes, hemofuscin deposition and parenchymal-cell degeneration were observed in a few cases.